Therapies in muscular dystrophy: current concepts and future prospects.

abstract：:In a direct (door-to-door) epidemiological study, the prevalence rate of cerebrovascular disease in the rural population of northwest Peloponnese, Greece, was found to be 995 strokes per 100,000 inhabitants over 20 years of age. This number is considerably lower than the prevalence rate (1,417 strokes per 100,000 inha...

journal_title：European neurology

authors： Paschalis C,Polychronopoulos P,Makris N,Kondakis X,Papapetropoulos T

更新日期：1989-01-01 00:00:00

abstract：:While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both star...

journal_title：European neurology

authors： Bogousslavsky J,Walusinski O,Moulin T

更新日期：2011-01-01 00:00:00

abstract：:18F-Dopa positron emission tomography (PET) provides a sensitive means of quantitating the loss of nigrostriatal dopaminergic fibres in Parkinson's disease and so can be used to diagnose its presence and to objectively follow the rate of disease progression. It can also be used, in principle, to determine the efficacy...

journal_title：European neurology

authors： Brooks DJ

更新日期：1997-01-01 00:00:00

abstract：:Fatigue is one of the most frequent and most disabling symptoms in multiple sclerosis (MS). We investigated the possible association of the MS-related fatigue syndrome with the available disease-modifying therapies and the main disease characteristics in a cross-sectional study on 320 consecutive patients. The prevale...

journal_title：European neurology

authors： Putzki N,Katsarava Z,Vago S,Diener HC,Limmroth V

更新日期：2008-01-01 00:00:00

abstract：:Direct evidence of the anatomical localization of brain function is provided by functional neurological changes during awake surgery combined with data from preoperative functional magnetic resonance imaging and diffusion tensor imaging studies. The goal of the present study was to analyze the etiology and mechanism o...

journal_title：European neurology

authors： Shinoura N,Yoshida M,Yamada R,Tabei Y,Saito K,Suzuki Y,Yagi K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...

journal_title：European neurology

authors： Alvarez-Sabín J,Lozano M,Sastre-Garriga J,Montoyo J,Murtra M,Abilleira S,Codina A

更新日期：2001-01-01 00:00:00

abstract：:The effect of phytohemagglutinin (PHA) and pokeweed mitogen (PWM) on blood lymphocytes was studied in multiple sclerosis, patients with acute CNS infections, and healthy controls. No significant differences in lymphocyte proliferation were registered between the group of MS patients and the two other groups, irrespect...

journal_title：European neurology

authors： Kinnman J,Link H,Frydén A

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Neurosyphilis (NS) is nowadays a less frequent disease. Its incidence and clinical spectrum have changed over time. OBJECTIVE:To estimate the incidence of NS and describe the clinical spectrum of NS in immunocompetent patients in the last decade. METHODS:Demographic and clinical features, cerebrospinal flu...

journal_title：European neurology

authors： Conde-Sendín MA,Amela-Peris R,Aladro-Benito Y,Maroto AA

更新日期：2004-01-01 00:00:00

abstract：:In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

journal_title：European neurology

authors： Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

更新日期：1988-01-01 00:00:00

abstract：AIMS:We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer's disease (AD) patients and the interaction between MTA and WMH. METHODS:From 13 centers, a total of 216 AD patients were consecutivel...

journal_title：European neurology

authors： Shim YS,Youn YC,Na DL,Kim SY,Cheong HK,Moon SY,Park KW,Ku BD,Lee JY,Jeong JH,Kang H,Kim EJ,Lee JS,Go SM,Kim SH,Cha KR,Seo SW

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between metabolic syndrome (MetS) and cognitive impairment in elderly patients with white matter lesions (WML). METHODS:From -January 2016 to June 2017, a cross-sectional study was conducted on the clinical data of 358 WML patients over 65 years old in the Department of Neurology ...

journal_title：European neurology

authors： Chen L,Hong W,Yang H,Dong S,Peng Z,Zhou H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Patients with multiple sclerosis (MS) report sleep disturbances (SD) and excessive daytime sleepiness (EDS) more frequently than the general population. Our objectives were to evaluate SD and EDS in MS patients and to test the reliability of subjective sleep questionnaires. METHODS:Demographic and clinical ...

journal_title：European neurology

authors： Neau JP,Paquereau J,Auche V,Mathis S,Godeneche G,Ciron J,Moinot N,Bouche G

更新日期：2012-01-01 00:00:00

abstract：:Clinical evaluation, quantitative analysis of the EMG, and motor unit fiber density were carried out on 34 selected patients that suffered paralytic poliomyelitis. 50% of the subjects developed a late and slowly progressive weakness. Automatic analysis of the electromyogram showed a great increase in mean amplitude in...

journal_title：European neurology

authors： Cruz Martínez A,Pérez Conde MC,Ferrer MT

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The association between edentulism and cerebral small vessel disease is controversial. We aimed to assess this relationship in community-dwelling older adults living in rural Ecuador. METHODS:MRI was performed in 311 (81%) of 385 individuals ≥60 years enrolled in the Atahualpa Project. Participants were cla...

journal_title：European neurology

authors： Del Brutto OH,Mera RM,Zambrano M

更新日期：2016-01-01 00:00:00

abstract：:Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

journal_title：European neurology

authors： Lutte I,Laterre C,Bodart JM,De Volder A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Intravenous thrombolysis (IVT) with urokinase is the standard reperfusion therapy for acute cerebral infarction (ACI) in China. Only about 30% patients who use urokinase for IVT can recanalize. Therefore, this study aimed to analyze the influencing factors of recanalization after IVT using urokinase in ACI p...

