Cognitive, but not mood dysfunction develops in multiple sclerosis during 7 years of follow-up.

abstract：OBJECTIVES:We attempted to investigate changes of the pedunculopontine nucleus (PPN) according to walking ability in chronic stroke patients, using diffusion tensor imaging (DTI). METHODS:55 consecutive chronic stroke patients who were not able to walk due to injury of the corticospinal tract (CST) at stroke onset and...

journal_title：European neurology

authors： Yeo SS,Ahn SH,Choi BY,Chang CH,Lee J,Jang SH

更新日期：2011-01-01 00:00:00

abstract：:We examined interleukin-2 (IL-2) production by phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMs) from 75 untreated myasthenia gravis (MG) patients and 48 control patients. Patients with MG consisted of those with elevated PBM IL-2 production (>1,250 pg/ml; mean + 2SD of the controls) (n = 2...

journal_title：European neurology

authors： Utsugisawa K,Nagane Y,Obara D,Kondoh R,Yonezawa H,Tohgi H

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The K variant of butyrylcholinesterase (BCHE-K) exhibits a reduced acetylcholine-hydrolyzing capacity; so the clinical response to rivastigmine may differ in Alzheimer's disease (AD) patients with the BCHE-K gene. OBJECTIVE:To investigate the clinical response to rivastigmine transdermal patch monotherapy o...

journal_title：European neurology

authors： Han HJ,Kwon JC,Kim JE,Kim SG,Park JM,Park KW,Park KC,Park KH,Moon SY,Seo SW,Choi SH,Cho SJ

更新日期：2015-01-01 00:00:00

abstract：:The frontal lobe is the largest lobe of the brain, and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas. This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkabl...

journal_title：European neurology

authors： Bogousslavsky J

更新日期：1994-01-01 00:00:00

abstract：:Camptocormia (bent spine syndrome, cyphose hystérique) is an abnormality characterized by severe forward flexion of the thoracolumbar spine which typically increases during walking or standing and completely disappears in supine position. Camptocormia can be due to central nervous system diseases, such as Parkinson's ...

journal_title：European neurology

authors： Finsterer J,Strobl W

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Albuminuria and carotid atherosclerosis are predictors of cardiovascular disease and potential predictors of cognitive decline. Our aim was to study whether albuminuria was an early predictor of cognitive function independent of carotid atherosclerosis in a general population. METHODS:The study populat...

journal_title：European neurology

authors： Rogne SO,Solbu MD,Arntzen KA,Herder M,Mathiesen EB,Schirmer H

更新日期：2013-01-01 00:00:00

abstract：:Synaesthesia is the intriguing, involuntary experience of feeling one sensation in response to a different sensory stimulus. Recognised since described in 1890 by John Locke and clarified by Galton in the 1880s, it has been analysed in the last 50 years. Grapheme-colour synaesthesia is the commonest form, but many oth...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:The authors describe a case where a parkinsonian symptomatology is associated with pneumoencephalographic and RISA-cisternographic findings typical of an occult normal pressure hydrocephalus. They discuss their personal contribution in the light of what has been already reported in the literature on the same subject. ...

journal_title：European neurology

authors： Mazza S,Laudisio A,Bergonzi P

更新日期：1976-01-01 00:00:00

abstract：:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...

journal_title：European neurology

authors： Terzano MG,Parrino L,Spaggiari MC

更新日期：1990-01-01 00:00:00

abstract：:MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

journal_title：European neurology

authors： Nagatsu T,Hirata Y

更新日期：1987-01-01 00:00:00

abstract：:We wish to retract the paper entitled "Hypovitaminosis D and Decreased Bone Mineral Density in Amyotrophic Lateral Sclerosis" [Eur Neurol 1997; 37: 225-229] by Y. Sato, Y. Honda, T. Asoh, M. Kikuyama, K. Oizumi as a -result of concerns about data integrity and scientific misconduct which have been brought to our atten...

