Competition for factors and cellular resources as a principle of pattern formation in Hydra. II. Assistance of foot formation by heads and buds and a new model of pattern control.

abstract：:The evolution of canalized traits is a central question in evolutionary biology. Natural variation in highly conserved traits can provide clues about their evolutionary potential. Here we investigate natural variation in a conserved trait-even-skipped (eve) expression at the cellular blastoderm stage of embryonic deve...

journal_title：Developmental biology

authors： Jiang P,Ludwig MZ,Kreitman M,Reinitz J

更新日期：2015-09-01 00:00:00

abstract：:In order to disclose the mechanism that regulate synapse development we compared the distributions of agrin, acetylcholine receptors (AChR) and a basal lamina heparan sulfate proteoglycan (HSPG) in sections and cultures prepared from Xenopus laevis and Ambystoma mexicanum embryos. While agrin, AChR and HSPG may accumu...

journal_title：Developmental biology

authors： Anderson MJ,Shi ZQ,Grawel R,Zackson SL

更新日期：1995-07-01 00:00:00

abstract：:During heart formation, the heart grows and undergoes dramatic morphogenesis to achieve efficient embryonic function. Both in fish and amniotes, much of the growth occurring after initial heart tube formation arises from second heart field (SHF)-derived progenitor cell addition to the arterial pole, allowing chamber f...

journal_title：Developmental biology

authors： Kula-Alwar D,Marber MS,Hughes SM,Hinits Y

更新日期：2021-02-01 00:00:00

abstract：:The uterus undergoes a series of dramatic changes in response to an implanting conceptus that, in some mammalian species, includes differentiation of the endometrial stroma into decidual tissue. This process, called decidualization, can be induced artificially in rodents indicating that the conceptus may not be essent...

journal_title：Developmental biology

authors： Bany BM,Cross JC

更新日期：2006-06-15 00:00:00

abstract：:This manuscript reports on the limb malformations and axial skeleton alterations found in legless fetuses and their heterozygote and wild-type littermates transplacentally exposed to all-trans-retinoic acid via a single intraperitoneal injection on Day 7, 8, 9, 9.5, 10, 10.5, or 11 of gestation. The most surprising as...

journal_title：Developmental biology

authors： Scott WJ,Collins MD,Ernst AN,Supp DM,Potter SS

更新日期：1994-07-01 00:00:00

abstract：:Actin dynamics are necessary at multiple steps in the formation of multinucleated muscle cells. BAR domain proteins can regulate actin dynamics in several cell types, but have been little studied in skeletal muscle. Here, we identify novel functions for the N-BAR domain protein, Bridging integrator 3 (Bin3), during my...

journal_title：Developmental biology

authors： Simionescu-Bankston A,Leoni G,Wang Y,Pham PP,Ramalingam A,DuHadaway JB,Faundez V,Nusrat A,Prendergast GC,Pavlath GK

更新日期：2013-10-01 00:00:00

abstract：:Although skeletal muscles appear superficially alike at different anatomical locations, in reality there is considerably more diversity than previously anticipated. Heterogeneity is not only restricted to completely developed fibers, but is clearly apparent during development at the molecular, cellular and anatomical ...

journal_title：Developmental biology

authors： Biressi S,Molinaro M,Cossu G

更新日期：2007-08-15 00:00:00

abstract：:The ubiquitin-proteasome system is essential for intracellular protein degradation, but there are few studies of this system in the extracellular milieu. Recently, we reported that a 70-kDa sperm receptor, HrVC70, on the vitelline coat is ubiquitinated and then degraded by the sperm proteasome during fertilization of ...

journal_title：Developmental biology

authors： Sakai N,Sawada H,Yokosawa H

更新日期：2003-12-01 00:00:00

abstract：:Metathoracic limb buds were removed unilaterally from Locusta migratoria embryos at 30% of embryonic development, thereby depriving limb-innervating neurons of the opportunity of innervating their normal target muscles. The operated embryos were allowed to hatch and develop to adulthood, and then the connections betwe...

journal_title：Developmental biology

authors： Whitington PM

更新日期：1985-02-01 00:00:00

abstract：:Melanoblasts, the precursors of the pigment-producing cells of the skin and hair, are derived from the neural crest and migrate to the skin around 12 days of gestation in the mouse. In adult mice almost all the melanoblasts are confined to the hair follicles except for the epidermal layers of nonhairy skin. The recept...

