The oncogenic potential of PRR11 gene in Tongue Squamous Cell Carcinoma cells.

abstract：:Fallopian tube epithelial cells (FTECs) are thought to be the origin of epithelial ovarian cancer. However, the effect of the hormones on FTECs is unknown, and therefore, this study explored this effect. We successfully derived FTECs from the fallopian tube epithelial layer and treated them with estradiol and progeste...

journal_title：Journal of Cancer

authors： Chang YH,Ding DC,Chu TY

更新日期：2019-06-02 00:00:00

abstract：:Background: Integrative oncology (IO) is a relatively new field that seeks to bring evidence-based, non-conventional approaches into conventional oncology care in a coordinated and safe manner. Though complementary and alternative medicine (CAM) are highly utilized by cancer patients, little is known about the charact...

journal_title：Journal of Cancer

authors： Lopez G,McQuade J,Cohen L,Williams JT,Spelman AR,Fellman B,Li Y,Bruera E,Lee RT

更新日期：2017-02-10 00:00:00

abstract：:Levels of plasma cell-free DNA (cfDNA) of a large series of children with classical Hodgkin lymphoma (cHL) were evaluated and analyzed at diagnosis and during chemotherapy treatment in relation with clinical characteristics. CfDNA levels in cHL patients were significantly higher compared with controls (p=0.002). CfDNA...

journal_title：Journal of Cancer

authors： Primerano S,Burnelli R,Carraro E,Pillon M,Elia C,Farruggia P,Sala A,Vinti L,Buffardi S,Basso G,Mascarin M,Mussolin L

更新日期：2016-01-12 00:00:00

abstract：:Ovarian carcinoma is the most lethal gynecological malignancy worldwide. Recent advance in genomic/epigenomic researches will impact on our prevention, detection and intervention on ovarian carcinoma. Detection of germline mutations in BRCA1/BRCA2, mismatch repair genes, and other genes in the homologous recombination...

journal_title：Journal of Cancer

authors： Dong A,Lu Y,Lu B

更新日期：2016-07-05 00:00:00

abstract：:Background: HER2 serves as an important therapeutic target in gastroesophageal cancer. Differences in HER2 gene signal distribution patterns can be observed at the tissue level, but how it influences the HER2 amplification status has not been studied so far. Here, we investigated the link between HER2 amplification an...

journal_title：Journal of Cancer

authors： Jørgensen JT,Nielsen KB,Kjærsgaard G,Jepsen A,Mollerup J

更新日期：2017-06-01 00:00:00

abstract：:Purpose: The early BCR-ABL1 reduction had the prognostic impact of the chronic-phase chronic myeloid leukemia (CML-CP) patients. This study was to find a more precise early prognosis index at 3 months in the patients with newly diagnosed CML-CP, especially for the patients with BCR-ABL1IS >10%. Methods: We retrospecti...

journal_title：Journal of Cancer

authors： Cai Z,Jia X,Zi J,Song H,Wang S,McGrath M,Zhao L,Song C,Ge Z

更新日期：2020-02-03 00:00:00

abstract：:Background: Bevacizumab combined with chemotherapy is still one of the standard options for treatment of advanced non-small cell lung cancer (NSCLC) patients without driver mutations. Serum inflammatory factors, representing the systemic immune status, are shown to have complicated relationships with tumor angiogenesi...

journal_title：Journal of Cancer

authors： Li B,Wang S,Li C,Guo M,Xu Y,Sun X,Yu J,Wang L

更新日期：2019-08-28 00:00:00

abstract：PURPOSE:Methotrexate, vinblastine, doxorubicin plus cisplatin (MVAC) and gemcitabine plus cisplatin (GC) are both effective first-line chemotherapy. We explore the responsive variables of MVAC and GC for patients with metastatic urothelial carcinoma of bladder (mUCB). MATERIALS AND METHODS:Patients who were initially ...

journal_title：Journal of Cancer

authors： Hsieh MC,Huang CH,Chiang PH,Chen YY,Tang Y,Su YL

更新日期：2016-06-27 00:00:00

abstract：:Purpose: We retrospectively collected consecutive survival data of lung adenosquamous cell carcinoma (ASC) patients with brain metastasis (BM) in our institute and discussed the factors related to prognosis of these patients. Patients and Methods: A total of 42 patients diagnosed as lung ASC with BM between July 1, 20...

journal_title：Journal of Cancer

authors： Pan F,Cui S,Wang W,Gu A,Jiang L

更新日期：2018-09-08 00:00:00

abstract：:Several studies have reported the association between MAPK signaling pathway gene polymorphisms and papillary thyroid carcinoma (PTC). KRAS gene, an oncogene from the mammalian RAS gene family plays an important role in the MAPK pathway. This study aimed to identify the potential association of KRAS gene polymorphisms...