journal_title：European neurology

authors：

更新日期：2018-01-01 00:00:00

abstract：:A 48-year-old woman was referred from Zaire with suspected rabies encephalitis. Survival was 34 days after the onset of symptoms and the diagnosis of rabies was ultimately proven after brain autopsy. Serial neurophysiological investigations, including EEG and multimodality evoked potentials and radiological examinatio...

journal_title：European neurology

authors： Hantson P,Guérit JM,de Tourtchaninoff M,Deconinck B,Mahieu P,Dooms G,Aubert-Tulkens G,Brucher JM

更新日期：1993-01-01 00:00:00

abstract：:The central motor pathways were studied with the technique of percutaneous electrical stimulation of the central nervous system in 40 normal volunteers. There were no significant differences between the right and left sides, or between males and females. A linear correlation between the cortical latency (Lcor) or the ...

journal_title：European neurology

authors： Ugawa Y,Genba K,Shimpo T,Mannen T

更新日期：1989-01-01 00:00:00

abstract：:Many gadolinium-enhanced magnetic resonance imaging (MRI) studies focusing on the anatomy and pathology of the 7th cranial nerve have already been published. However, only scattered cases of herpes zoster oticus (HZO) have been described and only the MRI appearance of the soft temporal bone structures has been reporte...

journal_title：European neurology

authors： Berrettini S,Bianchi MC,Segnini G,Sellari-Franceschini S,Bruschini P,Montanaro D

更新日期：1998-01-01 00:00:00

abstract：:A 24-year-old man presented with dystonia, dementia, amyotrophy, choreoathetosis, and ataxia. Partial hexosaminidase A deficiency was documented in serum and leukocytes and confirmed by rectal biopsy with ganglion cells containing membranous cytoplasmic bodies. A brief review of the literature reveals that tremor, dys...

journal_title：European neurology

authors： Oates CE,Bosch EP,Hart MN

更新日期：1986-01-01 00:00:00

abstract：:During the first 5 days after an intracranial haemorrhage, the red blood cells slowly haemolyse. Most of the oxyhaemoglobin, released in the cerebrospinal fluid, is transformed into bilirubin by an enzyme-dependent process. After 5 days, the haemolysis increases without a corresponding enhancement in the formation of ...

journal_title：European neurology

authors： Wahlgren NG,Lindquist C

更新日期：1987-01-01 00:00:00

abstract：AIM:To determine the association between interleukin-6 (IL-6) and soluble E-selectin (sE-selectin) levels with the electrodiagnostic abnormalities in patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). METHODS:Serum HbA1c, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), f...

journal_title：European neurology

authors： Tiftikcioglu BI,Duksal T,Bilgin S,Kose S,Zorlu Y

更新日期：2016-01-01 00:00:00

abstract：:In order to examine the plasminogen activator (PA) induction involved in the pathogenesis of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS), PA activity in peripheral blood lymphocytes derived from 5 ADEM and 3 MS patients was investigated. There was no PA induction in any ADEM, MS or control ...

journal_title：European neurology

authors： Sugita K,Suzuki N,Shimizu N,Takanashi J,Ishii M,Niimi N

更新日期：1993-01-01 00:00:00

abstract：:Superior orbital fissure syndrome is a symptomatologic complex, consisting of retroorbital pain, paralysis of extraocular muscles, impairment of first trigeminal branches and frequent involvement of the optic nerve. From a review of 130 published cases including two personal observations, it appears that the clinical ...

journal_title：European neurology

authors： Lenzi GL,Fieschi C

更新日期：1977-01-01 00:00:00

abstract：:The Uhthoff symptom, a transient impairment of visual function after exercise, is demonstrated in 2 multiple sclerosis patients. Following exercise, impairment of visual function, as documented most clearly by the testing of contrast sensitivity, was less obvious after body surface cooling and after treatment with ora...