journal_title：Developmental biology

authors： Jordan SA,Jackson IJ

更新日期：2000-09-15 00:00:00

abstract：:Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are best known as regulators of the actin cytoskeleton, but in addition they control cell polarity, gene expression, microtubule dynamics and vesicular trafficking. Through these diverse func...

journal_title：Developmental biology

authors： Raftopoulou M,Hall A

更新日期：2004-01-01 00:00:00

abstract：:Cellular dedifferentiation underlies topical issues in biology such as regeneration and nuclear cloning and has common features in plants and animals. In plants, this process characterizes the transition of differentiated leaf cells to protoplasts (plant cells devoid of cell walls) and is accompanied by global chromat...

journal_title：Developmental biology

authors： Grafi G,Ben-Meir H,Avivi Y,Moshe M,Dahan Y,Zemach A

更新日期：2007-06-15 00:00:00

abstract：:Deficient nephrogenesis is the major factor contributing to renal hypoplasia defined as abnormally small kidneys. Nephron induction during kidney development is driven by reciprocal interactions between progenitor cells of the cap mesenchyme (CM) and the ureteric bud (UB). The prorenin receptor (PRR) is a receptor for...

journal_title：Developmental biology

authors： Song R,Preston G,Kidd L,Bushnell D,Sims-Lucas S,Bates CM,Yosypiv IV

更新日期：2016-01-15 00:00:00

abstract：:Hox genes encode transcription factors which provide positional information during morphogenesis along the body axis; genetic interaction among Hox genes is thought to be necessary for correct pattern formation. One of the most curious features of the 39 vertebrate Hox genes is that they form four clusters each compos...

journal_title：Developmental biology

authors： Suemori H,Noguchi S

更新日期：2000-04-15 00:00:00

abstract：:We describe the characterization and a functional analysis in Xenopus development of RalB, a small G protein. RalB RNA and protein are detectable during oogenesis and early development, but the gene is expressed only weakly in adult tissues. The RalB transcripts are processed by poly(A) extension during oocyte maturat...

journal_title：Developmental biology

authors： Moreau J,Lebreton S,Iouzalen N,Mechali M

更新日期：1999-05-15 00:00:00

abstract：:Defects in heart development are the most common congenital abnormalities in humans, providing a strong incentive to learn more about the underlying causes. Previous studies have implicated the metalloprotease-disintegrins ADAMs (a disintegrin and metalloprotease) 17 and 19 as well as heparin binding EGF-like growth f...

journal_title：Developmental biology

authors： Horiuchi K,Zhou HM,Kelly K,Manova K,Blobel CP

更新日期：2005-07-15 00:00:00

abstract：:Normal animal development requires accurate cell divisions, not only in the early stages of rapid embryonic cleavages, but also in later developmental stages. The Caenorhabditis elegans unc-85 gene is implicated only in cell divisions that occur post-embryonically, primarily in terminal neuronal lineages. Variable pos...

journal_title：Developmental biology

authors： Grigsby IF,Finger FP

更新日期：2008-07-01 00:00:00

abstract：:The ubiquitin ligase Smurf1 can target a handful of signaling proteins for ubiquitin-mediated proteasomal destruction or functional modification, including TGF-beta receptors, Smads, transcription factors, RhoA and MEKK2. Smurf1 was initially implicated in BMP pathway regulation in embryonic development, but its poten...

journal_title：Developmental biology

authors： Alexandrova EM,Thomsen GH

更新日期：2006-11-15 00:00:00

abstract：:The rabbit sperm membrane autoantigen RSA-1 is a sialoglycoprotein of 13,000 daltons which first appears on the surface of pachytene spermatocytes. Using specific antiserum to RSA-1 the antigen has been localized by immunofluorescence and immunoperoxidase staining. On testicular cells labeled at 37 degrees C, RSA-1 is...

journal_title：Developmental biology

authors： O'Rand MG,Romrell LJ

更新日期：1981-06-01 00:00:00

abstract：:Mutations that inactivate either merlin (mer) or expanded (ex) result in increased cell growth and proliferation in Drosophila. Both Mer and Ex are members of the Band 4.1 protein superfamily, and, based on analyses of mer ex double mutants, they are proposed to function together in at least a partially redundant mann...

journal_title：Developmental biology

authors： Pellock BJ,Buff E,White K,Hariharan IK

更新日期：2007-04-01 00:00:00

abstract：:We report periodic movements during erection of Dictyostelium discoideum (Dd) sorocarps. Our observations lead to the working hypothesis that Dd sorocarp erection occurs by two superimposed processes: one periodic, with a modal period of 6 1/2 min, and one continuous. We tentatively identify the periodic process with ...

