Activin A and follistatin influence expression of somatostatin in the ciliary ganglion in vivo.

abstract：:Although the development of several of the voltage-dependent currents in embryonic amphibian myocytes has been described, the overall muscle electrical development, particularly the relative times of expression of different voltage-dependent currents, has not been addressed in a single study under one set of condition...

journal_title：Developmental biology

authors： Spruce AE,Moody WJ

更新日期：1992-11-01 00:00:00

abstract：:In this paper we present a structural and functional characterization of a new sea urchin embryo transcription factor, SpRunt-1. This factor was isolated by means of its specific interaction with a cis-regulatory target site of the CyIIIa gene. Here we show that this target site, the P7I site, is required for normal e...

journal_title：Developmental biology

authors： Coffman JA,Kirchhamer CV,Harrington MG,Davidson EH

更新日期：1996-02-25 00:00:00

abstract：:Hoxa-11 and Hoxd-11 are paralogous genes required for proper development of the vertebral column, the limbs, and the urogenital system. To further explore the functional relationship between these genes, as well as the potential rescue of one function by the other, we have introduced a Hoxd-11-expressing transgene int...

journal_title：Developmental biology

authors： Zákány J,Gérard M,Favier B,Potter SS,Duboule D

更新日期：1996-06-15 00:00:00

abstract：:In the marine bivalve Hiatella flaccida, full-grown oocytes in ovaries are arrested at the first prophase (prophase-I) of meiosis, whereas spawned oocytes have reinitiated meiosis from prophase-I and are again arrested at the first metaphase (metaphase-I). The neurohormone serotonin (5-hydroxytryptamine, 5-HT) was abl...

journal_title：Developmental biology

authors： Deguchi R,Osanai K

更新日期：1995-10-01 00:00:00

abstract：:Thyroid hormone is a major regulator of postnatal brain development, but the precise molecular mechanisms underlying its action in this organ remain poorly understood. We used microarray analysis to identify new target genes in brain. Thyroid hormone treatment of hypothyroid Pax8(-/-) knockout mice, which lack thyroid...

journal_title：Developmental biology

authors： Poguet AL,Legrand C,Feng X,Yen PM,Meltzer P,Samarut J,Flamant F

更新日期：2003-02-15 00:00:00

abstract：:Choroideremia (CHM) is a hereditary eye disease caused by mutations in the X-linked CHM gene. Disruption of the Chm gene in mice resulted in prenatal death of Chm-/Y males and Chm-/Chm+ females that had inherited the mutation from their mothers. Male chimeras and Chm+/Chm- females with paternal transmission of the mut...

journal_title：Developmental biology

authors： Shi W,van den Hurk JA,Alamo-Bethencourt V,Mayer W,Winkens HJ,Ropers HH,Cremers FP,Fundele R

更新日期：2004-08-01 00:00:00

abstract：:Microtubule organization during the novel cell division of ameiotic microsporocytes was examined using indirect immunofluorescence microscopy. A recessive mutation of the maize gene Ameiotic causes the replacement of meiosis I with a synchronized mitotic division (Palmer, R. G. (1971). Chromosoma 35, 233-246). All ide...

journal_title：Developmental biology

authors： Staiger CJ,Cande WZ

更新日期：1992-11-01 00:00:00

abstract：:cAMP chemoattractant receptors on the surface of Dictyostelium discoideum cells are visualized by means of immunocytochemistry. Receptor antigen is virtually absent from growing cells and begins to accumulate after about 6 hr of starvation, concomitant with the increase in surface cAMP binding activity. In aggregating...

journal_title：Developmental biology

authors： Wang M,Van Haastert PJ,Devreotes PN,Schaap P

更新日期：1988-07-01 00:00:00

abstract：:Three dominant second-chromosome rearrangement mutations in Drosophila melanogaster, Aristapedioid1 (Arp), vestigial-Depilate (vgD), and vestigial62 (vg62), result in developmental abnormalities of the bristle sense organs on the notum, abdomen, legs, and wing margin. The bristle abnormalities are associated with over...

journal_title：Developmental biology

authors： Sharp EJ,Martin EC,Adler PN

更新日期：1994-02-01 00:00:00

abstract：:The remarkable regenerative capacity displayed by plants and various vertebrates, such as amphibians, is largely based on the capability of somatic cells to undergo dedifferentiation. In this process, mature cells reverse their state of differentiation and acquire pluripotentiality--a process preceding not only reentr...

