Long-Time Course of Idiopathic Small Fiber Neuropathy.

Abstract:

BACKGROUND:Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in patients with unknown underlying cause may increase the yield of treatable causes of SFN. METHODS:We evaluated 16 patients with documented long-time course of idiopathic SFN. RESULTS:Clinical and electrophysiological course remained stable in 75% of the patients, while 25% SFN-patients developed large fiber neuropathies. CONCLUSIONS:Our data suggest that SFN represents a benign disease course in the majority of patients without severely limiting the quality of life.

journal_name

Eur Neurol

journal_title

European neurology

authors

Flossdorf P,Haupt WF,Brunn A,Deckert M,Fink GR,Lehmann HC,Wunderlich G

doi

10.1159/000487717

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

161-165

issue

3-4

eissn

0014-3022

issn

1421-9913

pii

000487717

journal_volume

79

pub_type

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