听力与言语-语言病理学

行为科学

医学伦理学

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  • The Essential Factors of Establishing Patient-derived Tumor Model.

    abstract::Establishing an applicable preclinical model is vital for translational cancer research. Patient-derived xenograft has been important preclinical model systems and widely used for cancer research. Patient-derived xenograft models that represent the tumors of the patients are necessary to better translate research disc...

    journal_title:Journal of Cancer

    pub_type: 杂志文章,评审

    doi:10.7150/jca.51749

    authors: Chen C,Lin W,Huang Y,Chen X,Wang H,Teng L

    更新日期:2021-01-01 00:00:00

  • Increased Reactive Oxygen Species and Distinct Oxidative Damage in Resveratrol-suppressed Glioblastoma Cells.

    abstract::Background and Aim: Glioblastoma multiforme (GBM) is a highly aggressive brain malignancy that lacks reliable treatments. Resveratrol possesses anti-cancer effects, but its activity against glioblastoma cells is variable for unknown reasons. One mechanism through which anti-cancer drugs exert their effects is oxidativ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.45489

    authors: Jia B,Zheng X,Wu ML,Tian XT,Song X,Liu YN,Li PN,Liu J

    更新日期:2021-01-01 00:00:00

  • Down-regulation of ACACA suppresses the malignant progression of Prostate Cancer through inhibiting mitochondrial potential.

    abstract::Background and aim: Silencing the expression of ACACA inhibits cell proliferation and induces apoptosis in prostate cancer LNCaP cells. However, the role of ACACA in other prostate cancer cells is not fully understood. Also, the effect of knocking down ACACA gene on mitochondria remains unclear. This study aimed to di...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.49560

    authors: Zhang H,Liu S,Cai Z,Dong W,Ye J,Cai Z,Han Z,Liang Y,Zhuo Y,Luo Y,Zhu X,Deng Y,Zhang Y,Liu R,Feng Y,Lai J,Zhou R,Tan H,Zhong W

    更新日期:2021-01-01 00:00:00

  • A New Method for the Detection of Colorectal Cancer and the Precancerous Lesions: Occult Blood Testing Combination with Promoter Methylation in the Fecal Sample.

    abstract::Background: Noninvasive stool-based DNA methylation testing emerges as a new approach for detecting colorectal cancer (CRC). However, its feasibility for early detection of CRC and precancerous lesions in the Chinese population remains inconclusive. Methods: In this study, we establish a possibilities screening method...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.50525

    authors: Wang DY,He KX,Huang Y,Lou QQ,He T,Xu X

    更新日期:2021-01-01 00:00:00

  • Whole-exome Sequencing of Prostate Cancer in Sardinian Identify Recurrent UDP-glucuronosyltransferase Amplifications.

    abstract::Globally, prostate cancer is the third most common cancer in the world, and the second most common cancer in men. However, rates for incidence and mortality vary considerably with race, ethnicity, and geography. Over 97 significantly mutated genes that have been identified in prostate cancer; however, a lack of genomi...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.48433

    authors: Zeng T,Fedeli MA,Tanda F,Wang Y,Yang D,Xue B,Jia L,Palmieri G,Sechi LA,Kelvin DJ

    更新日期:2021-01-01 00:00:00

  • Can Patients with Pancreatic Cancer and Liver Metastases Obtain Survival Benefit from Surgery? A Population-Based Study.

    abstract::Background: Surgery for pancreatic cancer with liver metastases (PCL) is not recommended in the international guidelines, and investigation of its clinical significance in patients with PCL is very limited. This study explored whether surgery, especially synchronous resection of the primary tumor and liver metastases ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.51218

    authors: Su BB,Bai DS,Yu JQ,Zhang C,Jin SJ,Zhou BH,Jiang GQ

    更新日期:2021-01-01 00:00:00

  • MRI-Based Radiomic Model for Preoperative Risk stratification in Stage I Endometrial Cancer.