journal_title：Developmental biology

authors： Grafi G

更新日期：2004-04-01 00:00:00

abstract：:The polypeptide sequence predicted from the Pem oncofetal gene cDNA contains a homeodomain most closely related to the paired class. Pem, paired class member orthodenticle, and the bicoid maternal gene product homeodomains all have lysine residues at a recognition helix position implicated in DNA-binding specificity. ...

journal_title：Developmental biology

authors： Rayle RE

更新日期：1991-07-01 00:00:00

abstract：:Cultured cells obtained from developing chick heart valvular and septal primordial tissues (cardiac cushions) and myocardium were tested for their capacity to bind, internalize, and degrade hyaluronate. A presumptive lysosomal hyaluronidase capable of hyaluronate degradation has been previously isolated and partially ...

journal_title：Developmental biology

authors： Bernanke DH,Orkin RW

更新日期：1984-12-01 00:00:00

abstract：:We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Polymorphism (SSLP) markers. Using a bioinformatics-based strategy, we identified unique SSLPs within the X. tropicalis genome. Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Simple Sequence Repeats (SSR...

journal_title：Developmental biology

authors： Wells DE,Gutierrez L,Xu Z,Krylov V,Macha J,Blankenburg KP,Hitchens M,Bellot LJ,Spivey M,Stemple DL,Kowis A,Ye Y,Pasternak S,Owen J,Tran T,Slavikova R,Tumova L,Tlapakova T,Seifertova E,Scherer SE,Sater AK

更新日期：2011-06-01 00:00:00

abstract：:Zygotes and embryos of the fucoid brown alga Pelvetia compressa undergo a series of asymmetric cleavages. We are interested in the developmental role of these cleavages and the mechanism controlling their alignment. To assess the importance of division plane alignment, the orientation of the first asymmetric division ...

journal_title：Developmental biology

authors： Bisgrove SR,Kropf DL

更新日期：1998-02-15 00:00:00

abstract：:Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as coordinated cell movements during looping and septation. DM-GRASP/ALCAM/CD166 is a member of the neuronal immunoglobulin domain superfamily of cell adhesion molecules and was recently suggested t...

journal_title：Developmental biology

authors： Gessert S,Maurus D,Brade T,Walther P,Pandur P,Kühl M

更新日期：2008-09-01 00:00:00

abstract：:Aurora-C was first identified during screening for kinases expressed in mouse sperm and eggs. Herein, we report for the first time the precise subcellular localization of endogenous Aurora-C during male meiotic division. The localization of Aurora-C was analyzed by immunofluorescence staining on chromosome spreads of ...

journal_title：Developmental biology

authors： Tang CJ,Lin CY,Tang TK

更新日期：2006-02-15 00:00:00

abstract：:Extracellular cAMP induces the intracellular synthesis and subsequent secretion of cAMP in Dictyostelium discoideum (relay). cAMP relay was strongly diminished in mutant HB3 which shows abnormal development by making very small fruiting bodies. Extracellular cAMP binds to receptors on the surface of mutant cells and i...

journal_title：Developmental biology

authors： Kesbeke F,Van Haastert PJ

更新日期：1988-12-01 00:00:00

abstract：:In embryos of Patella vulgata at the 32-cell stage, one of the four vegetally located macromeres makes contacts with overlying animal micromeres. As a result, this macromere (designated 3D) divides significantly later than the other macromeres and forms the mesodermal stem cell 4d. Shortly before and during this inter...

journal_title：Developmental biology

authors： Kühtreiber WM,van Dongen CA

更新日期：1989-04-01 00:00:00

abstract：:The murine homeobox genes Msx-1 and Msx-2 are related to the Drosophila msh gene and are expressed in a variety of tissues during mouse embryogenesis. We now report the developmentally regulated expression of Msx-1 and Msx-2 in the mouse mammary gland and show that their expression patterns point toward significant fu...

journal_title：Developmental biology

authors： Friedmann Y,Daniel CW

更新日期：1996-07-10 00:00:00

abstract：:One of the earliest steps in embryonic development is the establishment of the future body axes. Morphological and molecular data place the Ambulacraria (echinoderms and hemichordates) within the Deuterostomia and as the sister taxon to chordates. Extensive work over the last decades in echinoid (sea urchins) echinode...

