Abstract:
BACKGROUND:Intravenous thrombolysis (IVT) with urokinase is the standard reperfusion therapy for acute cerebral infarction (ACI) in China. Only about 30% patients who use urokinase for IVT can recanalize. Therefore, this study aimed to analyze the influencing factors of recanalization after IVT using urokinase in ACI patients. METHODS:A total of 391 consecutive patients with a diagnosis of ACI from January 2013 to October 2019 were enrolled and divided into 2 groups: patients without recanalization and patients with recanalization. Related data were collected and analyzed. RESULTS:Univariate analysis showed that there were significant differences in gender, atrial fibrillation, erythrocyte mean corpuscular volume, platelet large cell ratio (P-LCR), glucose (GLU), and severity of ICAS between patients without recanalization and patients with recanalization (p < 0.05). Multivariate logistic regression analysis indicated that P-LCR (odds ratio [OR] = 0.17, 95% confidence interval [CI] = 0.03-0.89, p = 0.04), GLU (OR = 0.28, 95% CI = 0.11-0.67, p = 0.004), and ICAS severity (OR = 0.48, 95% CI = 0.32-0.76, p = 0.001) were the influencing factors of recanalization. CONCLUSION:For patients with higher levels of P-LCR, GLU, or ICAS severity, the recanalization rate might decrease after ACI.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Zeng J,Wang F,Feng H,Chen F,Wang R,Chen Y,Chen X,Miao Jdoi
10.1159/000507288subject
Has Abstractpub_date
2020-01-01 00:00:00pages
162-166issue
2eissn
0014-3022issn
1421-9913pii
000507288journal_volume
83pub_type
杂志文章abstract::The objective of this work was to precisely analyse the reduction of the antiparkinsonian treatment in 18 consecutive patients with Parkinson's disease (PD) operated on for bilateral subthalamic nucleus (STN) stimulation, first after 1 month of follow-up, then at 1 year postoperatively. Trihexyphenidyle, selegiline, e...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000067028
更新日期:2003-01-01 00:00:00
abstract::64 patients on hemodialysis were investigated. The mean duration of dialysis was 43 months. In all the patients, serum aluminium levels, systolic blood pressure (averaged over a period of 6 weeks) and the EEG were investigated. Psychological testing to assess the level of intelligence (IQ) was also performed. The seru...
journal_title:European neurology
pub_type: 杂志文章
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journal_title:European neurology
pub_type: 杂志文章,随机对照试验
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abstract::Mitochondrial abnormalities and effectiveness of replacement therapy were examined in a murine model of systemic carnitine deficiency, namely the juvenile visceral steatosis (JVS) mouse. Homozygous JVS mice revealed severe lipid deposition and abnormal mitochondria in liver, heart, skeletal muscle, and kidney, but the...
journal_title:European neurology
pub_type: 杂志文章
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doi:10.1159/000116408
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journal_title:European neurology
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doi:10.1159/000324335
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pub_type: 临床试验,杂志文章
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更新日期:1981-01-01 00:00:00