Gastric carcinoid with histamine production, histamine transporter and expression of somatostatin receptors.

abstract：:5 adrenalectomized subjects and 8 healthy volunteers underwent an insulin test during which acid secretion and plasma adrenaline, noradrenaline, dopamine and gastrin concentrations were measured. Plasma glucose concentration fell by greater than 50% in all subjects. The mean plasma adrenaline concentration increased m...

journal_title：Digestion

authors： Järhult J,Hamberger B,Lanthén G,Ors M,Uvnäs-Wallensten K

更新日期：1981-01-01 00:00:00

abstract：:Worldwide viral hepatitis is the most common cause of jaundice, chronic liver disease cirrhosis and hepatocellular carcinoma. While important advances have been made in prevention of viral hepatitis, therapy of this disease remains unsatisfactory. There are no specific therapies of proven benefit for acute hepatitis, ...

journal_title：Digestion

authors： Hoofnagle JH

更新日期：1998-08-01 00:00:00

abstract：:Germ-free and conventional rats were fed a semi-synthetic diet including 10% wheat bran for 1 month. They were compared to similar rats fed the same diet without bran. Transit of polyethylene glycol (PEG) 4000 was studied in giving the marker either in saline or in the diet. The presence of a bacterial flora was found...

journal_title：Digestion

authors： Riottot M,Sacquet E,Leprince C

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS:Several earlier studies on factors predicting the long-term outcome of ulcerative colitis only encompassed treatment failure for one severe episode, or suffered from a lack of multivariate analyses. We aimed to identify factors assessable at diagnosis or after the first induction therapy which predicted...

journal_title：Digestion

authors： Shiga H,Takagi S,Inoue R,Kinouchi Y,Ohkubo T,Takahashi S,Negoro K,Yokoyama H,Kato S,Fukushima K,Hiwatashi N,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Human colorectal neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. The biological behavior of NEC remains poorly understood. MATERIALS AND METHODS:We established two new NEC cell lines from a patient with rectal neuroendocrine carcinoma, NECS-P and NECS-L from the primary tumor an...

journal_title：Digestion

authors： Takahashi Y,Onda M,Tanaka N,Seya T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:In patients with active ulcerative colitis (UC), pharmacologics, although initially effective in most patients, are associated with refractoriness, loss of response or unfavourable side effects as additional morbidity factors. Depletion of myeloid lineage leucocytes like the CD14(+)CD16(+) monocyte phen...

journal_title：Digestion

authors： Iida T,Ikeya K,Kato M,Abe J,Yamamoto M,Watanabe F,Sugimoto K,Hanai H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIM:Studies have demonstrated an important role for endogenous PG and NO in the healing of chronic gastric ulcers. We investigated the effects of COX and NOS inhibitors on the healing of duodenal ulcers, in comparison with gastric ulcers, in rats. METHODS:Gastric and duodenal ulcers were induced by serosal ...

journal_title：Digestion

authors： Araki H,Komoike Y,Matsumoto M,Tanaka A,Takeuchi K

更新日期：2002-01-01 00:00:00

abstract：:Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagn...

journal_title：Digestion

authors： Okubo M,Tahara T,Shibata T,Nakamura M,Kamiya Y,Yoshioka D,Maeda Y,Yonemura J,Ishizuka T,Arisawa T,Hirata I

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The frequency of benign stenosis in ulcerative colitis (UC) is low, reported as being 3.2-11.2%, with fibrosis in the submucosa or deeper pointed out as one of the causes. The aim of the present study was to assess stenosis in UC cases using immunostaining and to analyze differences between stenotic...

journal_title：Digestion

authors： Yamagata M,Mikami T,Tsuruta T,Yokoyama K,Sada M,Kobayashi K,Katsumata T,Koizumi W,Saigenji K,Okayasu I

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:The incidence of early-onset inflammatory bowel disease is increasing in Japan. OBJECTIVE:This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease. METHODS:This prospective survey evaluated the data of 43 patients aged <8 years who were diagnosed with inflammatory ...

journal_title：Digestion

authors： Kudo T,Fujii T,Maisawa SI,Sasaki M,Uchida K,Ida S,Kagimoto S,Yoden A,Shimizu T

