Preoperative Albumin to Globulin Ratio (AGR) as Prognostic Factor in Renal Cell Carcinoma.

abstract：:Purpose: Hypoxia-inducible factor-1alpha (HIF-1A) is a transcription factor that plays an "angiogenic switch" role especially under hypoxia microenvironment in solid tumor. However, the functions and clinical significance of HIF-1A in gallbladder cancer (GBC) are still controversial, and it has not been studied in nor...

journal_title：Journal of Cancer

authors： Wu Y,Meng D,You Y,Sun R,Fu M,Yan Q,Zhang S,Fang Z,Bao J,Li Y

更新日期：2021-01-01 00:00:00

abstract：:Red blood cell distribution width (RDW) has been recently demonstrated to be a predictor of inflammation. High pretreatment RDW level is associated with poor survival outcomes in various malignancies, although the results are controversial. We aimed to investigate the prognostic role of RDW. A systematic literature se...

journal_title：Journal of Cancer

authors： Wang PF,Song SY,Guo H,Wang TJ,Liu N,Yan CX

更新日期：2019-07-10 00:00:00

abstract：PURPOSE:To investigate prognostic impact of chemoradiotherapy-induced hemoglobin (Hb) decrease on treatment outcomes of endemic nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS:Eight hundred and fifteen non-metastatic NPC, receiving neoadjuvant chemotherapy followed by radiotherapy (NACT+RT group) or concomitant ...

journal_title：Journal of Cancer

authors： Liang XX,Li Q,Su Z,Lan XW,Ouyang PY,Mao YP,Shi DB,Deng WG,Cheng ZB,Wang SY,Xie FY

更新日期：2015-04-02 00:00:00

abstract：:Ovarian cancer is a highly lethal malignancy in the female reproductive system. Platinum drugs, represented by cisplatin, are the first-line chemotherapeutic agents for treatment of various malignancies including ovarian cancer, but drug resistance leads to chemotherapy failure. MicroRNAs emerged as promising molecule...

journal_title：Journal of Cancer

authors： Xiang Y,Chen YJ,Yan YB,Liu Y,Qiu J,Tan RQ,Tian Q,Guan L,Niu SS,Xin HW

更新日期：2020-03-13 00:00:00

abstract：BACKGROUND:Medullary thyroid cancer (MTC) commonly presents with lymph node (LN) metastases, and has a worse prognosis than papillary thyroid cancer (PTC). Tumor size and LN involvement have been shown to affect stage of disease; however, to our knowledge, ours is the first study that attempts to correlate anterior nec...

journal_title：Journal of Cancer

authors： Guerrero MA,Lindsay S,Suh I,Vriens MR,Khanafshar E,Shen WT,Gosnell J,Kebebew E,Duh QY,Clark OH

更新日期：2011-04-08 00:00:00

abstract：:Purpose: Diffuse large B cell lymphoma (DLBCL) is one of the most common B cell lymphomas, which displays heterogeneous pathologies. Programmed cell death 1/ programmed cell death ligand 1 (PD-1/PD-L1) plays an essential role in immunosuppression in multiple malignancies. Signal transducer and activator of transcripti...

journal_title：Journal of Cancer

authors： Fei Y,Yu J,Li Y,Li L,Zhou S,Zhang T,Li L,Qiu L,Meng B,Pan Y,Ren X,Qian Z,Wang X,Zhang H

更新日期：2020-10-17 00:00:00

abstract：OBJECTIVE:To elucidate the oncologic behavior of Micropapillary Urothelial Bladder Carcinoma (MPBC), a rare aggressive variant histology. METHODS:All MPBC patients in SEER 17 database were compared with those with traditional urothelial carcinoma (UC). Kaplan-Meier curves were used to determine OS and CSS. A Cox propo...

journal_title：Journal of Cancer

authors： Vourganti S,Harbin A,Singer EA,Shuch B,Metwalli AR,Agarwal PK

更新日期：2013-05-06 00:00:00

abstract：PURPOSE:Urothelial carcinoma (UC) is a type of tumor, especially of the urinary bladder, that affects people worldwide. Clarification of its detailed tumor biology and discovery of potential targets for developing treatment strategies are imperative because of frequent recurrences and poor prognosis of advanced UCs. By...

journal_title：Journal of Cancer

authors： Chang IW,Li CF,Lin VC,He HL,Liang PI,Wu WJ,Li CC,Huang CN

更新日期：2016-07-08 00:00:00

abstract：:Background and aim: Understanding the molecular biological mechanisms underlying laryngeal squamous cell carcinoma (LSCC) invasion and metastasis is crucial for diagnosis, treatment, and prognosis. We aimed to examine the expression of the tumor suppressor microRNA-204-5p (miR-204-5p) and its target gene, forkhead box...

journal_title：Journal of Cancer

authors： Gao W,Wu Y,He X,Zhang C,Zhu M,Chen B,Liu Q,Qu X,Li W,Wen S,Wang B

更新日期：2017-07-21 00:00:00

abstract：:Background/Aims: Autologous, tumor-derived, heat shock protein gp96 peptide complexes have antitumor potential. We conducted the first Phase II trial to evaluate the safety and efficacy of gp96 vaccination in adjuvant settings for patients with gastric cancer. Methods: We enrolled 73 consecutive patients from October ...

