Reports of patients and relatives from the CogniCIS study about cognition in clinically isolated syndrome: what are our patients telling us?

abstract：:In 128 patients with multiple sclerosis (MS) and 204 blood donors (control persons) the in vitro activation of 'Ficoll-purified' peripheral blood T lymphocytes was measured using the 3H-thymidine incorporation rate without (spontaneous proliferation) and with mitogen addition (concanavalin A, phytohemagglutinin). Mito...

journal_title：European neurology

authors： Trenn G,Kreuzfelder E,Hierholzer E,Scheiermann N,Bauer HJ,Bushart W

更新日期：1988-01-01 00:00:00

abstract：:A 24-year-old man presented with dystonia, dementia, amyotrophy, choreoathetosis, and ataxia. Partial hexosaminidase A deficiency was documented in serum and leukocytes and confirmed by rectal biopsy with ganglion cells containing membranous cytoplasmic bodies. A brief review of the literature reveals that tremor, dys...

journal_title：European neurology

authors： Oates CE,Bosch EP,Hart MN

更新日期：1986-01-01 00:00:00

abstract：AIMS:To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy in a European country. METHODS:A cross-sectional questionnaire survey. The questionnaire was distributed by the medical staff in different outpatient waiting rooms (obstetrics and gynecology department of the univ...

journal_title：European neurology

authors： Neau JP,Porcheron A,Mathis S,Julian A,Meurice JC,Paquereau J,Godeneche G,Ciron J,Bouche G

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to...

journal_title：European neurology

authors： Constantinescu I,Korff CM,Vulliemoz S,Picard F,Seeck M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Newer Scandinavian data on intracerebral hemorrhage (ICH) are scarce. We aimed at providing updated community-based data on the incidence, characteristics and outcome of ICH leading to hospitalization in the southernmost region in Norway. METHODS:We analyzed data from all consecutive patients hospitali...

journal_title：European neurology

authors： Tveiten A,Ljøstad U,Mygland A,Thomassen L,Pripp AH,Naess H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...

journal_title：European neurology

authors： Hao Z,Wu B,Lin S,Kong FY,Tao WD,Wang DR,Liu M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Statins inhibit the production of 2,3-dimethoxy,5-methyl,6-polyisoprene parabenzoquinone also known as ubiquinone or coenzyme Q10 (CoQ10), which is required for mitochondrial electron transport. Idiopathic or primary CoQ10 deficiencies have been known to cause mitochondrial encephalomyopathy. METHODS:We pre...

journal_title：European neurology

authors： Thomas JE,Lee N,Thompson PD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Most of the previously described pathogenic mutations in desmin are located in highly conserved α-helical domains that play an important role in intermediate filament assembly. The role of the C-terminus non-α-helical 'tail' domain is much less investigated and until recently mutations in this domain have be...

journal_title：European neurology

authors： Maddison P,Damian MS,Sewry C,McGorrian C,Winer JB,Odgerel Z,Shatunov A,Lee HS,Goldfarb LG

更新日期：2012-01-01 00:00:00

abstract：:The effects of biologically active light (BL) on subjective and objective quality of sleep and awakening, as well as circadian rhythms in cortisol, temperature and well-being were studied in 10 hospitalized normal female volunteers as compared with partial sleep deprivation (PSD). After 2 adaption days, three 24-hour ...

journal_title：European neurology

authors： Saletu B,Dietzel M,Lesch OM,Musalek M,Walter H,Grünberger J

更新日期：1986-01-01 00:00:00

abstract：:Dopamine uptake sites, labelled by 3 nM [3H]GBR 12935, were reduced by 28-34% in post-mortem Parkinson's diseased striata (n = 22) compared to control striata (n = 28). There was no significant difference between post-mortem striata from schizophrenics (n = 16) and controls. Both dopamine D1 and D2 receptors are consi...

