Effect of hypocapnia on cerebral oxygen metabolism and blood flow in ischemic cerebrovascular disorders.

abstract：OBJECTIVE:To assess the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) in patients with clinically isolated syndrome (CIS). METHODS:130 European CIS patients and 60 relatives completed the MSNQ. RESULTS:The mean (SD) MSNQ score for CIS patients was 15.5 (10.8) and for their informants 11.3 (9.6). Neither ...

journal_title：European neurology

authors： Langdon DW,Benedict RH,Wicklein EM,Beckmann K,Fredrikson S

更新日期：2013-01-01 00:00:00

abstract：:Dementia is one of the most common organic mental syndromes, usually caused by Alzheimer's disease (AD) or vascular dementia (VD) or both. Regarding AD we review the state or the art of the cholinergic approach and discuss some future options regarding preventive and nonsymptomatic strategies. Therapy for VD will cons...

journal_title：European neurology

authors： Scheltens P,van Gool WA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Antioxidant enzymes like copper/zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular diseases and acute stroke. We investigated the differences of antioxi...

journal_title：European neurology

authors： Zimmermann C,Winnefeld K,Streck S,Roskos M,Haberl RL

更新日期：2004-01-01 00:00:00

abstract：:Three patients with cerebral tumor involving diencephalic midline structures (2 malignant gliomas, 1 craniopharyngioma) and no metabolic abnormalities developed disorientation in time and place or coma with triphasic waves (TW) seen on electroencephalograms. Serial EEG recordings showed persistence or disappearance of...

journal_title：European neurology

authors： Aguglia U,Gambardella A,Oliveri RL,Lavano A,Camerlingo R,Quattrone A

更新日期：1990-01-01 00:00:00

abstract：:The effect of thoracic duct lymph drainage (5-34 days) in 12 patients with myasthenia gravis on muscular function has been followed for 5-43 months. Among the results obtained were: (1) During the drainage the myasthenic symptoms decreased markedly after 1-4 days and remained so during the drainage. (2) The doses of c...

journal_title：European neurology

authors： Bergström K,Franksson C,Matell G,Nilsson BY,Persson A,von Reis G,Stensman R

更新日期：1975-01-01 00:00:00

abstract：:Oxidative stress and generation of reactive oxygen species are believed to be implicated in Parkinson's disease (PD). Erythrocyte activity of superoxide dismutase (SOD) and catalase, the blood glutathione system, and plasma levels of thiobarbituric-acid-reactive substances (TBARS) were measured in 80 PD patients. Thes...

journal_title：European neurology

authors： Younes-Mhenni S,Frih-Ayed M,Kerkeni A,Bost M,Chazot G

更新日期：2007-01-01 00:00:00

abstract：:The authors themselves studied 26 patients. The EEGs were classified in terms of increasing severity in 5 categories. Incorporating over 400 cases from the literature, the authors correlated the initial EEG findings with the clinical outcome following cardiac arrest. Grade I EEG findings (normal alpha with theta-delta...

journal_title：European neurology

authors： Scollo-Lavizzari G,Bassetti C

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke's encephalopathy with cortical abnormalities (WEc). METHODS:We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. RESULTS:Besides the cla...

journal_title：European neurology

authors： Sakurai K,Sasaki S,Hara M,Yamawaki T,Shibamoto Y

更新日期：2009-01-01 00:00:00

abstract：:L-Dopa pioneered the symptomatic therapy of Parkinson's disease. While this treatment proved effective in the treatment of parkinsonian akinesia, rigidity and tremor, prolonged L-dopa treatment was often noted to result in dyskinesia, psychosis and 'on-off' phenomena. This increasing disability of L-Dopa-treated parki...

journal_title：European neurology

authors： Kuno S

更新日期：1994-01-01 00:00:00

abstract：:To quantitate embolic risk we studied a retrospective series of 61 patients with strictly defined bacterial endocarditis. Eighteen patients had neurological complications attributable to cerebral embolism. Seventeen embolic episodes occurred prior to antibiotic treatment and 8 episodes after its commencement. The rate...

