Effects of GM1 ganglioside in cerebrovascular diseases: a double-blind trial in 40 cases.

abstract：:Many gadolinium-enhanced magnetic resonance imaging (MRI) studies focusing on the anatomy and pathology of the 7th cranial nerve have already been published. However, only scattered cases of herpes zoster oticus (HZO) have been described and only the MRI appearance of the soft temporal bone structures has been reporte...

journal_title：European neurology

authors： Berrettini S,Bianchi MC,Segnini G,Sellari-Franceschini S,Bruschini P,Montanaro D

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:A marked proportion of multiple sclerosis (MS) relapses is followed by incomplete recovery. Our aim was to considerably increase the evidence of the clinical use of immunoadsorption (IA) as escalation therapy for patients with MS relapse. METHODS:A retrospective multicenter study was performed in MS patient...

journal_title：European neurology

authors： Schimrigk S,Faiss J,Köhler W,Günther A,Harms L,Kraft A,Ehrlich S,Eberl A,Fassbender C,Klingel R,Galle J,Riedlinger A,Hoffmann F

更新日期：2016-01-01 00:00:00

abstract：:The association of anaemia and gastro-intestinal abnormalities with disorders of the brain, spinal cord, and peripheral nerves has been recognized since the mid 19th century. In early reports interpretable as subacute combined degeneration, anaemia was overlooked, and conversely in Addison's and other early reports of...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:A 47-year-old woman presented with paralysis of upward gaze associated with Addison's pernicious anaemia. Administration of cyanocobalamin resulted in significant improvement of eye movements and haematological parameters. Isolated paralysis of upward gaze may be a feature of vitamin B12 deficiency. ...

journal_title：European neurology

authors： Sandyk R

更新日期：1984-01-01 00:00:00

abstract：:The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...

journal_title：European neurology

authors： Simuni T,Lyons KE,Pahwa R,Hauser RA,Comella C,Elmer L,Weintraub D

更新日期：2009-01-01 00:00:00

abstract：:The clinical and biochemical data on 13 patients with Batten's syndrome are described. Clinically the disease was characterized by progressive maental and somatic deterioration. Initially, vision loss was found between the ages 4 and 8 years. This was associated with 1 or 2 years of normal school attendance followed b...

journal_title：European neurology

authors： Jensen GE,Clausen J,Melchior JC,Konat G

更新日期：1977-01-01 00:00:00

abstract：:Estrogen receptor (ER) analysis was performed with an enzyme immunoassay using monoclonal antibodies against human ER protein (estrophilin) in 70 meningiomas. [3H]methyltrienolone, a synthetic androgen, was used for concurrent determination of the androgen receptor (AR)-binding activity. Low levels of ER immunoreactiv...

journal_title：European neurology

authors： Lesch KP,Schott W,Engl HG,Gross S

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Locked-in syndrome (LIS) is a condition characterized by quadriplegia and anarthria. The most common cause is a ventral pontine lesion due to atherosclerotic basilar artery disease. METHODS:Cases with LIS were prospectively identified among the patients with acute ischemic stroke over 3 years, between 2009 ...

journal_title：European neurology

authors： Nikić PM,Jovanović D,Paspalj D,Georgievski-Brkić B,Savić M

更新日期：2013-01-01 00:00:00

abstract：:The biochemical process underlying Parkinson's disease is dopamine cell death of the nigrostriatal system. The age-dependent cell death is now proposed to be elicited by the formation of free hydroxy radicals which are formed from hydrogen peroxide, a product of oxidation of dopamine by monoamine oxidase, especially t...

journal_title：European neurology

authors： Naoi M,Maruyama W

更新日期：1993-01-01 00:00:00

abstract：:L-Dopa pioneered the symptomatic therapy of Parkinson's disease. While this treatment proved effective in the treatment of parkinsonian akinesia, rigidity and tremor, prolonged L-dopa treatment was often noted to result in dyskinesia, psychosis and 'on-off' phenomena. This increasing disability of L-Dopa-treated parki...

journal_title：European neurology

authors： Kuno S

更新日期：1994-01-01 00:00:00

abstract：:Increased levels of lactic dehydrogenase (LDH) in cerebrospinal fluid (CSF) have been reported in association with several intracranial pathologies. We studied LDH isoenzymes in the CSF of children with infantile spasms. CSF samples collected from 12 patients (aged 4-9 months) with infantile spasms were analyzed for t...

journal_title：European neurology

authors： Nussinovitch M,Harel D,Eidlitz-Markus T,Amir J,Volovitz B

更新日期：2003-01-01 00:00:00

abstract：:MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

journal_title：European neurology

authors： Nagatsu T,Hirata Y

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS). MATERIALS AND METHODS:Twenty-five patient...

journal_title：European neurology

authors： Binaghi S,Maeder P,Uské A,Meuwly JY,Devuyst G,Meuli RA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...

journal_title：European neurology

authors： Steinhoff BJ,Hartmann R,Luy M,Rombach A,Ziegler G,Schulte-Mönting J,Gilliam FG

更新日期：2010-01-01 00:00:00

abstract：:The effect of oral treatment with acyclovir (ACV) on sensory axonal neuropathy, segmental motor paresis and postherpetic neuralgia (PHN) was studied in 105 patients with herpes zoster. Forty-seven patients were treated with ACV at a dose of 4 g/day in 5 doses for at least a week; the others did not undergo any kind of...