journal_title：Journal of Cancer

authors： Ning L,Rao W,Yu Y,Liu X,Pan Y,Ma Y,Liu R,Zhang S,Sun H,Yu Q

更新日期：2016-12-09 00:00:00

abstract：:Background and objective: Long-term aspirin use for the primary prevention of cancer remains controversial, and variations in the effect of aspirin use on cancer outcomes by aspirin dose, follow-up duration, or study population have never been systematically evaluated. The objective of this study was to evaluate the e...

journal_title：Journal of Cancer

authors： Wu Q,Yao X,Chen H,Liu Z,Li T,Fan X,Zhang G,Yu L,Chen M,Xu C,Zhang R,Chen B,Sui X,Leung EL

更新日期：2020-09-14 00:00:00

abstract：:Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy from surgery, chemotherapy, to radiotherapy. Efforts in recent decades have brought many novel therapies to light, however, with limitations. In...

journal_title：Journal of Cancer

authors： Zhang H,Wang R,Yu Y,Liu J,Luo T,Fan F

更新日期：2019-08-27 00:00:00

abstract：:The authors retrospectively examined the contralateral prophylactic mastectomy (CPM) rate among 100 women with ductal carcinoma in situ who are BRCA negative. Of 100 women with ductal carcinoma in situ, 31 elected contralateral prophylactic mastectomy (CPM). Factors associated with increased likelihood of undergoing c...

journal_title：Journal of Cancer

authors： Elsayegh N,Profato J,Barrera AM,Lin H,Kuerer HM,Ardic C,Litton JK,Tripathy D,Arun BK

更新日期：2015-05-23 00:00:00

abstract：PURPOSE:Triple-negative breast cancer (TNBC) has attracted more attention both clinically and experimentally because of its high-risk biological characteristics and lacking of effective treatment method. The purpose of this retrospective study was to find out the incidence of triple-negative breast cancer (TNBC) in all...

journal_title：Journal of Cancer

authors： Qiu J,Xue X,Hu C,Xu H,Kou D,Li R,Li M

更新日期：2016-01-01 00:00:00

abstract：:Purpose: Extremity soft tissue leiomyosarcoma (LMS) with metastasis is a rare disease with a poor prognosis. The purpose of our study was to define clinical features of extremity soft tissue LMS with metastasis as well as to identify multivariable predictors of survival. Methods: During 1973-2015, 239 patients with me...

journal_title：Journal of Cancer

authors： Qian SJ,Wu JQ,Wang Z,Zhang B

更新日期：2019-05-21 00:00:00

abstract：:Background: Proverbially, the incidence rate of papillary thyroid carcinoma (PTC) has increased year by year. Many long noncoding RNAs (lncRNAs) have been discovered having a relationship with tumor genesis tightly recently. Thanks to the previous researches, we found long intergenic noncoding RNA 00511 (LINC00511) is...

journal_title：Journal of Cancer

authors： Xiang J,Guan Y,Bhandari A,Xia E,Wen J,Wang O

更新日期：2020-01-01 00:00:00

abstract：:Objective: To measure hematologic parameters derived from the white blood cell (WBC) count and differential count (DC) as prognostic factors for survival in patients with stage IB and IIA cervical cancer. Methods: We retrospectively examined demographic, clinicopathologic, and laboratory parameters in a cohort of 233 ...

journal_title：Journal of Cancer

authors： Eo WK,Kwon BS,Kim KH,Kim HY,Kim HB,Koh SB,Chun S,Ji YI,Lee JY,Namkung J,Kwon S

更新日期：2018-01-01 00:00:00

abstract：:Purpose: The objective of this study was to develop and validate a nomogram for predicting the cancer-specific survival (CSS) in patients with Wilms' tumor (WT). Methods: Patients with WT diagnosed between 2002 and 2015 in the Surveillance, Epidemiology, and End Results (SEER) database were divided randomly into train...

journal_title：Journal of Cancer

authors： Pan Z,You H,Bu Q,Feng X,Zhao F,Li Y,Lyu J

更新日期：2019-08-28 00:00:00

abstract：:For many years, the medical treatment of breast cancer was reliant solely on cytotoxic chemotherapy. However, over the past twenty years, treatment has evolved to a more target-directed approach. We now employ tailored therapy based on the presence or absence of receptors for estrogen, progesterone, and human epiderma...

journal_title：Journal of Cancer

authors： Tinoco G,Warsch S,Glück S,Avancha K,Montero AJ

更新日期：2013-01-01 00:00:00

abstract：:Background and aim: Understanding the molecular biological mechanisms underlying laryngeal squamous cell carcinoma (LSCC) invasion and metastasis is crucial for diagnosis, treatment, and prognosis. We aimed to examine the expression of the tumor suppressor microRNA-204-5p (miR-204-5p) and its target gene, forkhead box...

