Abstract:
:The protein kinase D family of enzymes consists of three isoforms: PKD1/PKCmu PKD2 and PKD3/PKCnu. They all share a similar architecture with regulatory sub-domains that play specific roles in the activation, translocation and function of the enzymes. The PKD enzymes have recently been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Rykx A,De Kimpe L,Mikhalap S,Vantus T,Seufferlein T,Vandenheede JR,Van Lint Jdoi
10.1016/s0014-5793(03)00487-3keywords:
subject
Has Abstractpub_date
2003-07-03 00:00:00pages
81-6issue
1eissn
0014-5793issn
1873-3468pii
S0014579303004873journal_volume
546pub_type
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