journal_title：European neurology

authors： Paschalis C,Pugsley W,John R,Harrison MJ

更新日期：1990-01-01 00:00:00

abstract：:Tardive dyskinesia (TD) induced by antipsychotic drugs represents a great concern for patients and psychiatrists. Considering its pathophysiological mechanisms, there exists a convergence towards the development of postsynaptic dopaminergic hypersensitivity as a possible cause of TD. Hypersensitivity following recepto...

journal_title：European neurology

authors： Mouret J,Khomais M,Lemoine P,Sebert P

更新日期：1991-01-01 00:00:00

abstract：:Don Quixote de la Mancha, which is considered one of the most important and influential works of Western modern prose, contains many references of interest for almost all of the medical specialties. In this regard, numerous references to neurology can be found in Cervantes' immortal work. In this study, we aimed to re...

journal_title：European neurology

authors： Palma JA,Palma F

更新日期：2012-01-01 00:00:00

abstract：:The pathogenesis of primary degenerative dementia is still unknown and current therapeutic approaches can aim only at ameliorating some of the symptoms associated with this brain disease. At present, most approaches, attempt to correct a cholinergic deficit. Although the therapeutic benefits obtained so far with curre...

journal_title：European neurology

authors： Markstein R

更新日期：1989-01-01 00:00:00

abstract：:The serum concentration of S-100B is reported to reflect the severity of brain damage. The purpose of this study was to determine whether elevated serum S-100B concentrations were related to neuropsychological test performance of patients in the subacute phase of recovery from mild traumatic brain injury (TBI). S-100B...

journal_title：European neurology

authors： Stapert S,de Kruijk J,Houx P,Menheere P,Twijnstra A,Jolles J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Dizziness and vertigo are frequent complaints of outpatients in the neurological department. Our objective was to explore the epidemiological category and clinical features of patients with dizziness or vertigo in the neurological outpatient department of a tertiary hospital. METHODS:We consecutively recrui...

journal_title：European neurology

authors： Pan Q,Zhang Y,Long T,He W,Zhang S,Fan Y,Zhou J

更新日期：2018-01-01 00:00:00

abstract：:A 20-year-old woman with Kearns-Sayre syndrome (KSS) suddenly experienced two episodes of diabetic coma. She was studied to determine whether diabetes mellitus (DM) resulted from insulin resistance or from an insulin secretion abnormality, using the euglycemic glucose clamp technique and the glucagon tolerance test. S...

journal_title：European neurology

authors： Tanabe Y,Miyamoto S,Kinoshita Y,Yamada K,Sasaki N,Makino E,Nakajima H

更新日期：1988-01-01 00:00:00

abstract：:Here we review a total of 17 patients, including 4 of our own, with young-adult-onset arteriosclerotic leukoencephalopathy, alopecia and lumbago without hypertension. All were Japanese and the illness seemed to be transmitted in an autosomal recessive fashion. The male to female ratio was 7.5:1. The age of onset usual...

journal_title：European neurology

authors： Fukutake T,Hirayama K

更新日期：1995-01-01 00:00:00

abstract：:Changes in the maximal rate of some cerebral enzymatic activities related to 400ene transduction and neurotransmission (lactate dehydrogenase; citrate synthase and malate dehydrogenase; total NADH-cytochrome c reductase and cytochrome oxidase; glutamate dehydrogenase; acetylcholine esterase) were assayed both in the c...

journal_title：European neurology

authors： Villa RF

更新日期：1981-01-01 00:00:00

abstract：:The lupus anticoagulant, an immunoglobulin of the IgG or IgM class, is one of a group of antiphospholipid antibodies. Although an anticoagulant in vitro, its action in vivo is that of a procoagulant. This procoagulant activity may involve many organ systems including the nervous system. Thus far cerebral thrombosis, s...

