Prognostic and Clinicopathological Significance of lncRNA MVIH in Cancer Patients.

abstract：:Thyroid transcription factor-1 (TTF-1) is overexpressed in up to 95% of primary lung adenocarcinoma while negative for almost all squamous cell carcinomas. TTF-1 expression has been investigated as a prognostic factor in non-small-cell lung cancer (NSCLC) with conflicting results. We conducted this meta-analysis to ga...

journal_title：Journal of Cancer

authors： Kim JH,Kim HS,Kim BJ,Han B,Choi DR,Kwon JH

更新日期：2018-10-20 00:00:00

abstract：:Cancer is a leading cause of death throughout the world, and cancer therapy remains a big medical challenge in terms of both its therapeutic efficacy and safety. Therefore, to find out a safe anticancer drug has been long goal for oncologist and medical scientists. Among clinically used medicines with no or little tox...

journal_title：Journal of Cancer

authors： Lian X,Wang G,Zhou H,Zheng Z,Fu Y,Cai L

更新日期：2018-04-06 00:00:00

abstract：:Background and aims. Cyclin-dependent kinase inhibitor 3 (CDKN3) has been found playing a varying role in carcinogenesis, but its biological function in esophageal squamous cell carcinoma (ESCC) is unclear. The aim of this study was to demonstrate the role of CDKN3 in ESCC. Materials and Methods: Real-time PCR and Wes...

journal_title：Journal of Cancer

authors： Liu J,Min L,Zhu S,Guo Q,Li H,Zhang Z,Zhao Y,Xu C,Zhang S

更新日期：2019-04-21 00:00:00

abstract：:For many years, the medical treatment of breast cancer was reliant solely on cytotoxic chemotherapy. However, over the past twenty years, treatment has evolved to a more target-directed approach. We now employ tailored therapy based on the presence or absence of receptors for estrogen, progesterone, and human epiderma...

journal_title：Journal of Cancer

authors： Tinoco G,Warsch S,Glück S,Avancha K,Montero AJ

更新日期：2013-01-01 00:00:00

abstract：:Background: To support cancer therapy, development of low cost library preparation techniques for targeted next generation sequencing (NGS) is needed. In this study we designed and tested a PCR-based library preparation panel with limited target area for sequencing the top 12 somatic mutation hot spots in colorectal c...

journal_title：Journal of Cancer

authors： Péterfia B,Kalmár A,Patai ÁV,Csabai I,Bodor A,Micsik T,Wichmann B,Egedi K,Hollósi P,Kovalszky I,Tulassay Z,Molnár B

更新日期：2017-01-12 00:00:00

abstract：:[This retracts the article DOI: 10.7150/jca.29953.]. ...

journal_title：Journal of Cancer

authors： Qu J,Cheng T,Liu L,Heng J,Liu X,Sun Z,Wang W,Li K,Yang N

更新日期：2019-09-02 00:00:00

abstract：:Background: HER2 serves as an important therapeutic target in gastroesophageal cancer. Differences in HER2 gene signal distribution patterns can be observed at the tissue level, but how it influences the HER2 amplification status has not been studied so far. Here, we investigated the link between HER2 amplification an...

journal_title：Journal of Cancer

authors： Jørgensen JT,Nielsen KB,Kjærsgaard G,Jepsen A,Mollerup J

更新日期：2017-06-01 00:00:00

abstract：:Purpose: To evaluate long-term survival trends after primary total laryngectomy (TL) for locally advanced laryngeal carcinoma (LC). Methods: A total of 2094 patients diagnosed with locally advanced LC and underwent primary TL (1992-2011, at least 5-year follow-up) in the Surveillance, Epidemiology, and End Results (SE...

