Cognitive and demographic determinants of dementia in depressed patients with subjective memory complaints.

Abstract:

BACKGROUND:Previous studies showed that late-life depression with subjective memory complaints (SMC) may be associated with an increased risk of developing dementia. However, not all such patients have cognitive decline. The aim of this longitudinal study was to identify possible clinical determinants of progressive deterioration in depressed elderly patients with SMC. METHOD:Forty-one consecutive patients referred to a memory clinic because of persistent SMC were investigated and received an ICD-10 diagnosis of mild to moderate depression. Over a mean follow-up period of 15 months, 9 of them (22%) developed dementia. Statistical analysis included Mann-Whitney U and Fisher's exact tests as well as univariate and multivariate logistic regression analyses to assess the relationship between cognitive decline and clinical, demographical and neuropsychological characteristics at baseline. RESULTS:Age at baseline was associated with subsequent dementia, and performance on immediate verbal prose recall and a visual organization test at the initial assessment were worse in those who showed cognitive decline. In a multivariate model, age and immediate recall predicted 32.7% of the cognitive variability, with an additional 2.4% when a visual organization test was added. There was no correlation between cognitive performance and severity of depression at baseline. The study was limited by a small sample size, the nondistinction of depressive subtypes and the absence of a formal neuropsychological assessment on follow-up. CONCLUSION:Impairment of the executive component of working memory as well as limited access to visual knowledge may predict cognitive deterioration in depressed patients with subjective memory complaints.

journal_name

Eur Neurol

journal_title

European neurology

authors

von Gunten A,Giannakopoulos P,Duc R

doi

10.1159/000090104

keywords:

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

154-8

issue

3

eissn

0014-3022

issn

1421-9913

pii

90104

journal_volume

54

pub_type

杂志文章
  • Wegener's granulomatosis with nervous system involvement: a hospital-based study.

    abstract:BACKGROUND:The aim of this study was to ascertain the clinical manifestations of granulomatosis with polyangiitis (Wegener's) (GPA) with the involvement of the peripheral nervous system (PNS) and central nervous system (CNS). SUMMARY:All neurologic inpatients in a hospital over a 12-year period were reviewed. Nine pat...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000375492

    authors: Huang YH,Ro LS,Lyu RK,Chang HS,Wu YR,Chang KH,Kuo HC

    更新日期:2015-01-01 00:00:00

  • Corpus callosum atrophy--a simple predictor of multiple sclerosis progression: a longitudinal 9-year study.

    abstract:AIM:To determine whether corpus callosum atrophy predicts future clinical deterioration in multiple sclerosis. METHODS:In 39 multiple sclerosis patients the area of corpus callosum in the sagittal plane, T2 and T1 lesion volumes, brain parenchymal fraction and brain atrophy were determined at baseline and 1 year after...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000337683

    authors: Vaneckova M,Kalincik T,Krasensky J,Horakova D,Havrdova E,Hrebikova T,Seidl Z

    更新日期:2012-01-01 00:00:00

  • Morphologic aspects of the neurofibrosarcoma (neurogenic sarcoma).

    abstract::Two cases of malignant tumours of the nerve sheaths are reported. In the first patient, who had von Recklinghausen's disease, light- and electron-microscopic investigations showed an undifferentiated mesenchymal tumour of the radial nerve with the property of producing collagen fibres, an aspect characteristic of sarc...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114873

    authors: Vuia O

    更新日期:1977-01-01 00:00:00

  • Extracranial Venous Drainage Pattern in Multiple Sclerosis and Healthy Controls: Application of the 2011 Diagnostic Criteria for Chronic Cerebrospinal Venous Insufficiency.

    abstract::The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000445540

    authors: Cardaioli G,Di Filippo M,Bianchi A,Eusebi P,Di Gregorio M,Gaetani L,Gallina A,Calabresi P,Sarchielli P

    更新日期:2016-01-01 00:00:00

  • Different risk factor profiles between silent brain infarction and symptomatic lacunar infarction.

