Rate of cerebral embolic events in relation to antibiotic and anticoagulant therapy in patients with bacterial endocarditis.

Abstract:

:To quantitate embolic risk we studied a retrospective series of 61 patients with strictly defined bacterial endocarditis. Eighteen patients had neurological complications attributable to cerebral embolism. Seventeen embolic episodes occurred prior to antibiotic treatment and 8 episodes after its commencement. The rate of embolism per patient-week during a 20-week observation period showed a highly significant almost 4-fold reduction to a low level soon after antibiotics were started. Patients already on anticoagulation for prosthetic valves had the same embolic risk as those not so treated. The evidence suggests that anticoagulation at the time of diagnosis of bacterial endocarditis is not warranted.

journal_name

Eur Neurol

journal_title

European neurology

authors

Paschalis C,Pugsley W,John R,Harrison MJ

doi

10.1159/000117317

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

87-9

issue

2

eissn

0014-3022

issn

1421-9913

journal_volume

30

pub_type

杂志文章
  • Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.

    abstract::Cerebrospinal fluid metabolites of dopamine, norepinephrine and serotonin were studied in two groups of left temporal lobe epileptic patients, the only difference between the two groups being that one group had paranoid schizophrenic symptomatology. Homovanillic acid accumulation was decreased in this group. This find...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115048

    authors: Peters JG

    更新日期:1979-01-01 00:00:00

  • Multidisciplinary management of multiple sclerosis symptoms.

    abstract:BACKGROUND:Effective management of multisymptomatic chronic diseases such as multiple sclerosis (MS) requires a multimodal, interdisciplinary approach. At MS clinics, numerous healthcare specialties are coordinated to provide patients with quality clinical care for all aspects of their disease. Settings and resource av...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000367620

    authors: Gallien P,Gich J,Sánchez-Dalmau BF,Feneberg W

    更新日期:2014-01-01 00:00:00

  • Extracranial Venous Drainage Pattern in Multiple Sclerosis and Healthy Controls: Application of the 2011 Diagnostic Criteria for Chronic Cerebrospinal Venous Insufficiency.

    abstract::The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000445540

    authors: Cardaioli G,Di Filippo M,Bianchi A,Eusebi P,Di Gregorio M,Gaetani L,Gallina A,Calabresi P,Sarchielli P

    更新日期:2016-01-01 00:00:00

  • Renal clearance of pyridostigmine in patients with myasthenia gravis.

    abstract::The urinary clearance of pyridostigmine was studied in six patients with myasthenia gravis. In three patients on pyridostigmine alone, renal clearance ranged from 349 to 481 ml/min, corresponding to a pyridostigmine:creatinine clearance ratio of 2.64 to 3.46. In a patient on bendrofluazide as well as pyridostigmine, a...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114882

    authors: Chan K,Calvey TN

    更新日期:1977-01-01 00:00:00

  • Cognitive and demographic determinants of dementia in depressed patients with subjective memory complaints.

    abstract:BACKGROUND:Previous studies showed that late-life depression with subjective memory complaints (SMC) may be associated with an increased risk of developing dementia. However, not all such patients have cognitive decline. The aim of this longitudinal study was to identify possible clinical determinants of progressive de...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000090104

    authors: von Gunten A,Giannakopoulos P,Duc R

    更新日期:2005-01-01 00:00:00

  • Management of cerebral arteriovenous malformations associated with symptomatic congestive intracranial hypertension.

    abstract::We report on management strategies and clinical outcomes in 4 cases of acute symptomatic congestive intracranial hypertension associated with cerebral arteriovenous malformations (AVMs). Congestion resulted from high-volume shunts exhausting the drainage capacity of the cerebral venous system in 3 patients, and from s...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000109263

    authors: Rosenkranz M,Regelsberger J,Zeumer H,Grzyska U

    更新日期:2008-01-01 00:00:00

  • Transient ischaemic attack: a common initial manifestation of cardiac myxomas.

    abstract:BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000052116

    authors: Alvarez-Sabín J,Lozano M,Sastre-Garriga J,Montoyo J,Murtra M,Abilleira S,Codina A

    更新日期:2001-01-01 00:00:00

  • Morel's laminar sclerosis.