journal_title：Journal of Cancer

authors： Lin Z,Lin H,Chen Y,Xu Y,Chen X,Fan H,Wu X,Ke X,Lin C

更新日期：2021-01-01 00:00:00

abstract：:Background: Cancers may arise from cells with dysregulated telomeric functions due to shorten telomere length. We and others previously found that short leukocyte telomere length was associated with markedly evaluated risk of esophageal squamous cell carcinoma (ESCC). Hence, we hypothesized that single nucleotide poly...

journal_title：Journal of Cancer

authors： Li Z,Song Y,Xu Y,Shen Y,Zhang N,Yang M,Yu D

更新日期：2020-06-23 00:00:00

abstract：:Objective: To investigate the development of bronchoscopy in China and compare it with its application in the early 21st century. Methods: The data collection was based on questionnaires. Three hundred and nineteen hospitals, which distributed across 30 provinces and 130 cities, were included in the study. Data about ...

journal_title：Journal of Cancer

authors： Shi D,Li F,Wang K,Kong C,Huang H,Li Q,Jin F,Hu C,Wang C,Shi H,Hu Z,Dong Y,Ning Y,Tsakiridis K,Sapalidis K,Kosmidis C,Vagionas A,Hohenforst-Schmidt W,Freitag L,Turner JF,Drevelegas K,Perdikouri EI,Kovacevic T,

更新日期：2020-07-20 00:00:00

abstract：:Background and Aim: Glioblastoma multiforme (GBM) is a highly aggressive brain malignancy that lacks reliable treatments. Resveratrol possesses anti-cancer effects, but its activity against glioblastoma cells is variable for unknown reasons. One mechanism through which anti-cancer drugs exert their effects is oxidativ...

journal_title：Journal of Cancer

authors： Jia B,Zheng X,Wu ML,Tian XT,Song X,Liu YN,Li PN,Liu J

更新日期：2021-01-01 00:00:00

abstract：:The purpose of this study was to determine the association between body mass index (BMI) measurements (baseline BMI and changes in BMI during neoadjuvant systemic treatment [NST]) and clinical efficacy (pathologic complete response [pCR] rate and survival outcomes) in locally advanced breast cancer (LABC). We hypothes...

journal_title：Journal of Cancer

authors： Kogawa T,Fouad TM,Wei C,Masuda H,Kai K,Fujii T,El-Zein R,Chavez-MacGregor M,Litton JK,Brewster A,Alvarez RH,Hortobagyi GN,Valero V,Theriault R,Ueno NT

更新日期：2015-01-22 00:00:00

abstract：BACKGROUND:MALAT-1 is significantly overexpressed in various cancers, suggesting that it might be a potential biomarker of cancer. METHODS:A meta-analysis was performed using microarray data obtained via the Affymetrix Human Genome U133 Plus 2.0 platform found in the Gene Expression Omnibus (GEO) database and data obt...

journal_title：Journal of Cancer

authors： Wang Y,Xue D,Li Y,Pan X,Zhang X,Kuang B,Zhou M,Li X,Xiong W,Li G,Zeng Z,Yang T

更新日期：2016-05-20 00:00:00

abstract：:Endometrial carcinoma (EC) is the most common malignant tumors in female derived from the endometrial epithelium. Several previous studies have described estrogen receptors (ER), progesterone Receptor (PR) and phosphatase and tensin homolog (PTEN) are associated with clinicopathological factors and prognosis in EC pat...

journal_title：Journal of Cancer

authors： Liang Y,Lin B,Ye Z,Chen S,Yu H,Chen C,Zhang X,Zhou K,Zeng J

更新日期：2020-01-13 00:00:00

abstract：:In 2006, a remarkable collaboration between University of Texas MD Anderson Cancer Center clinicians and Texas and New Mexico State legislators led to the formation of a dedicated IBC Research Program and Clinic at MD Anderson. This initiative provided funding and infrastructure to foster coordination of an IBC World ...

