Abstract：
:Zygotes and embryos of the fucoid brown alga Pelvetia compressa undergo a series of asymmetric cleavages. We are interested in the developmental role of these cleavages and the mechanism controlling their alignment. To assess the importance of division plane alignment, the orientation of the first asymmetric division was altered and the effects on subsequent embryo elongation rates were analyzed. Although this division is normally oriented transversely (90 degrees) to the growth axis, deviations up to 45 degrees had no significant effects on embryo elongation. However, division planes that were parallel with the growth axis (0-45 degrees) had drastic effects. Embryo elongation was severely inhibited and the wall often bifurcated and avoided the rhizoid tip. The orientation of the division plane is determined by the position of the centrosomes. We therefore investigated centrosomal position and function during the first cell cycle within the three-dimensional context of the cell. We found that, after karyogamy, microtubule organization changed from a radially symmetric circumnuclear array into a bipolar centrosomal array. The reorganization coincided with the migration of the centrosomes around the nucleus. The centrosomes separated slowly and asynchronously until they reached opposite sides of the nuclear envelope. At this time the centrosomal axis, defined by the position of the two centrosomes, was oriented randomly with respect to the cortical growth axis. The centrosomal axis then rotated into alignment parallel with the growth axis late in the first cell cycle. These results indicate that the growth axis and the centrosomal axis develop independently of each other and that the centrosomal axis does not align with the growth axis until just prior to mitosis.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Bisgrove SR,Kropf DLdoi
10.1006/dbio.1997.8832subject
Has Abstractpub_date
1998-02-15 00:00:00pages
246-56issue
2eissn
0012-1606issn
1095-564Xpii
S0012-1606(97)98832-1journal_volume
194pub_type
杂志文章abstract：:Somatic embryogenesis is one of the best examples of the remarkable developmental plasticity of plants, in which committed somatic cells can dedifferentiate and acquire the ability to form an embryo and regenerate an entire plant. In Arabidopsis thaliana, the shoot apices of young seedlings have been reported as an al...
journal_title：Developmental biology
pub_type： 杂志文章
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abstract：:CHARGE syndrome is caused by spontaneous loss-of-function mutations to the ATP-dependant chromatin remodeller chromodomain-helicase-DNA-binding protein 7 (CHD7). It is characterised by a distinct pattern of congenital anomalies, including cardiovascular malformations. Disruption to the neural crest lineage has previou...
journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/s0012-1606(02)00080-5
更新日期：2003-03-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.0275
更新日期：1996-11-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
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journal_title：Developmental biology
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1998-06-01 00:00:00
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pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1987-08-01 00:00:00
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journal_title：Developmental biology
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1993.1123
更新日期：1993-05-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.0174
更新日期：1996-08-01 00:00:00
abstract：:Previous studies from this laboratory have identified a novel alpha-D-mannosidase on the sperm plasma membranes of several species, including man, which may have a role in fertilization. The polyclonal antibody raised against an isoform of the enzyme purified from rat epididymal fluid was found to cross-react with the...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.1050
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pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
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更新日期：2013-10-01 00:00:00
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journal_title：Developmental biology
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更新日期：2010-07-01 00:00:00
abstract：:beta-Catenin was originally identified biochemically as a protein that binds E-cadherin in cultured cells and that interaction was later shown to be essential for cadherin function. Independently, armadillo, the beta-catenin homolog in Drosophila melanogaster, was identified as a segment polarity gene necessary for th...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1997-12-15 00:00:00
abstract：:The dorsal air sacs supply oxygen to the flight muscles of the Drosophila adult. This tracheal organ grows from an epithelial tube (the air sac primordium (ASP)) that arises during the third larval instar (L3) from a wing-disc-associated tracheal branch. Since the ASP is generated by a program of both morphogenesis an...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2005.09.005
更新日期：2005-11-01 00:00:00
abstract：:Here we describe a novel set of peptidergic neurons conserved throughout all developmental stages in the Drosophila central nervous system (CNS). We show that a small complement of 28 apterous-expressing cells (Ap-let neurons) in the ventral nerve cord (VNC) of Drosophila larvae co-express numerous gene products. The ...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2004.01.015
更新日期：2004-05-01 00:00:00