    abstract::A 49-year-old alcoholic woman was admitted for convulsions. She died after a 4-week clinical course characterized by a persistent coma with diffuse muscular hypertonia. Post-mortem examination of the brain demonstrated a spongy degeneration and gliosis of the cerebral cortex, limited to the 3rd and the 4th layers. No ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114939

    authors: Naeije R,Franken L,Jacobovitz D,Flament-Durand J

    更新日期:1978-01-01 00:00:00

  • Effectiveness of low-frequency rTMS and intensive speech therapy in poststroke patients with aphasia: a pilot study based on evaluation by fMRI in relation to type of aphasia.

    abstract:AIM:To assess the safety and clinical efficacy of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with intensive speech therapy (ST) in poststroke patients with aphasia. SUBJECTS AND METHODS:Twenty-four patients with left-hemispheric stroke and aphasia were subjected. During 11-day hospit...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000338773

    authors: Abo M,Kakuda W,Watanabe M,Morooka A,Kawakami K,Senoo A

    更新日期:2012-01-01 00:00:00

  • Primary intracerebral hemorrhages in the Besançon stroke registry. Initial clinical and CT findings, early course and 30-day outcome in 350 patients.

    abstract::The purpose of this study was to estimate the risk factors, early course, outcome and neuroimaging patterns in primary intracerebral hemorrhages (PIH). Using the Besançon Stroke Registry, 350 patients with first PIH documented by computed tomography (CT) between 1987 and 1993 were included in the present study. Patien...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000008177

    authors: Tatu L,Moulin T,El Mohamad R,Vuillier F,Rumbach L,Czorny A

    更新日期:2000-01-01 00:00:00

  • Effect of hypocapnia on cerebral oxygen metabolism and blood flow in ischemic cerebrovascular disorders.

    abstract::Effects of hypocapnia on cerebral oxygen consumption (CMRO2) and blood flow (CBF) in cerebral ischemia were studied in 19 patients. The CMRO2 did not change significantly during hypocapnia within the whole group of patients, because 10 out of 19 cases showed a decrease (p less than 0.001) and other 9 showed an increas...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116149

    authors: Tsuda Y,Kimura K,Yoneda S,Hartmann A,Etani H,Hashikawa K,Kamada T

    更新日期:1987-01-01 00:00:00

  • Multiphasic perfusion computed tomography as a predictor of collateral flow in acute ischemic stroke: comparison with digital subtraction angiography.

    abstract:BACKGROUND:Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS:Conse...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000334867

    authors: Kim SJ,Noh HJ,Yoon CW,Kim KH,Jeon P,Bang OY,Kim GM,Chung CS,Lee KH

    更新日期:2012-01-01 00:00:00

  • Characteristics and outcomes of patients with seizures according to the time of onset in relation to stroke.

    abstract:BACKGROUND/AIM:Although most late-onset seizures (LS) appear within 2 years after stroke, some of them occur later and their characteristics are unknown. The aim of this study was to compare the characteristics of patients with very-late-onset seizures (VLS) to those with early-onset seizures (ES) and those with LS. P...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115635

    authors: De Reuck J,Sieben A,Van Maele G

    更新日期:2008-01-01 00:00:00

  • Effects of medial temporal atrophy and white matter hyperintensities on the cognitive functions in patients with Alzheimer's disease.

    abstract:AIMS:We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer's disease (AD) patients and the interaction between MTA and WMH. METHODS:From 13 centers, a total of 216 AD patients were consecutivel...

    journal_title:European neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000329277

    authors: Shim YS,Youn YC,Na DL,Kim SY,Cheong HK,Moon SY,Park KW,Ku BD,Lee JY,Jeong JH,Kang H,Kim EJ,Lee JS,Go SM,Kim SH,Cha KR,Seo SW

    更新日期:2011-01-01 00:00:00

  • The Topography of Cortical Microinfarcts in Neurodegenerative Diseases and in Vascular Dementia: A Postmortem 7.0-Tesla Magnetic Resonance Imaging Study.

    abstract:BACKGROUND:Cortical microinfarcts (CoMIs) are considered as barely visible lesions in clinical-neuroradiological correlation studies. On postmortem 7.0-tesla MRI, however, CoMIs of different size are easily detected. SUMMARY:The present MRI study investigates 84 postmortem brains with different neurodegenerative disea...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000447297

    authors: De Reuck JL,Auger F,Durieux N,Cordonnier C,Deramecourt V,Pasquier F,Maurage CA,Leys D,Bordet R