journal_title：Journal of Cancer

authors： Gao W,Wu Y,He X,Zhang C,Zhu M,Chen B,Liu Q,Qu X,Li W,Wen S,Wang B

更新日期：2017-07-21 00:00:00

abstract：:Centromere protein N (CENP-N), an important member of the centromere protein family, is essential for kinetochore assembly and chromosome segregation; however, the relevance of CENP-N in cancers remains unknown. The aim of this study was to investigate CENP-N expression and its functional mechanisms in oral squamous c...

journal_title：Journal of Cancer

authors： Oka N,Kasamatsu A,Endo-Sakamoto Y,Eizuka K,Wagai S,Koide-Ishida N,Miyamoto I,Iyoda M,Tanzawa H,Uzawa K

更新日期：2019-06-09 00:00:00

abstract：:Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The metabolomic approaches are developed to discover the novel biomarkers of PDAC. Methods: 550 preoperative, postoperative PDAC and normal controls (NCs) serums were employed to characterize metabolic alterations in ...

journal_title：Journal of Cancer

authors： Zhang X,Shi X,Lu X,Li Y,Zhan C,Akhtar ML,Yang L,Bai Y,Zhao J,Wang Y,Yao Y,Li Y,Nie H

更新日期：2020-05-19 00:00:00

abstract：:Background: Malnutrition and systemic inflammatory response are frequently associated with prognosis in patients with several types of cancer, including renal cell carcinoma (RCC). The study is aimed to investigate the ability of preoperative serum albumin to globulin ratio (AGR) to predict the long-term mortality of ...

journal_title：Journal of Cancer

authors： He X,Guo S,Chen D,Yang G,Chen X,Zhang Y,He Q,Qin Z,Liu Z,Xue Y,Zhang M,Liu R,Zhou F,Han H,Yao K

更新日期：2017-01-15 00:00:00

abstract：:Endometrial and ovarian cancers are two most common cancers affecting women in their post-menopausal years. To date, there are no simple biochemical tests to detect these cancers at early stages. Our previous study has demonstrated that the activity of total proprotein convertases (PCs) is significantly increased in u...

journal_title：Journal of Cancer

authors： Heng S,Stephens AN,Jobling TW,Nie G

更新日期：2016-08-12 00:00:00

abstract：:Establishing an applicable preclinical model is vital for translational cancer research. Patient-derived xenograft has been important preclinical model systems and widely used for cancer research. Patient-derived xenograft models that represent the tumors of the patients are necessary to better translate research disc...

journal_title：Journal of Cancer

authors： Chen C,Lin W,Huang Y,Chen X,Wang H,Teng L

更新日期：2021-01-01 00:00:00

abstract：:Objectives: LncRNA associated with microvascular invasion in hepatocellular carcinoma (lncRNA MVIH) is a newly discovered long non-coding RNA that aberrantly up-regulates and holds prognostic value in various tumors. The aim of the review and meta-analysis is to assess its prognostic potential and functions in maligna...

journal_title：Journal of Cancer

authors： Zhang Y,Lin S,Yang X,Zhang X

更新日期：2019-02-26 00:00:00

abstract：:The alterations of MET have been detected in non-small-cell lung cancer (NSCLC). However, the prognostic impact of MET gene copy number gain (CNG) has not been consistent among studies. We performed this meta-analysis to evaluate the prognostic value of high MET CNG in patients with NSCLC. A systematic computerized se...

journal_title：Journal of Cancer

authors： Kim JH,Kim HS,Kim BJ

更新日期：2018-04-23 00:00:00

abstract：:Background: The effect of adjuvant chemotherapy on stage II colon cancer remains constantly controversial. Recently, however, several studies have reported the definite survival benefit of adjuvant chemotherapy (ACT) in T4 disease (stage IIB and IIC) among stage II colon cancer patients. The following study investigat...

journal_title：Journal of Cancer

authors： Liu Q,Luo D,An H,Zhang S,Cai S,Li Q,Li X

更新日期：2019-01-29 00:00:00

abstract：:Studies have indicated the significance of tumor associated macrophages (TAMs) in breast cancer; however, inconsistent results still exist. We retrospectively reviewed the macrophage distribution in 1579 breast cancer specimens with anti-CD68 or anti-CD163 immunohistochemical staining, and further analyzed the overall...

journal_title：Journal of Cancer

authors： Ni C,Yang L,Xu Q,Yuan H,Wang W,Xia W,Gong D,Zhang W,Yu K

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Heterogeneity of surgical care exists among surgeons regarding the conduct of thyroidectomy and parathyroidectomy. AIM:To identify the current patterns of technical conduct of operation amongst surgeons performing thyroidectomy or parathyroidectomy. METHODS:A survey was designed and beta-tested on five sur...

journal_title：Journal of Cancer

authors： Henry L,Helou L,Solomon N,Chang A,Libutti S,Stojadinovic A

更新日期：2012-01-01 00:00:00