    abstract::Introduction: Preoperative risk stratification is crucial for clinical treatment of endometrial cancer (EC). This study aimed to establish a model based on magnetic resonance imaging (MRI) and clinical factors for risk classification of EC. Materials and Methods: A total of 102 patients with pathologically proven Stag...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.50872

    authors: Chen J,Gu H,Fan W,Wang Y,Chen S,Chen X,Wang Z

    更新日期:2021-01-01 00:00:00

  • Hypoxia Inducible Factor-1alpha (HIF-1A) plays different roles in Gallbladder Cancer and Normal Gallbladder Tissues.

    abstract::Purpose: Hypoxia-inducible factor-1alpha (HIF-1A) is a transcription factor that plays an "angiogenic switch" role especially under hypoxia microenvironment in solid tumor. However, the functions and clinical significance of HIF-1A in gallbladder cancer (GBC) are still controversial, and it has not been studied in nor...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46749

    authors: Wu Y,Meng D,You Y,Sun R,Fu M,Yan Q,Zhang S,Fang Z,Bao J,Li Y

    更新日期:2021-01-01 00:00:00

  • Novel biomarkers and prediction model for the pathological complete response to neoadjuvant treatment of triple-negative breast cancer.

    abstract::Objective: To develop and validate a prediction model for the pathological complete response (pCR) to neoadjuvant chemotherapy (NCT) of triple-negative breast cancer (TNBC). Methods: We systematically searched Gene Expression Omnibus, ArrayExpress, and PubMed for the gene expression profiles of operable TNBC accessibl...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.52439

    authors: Han Y,Wang J,Xu B

    更新日期:2021-01-01 00:00:00

  • EHMT2 inhibitor BIX-01294 induces endoplasmic reticulum stress mediated apoptosis and autophagy in diffuse large B-cell lymphoma cells.

    abstract::Despite advancement in the treatment of diffuse large B-cell lymphoma (DLBCL), many patients tend to relapse or become refractory after initial therapy. Therefore, it is essential to identify novel therapeutic targets and drugs, understand the molecular pathogenesis mechanism of DLBCL, and find ways to prevent and tre...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.48310

    authors: Xu L,Gao X,Yang P,Sang W,Jiao J,Niu M,Liu M,Qin Y,Yan D,Song X,Sun C,Tian Y,Zhu F,Sun X,Zeng L,Li Z,Xu K

    更新日期:2021-01-01 00:00:00

  • GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer.

    abstract::Cachexia is a metabolic mutiny that directly reduces life expectancy in chronic conditions such as cancer. The underlying mechanisms associated with cachexia involve inflammation, metabolism, and anorexia. Therefore, the need to identify cachexia biomarkers is warranted to better understand catabolism change and asses...

    journal_title:Journal of Cancer

    pub_type: 杂志文章,评审

    doi:10.7150/jca.50376

    authors: Ahmed DS,Isnard S,Lin J,Routy B,Routy JP

    更新日期:2021-01-01 00:00:00

  • Long-term survival trend after primary total laryngectomy for patients with locally advanced laryngeal carcinoma.

    abstract::Purpose: To evaluate long-term survival trends after primary total laryngectomy (TL) for locally advanced laryngeal carcinoma (LC). Methods: A total of 2094 patients diagnosed with locally advanced LC and underwent primary TL (1992-2011, at least 5-year follow-up) in the Surveillance, Epidemiology, and End Results (SE...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.50404

    authors: Lin Z,Lin H,Chen Y,Xu Y,Chen X,Fan H,Wu X,Ke X,Lin C

    更新日期:2021-01-01 00:00:00

  • Characteristics and differences of gut microbiota in patients with different Traditional Chinese Medicine Syndromes of Colorectal Cancer and normal population.

    abstract::Colorectal cancer (CRC) is considered to be closely associated with alteration of intestinal microorganisms. The purpose of present study was to investigate the distribution of gut microbiota in the distinction of microbiota dysbiosis between two disease syndromes called Zheng-Qi-Kui-Xu(ZQKX) and Xie-Du-Yong-Sheng (XD...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.50318

    authors: Wang P,Ding S,Sun L,Feng Y,Guo K,Zhu Y,Huang D,Ruan S

    更新日期:2020-10-23 00:00:00

  • Fibroblast growth factor receptor signaling as therapeutic targets in female reproductive system cancers.