    abstract:BACKGROUND/AIMS:It is generally assumed that silent brain infarction (SBI) and symptomatic lacunar infarction (sLAC) share common vascular risk factors and their pathogeneses are known to be similar. However, few studies have conducted a risk factor profile analysis of the two diseases in a single study design. METHOD...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000324335

    authors: Kim MH,Moon JS,Park SY,An SA,Kim OJ,Kim NK,Oh SH

    更新日期:2011-01-01 00:00:00

  • Long-Time Course of Idiopathic Small Fiber Neuropathy.

    abstract:BACKGROUND:Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in p...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000487717

    authors: Flossdorf P,Haupt WF,Brunn A,Deckert M,Fink GR,Lehmann HC,Wunderlich G

    更新日期:2018-01-01 00:00:00

  • Improved visual hallucination by donepezil and occipital glucose metabolism in dementia with Lewy bodies: the Osaki-Tajiri project.

    abstract::Deficits in the cholinergic system are pronounced in dementia with Lewy bodies (DLB) and are more severe in patients with visual hallucinations (VHs). The aim is to identify the occipital glucose metabolism patterns by positron emission tomography (PET) and the changes following donepezil treatment. 13 DLB patients wi...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000322121

    authors: Satoh M,Ishikawa H,Meguro K,Kasuya M,Ishii H,Yamaguchi S

    更新日期:2010-01-01 00:00:00

  • Autosomal dominant familial Parkinson disease: older onset of age, and good response to levodopa therapy.

    abstract::Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000113460

    authors: Hasegawa K,Kowa H

    更新日期:1997-01-01 00:00:00

  • Association between Pre-Existing Coronary Artery Disease and 5-Year Mortality in Stroke Patients with High-Grade Carotid Artery Stenosis.

    abstract:BACKGROUND:The coincidence of coronary artery disease (CAD) and carotid artery stenosis (CAS) was observed. However, the association between pre-existing CAD and ischemic stroke (IS) outcome in patients with high-grade CAS remains unclear. We aimed to investigate the association between pre-existing CAD and outcomes of...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000512407

    authors: Wu CI,Wu CL,Su FC,Lin SW,Huang WY

    更新日期:2020-12-23 00:00:00

  • Chorea and systemic lupus erythematosus. A critical review.

    abstract::A critical analysis of cases of systemic lupus erythematosus (SLE) and chorea is presented. Choreatic movements occurred early in the course of the disease in most cases; the duration varied from several days to 3 years. No sex predominance was found and no relationship could be demonstrated between chorea and other n...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115743

    authors: Bruyn GW,Padberg G

    更新日期:1984-01-01 00:00:00

  • The mechanism of ipsilateral ataxia in lacunar hemiparesis: SPECT perfusion imaging.

    abstract:BACKGROUND AND PURPOSE:Although ataxic hemiparesis is a common lacunar syndrome, the precise mechanism underlying hemiataxia is not clear. We attempted to identify ataxia-related, cerebral blood flow changes in patients presenting with ataxic hemiparesis after acute capsular infarct. METHODS:We used 99mTc-ECD brain pe...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000369009

    authors: Yamamoto R,Johkura K,Nakae Y,Tanaka F

    更新日期:2015-01-01 00:00:00

  • Frontal stroke syndromes.

    abstract::The frontal lobe is the largest lobe of the brain, and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas. This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkabl...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000117068

    authors: Bogousslavsky J

    更新日期:1994-01-01 00:00:00

  • Unusual manifestations of basilar artery ectasia.

    abstract::Three patients with unusual presentations of basilar artery ectasia are described: subarachnoid hemorrhage was manifest in one and autonomic dysfunction developed in the other two. Aneurysmal rupture was the cause in the first patient, while compression of the brainstem and/or of the baroreceptor afferences of the IXt...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116299

    authors: Nogues M,Casas Parera I,Starkstein S,Micheli F

    更新日期:1988-01-01 00:00:00

  • Diagnosis of Vertigo and Dizziness Syndromes in a Neurological Outpatient Clinic.