journal_title：European neurology

authors： Pearce RK,Seeman P,Jellinger K,Tourtellotte WW

更新日期：1990-01-01 00:00:00

abstract：:Temporal arteritis (TA) is a vasculitis involving mainly cranial branches of the aorta that can lead to ischemic complications such as amaurosis or ischemic stroke. Increment in the platelet count has been described in the acute period of the disease. We studied retrospectively the platelet count in patients with TA, ...

journal_title：European neurology

authors： Gonzalez-Alegre P,Ruiz-Lopez AD,Abarca-Costalago M,Gonzalez-Santos P

更新日期：2001-01-01 00:00:00

abstract：:This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later. ...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:Electrophysiological findings in 10 patients with polyneuropathy and nonmalignant IgMk plasma cell dyscrasia are reported. The amplitude of sensory action potentials and maximum conduction velocity along the sural and median nerves are related to the structural changes found at the biopsy and to the immunologic result...

journal_title：European neurology

authors： Galassi G,Nemni R

更新日期：1986-01-01 00:00:00

abstract：:Of 150 new cases of nasopharyngeal carcinoma diagnosed in Israel during a 9-year period (nationwide study 1960--1968), 74 patients developed neurological complications. In 92% of the cases, neurologic deficits were confined exclusively to cranial nerves. The majority of these patients presented general symptoms of dis...

journal_title：European neurology

authors： Turgman J,Braham J,Modan B,Goldhammer Y

更新日期：1978-01-01 00:00:00

abstract：:Henri Duret (1849-1921) was a surgeon whose training started in the laboratory of Jean-Martin Charcot and Alfred Vulpian at La Salpêtrière in 1874. Using injections of colored gelatine, Duret was the first to describe the distribution of supply arteries in the brainstem and then in the cortex. His descriptions correla...

journal_title：European neurology

authors： Walusinski O,Courrivaud P

更新日期：2014-01-01 00:00:00

abstract：:In a prospective study we evaluated myoglobin (MG) and serum creatine kinase (CK) levels in two groups of subjects different in age and carrier status. CK and MG values were significantly lower in the older group. Whereas both parameters fully coincided in the younger group, CK was detected in a higher number of carri...

journal_title：European neurology

authors： Sabria-Leal M,Gimeno-Leal JM,Paret-Masana A,Rey-Joly Barroso C

更新日期：1986-01-01 00:00:00

abstract：:Many gadolinium-enhanced magnetic resonance imaging (MRI) studies focusing on the anatomy and pathology of the 7th cranial nerve have already been published. However, only scattered cases of herpes zoster oticus (HZO) have been described and only the MRI appearance of the soft temporal bone structures has been reporte...

journal_title：European neurology

authors： Berrettini S,Bianchi MC,Segnini G,Sellari-Franceschini S,Bruschini P,Montanaro D

更新日期：1998-01-01 00:00:00

abstract：:Since the advent of whole-body CT scanning in 1974, many studies have been made in its application to all parts of the body. One of the most fruitful areas has been CT of the spinal cord. The only limitation appears to be the technique used; there is no substitute for a good technique. We shall first review standard C...

journal_title：European neurology

authors： Ledley RS

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:ANO10 mutations have recently been reported in autosomal recessive cerebellar ataxia type 3 (ARCA3). The objective of this study was to describe the phenotype of 2 siblings with compound heterozygous ANO10 mutations and progressive cerebellar ataxia, epilepsy, and cognitive impairment. A porencephalic cyst w...

journal_title：European neurology

authors： Chamard L,Sylvestre G,Koenig M,Magnin E

更新日期：2016-01-01 00:00:00

abstract：:Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...

journal_title：European neurology

authors： Kaido M,Fujimura H,Ono A,Toyooka K,Yoshikawa H,Nishimura T,Ozaki K,Narama I,Kuwajima M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Focal embouchure dystonia (FED) is a type of task-specific dystonia affecting wind instrument players, and it frequently ends their professional careers. The results of the treatments of FED in the reported literature are disappointing. OBJECTIVE:We report 3 patients with FED who were brass instrument playe...

