The Ameliorating Effect of Switching to Vonoprazan: A Novel Potassium-Competitive Acid Blocker in Patients with Proton Pump Inhibitor Refractory Non-Erosive Reflux Disease.

abstract：BACKGROUND:Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy in laparoscopic surgery is radical, similar to that of open gastrectomy for patients with early gastric ca...

journal_title：Digestion

authors： Hiramatsu Y,Takeuchi H,Goto O,Kikuchi H,Kitagawa Y

更新日期：2019-01-01 00:00:00

abstract：:Compared with other imaging modalities and clinical investigation, the 111In-pentetreotide scan identified additional metastatic disease sites in 12 carcinoid patients and 2 occult primaries, and influenced the therapeutic outcome in 36 patients [29 carcinoids, 2 atypical carcinoids, 3 cancers of unknown primaries (CU...

journal_title：Digestion

authors： Anthony LB,Martin W,Delbeke D,Sandler M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Currently, a split-dose of polyethylene glycol (PEG) is the mainstay of bowel preparation due to its tolerability, bowel-cleansing action, and safety. However, bowel preparation with PEG is suboptimal because residual fluid reduces the polyp detection rate and requires a more thorough colon inspection. ...

journal_title：Digestion

authors： Kim HJ,Kim TO,Shin BC,Woo JG,Seo EH,Joo HR,Heo NY,Park J,Park SH,Yang SY,Moon YS,Shin JY,Lee NY

更新日期：2012-01-01 00:00:00

abstract：:Previous investigations have demonstrated that the cellular signaling induced by hypoxia-reoxygenation is a major pathway contributing to gastric mucosal injury induced by stress, non-steroidal anti-inflammatory drugs, and Helicobacter pylori. The aim of the present study was to perform a gene expression analysis of t...

journal_title：Digestion

authors： Katada K,Naito Y,Mizushima K,Takagi T,Handa O,Kokura S,Ichikawa H,Yoshida N,Matsui H,Yoshikawa T

更新日期：2006-01-01 00:00:00

abstract：:The basal (interdigestive) gastrointestinal motor activity and the interdigestive gastric acid and pancreatic amylase secretion were determined in 10 young smokers (mean age 23 years) and 7 nonsmokers (mean age 26 years). There was no significant difference in the length of the interdigestive motor complex between smo...

journal_title：Digestion

authors： Demol P,Singer MV,Hotz J,Dipp M,Goebell H

更新日期：1984-01-01 00:00:00

abstract：:Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...

journal_title：Digestion

authors： Panda AP,Laughton JM,Elder JB,Gillespie IE

更新日期：1975-01-01 00:00:00

abstract：:We consider the multiple interacting factors which lead to the proliferation of human gastric enterochromaffin-like (ECL) cells, and control of this proliferation by somatostatin and its analogues. Somatostatin receptors occur in human fundic mucosa, and octreotide can be considered a useful therapeutic tool to contro...

journal_title：Digestion

authors： Delle Fave G,Annibale B

更新日期：1996-01-01 00:00:00

abstract：:Gastric actions of Nw-nitro-1-arginine methyl ester (L-NAME) were investigated in rats, as this agent is a reliable nitric oxide synthase inhibitor L-NAME solutions were placed in subcutaneous osmotic minipumps which continuously released L-NAME at 0.1, 1.0, 10, or 40 mg/kg/day. L-NAME dose and time-dependently enhanc...

journal_title：Digestion

authors： Qiu BS,Pfeiffer CJ,Cho CH

更新日期：1996-01-01 00:00:00

abstract：:Fructus has motivation effect on gastrointestinal tract. Hesperidin is extracts of Fructus, and we attempted to prove its effects on improving the gastrointestinal transmission function and determine the possible mechanisms by a loperamide-induced slow transit constipation (STC) model. Constipation phenotypes were mea...

journal_title：Digestion

authors： Wu M,Li Y,Gu Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Different food items are made responsible for irritable bowel syndrome (IBS) symptoms, but the physiopathology of IBS remains unclear. AIMS:During a meeting in Nice, France, experts of the European Working Team of the IBiS Club discussed selected data regarding the relationships between alimentation, food i...