更新日期：2020-05-18 00:00:00

abstract：:Activation of enzyme phospholipase A2 (EC 3.1.1.4), the major liberator of arachidonic acid, has been proposed as a component in the pathogenesis of inflammatory bowel disease. To test the hypothesis that phospholipase A2 activity is increased in ulcerative colitis, enzyme activity was investigated in colonic biopsies...

journal_title：Digestion

authors： Almer S,Franzén L,Olaison G,Smedh K,Ström M

更新日期：1991-01-01 00:00:00

abstract：:Leucine absorption across the mechanically obstructed rat intestine was studied by in vivo and in vitro techniques. It varied between the early (after 2 h) and late (after 18 h) phases of the obstruction. During the early phase there was a reduction in mucosal uptake and in net absorption of the amino acid. At 18 h th...

journal_title：Digestion

authors： Hajjar JJ,Schwartz RG,Mirkin KR,Tomicic TK

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND AIM:Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients...

journal_title：Digestion

authors： Ciccone A,Gabrieli D,Cardinale R,Di Ruscio M,Vernia F,Stefanelli G,Necozione S,Melideo D,Viscido A,Frieri G,Latella G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Pentoxifylline has many anti-inflammatory properties including inhibition of production of tumor necrosis factor alpha (TNF-alpha). Although pentoxifylline prevents several types of gastric mucosal injury, the effect of this drug on ulcer healing is unknown. In this study, we examined the effect of pent...

journal_title：Digestion

authors： Shimizu N,Watanabe T,Arakawa T,Fujiwara Y,Higuchi K,Kuroki T

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study was to examine the relative importance of the enzymes ornithine decarboxylase (ODC) and diamine oxidase (DAO) in intestinal polyamine metabolism in normal rats. To study this we measured jejunal and ileal DAO and ODC activities and polyamine levels 2 h after injecting, in non-fasting male Wistar ...

journal_title：Digestion

authors： Rokkas T,Vaja S,Taylor P,Murphy GM,Dowling RH

更新日期：1990-01-01 00:00:00

abstract：:Biliopancreatic bypass (BPB), a bariatric surgical procedure, leads to a malnutrition-induced general visceral atrophy except for the pancreas. This work investigates the implication of cholecystokinin (CCK) in the exocrine pancreatic adaptive process using a plasma CCK assay and the CCK receptor antagonist CR 1409. N...

journal_title：Digestion

authors： Evrard S,Hoeltzel A,Aprahamian M,Bernard C,Mutter D,Marescaux J,Damgé C

更新日期：1994-01-01 00:00:00

abstract：:The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinom...

journal_title：Digestion

authors： Lehmann FG,Kornacher J

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Double-filtration plasmapheresis (DFPP) together with interferon (IFN) administration produces a substantial reduction in the viral load during the early stages of treatment. METHODS:Based on their responses to previous pegylated IFN and ribavirin (PEG-IFN/RBV) therapy, 20 patients were divided int...

journal_title：Digestion

authors： Kim SR,Saito J,Imoto S,Komaki T,Nagata Y,Kim KI,Sasase N,Kimura N,Sasatani K,Konishi E,Hasegawa Y,Fujinami A,Ohta M,El-Shamy A,Tanaka Y,Sugano M,Sakashita M,Nakamura A,Tsuchida S,Makino T,Kawada T,Nakajima T,M

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Weakly acidic reflux has been reported to be the major cause of symptoms in patients with proton pump inhibitor (PPI)-refractory nonerosive reflux disease (NERD) undergoing PPI treatment. We previously reported that reflux at pH 4-5 was the main factor that induced symptoms in such patients. The present st...

journal_title：Digestion

authors： Abe Y,Koike T,Saito M,Okata T,Nakagawa K,Hatta W,Asanuma K,Uno K,Asano N,Imatani A,Masamune A

更新日期：2020-02-14 00:00:00

abstract：BACKGROUND/AIMS:In this study, a clinical and serological follow-up of 8-10 years was performed in relatives of celiac disease (CD) patients from southern Brazil. The occurrence of new CD cases in the families and the use of two different IgA-tTG enzyme-linked immunosorbent assay (ELISA) kits were also evaluated. METH...