    abstract::Ovarian cancer, cervical cancer and endometrial cancer are three relatively common malignant cancers of the female reproductive system. Despite improvements in female genital tract cancer detection and development of new therapeutic approaches, there are still poor prognoses and some do not respond to therapeutic patt...

    journal_title:Journal of Cancer

    pub_type: 杂志文章,评审

    doi:10.7150/jca.44727

    authors: Zhu DL,Tuo XM,Rong Y,Zhang K,Guo Y

    更新日期:2020-10-21 00:00:00

  • Efficacy of Chemiluminescence Immunoassays on VCA-IgA and EBNA1-IgA Antibodies of Epstein-Barr Virus in Diagnosing Nasopharyngeal Carcinoma.

    abstract::Background: IgA antibodies against Epstein-Barr virus (EBV) capsid antigen (VCA) and nuclear antigen 1 (EBNA1) have been proposed to facilitate the diagnosis and early detection of nasopharyngeal carcinoma (NPC) in high-incidence regions. However, while new methodologies and new platforms for the detection of VCA-IgA ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.47260

    authors: Yu X,Li F,Cheng W,Wu B,Fang H,Xia F,Gong Y,Yu W,Liao P,Cao Y,Yang F,Zhu H,Li J,Huang Y,Gan L,Zhang L,Lou Y,Ji M

    更新日期:2020-10-18 00:00:00

  • Plasma soluble PD-L1 and STAT3 predict the prognosis in diffuse large B cell lymphoma patients.

    abstract::Purpose: Diffuse large B cell lymphoma (DLBCL) is one of the most common B cell lymphomas, which displays heterogeneous pathologies. Programmed cell death 1/ programmed cell death ligand 1 (PD-1/PD-L1) plays an essential role in immunosuppression in multiple malignancies. Signal transducer and activator of transcripti...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.47816

    authors: Fei Y,Yu J,Li Y,Li L,Zhou S,Zhang T,Li L,Qiu L,Meng B,Pan Y,Ren X,Qian Z,Wang X,Zhang H

    更新日期:2020-10-17 00:00:00

  • TGF-β1-Induced Upregulation of MALAT1 Promotes Kazakh's Esophageal Squamous Cell Carcinoma Invasion by EMT.

    abstract::Transforming growth factor β1 (TGF-β1) plays an important role in tumor initiation and development by inducing epithelial-mesenchymal Transition (EMT). Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a long noncoding RNA (lncRNA) that contributes to the invasion and metastasis of tumors, including e...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.48426

    authors: Liu Q,Zheng S,Chen Y,Liu T,Han X,Zhang X,Shen T,Lu X

    更新日期:2020-10-04 00:00:00

  • Effect of TTLL6 expression on CDDP sensitivity of EC109/CDDP cells in hypoxia/acidosis microenvironment.

    abstract::Multidrug resistance is a major obstacle to the effective treatment of esophageal carcinoma. It occurs more readily in hypoxia and acidosis microenvironment. TTLL6 is one of Tubulin tyrosine ligase-like family members. In this study, the effect of TTLL6 on the regulation of cisplatin (CDDP) sensitivity was evaluated i...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.47694

    authors: Qiu Y,Wu C,Li J,Tang M,Zhang S,Jing T,Liao Y,Wang H

    更新日期:2020-09-30 00:00:00

  • Biological functions and prognostic value of RNA Binding Proteins in clear cell Renal Cell Carcinoma.

    abstract::Early detection and accurate evaluation were both critical to improving the prognosis of clear cell Renal Cell Carcinoma (ccRCC) patients. More importantly, RNA Binding Proteins (RBPs) play a vital role in the tumorigenesis and progression of numerous cancers. However, the relationship between RBPs and ccRCC is still ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.49175

    authors: Zhu Z,He A,Lin L,Xu C,Cai T,Lin J

    更新日期:2020-09-23 00:00:00

  • Landscape of FGF/FGFR Alterations in 12,372 Chinese Cancer Patients.

