Abstract:
:Clinicopathological data of a woman with a 3-year course of concurrent amyotrophic lateral sclerosis and dementia are presented. Dementia had occurred at time of onset of motor disturbances and presented as typical frontal lobe dementia. Pathology confirmed motor neuron disease of amyotrophic lateral sclerosis and frontal lobe atrophy. Multiple senile plaques were distributed cortically and in the hippocampus, where diffuse spread of neurofibrillary tangles was seen. Hence, this Alzheimer's dementia in a patient with sporadic amyotrophic lateral raises the question of a possible association between the two conditions.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Müller M,Vieregge P,Reusche E,Ogomori Kdoi
10.1159/000116962subject
Has Abstractpub_date
1993-01-01 00:00:00pages
320-4issue
4eissn
0014-3022issn
1421-9913journal_volume
33pub_type
杂志文章,评审abstract::T lymphocytes were determined according to their ability to form rosettes with sheep erythrocytes, in cerebrospinal fluid (CSF) from 120 patients, and in peripheral blood from 59 patients. Normal CSF contained 74.9 +/- 9.6% T lymphocytes. Increased T lymphocyte percentage was found in CSF from patients with active mul...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115074
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:The K variant of butyrylcholinesterase (BCHE-K) exhibits a reduced acetylcholine-hydrolyzing capacity; so the clinical response to rivastigmine may differ in Alzheimer's disease (AD) patients with the BCHE-K gene. OBJECTIVE:To investigate the clinical response to rivastigmine transdermal patch monotherapy o...
journal_title:European neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000366198
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Several testing options are available to detect asymptomatic coronary artery disease (CAD). Dobutamine stress echocardiography (DSE) has been reported to increase the sensitivity and specificity of stress testing to detect CAD. Most studies concerned patients with known or suspected CAD who have a high prete...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000096488
更新日期:2006-01-01 00:00:00
abstract::A woman who had spontaneous pain, hyperpathia and wasting of her left hand due to a subcortical lesion in the right parietal lobe is reported. The presentation and evaluation of this most unusual case are discussed. ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115753
更新日期:1985-01-01 00:00:00
abstract::A young man presented with myokymias, cramp-like difficulty in muscle relaxation and peroneal atrophy. EMG studies revealed continuous muscle activity (CMA) manifested as grouped potentials and high frequency discharges. Sensory nerve conduction studies and sural nerve biopsy gave normal results, and he was thought to...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116667
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000318171
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The history of Sayk's cell sedimentation chamber is examined and reviewed in the context of clinically utilizable cerebrospinal fluid (CSF) cytology. METHODS:A review of the literature was undertaken in PubMed and Google Scholar to search for primary and secondary sources on the history of CSF diagnosis. Mor...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000456003
更新日期:2017-01-01 00:00:00
abstract::Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008187
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to ascertain the clinical manifestations of granulomatosis with polyangiitis (Wegener's) (GPA) with the involvement of the peripheral nervous system (PNS) and central nervous system (CNS). SUMMARY:All neurologic inpatients in a hospital over a 12-year period were reviewed. Nine pat...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000375492
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Central pontine myelinolysis (CPM)/extrapontine myelinolysis (EPM) is one of the most serious neurological complications that can occur after orthotopic liver transplantation (OLT). We analyzed the risk factors for CPM/EPM in OLT patients. METHODS:We retrospectively reviewed the records of 1,247 patients wh...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000242426
更新日期:2009-01-01 00:00:00
abstract::Calcium ions play a major role in the regulation of cell functions. Minor alterations of the cellular calcium ion homeostasis lead to major functional aberrations. Alterations of the calcium homeostasis occur under conditions of hypoxia, the major cause being an extracellular increase of potassium ions which gate volt...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116059
更新日期:1986-01-01 00:00:00
abstract::The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000445540
更新日期:2016-01-01 00:00:00
abstract::Sir William Gull coined the name 'anorexia nervosa'. Examples of self-starvation appeared in the Hellenistic era. Holy anorexics abused their bodies, rejected marriage and sought religious asylum where many perished and became saints. The condition then paled into obscurity until the 19th century. Louis-Victor Marce (...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000082033
更新日期:2004-01-01 00:00:00
abstract::A case of thoracic hematomyelia secondary to anticoagulant therapy is presented. Clinical features, similar to 2 other previously reported cases, are discussed. A high index of suspicion may lead to a quick diagnostic procedure and successful decompressive surgery. ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116804
更新日期:1992-01-01 00:00:00
abstract::Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000007915
更新日期:1998-01-01 00:00:00
abstract::Two cases of malignant tumours of the nerve sheaths are reported. In the first patient, who had von Recklinghausen's disease, light- and electron-microscopic investigations showed an undifferentiated mesenchymal tumour of the radial nerve with the property of producing collagen fibres, an aspect characteristic of sarc...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114873
更新日期:1977-01-01 00:00:00
abstract:PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000050752
更新日期:2001-01-01 00:00:00
abstract::The blink reflex and its equivalent glabella tap reflex are behavioural motor responses normally found in neonates and in the physiological startle reflex. Historically, it was described by Overend in 1896 and soon afterwards by McCarthy and by Bekhterev who disputed its origins. Kugelberg in 1952 recorded the early-l...
