Hemorheological influences on platelet thrombogenesis.

Abstract:

:This lecture is mainly concerned with questions about how hemodynamic conditions in atherosclerotic arteries affect arriving platelets that aggregate there and about the chemical agents responsible for making the platelets reactive. The effects of hemodynamic conditions and the agents are known mainly from in vitro experiments in which aggregation can be quantitatively correlated with blood flow and biochemical effects by simple and reproducible methods; the relevance to the more complicated situations in hemostasis and thrombosis is uncertain. It is difficult to devise quantitative in vivo methods, mainly because of the rapidity with which platelets adhere and aggregate in diseased or damaged blood vessels. Hypotheses for explaining in vivo platelet aggregation in biochemical terms must take the hemodynamic situation into account.

journal_name

Eur Neurol

journal_title

European neurology

authors

Born GV

doi

10.1159/000115608

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

30-4

eissn

0014-3022

issn

1421-9913

journal_volume

22 Suppl 1

pub_type

杂志文章,评审
  • Effect of live attenuated vaccines on the course of experimental allergic encephalomyelitis. A pilot study.

    abstract::The clinical severity of EAE is enhanced by pre-treatment with distemper, measles and BCG vaccine, measles vaccine gives a more severe onset of disease. Rubella vaccine and TAB leads to mild disease which recurs on re-treatment with the appropriate vaccine. These findings and their possible significance in MS are brie...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114898

    authors: Caspary EA

    更新日期:1977-01-01 00:00:00

  • An Elevated High-Sensitivity C-Reactive Protein Level Is Associated with Unfavorable Functional Outcomes of Small-Artery Occlusion in Patients without Diabetes.

    abstract:BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is associated with a risk of causing diabetes mellitus and ischemic stroke. However, the association between hs-CRP levels and functional outcome after small-artery occlusion (SAO) is unknown. METHODS:Data for 836 patients diagnosed with SAO were collected from t...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000477929

    authors: Gao Y,Liu J,Wang W,Gao C,Yu C,Liu S,Wu J

    更新日期:2017-01-01 00:00:00

  • Three-dimensional computed tomography angiography and magnetic resonance angiography of carotid bifurcation stenosis.

    abstract:PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000050752

    authors: Binaghi S,Maeder P,Uské A,Meuwly JY,Devuyst G,Meuli RA

    更新日期:2001-01-01 00:00:00

  • Development of cerebral infarction shortly after intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Cerebral infarction (CI) occurring soon after intracerebral hemorrhage (ICH) has been rarely reported. The purpose of the present study was to characterize this condition and discuss the possible pathophysiology. METHOD:We retrospectively studied 6 patients who developed CI within 10 days after ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000098465

    authors: Kim CH,Kim JS

    更新日期:2007-01-01 00:00:00

  • Tumor progression and serum anti-HuD antibody concentration in patients with paraneoplastic neurological syndromes.

    abstract::The aim of this study was to investigate whether there are clues for a correlation between tumor progression and serum anti-Hu antibody concentration in patients with anti-Hu-associated paraneoplastic neurological syndromes (PNS). 19 patients with anti-Hu-associated PNS were assigned to three groups according to the c...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000057897

    authors: Rauer S,Andreou I

    更新日期:2002-01-01 00:00:00

  • Evaluation of the carotid bifurcation by duplex ultrasound, intravenous and intra-arterial digital subtraction angiography.

    abstract::In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116233

    authors: Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

    更新日期:1988-01-01 00:00:00

  • Observations on the blink reflex.

    abstract::The blink reflex and its equivalent glabella tap reflex are behavioural motor responses normally found in neonates and in the physiological startle reflex. Historically, it was described by Overend in 1896 and soon afterwards by McCarthy and by Bekhterev who disputed its origins. Kugelberg in 1952 recorded the early-l...

    journal_title:European neurology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000114053

    authors: Pearce JM

    更新日期:2008-01-01 00:00:00

  • Clinical, biochemical and neuroimaging parameters after thrombolytic therapy predict long-term stroke outcome.

    abstract:INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000215876

    authors: Brouns R,Sheorajpanday R,Kunnen J,De Surgeloose D,De Deyn PP

    更新日期:2009-01-01 00:00:00

  • Combined damage to the right hemispheric hand area in the primary motor and sensory area plays a critical role in motor hemineglect.

    abstract::Direct evidence of the anatomical localization of brain function is provided by functional neurological changes during awake surgery combined with data from preoperative functional magnetic resonance imaging and diffusion tensor imaging studies. The goal of the present study was to analyze the etiology and mechanism o...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000258636

    authors: Shinoura N,Yoshida M,Yamada R,Tabei Y,Saito K,Suzuki Y,Yagi K

    更新日期:2010-01-01 00:00:00

  • Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo.