journal_title：Journal of Cancer

authors： Woodward WA,Cristofanilli M,Merajver SD,Van Laere S,Pusztai L,Bertucci F,Berditchevski F,Polyak K,Overmoyer B,Devi GR,Sterneck E,Schneider R,Debeb BG,Wang X,van Golen KL,El-Zein R,Rahal OM,Alexander A,Reuben JM,Kris

更新日期：2017-10-09 00:00:00

abstract：:Cancer cells express epithelial markers, and when progressing in malignancy they may express markers of the mesenchymal cell type. Therefore an epithelial-mesenchymal transition of the cancer cells is assumed. However the mesenchymal markers can equally well be interpreted as myeloid markers since they are common in b...

journal_title：Journal of Cancer

authors： Schramm HM

更新日期：2014-01-15 00:00:00

abstract：:Our results show that using an EBV-LCL feeder cell line, large numbers of pure populations of highly activated NK cells can be expanded ex vivo under GMP conditions. With the exception of thyroiditis and constitutional symptoms related to IL-2 therapy, infusions of up to 1 x 10(8) cells/kg of ex vivo expanded NK have ...

journal_title：Journal of Cancer

authors： Lundqvist A,Berg M,Smith A,Childs RW

更新日期：2011-01-01 00:00:00

abstract：:Background: The incidence and mortality rate of gastric cancer has markedly declined over the past few decades, due to the progress and advances in the development of diagnostic and treatment regimens. However, there is still a large portion of patients who are first diagnosed during the advanced stage of gastric canc...

journal_title：Journal of Cancer

authors： Si W,Lyu J,Liu Z,Wang C,Huang J,Jiang L,Ma T

更新日期：2019-10-06 00:00:00

abstract：:Background: IgA antibodies against Epstein-Barr virus (EBV) capsid antigen (VCA) and nuclear antigen 1 (EBNA1) have been proposed to facilitate the diagnosis and early detection of nasopharyngeal carcinoma (NPC) in high-incidence regions. However, while new methodologies and new platforms for the detection of VCA-IgA ...

journal_title：Journal of Cancer

authors： Yu X,Li F,Cheng W,Wu B,Fang H,Xia F,Gong Y,Yu W,Liao P,Cao Y,Yang F,Zhu H,Li J,Huang Y,Gan L,Zhang L,Lou Y,Ji M

更新日期：2020-10-18 00:00:00

abstract：:Breast cancer is considered as a heterogeneous disease comprising various types of neoplasms, which involves different profile changes in both mRNA and micro-RNA (miRNA) expression. Extensive studies on mRNA expression in breast tumor have yielded some very interesting findings, some of which have been validated and u...

journal_title：Journal of Cancer

authors： Fu SW,Chen L,Man YG

更新日期：2011-02-24 00:00:00

abstract：:Chemotherapy resistance represents a major obstacle for the treatment of patients with breast cancer (BC) and greatly restricts the therapeutic effect of the first-line chemotherapeutic agent doxorubicin (DOX). The present study aimed to investigate the feasibility of the recombinant dual-target murine double minute 2...

journal_title：Journal of Cancer

authors： Fan Y,Ma K,Jing J,Wang C,Hu Y,Shi Y,Li E,Geng Q

更新日期：2020-01-01 00:00:00

abstract：:Background: Malignant biliary and/or pancreatic obstruction has often encountered in the advanced stages of periampullary and cholangicarcinomas. HabibTM Radiofrequency (RF) ablation has been successfully used in the management of various cancers of liver and pancreas. Percutaneous HPB probe (EMcision Ltd, London, UK)...

journal_title：Journal of Cancer

authors： Mizandari M,Kumar J,Pai M,Chikovani T,Azrumelashvili T,Reccia I,Habib N

更新日期：2018-01-05 00:00:00

abstract：:RBP7 is a member of the cellular retinol-binding protein (CRBP) family and previous data suggested a link between CRBPs and the malignant transformation of colon cancer cells. Here, we investigated the potential of RBP7 as a predictive biomarker for patients with colon cancer and determined its functional relevance fo...

