Gene expression profiles on hypoxia and reoxygenation in rat gastric epithelial cells: a high-density DNA microarray analysis.

abstract：:The distribution of tryptophan hydroxylase, the rate-limiting enzyme in the biosynthesis of serotonin, was investigated immunohistochemically in various organs of the gastrointestinal tract and compared with that of neuroendocrine markers. While immunoreactivity for serotonin and chromogranin A was restricted to enter...

journal_title：Digestion

authors： Meyer T,Brinck U

更新日期：1999-01-01 00:00:00

abstract：:The influence of CDCA and UDCA administration on human intestinal permeability to lactulose, as disclosed by intravenous CCK, has been investigated. For this purpose the fraction of lactulose excreted in the urine during 5 h after an oral load of the disaccharide in hypertonic solution was measured in 12 healthy subje...

journal_title：Digestion

authors： Budillon G,Parrilli G,Capuano G,Mazzacca G,Menzies IS

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate the frequency of anatomic variations of the hepatic duct bifurcation using magnetic resonance cholangiopancreatography (MRCP). METHODS:A total of 1,160 consecutive patients, referred to our department for MRCP due to suspected pancreatobiliary disease or before liver tra...

journal_title：Digestion

authors： Uysal F,Obuz F,Uçar A,Seçil M,Igci E,Dicle O

更新日期：2014-01-01 00:00:00

abstract：:Omeprazole was administered for up to 6 years in 859 patients for 'prevention of relapse in patients with poorly responsive peptic ulcer or reflux oesophagitis'. The pattern of adverse events reported during long-term treatment was similar to the adverse-event profile in short-term treatment with omeprazole (n = 2,818...

journal_title：Digestion

authors： Joelson S,Joelson IB,Lundborg P,Walan A,Wallander MA

更新日期：1992-01-01 00:00:00

abstract：:Functional changes of the exocrine pancreas in cerulein-induced pancreatitis were evaluated with the isolated perfused rat pancreas. In control specimens (n = 7), baseline pancreatic juice volume was 0.23 +/- 0.06 microliter/min and after stimulation with CCK-8 (10(-10) M) and secretin (10(-10) M), it was 2.26 +/- 0.4...

journal_title：Digestion

authors： Ando K,Manabe T,Kyogoku T,Ohshio G,Yotsumoto F,Tamura K,Imanishi K,Yositomi S,Tobe T

更新日期：1992-01-01 00:00:00

abstract：:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/o...

journal_title：Digestion

authors： Nakamura T,Nagahori M,Kanai T,Watanabe M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Some minimal changes (MCs) are believed to have a certain relationship with gastroesophageal reflux (GERD). Nonetheless, the individual meaning of MC is still unclear. Our aim was to compare the overall and individual prevalence of MC between patients with non-erosive reflux disease (NERD) and healthy c...

journal_title：Digestion

authors： Kim JB,Shin SR,Shin WG,Choi MH,Jang HJ,Kim KO,Park CH,Baek IH,Baik GH,Kim KH,Park SH,Kae SH,Lee MS,Kim HY

更新日期：2012-01-01 00:00:00

abstract：:Rats were subjected to serial venesections 3 days prior to and then sequentially for 4 weeks after surgical removal of either the proximal or distal half of the small bowel. Total serum protein concentration and protein electrophoretic patterns were determined on these sera. Both sham-operated and unoperated animals s...

journal_title：Digestion

authors： Urban E,Ricks PM

更新日期：1980-01-01 00:00:00

abstract：:6 patients with Crohn's disease for 1-14 years have been treated with plasmapheresis for periods of up to 6 months. The symptoms of the one newly diagnosed patient were controlled by plasmapheresis alone, and 5 steroid-dependent patients were able to reduce their steroid requirements. During the study period, 13 clini...

journal_title：Digestion

authors： Holdstock GE,Fisher JA,Hamblin TJ,Loehry C

更新日期：1979-01-01 00:00:00

abstract：:The uptake of prostaglandin E1 by rat intestine mucosal strips was investigated. The results indicate that: (1) PGE1 did not accumulate in the epithelial cells of rat intestine. The intracellular to extracellular distribution ratio did not reach unity in spite of the extended periods of incubation. (2) A decrease in t...

