Abstract:
BACKGROUND/AIMS:It is generally assumed that silent brain infarction (SBI) and symptomatic lacunar infarction (sLAC) share common vascular risk factors and their pathogeneses are known to be similar. However, few studies have conducted a risk factor profile analysis of the two diseases in a single study design. METHODS:This study included 64 subjects with SBI lesions, 140 patients with sLAC, and 342 controls by retrospective investigation of brain MRI. Topographic findings and vascular risk factor profiles were compared. RESULTS AND CONCLUSION:Compared to the controls, the SBI group was found to be associated with hypertension (p = 0.002) and elevated plasma total homocysteine level (p = 0.02). The sLAC group was found to be associated with hypertension (p = 0.001), diabetes (p = 0.004), smoking (p = 0.002), ischemic heart disease (p = 0.01) and hyperlipidemia (p = 0.04). In the present study, risk factor profiles of the SBI and sLAC were not exactly the same, indicating a different pathogenesis between the two diseases.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Kim MH,Moon JS,Park SY,An SA,Kim OJ,Kim NK,Oh SHdoi
10.1159/000324335subject
Has Abstractpub_date
2011-01-01 00:00:00pages
250-6issue
5eissn
0014-3022issn
1421-9913pii
000324335journal_volume
65pub_type
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更新日期:2000-01-01 00:00:00
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pub_type: 传,历史文章,杂志文章
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更新日期:2012-01-01 00:00:00
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