journal_title：Digestion

authors： Dapoigny M,Stockbrügger RW,Azpiroz F,Collins S,Coremans G,Müller-Lissner S,Oberndorff A,Pace F,Smout A,Vatn M,Whorwell P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIM:Several studies performed in Western countries demonstrate the association between sleep dysfunction and gastroesophageal reflux disease (GERD), especially when nighttime heartburn is present. The purpose of this study was to examine the prevalence and risk factors of sleep dysfunction, and the effec...

journal_title：Digestion

authors： Fujiwara Y,Kohata Y,Kaji M,Nebiki H,Yamasaki T,Sasaki E,Hayakawa T,Machida H,Tanigawa T,Watanabe K,Watanabe T,Tominaga K,Arakawa T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Medical therapy of inflammatory bowel disease (IBD) is becoming more complex, given the increasing choice of drugs to treat Crohn's disease (CD) and ulcerative colitis (UC). We aimed to summarize the current guidelines for first-line treatments in IBD. METHODS:An extensive literature search with fo...

journal_title：Digestion

authors： Girardin M,Manz M,Manser C,Biedermann L,Wanner R,Frei P,Safroneeva E,Mottet C,Rogler G,Schoepfer AM

更新日期：2012-01-01 00:00:00

abstract：:Electroencephalographic tracings of 50 patients with ulcerative colitis (UC) were compared with those of 75 controls. In the UC patients a 24% incidence of abnormal tracings was found as compared with an 8% incidence in the controls. A higher incidence of abnormal electroencephalograms was found among active cases of ...

journal_title：Digestion

authors： Eschar J,Arlazoroff A,Kleinhaus M,Mera A,Gilat T,Weissman I

更新日期：1975-01-01 00:00:00

abstract：:The effect of human leukocyte interferon (IFN) on natural killer (NK) activity in 7 patients with HBsAg-positive chronic active hepatitis was investigated. Human leukocyte IFN was intramuscularly given once a week for 4 consecutive weeks (10 X 10(5), 5 X 10(5), 2 X 10(5) and 1 X 10(5) U). 1 week after the initial inje...

journal_title：Digestion

authors： Matsumura N,Yoshikawa T,Kondo M,Imanishi J,Kishida T

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Intravenous iron and erythropoietin have been shown to be effective in Crohn's disease-associated anemia. The aim of this study was to test the sequential treatment of anemia in ulcerative colitis with intravenous iron in the first phase and erythropoietin in the second. PATIENTS AND METHODS:Twenty patients...

journal_title：Digestion

authors： Gasche C,Dejaco C,Reinisch W,Tillinger W,Waldhoer T,Fueger GF,Lochs H,Gangl A

更新日期：1999-01-01 00:00:00

abstract：:Lithium is a cation which has central nervous system effects and is able to interfere with both the release and action of polypeptide hormones. We examined its effect on basal and stimulated plasma gastrin and pancreatic polypeptide (PP) levels in 4 dogs with chronic gastric fistulas. Gastrin and PP release were stimu...

journal_title：Digestion

authors： Modlin IM,Ehrlich BE,Lamers CB,Diamond JM,Walsh JH

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND AIM:Along with the widespread use of eradication for Helicobacter pylori (H. pylori), the incidence of gastric cancer after eradication has also been increasing. There is a need for clarification of the clinical and biological characteristics of these neoplasms. PATIENTS AND METHODS:We studied 27 cases ...

journal_title：Digestion

authors： Matsuo T,Ito M,Tatsugami M,Boda T,Takata S,Tanaka S,Chayama K

更新日期：2012-01-01 00:00:00

abstract：:We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

journal_title：Digestion

authors： Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

更新日期：1994-01-01 00:00:00

abstract：:Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

journal_title：Digestion

authors： Okabe S,Tabata K

更新日期：1981-01-01 00:00:00

abstract：INTRODUCTION:Impaired intestinal epithelial barrier function is a hallmark of a variety of pathological conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). IBD patients with IBS-like symptoms show higher interleukin-13 (IL-13) serum levels and poor psychological well-being. Supplemen...

