Abstract:
:Prealbumin, was determined in serum, lumbar and ventricular cerebrospinal fluid (CSF) and compared with albumin and IgG. The measured concentrations of prealbumin in the CSF indicate that there are two sources of prealbumin: a minor fraction enters the CSF via the blood-cerebrospinal fluid (B-CSF) barrier like albumin, and the major fraction enters the CSF at the ventricles, probably during production of the CSF in the ventricles. The two fractions can be calculated from the CSF concentration of prealbumin, serum prealbumin and the concentration gradient (serum/CSF) of albumin. The B-CSF barrier-independent prealbumin can be used as an indicator of CSF circulation. This was proved by the investigation of several special cases.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Weisner B,Roethig HJdoi
10.1159/000115544subject
Has Abstractpub_date
1983-01-01 00:00:00pages
96-105issue
2eissn
0014-3022issn
1421-9913journal_volume
22pub_type
杂志文章abstract::The cerebral hemispheres show prominent involvement in hypertensive encephalopathy far more frequently than the brainstem. Two patients with severe paroxysmally accelerated hypertension associated with brainstem hyperintensity in T2-weighted magnetic resonance images are presented. Both present hyperintense lesions im...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000100015
更新日期:2007-01-01 00:00:00
abstract::197 cases of patients with CVI, subjected to surgery by carotid endarterectomy, are examined. The results were nearly always good and hence the technique is recommended. Particular interest is attached to the risk connected with carotid clamping, through intraoperative study of CBF with 133Xe, such a risk is practical...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115010
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the influence of psychosocial variables on patients with multiple sclerosis (MS) and the relationship between these variables and the onset of MS. BACKGROUND:The current evidence indicates that many types of psychosocial factors are involved in the development and rel...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000226428
更新日期:2009-01-01 00:00:00
abstract::Early traumatic epilepsy, whose frequency is rather high, especially in children, is usually characterized by focal motor seizures (57%) or by generalized seizures (43%). The association of both running and laughing fits in the same patient on the contrary is quite exceptional, as only three cases have been reported i...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114830
更新日期:1977-01-01 00:00:00
abstract::The efficacy and safety of sumatriptan, a selective 5-HT1-like receptor agonist, were studied in a randomized, double-blind, placebo-controlled, parallel-group, multicentre, multinational clinical trial of 235 patients suffering a moderate to severe migraine attack. Patients were randomized to treat a single migraine ...
journal_title:European neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000116760
更新日期:1991-01-01 00:00:00
abstract::The therapeutic efficacy of Madopar HBS was investigated in 5 patients with advanced parkinsonism. They were under treatment with standard Madopar and suffered from marked fluctuations, mainly end-of-dose akinesia. All patients were abruptly switched from standard Madopar to the HBS formulation. For the first few days...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000116198
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) is commonly characterized by its motor symptoms such as resting tremor, rigidity, bradykinesia and postural instability; however, some of the most debilitating symptoms of this disease are non-motor ones such as dementia and sialorrhea (drooling). Drooling is caused by impaired swall...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000348571
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000215876
更新日期:2009-01-01 00:00:00
abstract::Human slow wave sleep (hSWS) is an important form of sleep that seems to take priority over REM sleep. Although hSWS is commonly thought to be associated with enhanced tissue repair, evidence supporting this view is questioned. For example, total sleep deprivation and loss of hSWS have little or no adverse effect on b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116076
更新日期:1986-01-01 00:00:00
abstract::Autosomal dominant Parkinson's disease in 5 generations of a family living in Sagamihara City is reported. Clinical features of this family did not differ from common PD, however, neuropathological findings were different from PD. In autopsied cases, the loss of melanin-containing cells was mild to moderate, and the n...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000113460
更新日期:1997-01-01 00:00:00
abstract::Missed cerebral aneurysms in CT-negative patients can have serious implications. We set out to determine the usefulness of cerebrospinal fluid (CSF) spectrophotometry and the individual significance of CSF oxyhaemoglobin, bilirubin and methaemoglobin in 463 CT scan-negative patients with suspected subarachnoid haemorr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000082162
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The biological mechanisms by which cerebral aneurysms emerge, enlarge and rupture are not totally understood. In the present study, we analyzed the genome-wide gene expression profile in human intracranial aneurysms using cDNA microarrays. METHODS:Affymetrix HU133 Plus 2.0 microarrays were used to compare g...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000236911