    abstract:BACKGROUND:Dizziness and vertigo are frequent complaints of outpatients in the neurological department. Our objective was to explore the epidemiological category and clinical features of patients with dizziness or vertigo in the neurological outpatient department of a tertiary hospital. METHODS:We consecutively recrui...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000489639

    authors: Pan Q,Zhang Y,Long T,He W,Zhang S,Fan Y,Zhou J

    更新日期:2018-01-01 00:00:00

  • Stroke prediction after transient ischemic attacks in patients admitted to a stroke unit.

    abstract:BACKGROUND:Transient ischemic attacks (TIAs) bear a presumed high risk of early recurrence of stroke. Data in the literature, however, are inconsistent, as recurrence rates range from 9.5 to 20%, at 90 days. AIMS:The study was designed to determine the risk of stroke after TIA. METHODS:94 consecutive patients referre...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000332999

    authors: Tari Capone F,Cavallari M,Casolla B,Caselli G,Pieroni A,Di Lazzaro V,Napolitano S,Stanzione P,Puca E,Toni D,Rasura M,Orzi F

    更新日期:2012-01-01 00:00:00

  • Brainstem involvement in hypertensive encephalopathy: a report of two cases and literature review.

    abstract::The cerebral hemispheres show prominent involvement in hypertensive encephalopathy far more frequently than the brainstem. Two patients with severe paroxysmally accelerated hypertension associated with brainstem hyperintensity in T2-weighted magnetic resonance images are presented. Both present hyperintense lesions im...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000100015

    authors: Uchino M,Haga D,Nomoto J,Mito T,Kuramitsu T

    更新日期:2007-01-01 00:00:00

  • Neurology and Don Quixote.

    abstract::Don Quixote de la Mancha, which is considered one of the most important and influential works of Western modern prose, contains many references of interest for almost all of the medical specialties. In this regard, numerous references to neurology can be found in Cervantes' immortal work. In this study, we aimed to re...

    journal_title:European neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1159/000341338

    authors: Palma JA,Palma F

    更新日期:2012-01-01 00:00:00

  • Spontaneous pain, hyperpathia and wasting of the hand due to parietal lobe haemorrhage.

    abstract::A woman who had spontaneous pain, hyperpathia and wasting of her left hand due to a subcortical lesion in the right parietal lobe is reported. The presentation and evaluation of this most unusual case are discussed. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115753

    authors: Sandyk R

    更新日期:1985-01-01 00:00:00

  • Contribution of PET studies in diagnosis of corticobasal degeneration.

    abstract::Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000008187

    authors: Lutte I,Laterre C,Bodart JM,De Volder A

    更新日期:2000-01-01 00:00:00

  • Guillain-Barré syndrome associated with acute cytomegalovirus mononucleosis syndrome.

    abstract::A case of Guillain-Barré syndrome (GBS) in a young patient who suffered from an acute cytomegalovirus (CMV) infection is presented. The diagnosis was reached following the isolation of the virus from the urine and the demonstration of high titers of both IgM and IgG antibodies in the serum. In contrast to previous cas...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115736

    authors: Mozes B,Pines A,Sayar Y,Kaplinsky N,Frankl O

    更新日期:1984-01-01 00:00:00

  • Progressive multifocal leukoencephalopathy of the posterior fossa in an AIDS patient: clinical, radiographic and evoked potential findings.

    abstract::A 39-year-old intravenous drug user presented with dysarthria and a syndrome of the left cerebellar hemisphere. While in hospital, he developed progressive brainstem findings. Repeated CT scans revealed a lucency in the white matter of the left cerebellar hemisphere. Brainstem auditory and short-latency somatosensory ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116280

    authors: Lipton RB,Krupp L,Horoupian D,Hershkovitz S,Arezzo JC,Kurtzberg D

    更新日期:1988-01-01 00:00:00

  • Total recovery after bilateral paramedian thalamic infarct.