journal_title:European neurology
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000114053
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Thalamic lesion due to deep cerebral venous thrombosis (DCVT) is an uncommon cause of stroke. Until now, only a few case reports have been published. The aim of the study is to report the clinical and radiological findings of thalamic lesion with DCVT. METHODS:We reviewed our computerized stroke database of...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000439167
更新日期:2015-01-01 00:00:00
abstract::We report on management strategies and clinical outcomes in 4 cases of acute symptomatic congestive intracranial hypertension associated with cerebral arteriovenous malformations (AVMs). Congestion resulted from high-volume shunts exhausting the drainage capacity of the cerebral venous system in 3 patients, and from s...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000109263
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Antioxidant enzymes like copper/zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular diseases and acute stroke. We investigated the differences of antioxi...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000077662
更新日期:2004-01-01 00:00:00
abstract::The clinical and biochemical data on 13 patients with Batten's syndrome are described. Clinically the disease was characterized by progressive maental and somatic deterioration. Initially, vision loss was found between the ages 4 and 8 years. This was associated with 1 or 2 years of normal school attendance followed b...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114834
更新日期:1977-01-01 00:00:00
abstract::Embolism from the aneurysmal sac is a rare but possible manifestation of intracranial aneurysm; thrombus formation is probably related to the combined action of turbulent flow and a 'stagnant zone'. Three cases are presented: 2 with giant aneurysms (1 internal carotid and 1 sylvian) and 1 with a large aneurysm of the ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116824
更新日期:1992-01-01 00:00:00
abstract::We report a 17-year-old patient who presented a chronic relapsing sensorimotor demyelinating neuropathy with 6 relapses over a 7-year period, preceding by 4 years the diagnosis of a multicentric angiofollicular lymph node hyperplasia. A role for Epstein-Barr virus (EBV) as a trigger of the neuropathy may be suggested ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117156
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the diagnostic yield of nerve biopsy in patients with peripheral neuropathy of undetermined cause despite extensive diagnostic workup. METHODS:From November 2001 through January 2004, 38 patients underwent nerve biopsy because of unclassified neuropathy. RESULTS:The etiology of the neuropathies...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000098057
更新日期:2007-01-01 00:00:00
abstract::Morphological findings of 3 cases of Kaeser's scapulo-peroneal muscular atrophy are described. 1 of them is the first complete autopsy report on this disease. While the number of motor neurons in the spinal cord was grossly normal, the neuropil of the anterior horn exhibited axonal swellings, accumulations of possibly...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114899
更新日期:1977-01-01 00:00:00
abstract::Two cases of lithium neurotoxic effects are reported. Both cases are expressed by choreoathetotic movements and in both of them intoxication was caused by combined drug therapy. In our opinion caution is advised when lithium is administered in combination with drugs, especially in elderly patients. ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116044
更新日期:1986-01-01 00:00:00
abstract::To investigate the association between APOE-epsilon4 allele and memory phenotype in the preclinical stage of Alzheimer's disease (AD). We compared an extensive preclinical memory profile at the baseline evaluation of 2 AD genotype groups: APOE-epsilon4 allele carriers and patients with APOE-epsilon3 homozygosity. Base...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000078486
更新日期:2004-01-01 00:00:00
abstract::Although multifocal motor neuropathy (MMN) is now recognized as a distinct, albeit rare, neurological condition, the path to its recognition was long and winding. This article provides an insight into the medical history of MMN "patient zero" and the first scientific publication that led to the recognition of MMN by t...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000511732
更新日期:2020-11-11 00:00:00
abstract::Familial cases of HTLV-I-associated myelopathy (HAM) and adult T-cell leukemia (ATL), developing in a daughter and father, respectively, are reported. The coexistence of both diseases in a family has not been reported before. This supports the recent findings that ATL and HAM may be brought about by an identical virus...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116373
更新日期:1989-01-01 00:00:00