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND/AIMS:We assessed the, hitherto unknown, impact of intravenous methylprednisolone (ivMP) pulses during relapses of multiple sclerosis (MS) on the kinetics of anti-interferon-beta neutralizing antibodies (Nabs) and binding antibodies (Babs). METHODS:Babs (ELISA) and Nabs (antiviral cytopathic effect assay) ti...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000444319
更新日期:2016-01-01 00:00:00
abstract::Our knowledge about pathophysiology of intracerebral hemorrhage (ICH) mainly originates from preclinical models of ICH. In this study, cerebral ultrastructure surrounding hematoma and its correlation with clinical severity were investigated in ICH patients. Thirty patients with basal ganglia hemorrhage and 6 control s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000434631
更新日期:2015-01-01 00:00:00
abstract::The purpose of this study was to evaluate the contribution of the postsynaptic mechanism to the development of motor fluctuation in advanced Parkinson's disease (PD). We used 123I-iodobenzamide single-photon emission computed tomography to measure the striatal dopamine D2 receptor densities in early levodopa-naïve PD,...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000047962
更新日期:2002-01-01 00:00:00
abstract::The Uhthoff symptom, a transient impairment of visual function after exercise, is demonstrated in 2 multiple sclerosis patients. Following exercise, impairment of visual function, as documented most clearly by the testing of contrast sensitivity, was less obvious after body surface cooling and after treatment with ora...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116830
更新日期:1992-01-01 00:00:00
abstract::To elucidate the clinical characteristics of aged patients with Becker muscular dystrophy (BMD), 4 patients with this disease who were over 50 years were examined. The ages at onset in all patients were later than 30 years. All were proven to have a deletion around exons 45-55 of the Duchenne muscular dystrophy (DMD) ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008089
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Focal embouchure dystonia (FED) is a type of task-specific dystonia affecting wind instrument players, and it frequently ends their professional careers. The results of the treatments of FED in the reported literature are disappointing. OBJECTIVE:We report 3 patients with FED who were brass instrument playe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000329578
更新日期:2011-01-01 00:00:00
abstract::A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116120
更新日期:1987-01-01 00:00:00
abstract::A 48-year-old woman was referred from Zaire with suspected rabies encephalitis. Survival was 34 days after the onset of symptoms and the diagnosis of rabies was ultimately proven after brain autopsy. Serial neurophysiological investigations, including EEG and multimodality evoked potentials and radiological examinatio...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116939
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000285165
更新日期:2010-01-01 00:00:00
abstract::Superior orbital fissure syndrome is a symptomatologic complex, consisting of retroorbital pain, paralysis of extraocular muscles, impairment of first trigeminal branches and frequent involvement of the optic nerve. From a review of 130 published cases including two personal observations, it appears that the clinical ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114876
更新日期:1977-01-01 00:00:00
abstract::Median nerve somatosensory evoked potentials (SEPs) and jerk-locked EEG back-averaging (JLA) were performed in 2 patients with left-hand myoclonus. Both SEPs were characterized by a normal parietal N20 and an enhanced N27-P27 fronto-parietal complex, but the giant central N40 described by most authors was only observe...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000119509
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000052116
更新日期:2001-01-01 00:00:00
abstract::In the last 2 years we have systematically treated 31 sleep apnea patients with 25-50 mg imipramine HCl given 30 min before bedtime. Imipramine treatment was attempted for nonoverweight patients with negative ear, nose and throat (ENT) findings and for patients who had not responded to weight reduction or ENT surgery ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115991
更新日期:1986-01-01 00:00:00
abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116350
更新日期:1987-01-01 00:00:00
abstract::This study investigated the maximum number of collaterals that can be maintained by 1 axon during regeneration of rat peripheral nerve. The tibial nerve was transected, the proximal residual, with its variable number of axons, was fixed to the distal stump and served as the donor nerve. The number of myelinated axons ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000102161
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND AND STUDY PURPOSE:Autonomic nervous system dysfunction is a common complication of acute cerebrovascular disorders. The aim of this study was to investigate a possible location-dependent difference in cardio-autonomic function in patients with ischaemic stroke. PATIENTS AND METHODS:Sympathetic function was ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000070856
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Mor...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000456003
更新日期:2017-01-01 00:00:00
abstract::We examined 29 patients with chronic progressive ganglionopathy of different etiology. Neurophysiological abnormalities were dominated by a widespread decrease in sensory nerve action potential amplitudes, which involved both upper and lower limb nerves, even in patients with asymmetrical or patchy clinical presentati...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000073055
更新日期:2003-01-01 00:00:00