journal_title：European neurology

authors： Mondelli M,Romano C,Passero S,Porta PD,Rossi A

更新日期：1996-01-01 00:00:00

abstract：:SJL/J mice have been studied as the model animals for autoimmunological diseases. Recently it was clarified that SJL/J mice have a defect of dysferlin. Human limb girdle muscular dystrophy 2B and Miyoshi myopathy also have a defect of dysferlin. In this study we present the histological and immunohistological changes ...

journal_title：European neurology

authors： Nemoto H,Konno S,Nakazora H,Miura H,Kurihara T

更新日期：2007-01-01 00:00:00

abstract：:Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...

journal_title：European neurology

authors： Pearce JM

更新日期：2007-01-01 00:00:00

abstract：:Anticonvulsant therapy was stopped in 191 epileptic children (109 males and 82 females) after a seizure-free period of at least 2 years, independent of EEG findings, followed up for a minimum of 2 years after withdrawal. Overall, 43 (22.5%) had recurrence of seizures; of these, 79% relapsed within the 1st year after d...

journal_title：European neurology

authors： Mastropaolo C,Tondi M,Carboni F,Manca S,Zoroddu F

更新日期：1992-01-01 00:00:00

abstract：:Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...

journal_title：European neurology

authors： de Visser M,Ongerboer de Visser BW,Verbeeten B Jr

更新日期：1988-01-01 00:00:00

abstract：:The role of genetics in Parkinson's disease (PD), previously controversial, is now supported by several studies. A major breakthrough has been the discovery of a single gene defect in familial Parkinson's disease. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein g...

journal_title：European neurology

authors： Hu CJ,Sung SM,Liu H,Chang JG

更新日期：1999-01-01 00:00:00

abstract：:Five patients with clinical features of corticobasal degeneration (CBD) were studied with PET imaging. The main clinical findings included a unilateral extrapyramidal motor disorder, without significant response to levodopa, as well as clumsiness, dysarthria, apraxia and a clear asymmetry of neurological signs. PET st...

journal_title：European neurology

authors： Lutte I,Laterre C,Bodart JM,De Volder A

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study was to investigate whether there are clues for a correlation between tumor progression and serum anti-Hu antibody concentration in patients with anti-Hu-associated paraneoplastic neurological syndromes (PNS). 19 patients with anti-Hu-associated PNS were assigned to three groups according to the c...

journal_title：European neurology

authors： Rauer S,Andreou I

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiac myxomas may present clinically with many different features. Since highly effective treatments exist, it is important that they are diagnosed quickly in order to avoid further complications. Our aim was to determine the influence of neurological presentation in diagnosis and prognosis of car...

journal_title：European neurology

authors： Alvarez-Sabín J,Lozano M,Sastre-Garriga J,Montoyo J,Murtra M,Abilleira S,Codina A

更新日期：2001-01-01 00:00:00

abstract：:The binding of the dopamine uptake inhibitor [3H]GBR-12935 to postmortem putamen from a control group and patients with Alzheimer's disease/senile dementia of Alzheimer type (AD/SDAT) or vascular dementia (VD) was studied. The binding density (Bmax) in AD/SDAT was significantly reduced to 50% of control. A reduction o...

journal_title：European neurology

authors： Allard P,Alafuzoff I,Carlsson A,Eriksson K,Ericson E,Gottfries CG,Marcusson JO

更新日期：1990-01-01 00:00:00

abstract：:Fluctuations in motor performance and dyskinesias are a common problem in the long-term management of Parkinson's disease. The pharmacokinetics and the pharmacodynamics of levodopa, loss of presynaptic dopamine terminals, alterations in postsynaptic dopamine receptor sensitivity, or changes in the modulatory influence...

journal_title：European neurology

authors： Stocchi F,Bonamartini A,Vacca L,Ruggieri S

更新日期：1996-01-01 00:00:00

abstract：:Here we review a total of 17 patients, including 4 of our own, with young-adult-onset arteriosclerotic leukoencephalopathy, alopecia and lumbago without hypertension. All were Japanese and the illness seemed to be transmitted in an autosomal recessive fashion. The male to female ratio was 7.5:1. The age of onset usual...

journal_title：European neurology

authors： Fukutake T,Hirayama K

更新日期：1995-01-01 00:00:00

abstract：:The authors describe a case where a parkinsonian symptomatology is associated with pneumoencephalographic and RISA-cisternographic findings typical of an occult normal pressure hydrocephalus. They discuss their personal contribution in the light of what has been already reported in the literature on the same subject. ...

journal_title：European neurology

authors： Mazza S,Laudisio A,Bergonzi P

更新日期：1976-01-01 00:00:00

abstract：:Of 150 new cases of nasopharyngeal carcinoma diagnosed in Israel during a 9-year period (nationwide study 1960--1968), 74 patients developed neurological complications. In 92% of the cases, neurologic deficits were confined exclusively to cranial nerves. The majority of these patients presented general symptoms of dis...

journal_title：European neurology

authors： Turgman J,Braham J,Modan B,Goldhammer Y

更新日期：1978-01-01 00:00:00

abstract：:Current treatment options for restless legs syndrome (RLS), based on the American Academy of Sleep Medicine practice parameters, favor dopaminergic agents. The drug of first choice is levodopa, which is now licensed for RLS in two European countries. However, the short duration of action and augmentation of symptoms u...

journal_title：European neurology

authors： Stiasny K

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke's encephalopathy with cortical abnormalities (WEc). METHODS:We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. RESULTS:Besides the cla...

journal_title：European neurology

authors： Sakurai K,Sasaki S,Hara M,Yamawaki T,Shibamoto Y

更新日期：2009-01-01 00:00:00