journal_title：Developmental biology

authors： Röttinger E,Martindale MQ

更新日期：2011-06-01 00:00:00

abstract：:Previous study of the development of the levator ani muscle (LA) revealed that the sex difference in muscle fiber number is under the control of testosterone during the perinatal period. In this study, the development of the LA muscle was examined in both sexes to test the hypothesis that testosterone action determine...

journal_title：Developmental biology

authors： Joubert Y,Tobin C,Lebart MC

更新日期：1994-03-01 00:00:00

abstract：:NK-2-class homeobox genes have been identified in a variety of metazoans, from sponges to arthropods and vertebrates, and have been shown to play roles in a variety of cell and tissue specifications. Here we describe the characterization of the NK-2 homolog CnNK-2 from Hydra vulgaris, a freshwater cnidarian. CnNK-2 ex...

journal_title：Developmental biology

authors： Grens A,Gee L,Fisher DA,Bode HR

更新日期：1996-12-15 00:00:00

abstract：:The origin of the avian cardiovascular system from the primitive streak has been mapped by the construction of quail/chick transplantation chimeras, the use of QH-1 (an antiquail endothelial/endocardial cell marker), and injections of a vital fluorescent dye (DiI) into the primitive streak. Our studies reveal that the...

journal_title：Developmental biology

authors： Garcia-Martinez V,Schoenwolf GC

更新日期：1993-10-01 00:00:00

abstract：:Successful fertilization requires that sperm are activated prior to contacting an oocyte. In C. elegans, this activation process, called spermiogenesis, transforms round immobile spermatids into motile, fertilization-competent spermatozoa. We describe the phenotypic and genetic characterization of spe-43, a new compon...

journal_title：Developmental biology

authors： Krauchunas AR,Mendez E,Ni JZ,Druzhinina M,Mulia A,Parry J,Gu SG,Stanfield GM,Singson A

更新日期：2018-04-15 00:00:00

abstract：:In Hydra long-range interactions between head, bud, and foot formation take place in addition to short-range interactions which are recognized as induction phenomena, occurring when transplants are placed into an environment of disparate positional value. Here the long-range promotion of foot formation is analyzed. Th...

journal_title：Developmental biology

authors： Müller WA

更新日期：1995-01-01 00:00:00

abstract：:The term "transdifferentiation" has been used to describe the apparent phenotypic conversion of chick embryo neural retina Müller glial cells into lens-like cells in vitro. This phenotypic conversion is characterized by expression of such lens-specific proteins as delta crystallin and has been viewed as an example of ...

journal_title：Developmental biology

authors： Linser PJ,Irvin CK

更新日期：1987-06-01 00:00:00

abstract：:Neuronal circuit development and function require proper synapse formation and maintenance. Genetic screens are one powerful method to identify the mechanisms shaping synaptic development and stability. However, genes with essential roles in non-neural tissues may be missed in traditional loss-of-function screens. In ...

journal_title：Developmental biology

authors： Valakh V,Naylor SA,Berns DS,DiAntonio A

更新日期：2012-06-15 00:00:00

abstract：:The evolutionary divergence of cnidarian and bilaterian lineages from their remote metazoan ancestor occurred at an unknown depth in time before the Cambrian, since crown group representatives of each are found in Lower Cambrian fossil assemblages. We report here a variety of putative embryonic, larval, and adult micr...

journal_title：Developmental biology

authors： Chen JY,Oliveri P,Gao F,Dornbos SQ,Li CW,Bottjer DJ,Davidson EH

更新日期：2002-08-01 00:00:00

abstract：:Copyright ...

journal_title：Developmental biology

authors：

更新日期：1998-07-15 00:00:00

abstract：:Runx2-Cbfa1, a Runt transcription factor, plays important roles during skeletal development. It is required for differentiation and function of osteoblasts. In its absence, chondrocyte hypertrophy is severely impaired and there is no vascularization of cartilage templates during skeletal development. These tissue-spec...

journal_title：Developmental biology

authors： Wang W,Wang YG,Reginato AM,Glotzer DJ,Fukai N,Plotkina S,Karsenty G,Olsen BR

更新日期：2004-06-15 00:00:00