    abstract::MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116350

    authors: Nagatsu T,Hirata Y

    更新日期:1987-01-01 00:00:00

  • Chronic partial denervation is more widespread than is suspected clinically in paralytic poliomyelitis. Electrophysiological study.

    abstract::Clinical evaluation, quantitative analysis of the EMG, and motor unit fiber density were carried out on 34 selected patients that suffered paralytic poliomyelitis. 50% of the subjects developed a late and slowly progressive weakness. Automatic analysis of the electromyogram showed a great increase in mean amplitude in...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115578

    authors: Cruz Martínez A,Pérez Conde MC,Ferrer MT

    更新日期:1983-01-01 00:00:00

  • Styrene-induced peripheral neuropathy. A case report.

    abstract::A case of peripheral neuropathy due to styrene is described. The diagnosis of peripheral neuropathy was confirmed by a motor-nerve conduction study and sural nerve biopsy. ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116046

    authors: Behari M,Choudhary C,Roy S,Maheshwari MC

    更新日期:1986-01-01 00:00:00

  • Diagnostic problems in multiple sclerosis. Two cases with clinical diagnosis of MS showing only a diffusely growing malignant astrocytoma.

    abstract::Two cases are presented with a long clinical history of multiple sclerosis (MS) before the diagnosis of an intracranial brain tumor. In the subsequent brain autopsy, however, both cases presented a diffusely growing anaplastic astrocytoma, only, and no changes similar to MS were seen. Diffuse tumor growth was noted in...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116009

    authors: Röyttä M,Latvala M

    更新日期:1986-01-01 00:00:00

  • Proust, neurology and Stendhal's syndrome.

    abstract::Marcel Proust is one of the most important French writers of the 20th century. His relationship with medicine and with neurology is possibly linked to the fact that his asthma was considered to be a psychosomatic disease classified as neurasthenia. Stendhal's syndrome is a rare psychiatric syndrome characterized by an...

    journal_title:European neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1159/000357562

    authors: Teive HA,Munhoz RP,Cardoso F

    更新日期:2014-01-01 00:00:00

  • Silent coronaropathy: usefulness of dobutamine stress echocardiography in ischemic stroke.

    abstract:BACKGROUND:Several testing options are available to detect asymptomatic coronary artery disease (CAD). Dobutamine stress echocardiography (DSE) has been reported to increase the sensitivity and specificity of stress testing to detect CAD. Most studies concerned patients with known or suspected CAD who have a high prete...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000096488

    authors: Nighoghossian N,Cakmak S,Derex L,Barthelet M,Thibault H,Finet G,Ovize M,Derumeaux G,Nemoz C,Chapuis F,Rioufol G

    更新日期:2006-01-01 00:00:00

  • Electromyographic and computed tomographic findings in five patients with monomelic spinal muscular atrophy.

    abstract::Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116249

    authors: de Visser M,Ongerboer de Visser BW,Verbeeten B Jr

    更新日期:1988-01-01 00:00:00

  • Superior orbital fissure syndrome. Review of 130 cases.

    abstract::Superior orbital fissure syndrome is a symptomatologic complex, consisting of retroorbital pain, paralysis of extraocular muscles, impairment of first trigeminal branches and frequent involvement of the optic nerve. From a review of 130 published cases including two personal observations, it appears that the clinical ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000114876

    authors: Lenzi GL,Fieschi C

    更新日期:1977-01-01 00:00:00

  • Long-term follow-up EEG studies in patients with traumatic apallic syndrome.

    abstract::The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116316

    authors: Strnad P,Strnadová V

    更新日期:1987-01-01 00:00:00

  • Extracranial Venous Drainage Pattern in Multiple Sclerosis and Healthy Controls: Application of the 2011 Diagnostic Criteria for Chronic Cerebrospinal Venous Insufficiency.

    abstract::The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alte...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000445540

    authors: Cardaioli G,Di Filippo M,Bianchi A,Eusebi P,Di Gregorio M,Gaetani L,Gallina A,Calabresi P,Sarchielli P

    更新日期:2016-01-01 00:00:00

  • The side and somatotopical location of single small infarcts in the corona radiata and pontine base in relation to contralateral limb paresis and dysarthria.

    abstract::The aim of this study was to investigate whether the side and location of single small infarcts (< or = 3 cm) in the corona radiata (28 patients) and pontine base (36 patients) influence the incidence of contralateral upper or lower limb paresis and dysarthria. While the severity of contralateral limb paresis was not ...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000117290

    authors: Tohgi H,Takahashi S,Takahashi H,Tamura K,Yonezawa H

    更新日期:1996-01-01 00:00:00

  • Hypertrophy of the inferior olivary nucleus in patients with progressive supranuclear palsy.

    abstract::Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000007915

    authors: Hanihara T,Amano N,Takahashi T,Itoh Y,Yagishita S

    更新日期:1998-01-01 00:00:00

  • Therapies in muscular dystrophy: current concepts and future prospects.