journal_title：European neurology

authors： Satoh M,Narita M,Tomimoto H

更新日期：2011-01-01 00:00:00

abstract：:Transient ischemic attacks (TIAs) are warning episodes predicting that such patients are at high risk for stroke which potentially could be life-threatening or leave an individual with substantial disability. TIAs result from large or small vessel disease, cardiogenic embolic events and hematological abnormalities. Th...

journal_title：European neurology

authors： Anwer UE

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Large cavitary lesions are not typical for multiple sclerosis (MS). Cavitary white matter changes may be seen in megalencephalic leukoencephalopathy with subcortical cysts, Alexander disease, mitochondrial leukoencephalopathies, vanishing white matter disease, leukoencephalopathy with calcifications and cyst...

journal_title：European neurology

authors： Renard D,Brochet B,Vukusic S,Edan G,Deburghgraeve V,Goizet C,Dupuy D,Touze E,Deschamps R,Zephyr H,Creange A,Castelnovo G,Boespflug-Tanguy O,Labauge P

更新日期：2012-01-01 00:00:00

abstract：:70 cases of multiple sclerosis were seen at the Department of Neurology of the Capital Hospital in 1949--1977. There were 25 males and 45 females averaging 30.6 years of age. The most frequent sites of the lesions based on the clinical symptomatology were the spinal cord and optic nerve, the cerebellum was much less f...

journal_title：European neurology

authors： Zhao BX,Liu XQ,Guo YP,Yang YC,Huang HF

更新日期：1981-01-01 00:00:00

abstract：:The biochemical process underlying Parkinson's disease is dopamine cell death of the nigrostriatal system. The age-dependent cell death is now proposed to be elicited by the formation of free hydroxy radicals which are formed from hydrogen peroxide, a product of oxidation of dopamine by monoamine oxidase, especially t...

journal_title：European neurology

authors： Naoi M,Maruyama W

更新日期：1993-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu H,Chang JG

更新日期：1999-01-01 00:00:00

abstract：:18F-Dopa positron emission tomography (PET) provides a sensitive means of quantitating the loss of nigrostriatal dopaminergic fibres in Parkinson's disease and so can be used to diagnose its presence and to objectively follow the rate of disease progression. It can also be used, in principle, to determine the efficacy...

journal_title：European neurology

authors： Brooks DJ

更新日期：1997-01-01 00:00:00

abstract：:We report a 52-year-old man with idiopathic thrombocytopenic purpura accompanying acute oculomotor nerve palsy. At autopsy, intraneural hemorrhage was found in the cavernous portion of the oculomotor nerve. Intraneural bleeding as well as extraneural compression by hematoma formation should be considered as a cause of...

journal_title：European neurology

authors： Miyao S,Takano A,Teramoto J,Fujitake S,Hashizume Y

更新日期：1993-01-01 00:00:00

abstract：:Clinicopathological data of a woman with a 3-year course of concurrent amyotrophic lateral sclerosis and dementia are presented. Dementia had occurred at time of onset of motor disturbances and presented as typical frontal lobe dementia. Pathology confirmed motor neuron disease of amyotrophic lateral sclerosis and fro...

journal_title：European neurology

authors： Müller M,Vieregge P,Reusche E,Ogomori K

更新日期：1993-01-01 00:00:00

abstract：:The aim of this study was to assess the impact of cardiac autonomic derangement on gender-associated functional outcome of patients with subacute ischemic stroke undergoing a hospital-based rehabilitation program. The study population included 126 consecutive first-ever stroke survivors (mean age 59.7 +/- 11.6 years)....

journal_title：European neurology

authors： Bassi A,Colivicchi F,Santini M,Caltagirone C

更新日期：2010-01-01 00:00:00