journal_title：Digestion

authors： Nassar CF,Haddad ME,Khuri RN

更新日期：1982-01-01 00:00:00

abstract：:OctreoTher ((90)Y-DOTA-D-Phe(1)-Tyr(3)-octreotide, a.k.a. (90)Y-SMT 487) consists of a somatostatin peptide analogue (Tyr(3)-octreotide), coupled with a complexing moiety (DOTA), and labeled with a tightly bound beta-emitter (yttrium-90). By targeting somatostatin receptor-positive tumors (as imaged by OctreaScan it m...

journal_title：Digestion

authors： Smith MC,Liu J,Chen T,Schran H,Yeh CM,Jamar F,Valkema R,Bakker W,Kvols L,Krenning E,Pauwels S

更新日期：2000-01-01 00:00:00

abstract：:Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...

journal_title：Digestion

authors： Panda AP,Laughton JM,Elder JB,Gillespie IE

更新日期：1975-01-01 00:00:00

abstract：:83 patients with chronic active hepatitis (CAH), 38 of them with cirrhosis, were studied and compared with 10 control subjects suffering from chronic persistent hepatitis (CPH). Tubular acidosis frequently was found in our cases. Renal plasma flow and glomerular filtration rate were significantly decreased in CAH when...

journal_title：Digestion

authors： Gentilini P,Laffi G,Buzzelli G,Stefani P,Scarpelli P,Paladini S,Smorlesi C,La Villa G,Forti G

更新日期：1980-01-01 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：:There are many controversies concerning the treatment of hemorrhages of the upper gastrointestinal tract. In order to determine whether some currently used drugs, such as somatostatin (SST) and ranitidine, may be useful in the control of hemorrhages, we have conducted a controlled (not blind) study with alternate assi...

journal_title：Digestion

authors： Coraggio F,Bertini G,Catalano A,Scarpato P,Gualdieri L

更新日期：1989-01-01 00:00:00

abstract：:Lithium is a cation which has central nervous system effects and is able to interfere with both the release and action of polypeptide hormones. We examined its effect on basal and stimulated plasma gastrin and pancreatic polypeptide (PP) levels in 4 dogs with chronic gastric fistulas. Gastrin and PP release were stimu...

journal_title：Digestion

authors： Modlin IM,Ehrlich BE,Lamers CB,Diamond JM,Walsh JH

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Human colorectal neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. The biological behavior of NEC remains poorly understood. MATERIALS AND METHODS:We established two new NEC cell lines from a patient with rectal neuroendocrine carcinoma, NECS-P and NECS-L from the primary tumor an...

journal_title：Digestion

authors： Takahashi Y,Onda M,Tanaka N,Seya T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Westernization, above all associated changes in diet, has been postulated to be one of the most important factors contributing to the increasing incidence in inflammatory bowel disease (IBD), consisting mainly of Crohn's disease and ulcerative colitis. SUMMARY:Diet represents a crucially important and intui...

journal_title：Digestion

authors： Schreiner P,Martinho-Grueber M,Studerus D,Vavricka SR,Tilg H,Biedermann L,on behalf of Swiss IBDnet, an official working group of the Swiss Society of Gastroenterology.

更新日期：2020-01-01 00:00:00

abstract：:Daily faecal calcium and magnesium outputs were inversely related to food-stimulated colonic intraluminal pressure in diverticular disease subjects. There was no relationship to sodium potassium and bile acid concentrations, nor to intestinal transit. ...

journal_title：Digestion

authors： Eastwood MA,Smith AN,Mitchell WD,Pritchard JL

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND/AIMS:While probiotic bacteria are successfully used in the treatment of ulcerative colitis, the effect of commercially available probiotic products is still controversial. Here, we study whether the number of living probiotic bacteria in yoghurts is altered by an interruption of the cold chain. METHODS:Thre...

journal_title：Digestion

authors： Scharl M,Geisel S,Vavricka SR,Rogler G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIM:Reddish depressed lesions (RDLs) frequently observed in patients following Helicobacter pylori eradication are indistinguishable from gastric cancer. We examined the clinical and histological feature of RDLs and its relevant endoscopic diagnosis including magnifying narrow-band imaging (M-NBI). METH...