journal_title：Developmental biology

authors： Durston AJ,Cohen MH,Drage DJ,Potel MJ,Robertson A,Wonio D

更新日期：1976-09-01 00:00:00

abstract：:The gastrointestinal (GI) tract of metazoans is lined by a series of regionally distinct epithelia. To maintain structure and function of the GI tract, regionally diversified differentiation of somatic stem cell (SC) lineages is critical. The adult Drosophila midgut provides an accessible model to study SC regulation ...

journal_title：Developmental biology

authors： Li H,Qi Y,Jasper H

更新日期：2016-11-15 00:00:00

abstract：:In vertebrates, hematopoietic and vascular progenitors develop from ventral mesoderm. The first primitive wave of hematopoiesis yields embryonic red blood cells, whereas progenitor cells of subsequent definitive waves form all hematopoietic cell lineages. In this report we examine the development of hematopoietic and ...

journal_title：Developmental biology

authors： Thompson MA,Ransom DG,Pratt SJ,MacLennan H,Kieran MW,Detrich HW 3rd,Vail B,Huber TL,Paw B,Brownlie AJ,Oates AC,Fritz A,Gates MA,Amores A,Bahary N,Talbot WS,Her H,Beier DR,Postlethwait JH,Zon LI

更新日期：1998-05-15 00:00:00

abstract：:The propagation of pluripotential mouse embryonic stem (ES) cells is sustained by leukemia inhibitory factor (LIF) or related cytokines that act through a common receptor complex comprising the LIF receptor subunit (LIF-R) and the signal transducer gp130. However, the findings that embryos lacking LIF-R or gp130 can d...

journal_title：Developmental biology

authors： Dani C,Chambers I,Johnstone S,Robertson M,Ebrahimi B,Saito M,Taga T,Li M,Burdon T,Nichols J,Smith A

更新日期：1998-11-01 00:00:00

abstract：:N-cadherin is a Ca2+-dependent cell-cell adhesion molecule, which was identified in brain cells of mouse and chicken. In the present study, we have determined the pattern of expression of N-cadherin in chicken embryos at various stages by means of immunohistochemistry. N-cadherin was expressed in cells derived from al...

journal_title：Developmental biology

authors： Hatta K,Takagi S,Fujisawa H,Takeichi M

更新日期：1987-03-01 00:00:00

abstract：:Previous study of the development of the levator ani muscle (LA) revealed that the sex difference in muscle fiber number is under the control of testosterone during the perinatal period. In this study, the development of the LA muscle was examined in both sexes to test the hypothesis that testosterone action determine...

journal_title：Developmental biology

authors： Joubert Y,Tobin C,Lebart MC

更新日期：1994-03-01 00:00:00

abstract：:The shoot meristem generates all of the aerial structures of an adult plant. It is organized in three layers which produce the epidermis (L1 layer) and the subepidermal layers (L2 and L3). The origin of adult structures has previously been fate mapped to the primary meristem for L2 and L3 tissues. In this work we cons...

journal_title：Developmental biology

authors： Schnittger A,Grini PE,Folkers U,Hülskamp M

更新日期：1996-05-01 00:00:00

abstract：:The molting cycle in insects is regulated by the fluctuating levels of ecdysteroids. Twenty-four hours prior to the pupal molt in Manduca sexta steroid titers are relatively high and they fall to very low levels at 4 hr before the molt. Several physiological events accompanying molts have been shown to require the ris...

journal_title：Developmental biology

authors： Mészáros M,Morton DB

更新日期：1994-04-01 00:00:00

abstract：:Organogenesis relies on specific genetic and molecular programmes, which orchestrate growth and cellular differentiation over developmental time. This is particularly important during Drosophila eye development in which cell-cell inductive events and long-range signalling have to be integrated to regulate proper cell ...

journal_title：Developmental biology

authors： Richard M,Hoch M

更新日期：2015-12-01 00:00:00

abstract：:This first study of the onset of spermatogenesis in the sea urchin, Strongylocentrotus purpuratus, was undertaken using individuals reared in the laboratory. Spermatogenesis commences about 11-12 months after metamorphosis in these animals. Bindin message accumulates in late spermatocytes and early spermatids which li...

journal_title：Developmental biology

authors： Cameron RA,Minor JE,Nishioka D,Britten RJ,Davidson EH

更新日期：1990-11-01 00:00:00