journal_title：Journal of Cancer

authors： Zhang K,Peng Z,Huang X,Qiao Z,Wang X,Wang N,Xi H,Cui J,Gao Y,Huang X,Gao H,Wei B,Chen L

更新日期：2017-07-02 00:00:00

abstract：:Objective: As a member of the N-myc downregulated gene family, N-Myc downstream-regulated gene 2 (NDRG2) contributes to tumorigenesis of various types of cancer. The expression status of NDRG2 in colorectal cancer (CRC) and its prognostic value remain to be elucidated. The goal of this study was to determine the expre...

journal_title：Journal of Cancer

authors： Chen W,Peng J,Ou Q,Wen Y,Jiang W,Deng Y,Zhao Y,Wan D,Pan Z,Fang Y

更新日期：2019-06-09 00:00:00

abstract：:Objective: To investigate the development of bronchoscopy in China and compare it with its application in the early 21st century. Methods: The data collection was based on questionnaires. Three hundred and nineteen hospitals, which distributed across 30 provinces and 130 cities, were included in the study. Data about ...

journal_title：Journal of Cancer

authors： Shi D,Li F,Wang K,Kong C,Huang H,Li Q,Jin F,Hu C,Wang C,Shi H,Hu Z,Dong Y,Ning Y,Tsakiridis K,Sapalidis K,Kosmidis C,Vagionas A,Hohenforst-Schmidt W,Freitag L,Turner JF,Drevelegas K,Perdikouri EI,Kovacevic T,

更新日期：2020-07-20 00:00:00

abstract：:Background: Regulatory T cells (Tregs) and plasmacytoid dendritic cells (pDCs) are the main immunosuppressive cells in tumor microenvironment of gastric cancer (GC). In this prospective study, the association of prognosis with Tregs subsets and pDCs were further analyzed. Methods: pDCs, Tregs population and its expres...

journal_title：Journal of Cancer

authors： Liu X,Yu H,Yan C,Mei Y,Lin C,Hong Y,Lin X,Zhang Q,Yu J

更新日期：2019-10-22 00:00:00

abstract：:Background: The most common metastatic site in cervical cancers is lung. The aim of this study is to identify cervical cancer patients with high risk for developing lung metastasis and further explore their prognosis. Materials and Methods: At first, patients diagnosed with cervical cancer from 2010 to 2015 were ident...

journal_title：Journal of Cancer

authors： Chen X,Chen L,Zhu H,Tao J

更新日期：2020-08-08 00:00:00

abstract：:Background: To investigate the relationship between clinical and histopathological characteristics and overall survival of patients with oral mucosal melanoma (OMM) without distal metastasis in order to provide predictive prognostic information of OMM. Methods: Ki67 expression was assessed by immunohistochemistry in 1...

journal_title：Journal of Cancer

authors： Ma X,Wu Y,Zhang T,Song H,Jv H,Guo W,Ren G

更新日期：2017-10-17 00:00:00

abstract：:Background: The Matrix metalloproteinase-14 (MMP-14) expression has been shown to be overexpressed in different cancers. However, there is no comprehensive quantitative evaluation of the MMP-14 prognostic value in digestive system carcinoma (DSC). The aim of this study is to explore the correlation between the MMP-14 ...

journal_title：Journal of Cancer

authors： Duan F,Peng Z,Yin J,Yang Z,Shang J

更新日期：2020-01-01 00:00:00

abstract：:Purpose: Extremity soft tissue leiomyosarcoma (LMS) with metastasis is a rare disease with a poor prognosis. The purpose of our study was to define clinical features of extremity soft tissue LMS with metastasis as well as to identify multivariable predictors of survival. Methods: During 1973-2015, 239 patients with me...

journal_title：Journal of Cancer

authors： Qian SJ,Wu JQ,Wang Z,Zhang B

更新日期：2019-05-21 00:00:00

abstract：:For unresectable Hepatocellular carcinoma (HCC), chemotherapy is still an important treatment strategy. Oxaliplatin (Oxa) is an effective treatment of HCC after sorafenib treatment failure. However, the intrinsic or acquired resistance of Oxa affected the chemotherapeutic sensitivity. By analyzing the data of GEO Data...

journal_title：Journal of Cancer

authors： Tao Y,Shan L,Xu X,Jiang H,Chen R,Qian Z,Yang Z,Liang B,Zheng H,Cai F,Yu Y,Ma L

更新日期：2018-10-10 00:00:00

abstract：:Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy from surgery, chemotherapy, to radiotherapy. Efforts in recent decades have brought many novel therapies to light, however, with limitations. In...

journal_title：Journal of Cancer

authors： Zhang H,Wang R,Yu Y,Liu J,Luo T,Fan F

更新日期：2019-08-27 00:00:00

abstract：:Purpose Neuroblastoma is an embryonic solid tumor derived from the progenitors of the sympathetic nervous system. More than half of the patients developed metastatic disease at the time of initial diagnosis and had poor outcome with current therapeutic approaches. In recent years, some obligate and facultative anaerob...