journal_title：Digestion

authors： Kotachi T,Ito M,Boda T,Kiso M,Masuda K,Hata K,Kawamura T,Sanomura Y,Yoshihara M,Tanaka S,Chayama K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:We investigated the effects of indomethacin and rebamipide on the gut microbiota profiles using terminal restriction fragment polymorphism (T-RFLP) analysis. MATERIALS AND METHODS:Female C57BL/6J mice were given indomethacin (10 mg/kg, s.c.) once a day and 2.5 mg rebamipide orally 3 times a day. After ...

journal_title：Digestion

authors： Imaeda H,Fujimoto T,Takahashi K,Kasumi E,Fujiyama Y,Andoh A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma (CCA) is the most common hepatobiliary malignancy complicating primary sclerosing cholangitis (PSC). Unfortunately, timely diagnosis of CCA in PSC patients remains challenging. AIM:To investigate the strategies among liver centers regarding pre-transplant screening for CCA in patients wit...

journal_title：Digestion

authors： Trilianos P,Selaru F,Li Z,Gurakar A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Endoscopic definitions and management of Barrett's esophagus vary widely among countries. To examine the current situation regarding diagnosis, epidemiology, management and treatment of Barrett's esophagus in East Asian countries using a questionnaire-based survey. METHODS:Representative members of the...

journal_title：Digestion

authors： Ishimura N,Amano Y,Sollano JD,Zhu Q,Kachintorn U,Rani AA,Hahm KB,Takahashi S,Arakawa T,Joh T,Matsumoto T,Naito Y,Suzuki H,Ueno F,Fukudo S,Fujiwara Y,Kamiya T,Uchiyama K,Kinoshita Y,IGICS Study Group.

更新日期：2012-01-01 00:00:00

abstract：:The treatment of malignant neuroendocrine gut and pancreatic tumors provides a therapeutic challenge. Surgery as well as medical treatment rarely cure the patient at this stage. Symptoms related to secretory products from the tumor might be life-threatening or at least reduce the quality of life considerably. Interfer...

journal_title：Digestion

authors： Oberg K,Eriksson B,Janson ET

更新日期：1994-01-01 00:00:00

abstract：AIM:To evaluate number and quality of publications in gastroenterology, hepatology and digestive endoscopy from Western Europe (Belgium, Denmark, France, Germany, Great Britain, Italy, the Netherlands, Spain, Sweden, Switzerland), Japan and USA over a recent 5-year period. METHODS:We screened by computer for full live...

journal_title：Digestion

authors： Sorrentino D,De Biase F,Trevisi A,Bartoli E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) stimulates proliferation, migration and morphogenesis of epithelial cells by specific binding to its receptor c-met. Overexpression of HGF or c-met has been reported for human gastric or pancreatic cancer. In colorectal cancer overexpression of c-met but not HGF has been shown....

journal_title：Digestion

authors： Otte JM,Schmitz F,Kiehne K,Stechele HU,Banasiewicz T,Krokowicz P,Nakamura T,Fölsch UR,Herzig K

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate genotyping for two DNA variants (c.1993+327C>T and c.1438+117G>A), recently found to be associated with adult-type hypolactasia, in the diagnosis of lactose intolerance. METHODS:In total, 166 consecutive patients with gastrointestinal symptoms mimicking hypolactasia admitted to the clin...

journal_title：Digestion

authors： Büning C,Genschel J,Jurga J,Fiedler T,Voderholzer W,Fiedler EM,Worm M,Weltrich R,Lochs H,Schmidt H,Ockenga J

更新日期：2005-01-01 00:00:00

abstract：:Isolated acinar cells from rat pancreas responded well to hormonal treatment. Both secretin (synthetic and highly purified from porcine origin) and CCK-octapeptide stimulated amylase secretion in these cells. The response in both cases was very rapid. A maximal output of enzyme was reached within 5-10 min after the ad...

journal_title：Digestion

authors： Lee PC

更新日期：1979-01-01 00:00:00

abstract：:It is now generally admitted that phytohemagglutinin (PHA) constitutes the main factor responsible for the dietary toxicity of raw kidney beans. In the growing rat, an impairment of growth is the unique expression of a malnutrition syndrome. The aim of this work was to precise to what extent the intestinal injuries ma...

journal_title：Digestion

authors： Lafont J,Rouanet JM,Gabrion J,Assouad JL,Zambonino Infante JL,Besançon P

更新日期：1988-01-01 00:00:00