journal_title：Digestion

authors： Nass FR,Kotze LM,Nisihara RM,de Messias-Reason IJ,Ramos da Rosa Utiyama S

更新日期：2011-01-01 00:00:00

abstract：:Whether and to what extent the pancreas is involved in acute viral hepatitis is still unclear. In order to address this issue we evaluated serum and urinary amylase and isoamylase levels in 92 patients with acute viral hepatitis of different etiology and in 60 healthy volunteers. Furthermore, pancreatic structure and ...

journal_title：Digestion

authors： Taranto D,Carrato A,Romano M,Maio G,Izzo CM,Del Vecchio Blanco C

更新日期：1989-01-01 00:00:00

abstract：:The effect of feeding an alpha-amylase inhibitor (BAY e 4609, 700 mg/100 g food) for 20 or 90 days on the enzymes of the exocrine pancreas of the rat was investigated. The amylase inhibitor-fed rats gained significantly less weight despite a higher food intake than control rats on a standard diet. Fecal weight increas...

journal_title：Digestion

authors： Fölsch UR,Grieb N,Caspary WF,Creutzfeldt W

更新日期：1981-01-01 00:00:00

abstract：:Electrophoretic studies of inactive ductal pancreatic secretions, collected on five successive days following operation, demonstrated up to 18 protein bands. Comparison of the densitometric scans on the first and fourth days was as follows: the patterns from different individuals appeared similar during the periods of...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) infection exacerbates ulcerative colitis (UC) refractory to immunosuppressive therapies (IMT). However, the underlying UC remained active in some UC patients, despite the fact that CMV-DNA in colonic mucosa became negative after antiviral therapy. Therefore, new therapeutic strategies f...

journal_title：Digestion

authors： Yoshino T,Nakase H,Matsuura M,Matsumura K,Honzawa Y,Fukuchi T,Watanabe K,Murano M,Tsujikawa T,Fukunaga K,Matsumoto T,Chiba T

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

journal_title：Digestion

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-11-18 00:00:00

abstract：:We report on a 39-year-old woman suffering from deep venous thrombosis due to a heterozygous factor-V-Leiden mutation with resistance to activated protein C. Four months after beginning oral anticoagulation, generalized jaundice appeared. Subsequently, subacute liver failure developed necessitating an orthotopic liver...

journal_title：Digestion

authors： Mix H,Wagner S,Böker K,Gloger S,Oldhafer KJ,Behrend M,Flemming P,Manns MP

更新日期：1999-11-01 00:00:00

abstract：:The effects of somatostatin on cholera toxin-induced secretory diarrhea and the appearance of glycoenzymes in the intestinal lumen and intestinal lymph were investigated in rat small intestine. After exposure to cholera toxin, marked fluid accumulation in the small intestinal tract and elevation of the jejunal mucosal...

journal_title：Digestion

authors： Yoshioka M,Asakura H,Hamada Y,Miura S,Kobayashi K,Morishita T,Morita A,Tsuchiya M

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Overt hepatic encephalopathy (HE) following insertion of a transjugular intrahepatic portosystemic shunt (TIPS) is a problem in some patients. In contrast to overt HE, minimal HE (MHE) following TIPS is studied to a limited degree only. We therefore evaluated the incidence of MHE in patients following TIPS i...

journal_title：Digestion

authors： Biecker E,Hausdörfer I,Grünhage F,Strunk H,Sauerbruch T

更新日期：2011-01-01 00:00:00

abstract：:Fragments of benign colonic adenomatous polyps of man, adenocarcinoma of the colon of man, and normal colonic mucosa of man and rodent were transplanted under the kidney capsule of athymic mice. Benign human adenomatous cells survived for periods of up to 28 days, normal rodent colonic epithelial cells for 45 days and...

journal_title：Digestion

authors： Bhargava DK,Lipkin M

更新日期：1981-01-01 00:00:00

abstract：:The core symposiums of the Japanese Gastroenterological Association (JGA) annual scientific meetings focus on similar topics from year to year. The main topics of these symposiums for the last 3 years were centered on progress in new diagnostics and therapeutic strategies for gastrointestinal malignancy, with a specia...

journal_title：Digestion

authors： Sugiyama T

更新日期：2015-01-01 00:00:00