journal_title：Journal of Cancer

authors： Ning BT,Yu B,Chan S,Chan JL,Huang JD,Chan GC

更新日期：2017-06-03 00:00:00

abstract：:Minichromosome Maintenance (MCM) proteins play essential roles in various cancers. We previously reported that MCM7 could be a prognostic biomarker in non-small cell lung cancer (NSCLC). The purpose of current study is to explore roles of other MCM proteins in NSCLC and their correlation with clinico-pathologic parame...

journal_title：Journal of Cancer

authors： Liu YZ,Wang BS,Jiang YY,Cao J,Hao JJ,Zhang Y,Xu X,Cai Y,Wang MR

更新日期：2017-10-09 00:00:00

abstract：:There is limited literature documenting granulocytic sarcoma of the colon. We report a case of a 28 year-old female with a colonic granulocystic sarcoma of the colon as a complication of AML, as it is an important consideration with surgical management of typhilitis. ...

journal_title：Journal of Cancer

authors： Tsikitis VL,Corning C,Henderson J,Rose J

更新日期：2010-07-14 00:00:00

abstract：:Recent studies indicated that long noncoding RNAs (lncRNAs) played important regulatory roles in carcinogenesis and cancer progression. However, the contribution of small nucleolar RNA host gene 20 (SNHG20) to cancer development remains largely unknown. The aim of the study is to investigate the expression of SNHG20 a...

journal_title：Journal of Cancer

authors： Zhang D,Cao C,Liu L,Wu D

更新日期：2016-03-19 00:00:00

abstract：:Background: Programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) is considered as a predictive biomarker of anti-PD-1/PD-L1 cancer therapies. However, the correlation of PD-L1 expression status between the primary and paired metastatic NSCLC is still not clear. The current study aims to a...

journal_title：Journal of Cancer

authors： Luo L,Luo X,Chen W,Liang C,Yao S,Huang W,Liu C,Ge Y,Lin X,Li Z

更新日期：2020-01-01 00:00:00

abstract：:Centromere protein N (CENP-N), an important member of the centromere protein family, is essential for kinetochore assembly and chromosome segregation; however, the relevance of CENP-N in cancers remains unknown. The aim of this study was to investigate CENP-N expression and its functional mechanisms in oral squamous c...

journal_title：Journal of Cancer

authors： Oka N,Kasamatsu A,Endo-Sakamoto Y,Eizuka K,Wagai S,Koide-Ishida N,Miyamoto I,Iyoda M,Tanzawa H,Uzawa K

更新日期：2019-06-09 00:00:00

abstract：OBJECTIVE(S):To assess skeletal wide fracture location and time of fracture after cancer treatment Study Design: One hundred thirty-nine women diagnosed with breast or gynecologic cancer between 2003 and 2012 that subsequently had a radiologic diagnosis of fracture were identified retrospectively using electronic medic...

journal_title：Journal of Cancer

authors： Hui SK,Arentsen L,Wilcox A,Shanley R,Yee D,Ghebre R

更新日期：2015-01-01 00:00:00

abstract：:Background: To develop and validate a radiomic nomogram incorporating radiomic features with clinical variables for individual local recurrence risk assessment in nasopharyngeal carcinoma (NPC) patients before initial treatment. Methods: One hundred and forty patients were randomly divided into a training cohort (n = ...

journal_title：Journal of Cancer

authors： Zhang L,Zhou H,Gu D,Tian J,Zhang B,Dong D,Mo X,Liu J,Luo X,Pei S,Dong Y,Huang W,Chen Q,Liang C,Lian Z,Zhang S

更新日期：2019-07-10 00:00:00

abstract：:Many preclinical and clinical studies are currently evaluating metformin in combination with classical therapeutic agents as anti-cancer therapy. In this study we used three distinct pancreatic cancer cell lines and evaluated cell death by trypan blue assay and Western Blots using antibodies directed against cleaved c...

journal_title：Journal of Cancer

authors： Zechner D,Albert AC,Bürtin F,Vollmar B

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:This study was performed to assess the impact of irradiation on the tissue penetration depth of doxorubicin delivered during Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC). METHODS:Fresh post mortem swine peritoneum was cut into 10 proportional sections. Except for 2 control samples, all received...

journal_title：Journal of Cancer

authors： Khosrawipour V,Giger-Pabst U,Khosrawipour T,Pour YH,Diaz-Carballo D,Förster E,Böse-Ribeiro H,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-05-07 00:00:00

abstract：:Background: Overall survival of patients with primary CNS lymphoma (PCNSL) has improved since the introduction of immunochemotherapy. However, up to 10-15% of PCNSL patients still die shortly after diagnosis. In the present study, we aimed to investigate the risk factors of early mortality (death within 60 days after ...

journal_title：Journal of Cancer

authors： Lin CH,Yang CF,Yang HC,Fay LY,Yeh CM,Kuan AS,Wang HY,Gau JP,Hsiao LT,Chiou TJ,Chen PM,Liu YC,Ko PS,Liu JH,Liu CJ

更新日期：2019-07-05 00:00:00