journal_title：European neurology

authors： Zeng J,Wang F,Feng H,Chen F,Wang R,Chen Y,Chen X,Miao J

更新日期：2020-01-01 00:00:00

abstract：:The polymath William Rivers played an important role in his work with Henry Head in demonstrating the varied, evolving patterns of sensory loss, and epicritic and protopathic sensation, after the section of the superficial ramus of Head's left radial nerve. After a mixed and frustrated army career Rivers devoted his a...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:This lecture is mainly concerned with questions about how hemodynamic conditions in atherosclerotic arteries affect arriving platelets that aggregate there and about the chemical agents responsible for making the platelets reactive. The effects of hemodynamic conditions and the agents are known mainly from in vitro ex...

journal_title：European neurology

authors： Born GV

更新日期：1983-01-01 00:00:00

abstract：:Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...

journal_title：European neurology

authors： Hanihara T,Amano N,Takahashi T,Itoh Y,Yagishita S

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The K variant of butyrylcholinesterase (BCHE-K) exhibits a reduced acetylcholine-hydrolyzing capacity; so the clinical response to rivastigmine may differ in Alzheimer's disease (AD) patients with the BCHE-K gene. OBJECTIVE:To investigate the clinical response to rivastigmine transdermal patch monotherapy o...

journal_title：European neurology

authors： Han HJ,Kwon JC,Kim JE,Kim SG,Park JM,Park KW,Park KC,Park KH,Moon SY,Seo SW,Choi SH,Cho SJ

更新日期：2015-01-01 00:00:00

abstract：:The English electrophysiologist Edgar Adrian (1889-1977) was the recipient of the Nobel Prize for physiology in 1932 for his research on the functions of neurons. During World War I, at Queen Square in London, he devised an intensive electrotherapeutic treatment for shell-shocked soldiers. The procedure, developed wit...

journal_title：European neurology

authors： Tatu L

更新日期：2018-01-01 00:00:00

abstract：:After briefly evaluating the contraindications and indications of vasoactive and eumetabolic therapy of cerebral ischemia, the paper considers the main drugs at present in use in therapy of the syndrome induced by diffused cerebral arteriosclerosis. Among the drugs with a mainly vasoactive effect, consideration is giv...

journal_title：European neurology

authors： Strano A,Pinto A,Davì G,Novo S,Riolo F

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Central pontine myelinolysis (CPM)/extrapontine myelinolysis (EPM) is one of the most serious neurological complications that can occur after orthotopic liver transplantation (OLT). We analyzed the risk factors for CPM/EPM in OLT patients. METHODS:We retrospectively reviewed the records of 1,247 patients wh...

journal_title：European neurology

authors： Lee EM,Kang JK,Yun SC,Kim KH,Kim SJ,Hwang KS,Lee SG

更新日期：2009-01-01 00:00:00

abstract：:The present paper is a study of a microcystic intraspinal tumour that developed in a 4-year-old child. The histologic examination showed the presence of neuroblastic elements developing next to smooth muscle fibers. The tumour had diffusely invaded the meninges, presenting a marked collagen reaction. Ultrastructurally...

journal_title：European neurology

authors： Vuia O,Hager H

更新日期：1975-01-01 00:00:00

abstract：:The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...

journal_title：European neurology

authors： Strnad P,Strnadová V

更新日期：1987-01-01 00:00:00

abstract：:The binding of the dopamine uptake inhibitor [3H]GBR-12935 to postmortem putamen from a control group and patients with Alzheimer's disease/senile dementia of Alzheimer type (AD/SDAT) or vascular dementia (VD) was studied. The binding density (Bmax) in AD/SDAT was significantly reduced to 50% of control. A reduction o...

journal_title：European neurology

authors： Allard P,Alafuzoff I,Carlsson A,Eriksson K,Ericson E,Gottfries CG,Marcusson JO

更新日期：1990-01-01 00:00:00

abstract：:A 28-year-old man with negative family history for neuromuscular diseases showed a distal myopathy. Creatine kinase was slightly increased. Two muscle biopsies were performed. The first showed myopathic features, rimmed vacuoles in a limited area and increase of free glycogen; the second showed only nonspecific pathol...

journal_title：European neurology

authors： Mongini T,Doriguzzi C,Palmucci L,Pollo B,Arnaudo E,Bresolin N

更新日期：1989-01-01 00:00:00

abstract：:To examine the possible influence of the blood-CSF barrier function on mathematical formulas for estimating intrathecal IgG production (IgG index, Tourtellotte's formula [TOURT], Schuller and Sagar's formula [Schull], and Reiber and Felgenhauer's formula [IgG(loc)]), we analysed serum and CSF samples from 105 healthy ...

journal_title：European neurology

authors： Blennow K,Fredman P,Wallin A,Gottfries CG,Skoog I,Wikkelsö C,Svennerholm L

更新日期：1993-01-01 00:00:00

abstract：:197 cases of patients with CVI, subjected to surgery by carotid endarterectomy, are examined. The results were nearly always good and hence the technique is recommended. Particular interest is attached to the risk connected with carotid clamping, through intraoperative study of CBF with 133Xe, such a risk is practical...

journal_title：European neurology

authors： Fiorani P,Pistolese GR,Faraglia V,Spartera C

更新日期：1978-01-01 00:00:00

abstract：:The lupus anticoagulant, an immunoglobulin of the IgG or IgM class, is one of a group of antiphospholipid antibodies. Although an anticoagulant in vitro, its action in vivo is that of a procoagulant. This procoagulant activity may involve many organ systems including the nervous system. Thus far cerebral thrombosis, s...

journal_title：European neurology

authors： Englert H,Derue G,Hughes GR

更新日期：1985-01-01 00:00:00