    更新日期:2016-01-01 00:00:00

  • Multiple sclerosis. A clinical study of 70 cases.

    abstract::70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115267

    authors: Zhao BX,Liu XQ,Guo YP,Yang YC,Huang HF

    更新日期:1981-01-01 00:00:00

  • Thalamic Lesions Caused by Deep Cerebral Venous Thrombosis: A Retrospective Study.

    abstract:BACKGROUND:Thalamic lesion due to deep cerebral venous thrombosis (DCVT) is an uncommon cause of stroke. Until now, only a few case reports have been published. The aim of the study is to report the clinical and radiological findings of thalamic lesion with DCVT. METHODS:We reviewed our computerized stroke database of...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000439167

    authors: Caplan LR,Wang Q

    更新日期:2015-01-01 00:00:00

  • Peripheral neuropathy of Machado-Joseph disease in Taiwan: a morphometric and genetic study.

    abstract::Machado-Joseph disease (MJD) is a dominantly inherited cerebellar ataxia associated with spasticity, ophthalmoplegia, dystonia and peripheral neuropathy. Presented here are 5 MJD cases. A morphometric analysis of the histopathology of their sural nerves was carried out to know the relationship between axon size and my...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000066169

    authors: Lin KP,Soong BW

    更新日期:2002-01-01 00:00:00

  • Revisiting Clinical Utility of Chest Radiography and Electrocardiogram to Determine Ischemic Stroke Subtypes: Special Reference on Vascular Pedicle Width and Maximal P-Wave Duration.

    abstract:BACKGROUNDS:It is often difficult to diagnose stroke subtypes at admission, particularly in sinus rhythm cases. Vascular pedicle width (VPW) on chest X-ray (CXR) and maximal P-wave duration (P-max) on electrocardiogram (ECG) are again realized as useful parameters reflecting intravascular volume and atrial conduction s...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000382127

    authors: Sugie M,Kamiya Y,Iizuka N,Murakami H,Kawamura M,Ichikawa H

    更新日期:2015-01-01 00:00:00

  • Cognitive, but not mood dysfunction develops in multiple sclerosis during 7 years of follow-up.

    abstract::Long-term development of psychological deficits in disability-free early multiple sclerosis (MS) was evaluated in 27 female patients over a period of 7 years and compared with healthy controls. Physical and cognitive parameters deteriorated significantly but not depression scores. In particular, the self-assessed soma...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000079937

    authors: Haase CG,Tinnefeld M,Daum I,Ganz RE,Haupts M,Faustmann PM

    更新日期:2004-01-01 00:00:00

  • Transcriptome-wide characterization of gene expression associated with unruptured intracranial aneurysms.

    abstract:BACKGROUND:The biological mechanisms by which cerebral aneurysms emerge, enlarge and rupture are not totally understood. In the present study, we analyzed the genome-wide gene expression profile in human intracranial aneurysms using cDNA microarrays. METHODS:Affymetrix HU133 Plus 2.0 microarrays were used to compare g...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000236911

    authors: Li L,Yang X,Jiang F,Dusting GJ,Wu Z

    更新日期:2009-01-01 00:00:00

  • Clinical and CSF findings in multiple sclerosis patients with or without IgG oligoclonal bands at isoelectric focusing examination of CSF and serum proteins.

    abstract::The IgG oligoclonal bands in CSF can be found in high percentage of MS patients but the existence of a limited number of cases with CSF normal IgG profile is known as well. In the present study 63 out of 70 patients with definite MS and 24 out of 35 with probable MS had oligoclonal bands in the CSF at the isoelectric ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115534

    authors: Rocchelli B,Poloni M,Mazzarello P,Delodovici M

    更新日期:1983-01-01 00:00:00

  • Blood Pressure Variability in Acute Ischemic Stroke: Influence of Infarct Location in the Insular Cortex.

    abstract:BACKGROUND:The aim of this study was to elucidate the influence of insular infarction on blood pressure (BP) variability and outcomes according to the region of the insular cortex affected. METHODS:A total of 90 patients diagnosed with acute unilateral ischemic stroke were registered. The BP variability was calculated...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000486306

    authors: Kitamura J,Ueno H,Nagai M,Hosomi N,Honjo K,Nakamori M,Mukai T,Imamura E,Nezu T,Aoki S,Ohshita T,Nomura E,Wakabayashi S,Maruyama H,Matsumoto M