journal_title：Digestion

authors： Li M,Oshima T,Ito C,Yamada M,Tomita T,Fukui H,Miwa H

更新日期：2019-09-18 00:00:00

abstract：INTRODUCTION:Colonic diverticulosis is a common condition with obscure pathogenesis. Obesity, hyperlipidemia and hypertension have been demonstrated to increase the risk of complicated diverticular disease, but the impact of metabolic risk factors on the prevalence of uncomplicated diverticulosis has not been clearly d...

journal_title：Digestion

authors： Kopylov U,Ben-Horin S,Lahat A,Segev S,Avidan B,Carter D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Leptin, a product of the ob gene controlling food intake, has recently been detected in the stomach and shown to be released by cholecystokinin (CCK) and to induce gastroprotection against various noxious agents, but it is not known whether centrally applied leptin influences gastric secretion and mucosal in...

journal_title：Digestion

authors： Brzozowski T,Konturek PC,Konturek SJ,Pierzchalski P,Bielanski W,Pajdo R,Drozdowicz D,Kwiecień S,Hahn EG

更新日期：2000-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS:The changes in gastroesophageal reflux disease (GERD)-related symptoms on treatment are variously described, but currently available questionnaires have shortcomings. We therefore developed a self-assessment reflux questionnaire (ReQuest). This article describes the process of development and testing. ...

journal_title：Digestion

authors： Bardhan KD,Stanghellini V,Armstrong D,Berghöfer P,Gatz G,Mönnikes H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:In this report, we aimed to investigate the distribution and characterization of biomarker-immunolabeled ductal epithelium in advanced pancreatic ductal adenocarcinoma (PDAC). DESIGN:Eighteen patients with PDAC were medically diagnosed prior to being treated periodically. All clinical records were coll...

journal_title：Digestion

authors： Zhou R,Xu X,Liu M,Wu X,Li R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The safety of carbon dioxide (CO(2)) insufflation has not been fully established for esophageal and gastric endoscopic submucosal dissection (ESD) under deep sedation, because CO(2) retention is not only caused by CO(2) insufflation but also by the sedation level and the patient's respiratory status...

journal_title：Digestion

authors： Takano A,Kobayashi M,Takeuchi M,Hashimoto S,Mizuno K,Narisawa R,Aoyagi Y

更新日期：2011-01-01 00:00:00

abstract：:Hepatitis B surface antigen (HBsAg)-associated receptors for polymerized human serum albumin (RpHSA) are assumed to mediate viral attachment to hepatocytes in hepatitis B virus (HBV) infection. RpHSA was found to be coded by the pre-S region of HBV genome. Recently, the antiviral effect of recombinant leukocyte alpha-...

journal_title：Digestion

authors： Gerken G,Manns M,Hess G,Meyer zum Büschenfelde KH

更新日期：1987-01-01 00:00:00

abstract：:The healing of acetic acid-induced gastric and duodenal ulcers was examined together with the biochemical indices of growth in gastric and duodenal mucosa in the following three groups of rats: (a) chow-fed, (b) fed an isocaloric liquid diet, (c) fed the liquid diet plus pentagastrin injections (250 micrograms/kg, 3 t...

journal_title：Digestion

authors： Takeuchi K,Johnson LR

更新日期：1986-01-01 00:00:00

abstract：:The adaptive increase in bile flow was studied up to 24 h after selective biliary obstruction (SBO) in the rat. Between 6 and 12 h after SBO bile flow increased significantly, such that 12 and 24 h after SBO bile flow did not differ significantly from control. The prior administration of cycloheximide (300 micrograms/...

journal_title：Digestion

authors： Mackinnon M,Kohler M

更新日期：1980-01-01 00:00:00

abstract：:Intestinal absorption after extensive small bowel resections, for diseases other than Crohn's disease, was studied in 17 patients. When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections...

journal_title：Digestion

authors： Cosnes J,Gendre JP,Le Quintrec Y

更新日期：1978-01-01 00:00:00