    abstract::Purpose: The aberrant of fibroblast growth factors and their receptors (FGF/FGFR) is an emerging target in the treatment of solid tumors. This study aimed to explore the landscape of FGF/FGFR alterations in a large cohort of cancer patients. Material and Methods: The formalin-fixed paraffin-embedded specimens of cance...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.49269

    authors: Zuo W,He Y,Li W,Wu H,Zhao Z,Zhang Y,Chen S,Yin Y

    更新日期:2020-09-23 00:00:00

  • Improved diagnostic value by combining plasma PON1 level with tumor biomarkers in Colorectal Cancer patients.

    abstract::The incidence of colorectal cancer (CRC) ranks third among all cancers in China and improvements in screening for CRC have an important impact on prevention and control of the disease. Paraoxonase 1 (PON1) is a calcium ion-dependent hydrolase that is widely distributed in tissue. Its diagnostic value in colorectal can...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.45204

    authors: Zhang J,Yang X,Wei L,Tan H,Chen J,Li W,Chan K,Su Y,Zhao L,Hu S,Zhong S,Xiao Y,Liu H

    更新日期:2020-09-17 00:00:00

  • Long-term aspirin use for primary cancer prevention: An updated systematic review and subgroup meta-analysis of 29 randomized clinical trials.

    abstract::Background and objective: Long-term aspirin use for the primary prevention of cancer remains controversial, and variations in the effect of aspirin use on cancer outcomes by aspirin dose, follow-up duration, or study population have never been systematically evaluated. The objective of this study was to evaluate the e...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.49001

    authors: Wu Q,Yao X,Chen H,Liu Z,Li T,Fan X,Zhang G,Yu L,Chen M,Xu C,Zhang R,Chen B,Sui X,Leung EL

    更新日期:2020-09-14 00:00:00

  • Identification of CTLA-4 associated with tumor microenvironment and competing interactions in triple negative breast cancer by co-expression network analysis.

    abstract::Background: The study of CTLA-4 inhibitors has been one of the hot spots in the field of tumor immunotherapy. As the most immunogenic subtype of breast cancer, Triple negative breast cancer (TNBC) has a great potential in the treatment strategy. The aim of this study was to explore the relevant genes and pathways of C...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46301

    authors: Peng Z,Su P,Yang Y,Yao X,Zhang Y,Jin F,Yang B

    更新日期:2020-09-09 00:00:00

  • Long noncoding RNA LINC01391 restrained gastric cancer aerobic glycolysis and tumorigenesis via targeting miR-12116/CMTM2 axis.

    abstract::Increasing studies indicate that long noncoding RNA (lncRNA) plays a critical role in aerobic glycolysis of various tumors. However, the contribution of lncRNA in gastric cancer (GC) cell glycolysis is still poorly understood. The objective of this research was to investigate the functional role and mechanism of lncRN...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.48365

    authors: Qian C,Xu Z,Chen L,Wang Y,Yao J

    更新日期:2020-08-27 00:00:00

  • Carbonic Anhydrase 4 serves as a Clinicopathological Biomarker for Outcomes and Immune Infiltration in Renal Cell Carcinoma, Lower Grade Glioma, Lung Adenocarcinoma and Uveal Melanoma.

    abstract::Background: Carbonic anhydrase 4 (CA4) maintains homeostasis of carbon dioxide and bicarbonate. It is suggested to be a potential prognostic biomarker, while the correlations between CA4 and different cancers are indistinct. Methods: Differential mRNA expression of CA4 among different cancers and corresponding normal ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46902

    authors: Xu Y,Xu WH,Shi SN,Yang XL,Ren YR,Zhuang XY,Qu YY,Zhang HL,Zhang XF

    更新日期:2020-08-25 00:00:00

  • Indications of neoadjuvant chemotherapy for locally advanced Gastric Cancer patients based on pre-treatment clinicalpathological and laboratory parameters.

    abstract::Objective: There are controversial indications for neoadjuvant chemotherapy (NAT) in the treatment of locally advanced gastric cancer (LAGC). Here, we aimed to identify indications for NAT based on pre-treatment clinicopathological and laboratory parameters. Methods: This study included a retrospective cohort of 1083 ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46430

    authors: Wang Y,Zhang J,Guo S,Meng XY,Zheng ZC,Zhao Y

    更新日期:2020-08-18 00:00:00

  • Risk factors and prognostic predictors for Cervical Cancer patients with lung metastasis.