    更新日期:2018-01-01 00:00:00

  • Isolated so-called apraxia of eyelid opening: report of 10 cases and a review of the literature.

    abstract::So-called apraxia of eyelid opening (scAEO) has been described chiefly in the context of extrapyramidal disorders. We described 10 new patients with scAEO developing in the absence of any other CNS sign and reviewed the 11 cases with isolated scAEO reported in the literature. Combining our patients and those from the ...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000007935

    authors: Defazio G,Livrea P,Lamberti P,De Salvia R,Laddomada G,Giorelli M,Ferrari E

    更新日期:1998-01-01 00:00:00

  • Multiple sclerosis in childhood: report of 16 cases.

    abstract::Sixteen children with definite multiple sclerosis (MS; aged 6-17 years, mean 11.4 +/- 2.7; 8 boys, 8 girls) were reviewed. Cerebellar symptoms and signs were frequent at initial presentation. Among laboratory studies, the cerebrospinal fluid (CSF) IgG index or oligoclonal bands were informative in 75%, evoked potentia...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000117213

    authors: Selcen D,Anlar B,Renda Y

    更新日期:1996-01-01 00:00:00

  • Paralysis of upward gaze as a presenting symptom of vitamin B12 deficiency.

    abstract::A 47-year-old woman presented with paralysis of upward gaze associated with Addison's pernicious anaemia. Administration of cyanocobalamin resulted in significant improvement of eye movements and haematological parameters. Isolated paralysis of upward gaze may be a feature of vitamin B12 deficiency. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115702

    authors: Sandyk R

    更新日期:1984-01-01 00:00:00

  • Thalamic infarcts in young adults: relationship between clinical-topographic features and pathogenesis.

    abstract:BACKGROUND:Most reports on thalamic infarcts have focused on clinicoanatomical correlations while the mechanisms of stroke have rarely been investigated. Moreover, most series have included mainly elderly stroke patients, whereas scarce information is available about the etiology of thalamic infarcts in the young. OBJ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000047944

    authors: Pezzini A,Del Zotto E,Archetti S,Albertini A,Gasparotti R,Magoni M,Vignolo LA,Padovani A

    更新日期:2002-01-01 00:00:00

  • Protein analysis in cerebrospinal fluid. III. Relation to blood-cerebrospinal fluid barrier function for formulas for quantitative determination of intrathecal IgG production.

    abstract::To examine the possible influence of the blood-CSF barrier function on mathematical formulas for estimating intrathecal IgG production (IgG index, Tourtellotte's formula [TOURT], Schuller and Sagar's formula [Schull], and Reiber and Felgenhauer's formula [IgG(loc)]), we analysed serum and CSF samples from 105 healthy ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116920

    authors: Blennow K,Fredman P,Wallin A,Gottfries CG,Skoog I,Wikkelsö C,Svennerholm L

    更新日期:1993-01-01 00:00:00

  • Motor fluctuations in levodopa treatment: clinical pharmacology.

    abstract::Fluctuations in motor performance and dyskinesias are a common problem in the long-term management of Parkinson's disease. The pharmacokinetics and the pharmacodynamics of levodopa, loss of presynaptic dopamine terminals, alterations in postsynaptic dopamine receptor sensitivity, or changes in the modulatory influence...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000118882

    authors: Stocchi F,Bonamartini A,Vacca L,Ruggieri S

    更新日期:1996-01-01 00:00:00

  • Ultrastructural Changes of Brain Tissues Surrounding Hematomas after Intracerebral Hemorrhage.

    abstract::Our knowledge about pathophysiology of intracerebral hemorrhage (ICH) mainly originates from preclinical models of ICH. In this study, cerebral ultrastructure surrounding hematoma and its correlation with clinical severity were investigated in ICH patients. Thirty patients with basal ganglia hemorrhage and 6 control s...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000434631

    authors: Wang KY,Wu CH,Zhou LY,Yan XH,Yang RL,Liao LM,Ge XM,Liao YS,Li SJ,Li HZ,Gao LL,Lin JS,Huang SY

    更新日期:2015-01-01 00:00:00