journal_title：Journal of Cancer

authors： Elmasry M,Brandl L,Engel J,Jung A,Kirchner T,Horst D

更新日期：2019-08-27 00:00:00

abstract：:Objectives: To investigate the role of inflammation-related factors, lymphocyte-to-monocyte ratio (LMR) alone and combined detection with cancer antigen 125 (CA125), in the prognostic assessment of ovarian cancer (OC). Methods: A retrospective clinicopathologic review was performed. The receiver-operating characterist...

journal_title：Journal of Cancer

authors： Tang Y,Hu HQ,Tang FX,Lin D,Shen R,Deng L,Tang YL,Deng LH,Zhou M,Li J,Su B,Xu F

更新日期：2020-03-04 00:00:00

abstract：UNLABELLED:The mechanism of progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) remains largely unknown. We compared gene expression in tumors with simultaneous DCIS and IDC to decipher how diverse proteins participate in the local invasive process.Twenty frozen tumor specimens with conc...

journal_title：Journal of Cancer

authors： Castellana B,Escuin D,Peiró G,Garcia-Valdecasas B,Vázquez T,Pons C,Pérez-Olabarria M,Barnadas A,Lerma E

更新日期：2012-01-01 00:00:00

abstract：:Background: Neoadjuvant chemoradiation (CRT) remains controversial in the treatment of the oesophagus or gastro-oesophageal junction (GOJ) carcinomas. Methods: We conducted a meta-analysis to assess the efficacy and safety of Neoadjuvant CRT plus surgery comparing with neoadjuvant CT plus surgery or surgery alone. Fea...

journal_title：Journal of Cancer

authors： Meng X,Wang L,Zhao Y,Zhu B,Sun T,Zhang T,Gu X,Zheng Z

更新日期：2019-01-01 00:00:00

abstract：:Background: miRNAs dysregulate in hepatocellular carcinoma (HCC), showing promise for diagnostic biomarkers which may be found through exploration of differentially expressed miRNAs when comparing HCC and normal liver tissues. Materials and Methods: In the present research, candidate miRNAs were selected and verified ...

journal_title：Journal of Cancer

authors： Ji J,Chen H,Liu XP,Wang YH,Luo CL,Zhang WW,Xie W,Wang FB

更新日期：2018-09-08 00:00:00

abstract：:Glioblastoma (GBM) is a common malignant brain tumor of the central nervous system with a poor prognosis. In order to identify the prognostic signatures of GBM, we screened differentially expressed genes (DEGs) that were based on a single-cell RNA sequencing (scRNA-seq) dataset. These genes characteristically represen...

journal_title：Journal of Cancer

authors： Liu H,Yang Q,Xiong Y,Xiong Z,Li X

更新日期：2020-04-06 00:00:00

abstract：:Background/Purpose: In colon cancer (CC) patients preoperative (pre-op) levels of VEGF-A165 (VEGF) is a strong predictor for disease recurrence. Elevated postoperative (post-op) VEGF levels could have undesirable effects by enhancing tumor growth and metastasis formation. It has been suggested that thromboprophylaxis ...

journal_title：Journal of Cancer

authors： Mitsis M,Koliou P,Bali C,Ntounousi E,Tatsis V,Nousias V,Lianos GD,Vartholomatos G,Nastos D

更新日期：2017-08-25 00:00:00

abstract：:Background: Epithelial-mesenchymal transition (EMT) plays an important role in the invasion and migration during cancer metastasis. Wnt3a is one of the ligands in canonical Wnt/β-catenin signaling pathway, which contributes to the carcinogenesis and progression of lung cancer cell lines. The aim of this study was to e...

journal_title：Journal of Cancer

authors： Xu J,Lv W,Hu Y,Wang L,Wang Y,Cao J,Hu J

更新日期：2017-08-02 00:00:00