    abstract::Background: The most common metastatic site in cervical cancers is lung. The aim of this study is to identify cervical cancer patients with high risk for developing lung metastasis and further explore their prognosis. Materials and Methods: At first, patients diagnosed with cervical cancer from 2010 to 2015 were ident...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46258

    authors: Chen X,Chen L,Zhu H,Tao J

    更新日期:2020-08-08 00:00:00

  • A novel seven-gene signature as Prognostic Biomarker in Hepatocellular Carcinoma.

    abstract:PURPOSE:Our study is designed to develop and certify a promising prognostic signature for hepatocellular carcinoma (HCC). Materials and methods: We retrospectively analyzed mRNA expression profiles and clinicopathological data fetched from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets. We fo...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.44573

    authors: Xie H,Liu S,Zhang Z,Chen P,Tao Y

    更新日期:2020-07-31 00:00:00

  • High serum Androgen and Insulin concentrations increase the tendency of Endometrial Carcinoma.

    abstract::Purpose: The objective of the study was to evaluate the important role played by androgen and insulin in the development of endometrial carcinoma (EC), and their combined effect on EC risk. Methods: We enrolled 510 type I EC patients and 510 age-, time-, and nationality-matched subjects into this study. Metabolic and ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46391

    authors: Teng F,Ma X,Yu X,Yan Y,Zhao J,Gao J,Gao C,Wang Y,Tian W,Xue F

    更新日期:2020-07-25 00:00:00

  • The development of bronchoscopy in China: a national cross-sectional study.

    abstract::Objective: To investigate the development of bronchoscopy in China and compare it with its application in the early 21st century. Methods: The data collection was based on questionnaires. Three hundred and nineteen hospitals, which distributed across 30 provinces and 130 cities, were included in the study. Data about ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.47183

    authors: Shi D,Li F,Wang K,Kong C,Huang H,Li Q,Jin F,Hu C,Wang C,Shi H,Hu Z,Dong Y,Ning Y,Tsakiridis K,Sapalidis K,Kosmidis C,Vagionas A,Hohenforst-Schmidt W,Freitag L,Turner JF,Drevelegas K,Perdikouri EI,Kovacevic T,

    更新日期:2020-07-20 00:00:00

  • A Predictive Nomogram for Early Death of Metastatic Gastric Cancer: A Retrospective Study in the SEER Database and China.

    abstract::Background: To identify associated risk factors and develop a predictive nomogram for the early death of metastatic gastric cancer patients. Methods: A total of 4575 patients in the SEER cohort and 220 patients in the Chinese cohort diagnosed with metastatic gastric cancer in our Cancer Center were obtained. Univariat...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46563

    authors: Zhu Y,Fang X,Wang L,Zhang T,Yu D

    更新日期:2020-07-14 00:00:00

  • Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer.

    abstract::Yes-associated protein (YAP) is a transcriptional coactivator that promotes cell proliferation, migration, and tissue homeostasis in colorectal cancer (CRC). Here, we established 5-Fu resistant CRC cell line (SW620R) and examined the role of YAP in chemotherapy resistance. We showed that YAP promoted cell proliferatio...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.44775

    authors: Huang C,Chen Z,Yang C,Chen L,Lai C,Zhang Y,Yuan W,Jeong JH

    更新日期:2020-07-11 00:00:00

  • IL10-modified Human Mesenchymal Stem Cells inhibit Pancreatic Cancer growth through Angiogenesis Inhibition.

    abstract::In the present study, we constructed the recombinant plasmid IL10-PEGFP-C1 and successfully transfected into human mesenchymal stem cells. After culturing for 72 h, the levels of IL6 and TNF-α in the supernatant of the MSCs-IL10 group were significantly lower than the vector group and the control group (17.6 ± 0.68vs7...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.38062

    authors: Zhao C,Pu Y,Zhang H,Hu X,Zhang R,He S,Zhao Q,Mu B

    更新日期:2020-07-09 00:00:00

  • Prognostic implication and functional annotations of APOBEC3G expression in patients with Melanoma.