    abstract::Bilateral paramedian thalamic infarcts are characterised initially by the association of acute vigilance disorders and vertical gaze palsy, followed by persisting dementia with severe mnemic disturbance, global aspontaneity and apathy. We describe a patient with a dramatic neuropsychological recovery, confirmed by tes...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000008239

    authors: Krolak-Salmon P,Croisile B,Houzard C,Setiey A,Girard-Madoux P,Vighetto A

    更新日期:2000-01-01 00:00:00

  • Antibody-induced failure of botulinum toxin type B therapy in de novo patients.

    abstract::Botulinum toxin type B (BT-B) therapy failure due to formation of botulinum toxin type B antibodies (BT-B-AB) has only been reported in patients with botulinum toxin type A antibodies (BT-A-AB). We are reporting BT-B-AB-induced therapy failure in 2 patients with no previous exposure to botulinum toxin. In patient 1 co...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000081463

    authors: Dressler D,Bigalke H

    更新日期:2004-01-01 00:00:00

  • Treatment of early Parkinson's disease. Part 1.

    abstract::The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000197103

    authors: Simuni T,Lyons KE,Pahwa R,Hauser RA,Comella C,Elmer L,Weintraub D

    更新日期:2009-01-01 00:00:00

  • Type B monoamine oxidase and neurotoxins.

    abstract::The biochemical process underlying Parkinson's disease is dopamine cell death of the nigrostriatal system. The age-dependent cell death is now proposed to be elicited by the formation of free hydroxy radicals which are formed from hydrogen peroxide, a product of oxidation of dopamine by monoamine oxidase, especially t...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000118535

    authors: Naoi M,Maruyama W

    更新日期:1993-01-01 00:00:00

  • Downregulation of striatal dopamine D2 receptors in advanced Parkinson's disease contributes to the development of motor fluctuation.

    abstract::The purpose of this study was to evaluate the contribution of the postsynaptic mechanism to the development of motor fluctuation in advanced Parkinson's disease (PD). We used 123I-iodobenzamide single-photon emission computed tomography to measure the striatal dopamine D2 receptor densities in early levodopa-naïve PD,...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000047962

    authors: Hwang WJ,Yao WJ,Wey SP,Shen LH,Ting G

    更新日期:2002-01-01 00:00:00

  • Metabolic Disorders in Patients with Central Nervous System Infections: Associations with Neurosyphilis.

    abstract:INTRODUCTION:Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. METHODS:An in-depth ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000503626

    authors: Xiao Y,Chen MJ,Shen X,Lin LR,Liu LL,Yang TC,Niu JJ

    更新日期:2019-01-01 00:00:00

  • Evaluation of the carotid bifurcation by duplex ultrasound, intravenous and intra-arterial digital subtraction angiography.

    abstract::In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116233

    authors: Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

    更新日期:1988-01-01 00:00:00

  • Effects of acyclovir on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia in herpes zoster patients.

    abstract::The effect of oral treatment with acyclovir (ACV) on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia (PHN) was studied in 105 patients with herpes zoster. Forty-seven patients were treated with ACV at a dose of 4 g/day in 5 doses for at least a week; the others did not undergo any kind of...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000117274

    authors: Mondelli M,Romano C,Passero S,Porta PD,Rossi A

    更新日期:1996-01-01 00:00:00

  • The concentration of prealbumin in cerebrospinal fluid (CSF), indicator of CSF circulation disorders.

    abstract::Prealbumin, was determined in serum, lumbar and ventricular cerebrospinal fluid (CSF) and compared with albumin and IgG. The measured concentrations of prealbumin in the CSF indicate that there are two sources of prealbumin: a minor fraction enters the CSF via the blood-cerebrospinal fluid (B-CSF) barrier like albumin...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115544

    authors: Weisner B,Roethig HJ

    更新日期:1983-01-01 00:00:00