    abstract::In the fast moving field of muscular dystrophy, therapeutic matters are now high on the agenda. Despite little progress made in the understanding of the exact pathogenesis, hopes have been raised with the advent of molecular medicine applied to such disorders. A constellation of techniques or therapeutic solutions are...

    journal_title:European neurology

    pub_type: 杂志文章,评审

    doi:10.1159/000008150

    authors: Urtizberea JA

    更新日期:2000-01-01 00:00:00

  • Landau-Kleffner syndrome: a case study with a fourteen-year follow-up.

    abstract::In a 14-year follow-up the improvement of language functions and the decrease of EEG abnormalities are described in a girl with the Landau-Kleffner syndrome. In this case, the results of subsequent EEG recordings do not permit conclusions about the course of the aphasia. Disappearance of focal spike and waves, bilater...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000116390

    authors: van Dongen HR,Meulstee J,Blauw-van Mourik M,van Harskamp F

    更新日期:1989-01-01 00:00:00

  • Multiphasic perfusion computed tomography as a predictor of collateral flow in acute ischemic stroke: comparison with digital subtraction angiography.

    abstract:BACKGROUND:Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS:Conse...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000334867

    authors: Kim SJ,Noh HJ,Yoon CW,Kim KH,Jeon P,Bang OY,Kim GM,Chung CS,Lee KH

    更新日期:2012-01-01 00:00:00

  • Reports of patients and relatives from the CogniCIS study about cognition in clinically isolated syndrome: what are our patients telling us?

    abstract:OBJECTIVE:To assess the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) in patients with clinically isolated syndrome (CIS). METHODS:130 European CIS patients and 60 relatives completed the MSNQ. RESULTS:The mean (SD) MSNQ score for CIS patients was 15.5 (10.8) and for their informants 11.3 (9.6). Neither ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000345698

    authors: Langdon DW,Benedict RH,Wicklein EM,Beckmann K,Fredrikson S

    更新日期:2013-01-01 00:00:00

  • Metabolic Disorders in Patients with Central Nervous System Infections: Associations with Neurosyphilis.

    abstract:INTRODUCTION:Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. METHODS:An in-depth ...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000503626

    authors: Xiao Y,Chen MJ,Shen X,Lin LR,Liu LL,Yang TC,Niu JJ

    更新日期:2019-01-01 00:00:00

  • Spinal dural arteriovenous fistulas: an underestimated cause of myelopathy.

    abstract::13 patients with spinal dural arteriovenous fistulas (DAVF) diagnosed in our Institution have been the object of this study. The necessity to include the disease in the differential diagnosis with other pathologies affecting the lower thoracic cord, particularly in middle-aged and old males, is emphasized. Involvement...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000117015

    authors: Bradac GB,Daniele D,Riva A,Bracchi M,Stura G,Riccio A,Pagni CA

    更新日期:1994-01-01 00:00:00

  • Tumor necrosis factor-alpha-308 gene polymorphism in Croatian and Slovenian multiple sclerosis patients.

    abstract::Previous findings regarding the role of TNF-alpha-308 gene polymorphism in multiple sclerosis (MS) are contradictory. The aim of this study was to investigate the possible influence of TNF-alpha-308 polymorphism on MS susceptibility and the MS disease process in a Croatian and Slovenian population. Genotyping was perf...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000099159

    authors: Ristić S,Lovrecić L,Starcević-Cizmarević N,Brajenović-Milić B,Sega Jazbec S,Sepcić J,Kapović M,Peterlin B

    更新日期:2007-01-01 00:00:00

  • Fisher's syndrome following trigeminal herpes zoster.

    abstract::A case of Fisher's syndrome associated with trigeminal herpes zoster is reported for the first time. Retrograde propagation of the virus to the brainstem through the trigeminal root was thought to be the most probable pathogenic mechanism. We provide additional evidence suggesting that the focus of Fisher's syndrome i...

    journal_title:European neurology

    pub_type: 杂志文章

    doi:10.1159/000115817

    authors: Uematsu D,Satoh T,Tanahashi N,Koto A,Gotoh F

    更新日期:1985-01-01 00:00:00

  • Carbamazepine versus diphenylhydantoin in the treatment of myotonia.

    abstract::A double-blind controlled trial was performed on 6 patients affected with Steinert's disease in order to evaluate the efficacy of two different dosages of diphenylhydantoin (PHT, 200 and 300 mg/day) and carbamazepine (CBZ, 600 and 800 mg/day) on the myotonic afterdischarge. Both dosages of PHT and CBZ induced a signif...

    journal_title:European neurology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000115546

    authors: Sechi GP,Traccis S,Durelli L,Monaco F,Mutani R

    更新日期:1983-01-01 00:00:00