journal_title：European neurology

authors： van Diemen HA,van Dongen MM,Dammers JW,Polman CH

更新日期：1992-01-01 00:00:00

abstract：:The gradual intraneuronal accumulation of an insoluble fibrous material which partly consists of abnormally phosphorylated tau protein (neurofibrillary change) represents an important neuropathological hallmark of Alzheimer's disease. Neurofibrillary tangles and neuropil threads formed from this material develop in on...

journal_title：European neurology

authors： Braak H,Braak E,Bohl J

更新日期：1993-01-01 00:00:00

abstract：:18F-Dopa positron emission tomography (PET) provides a sensitive means of quantitating the loss of nigrostriatal dopaminergic fibres in Parkinson's disease and so can be used to diagnose its presence and to objectively follow the rate of disease progression. It can also be used, in principle, to determine the efficacy...

journal_title：European neurology

authors： Brooks DJ

更新日期：1997-01-01 00:00:00

abstract：:Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...

journal_title：European neurology

authors： de Visser M,Ongerboer de Visser BW,Verbeeten B Jr

更新日期：1988-01-01 00:00:00

abstract：:The pathogenesis of Parkinson's disease (PD) has been linked to oxidative-mediated events including increased monoamine oxidase (MAO) and free-radical generation. We are investigating the ability of the MAO inhibitor, selegiline (deprenyl), and of the free-radical scavenger, tocopherol, to delay the onset of disabilit...

journal_title：European neurology

authors： Shoulson I

更新日期：1992-01-01 00:00:00

abstract：:The European Association of Young Neurologists and Trainees (EAYNT) is a non-profit organization which acts on behalf of young neurologists in Europe and concertedly exerts influence on the formation of a new generation of neurologists [Struhal et al.: Eur J Neurol 2009;16:e146-e148]. This concerns particularly the Ge...

journal_title：European neurology

authors： Struhal W,Falup-Pecurariu C,Sztriha LK,Grisold W,Sellner J

更新日期：2011-01-01 00:00:00

abstract：:Nicorandil, an ATP-sensitive potassium (KATP) channel opener, is known to have protective effects on ischemic injury in heart and brain. One of the most important protective mechanisms is the anti-apoptotic effect on cardiomyocytes and neurons. This study explored the anti-apoptotic effect of nicorandil against neurot...

journal_title：European neurology

authors： Kong J,Ren G,Jia N,Wang Y,Zhang H,Zhang W,Chen B,Cao Y

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex®) is an add-on therapy for moderate-to-severe multiple sclerosis (MS)-related drug-resistant spasticity (MSS). AIM:The MOVE-2 EU study collected data from everyday clinical practice concerning the effectiveness and tolerability of THC:CBD....

journal_title：European neurology

authors： Vermersch P,Trojano M

更新日期：2016-01-01 00:00:00

abstract：:In a 14-year follow-up the improvement of language functions and the decrease of EEG abnormalities are described in a girl with the Landau-Kleffner syndrome. In this case, the results of subsequent EEG recordings do not permit conclusions about the course of the aphasia. Disappearance of focal spike and waves, bilater...

journal_title：European neurology

authors： van Dongen HR,Meulstee J,Blauw-van Mourik M,van Harskamp F

更新日期：1989-01-01 00:00:00

abstract：:Henri Duret (1849-1921) was a surgeon whose training started in the laboratory of Jean-Martin Charcot and Alfred Vulpian at La Salpêtrière in 1874. Using injections of colored gelatine, Duret was the first to describe the distribution of supply arteries in the brainstem and then in the cortex. His descriptions correla...

journal_title：European neurology

authors： Walusinski O,Courrivaud P

更新日期：2014-01-01 00:00:00

abstract：:Sir William Gull coined the name 'anorexia nervosa'. Examples of self-starvation appeared in the Hellenistic era. Holy anorexics abused their bodies, rejected marriage and sought religious asylum where many perished and became saints. The condition then paled into obscurity until the 19th century. Louis-Victor Marce (...

journal_title：European neurology

authors： Pearce JM

更新日期：2004-01-01 00:00:00