journal_title：European neurology

authors： Englert H,Derue G,Hughes GR

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:Cerebral arteriovenous malformations (AVMs) harbor a network of abnormal vasculatures, namely the nidus between arterial and venous components. The pressure gradient between these two components results in abnormal high-velocity arteriovenous shunts flowing through the nidus and alternate intracranial hemody...

journal_title：European neurology

authors： Chuang YM,Guo W,Lin CP

更新日期：2010-01-01 00:00:00

abstract：:In this open study patients with advanced Parkinson's disease, who experienced pronounced fluctuations in symptoms while on standard L-dopa, were switched from Madopar/Sinemet to Madopar HBS. The dosage was adjusted until optimal response was obtained. The effect was unsatisfactory in 4 cases and side effects interven...

journal_title：European neurology

authors： Jensen NO,Dupont E,Hansen E,Mikkelsen B,Mikkelsen BO

更新日期：1987-01-01 00:00:00

abstract：:A critical analysis of cases of systemic lupus erythematosus (SLE) and chorea is presented. Choreatic movements occurred early in the course of the disease in most cases; the duration varied from several days to 3 years. No sex predominance was found and no relationship could be demonstrated between chorea and other n...

journal_title：European neurology

authors： Bruyn GW,Padberg G

更新日期：1984-01-01 00:00:00

abstract：:To examine the possible influence of the blood-CSF barrier function on mathematical formulas for estimating intrathecal IgG production (IgG index, Tourtellotte's formula [TOURT], Schuller and Sagar's formula [Schull], and Reiber and Felgenhauer's formula [IgG(loc)]), we analysed serum and CSF samples from 105 healthy ...

journal_title：European neurology

authors： Blennow K,Fredman P,Wallin A,Gottfries CG,Skoog I,Wikkelsö C,Svennerholm L

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Profound cellular and biochemical remodeling processes occur in the brain following an ischemic stroke, raising the possibility that we may be able to promote neurological recovery by harnessing the brain's endogenous recovery processes with pharmacological or cell-based therapies. There is a compelling body...

journal_title：European neurology

authors： Hermann DM,Chopp M

更新日期：2014-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu H,Chang JG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The association between edentulism and cerebral small vessel disease is controversial. We aimed to assess this relationship in community-dwelling older adults living in rural Ecuador. METHODS:MRI was performed in 311 (81%) of 385 individuals ≥60 years enrolled in the Atahualpa Project. Participants were cla...

journal_title：European neurology

authors： Del Brutto OH,Mera RM,Zambrano M

更新日期：2016-01-01 00:00:00

abstract：:This study aimed at examining correlations between quantitative REM sleep EEG, regional cerebral blood flow measured by single photon emission computerized tomography (SPECT) and global cognitive functioning in nine patients with mild to moderate Alzheimer's disease. REM sleep EEG was not correlated with SPECT measure...

journal_title：European neurology

authors： Montplaisir J,Petit D,McNamara D,Gauthier S

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Several treatments are available to treat the immune-mediated chronic inflammatory demyelinating polyneuropathy (CIDP). Among these treatments, intravenous immunoglobulins, corticosteroids and plasma exchanges are validated and widely used. A few immunosuppressive drugs have been tried, but they had little e...

journal_title：European neurology

authors： Vallat JM,Mathis S,Ghorab K,Milor MA,Richard L,Magy L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Thalamic lesion due to deep cerebral venous thrombosis (DCVT) is an uncommon cause of stroke. Until now, only a few case reports have been published. The aim of the study is to report the clinical and radiological findings of thalamic lesion with DCVT. METHODS:We reviewed our computerized stroke database of...

journal_title：European neurology

authors： Caplan LR,Wang Q

更新日期：2015-01-01 00:00:00

abstract：:Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...

journal_title：European neurology

authors： Reichmann H,Degoul F,Gold R,Meurers B,Ketelsen UP,Hartmann J,Marsac C,Lestienne P

更新日期：1991-01-01 00:00:00