    abstract::Aim: Skin cutaneous melanoma (SKCM) is one of the most life-threatening malignancies damaging human health. APOBEC3G (A3G) has been found in several cancers; however, the role of A3G in SKCM is rarely studied. This study aimed to investigate the expression of A3G in tumor tissue and its prognostic value in SKCM patien...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46383

    authors: Han W,Xu J,Shen GL

    更新日期:2020-07-06 00:00:00

  • YTHDF1 rs6090311 A>G polymorphism reduces Hepatoblastoma risk: Evidence from a seven-center case-control study.

    abstract::Various factors modulate the risk of hepatoblastoma. In this study, we aimed to investigate whether single nucleotide polymorphisms (SNPs) in the YTHDF1 gene could predispose to hepatoblastoma. We used TaqMan assay to genotype two YTHDF1 SNPs (rs6011668 C>T and rs6090311 A>G) in a Chinese population composed of 313 su...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.46120

    authors: Luo Z,Li G,Wang M,Zhu J,Yang Z,Li Y,Zhang J,Xin Y,Li S,Li L,Zhuo Z,He J

    更新日期:2020-06-28 00:00:00

  • Identification of Leukocyte telomere length-related genetic variants contributing to predisposition of Esophageal Squamous Cell Carcinoma.

    abstract::Background: Cancers may arise from cells with dysregulated telomeric functions due to shorten telomere length. We and others previously found that short leukocyte telomere length was associated with markedly evaluated risk of esophageal squamous cell carcinoma (ESCC). Hence, we hypothesized that single nucleotide poly...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.45165

    authors: Li Z,Song Y,Xu Y,Shen Y,Zhang N,Yang M,Yu D

    更新日期:2020-06-23 00:00:00

  • Downregulation of miR-1 in colorectal cancer promotes radioresistance and aggressive phenotypes.

    abstract::Background: Colorectal cancer (CRC) remains to be one of the most common malignancies worldwide. Various studies have demonstrated that microRNAs (miRs) play a critical role in regulating cancer progression and sensitivity to chemoradiotherapy. miR-1 was found to be aberrantly expressed in CRC. However, it has not bee...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.44753

    authors: Wu Y,Pu N,Su W,Yang X,Xing C

    更新日期:2020-06-07 00:00:00

  • Identification of LCA-binding Glycans as a Novel Biomarker for Esophageal Cancer Metastasis using a Lectin Array-based Strategy.

    abstract::Esophageal cancer (EC) is a unique and heterogeneous disease diagnosed mostly at advanced stages. Altered glycans presented on cell surfaces are involved in the occurrence and development of malignancy. However, the effects of glycans on EC progression are largely unexplored. Here, a lectin array was utilized to detec...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.43806

    authors: Xia M,Shao J,Qiao M,Luo Z,Deng X,Ke Q,Dong X,Shen L

    更新日期:2020-06-01 00:00:00

  • Novel Metabolomics Serum Biomarkers for Pancreatic Ductal Adenocarcinoma by the Comparison of Pre-, Postoperative and Normal Samples.

    abstract::Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The metabolomic approaches are developed to discover the novel biomarkers of PDAC. Methods: 550 preoperative, postoperative PDAC and normal controls (NCs) serums were employed to characterize metabolic alterations in ...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.41250

    authors: Zhang X,Shi X,Lu X,Li Y,Zhan C,Akhtar ML,Yang L,Bai Y,Zhao J,Wang Y,Yao Y,Li Y,Nie H

    更新日期:2020-05-19 00:00:00

  • LPS and IL-8 activated umbilical cord blood-derived neutrophils inhibit the progression of ovarian cancer.

    abstract::Background: Immunotherapy including immune checkpoint blockade, cancer vaccines, and adoptive cell therapy. However, no immune therapies support ovarian cancer. It is not clear whether the neutrophils, the component of the immune system derived from umbilical cord blood play a role in inhibiting the progression of ova...

    journal_title:Journal of Cancer

    pub_type: 杂志文章

    doi:10.7150/jca.41035

    authors: Liu Q,Yang W,Luo N,Liu J,Wu Y,Ding J,Li C,Cheng Z

    更新日期:2020-05-18 00:00:00

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