Scientific publications in gastroenterology and hepatology in Western Europe, USA and Japan in the years 1992-1996: a global survey.

abstract：BACKGROUND AND AIMS:To evaluate genotyping for two DNA variants (c.1993+327C>T and c.1438+117G>A), recently found to be associated with adult-type hypolactasia, in the diagnosis of lactose intolerance. METHODS:In total, 166 consecutive patients with gastrointestinal symptoms mimicking hypolactasia admitted to the clin...

journal_title：Digestion

authors： Büning C,Genschel J,Jurga J,Fiedler T,Voderholzer W,Fiedler EM,Worm M,Weltrich R,Lochs H,Schmidt H,Ockenga J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Several earlier studies on factors predicting the long-term outcome of ulcerative colitis only encompassed treatment failure for one severe episode, or suffered from a lack of multivariate analyses. We aimed to identify factors assessable at diagnosis or after the first induction therapy which predicted...

journal_title：Digestion

authors： Shiga H,Takagi S,Inoue R,Kinouchi Y,Ohkubo T,Takahashi S,Negoro K,Yokoyama H,Kato S,Fukushima K,Hiwatashi N,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：:A 14C-triolein breath test was carried out on 49 subjects suffering from chronic pancreatitis or from other digestive diseases, and its results were compared with the daily fecal fat excretion. The 14CO2 peak excretion was abnormal in all the subjects with a fecal fat excretion above 14 g/day, whereas individual value...

journal_title：Digestion

authors： Benini L,Scuro LA,Menini E,Manfrini C,Vantini I,Vaona B,Brocco G,Talamini G,Cavallini G

更新日期：1984-01-01 00:00:00

abstract：:The current therapy of choice for all Helicobacter pylori-associated ulcer disease is eradication therapy. Although adequate therapeutic regimens are currently available, often still ineffective therapies are tried. Cure of the infection essentially eliminates the ulcer diathesis. Cure of the infection is especially i...

journal_title：Digestion

authors： Tytgat GN

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND AIM:Along with the widespread use of eradication for Helicobacter pylori (H. pylori), the incidence of gastric cancer after eradication has also been increasing. There is a need for clarification of the clinical and biological characteristics of these neoplasms. PATIENTS AND METHODS:We studied 27 cases ...

journal_title：Digestion

authors： Matsuo T,Ito M,Tatsugami M,Boda T,Takata S,Tanaka S,Chayama K

更新日期：2012-01-01 00:00:00

abstract：AIMS:To evaluate the prevalence of proximal reflux and esophago-bronchial reflex (EBR) in patients with asthma, and to compare the symptom spectrum, esophageal acid sensitivity, pH monitoring, and the endoscopic and manometric parameters of EBR-positive and -negative patients with asthma. PATIENTS AND METHODS:Forty-th...

journal_title：Digestion

authors： Rosztóczy A,Makk L,Izbéki F,Róka R,Somfay A,Wittmann T

更新日期：2008-01-01 00:00:00

abstract：:Eighteen cases of severe hyperplasia of fundic argyrophil cells observed during routine histologic examination of endoscopic gastric biopsy specimens from unselected patients with upper gastro-intestinal symptomatology were investigated. All patients, except one, were female with a mean age of 57 years. Atrophic gastr...

journal_title：Digestion

authors： Bordi C,Pilato F,Carfagna G,Ferrari C,D'Adda T,Sivelli R,Bertelé A,Missale G

更新日期：1986-01-01 00:00:00

abstract：:Cholecystokinin (CCK) is known to inhibit gastric acid secretion and gastric emptying but its physiological role in the inhibition of gastric functions is not settled. In this study performed on 16 young male subjects, gastric acid secretion and emptying rate were determined after intragastric administration of 8% pep...

journal_title：Digestion

authors： Konturek SJ,Kwiecien N,Obtulowicz W,Kopp B,Oleksy J,Rovati L

更新日期：1990-01-01 00:00:00

abstract：:The effects of secretin and caerulein on the absorption of water, sodium, potassium and glucose from the jejunum of dogs were investigated. Intravenous infusion of 1 clinical unit (CU; 82 pmol/kg/h) of secretin inhibited jejunal absorption of water, sodium and glucose compared to control period. Adding an intravenous ...

journal_title：Digestion

authors： Hirose S,Shimazaki K,Hattori N

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:At present, benefits of surgical resection and appropriate selection criteria in patients affected by both hepatic and pulmonary metastases of colorectal cancer (CRC) are under discussion. Our analysis focused on a surgical series of such patients and our final aim consisted in identifying potential pro...

journal_title：Digestion

authors： Zizzo M,Galeone C,Braglia L,Ugoletti L,Siciliani A,Nachira D,Margaritora S,Pedrazzoli C,Paci M,Lococo F

更新日期：2020-01-01 00:00:00

abstract：:The effect of the interruption of the enterohepatic circulation on bile production in anesthetized rats both before and after two thirds partial hepatectomy (PH) was studied. Both in the control animals and in the different periods after PH, interruption of the enterohepatic circulation led to significant decreases in...

journal_title：Digestion

authors： Pérez-Barriocanal F,González J,Esteller A

更新日期：1986-01-01 00:00:00

abstract：:This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

journal_title：Digestion

authors： Raul F,Galluser M,Doffoel M

更新日期：1984-01-01 00:00:00

abstract：:Previous studies suggested that gastrin-releasing peptide (a neuropeptide found in rat oxyntic mucosa) and oxyntomodulin (a glucagon-containing peptide of mammalian gut) could directly affect the acid secretion of the parietal cells. We therefore studied their effect on gastric acid production in vitro by measuring [1...

journal_title：Digestion

authors： Gehl J,Jeppesen JL,Poulsen SS,Holst JJ

更新日期：1988-01-01 00:00:00

abstract：:Rectal biopsies were maintained in organ culture over a 24-hour culture period, with good preservation of histological architecture. A filtrate containing Clostridium difficile toxin significantly inhibited the rise in epithelial alkaline phosphatase activity normally seen during culture. This effect was abolished by ...

journal_title：Digestion

authors： Allan A,Jewell DP

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:Defective epithelial barrier has been implicated in the pathogenesis of irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was to investigate gut permeability in patients with inactive ulcerative colitis (UC) and in patients with IBS. METHODS:IBS patients of the diarr...

journal_title：Digestion

authors： Gecse K,Róka R,Séra T,Rosztóczy A,Annaházi A,Izbéki F,Nagy F,Molnár T,Szepes Z,Pávics L,Bueno L,Wittmann T

更新日期：2012-01-01 00:00:00

abstract：:Lecithin: cholesterol acyltransferase activity has been measured in serum from patients with various liver disorders and positive LP-X tests and from healthy subjects. Statistical analysis indicated that lecithin: cholesterol acyltransferase activity provided no help in the discrimination between the persons of both g...

journal_title：Digestion

authors： Jung K,Schimmelpfennig W,Wack R,Neumann R

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:The present study aimed to evaluate the micronucleus (MN), nucleoplasmic bridges (NPBs) and nuclear buds (NBUDs) in the mitogen-stimulated lymphocytes of patients with ulcerative colitis (UC). In addition, we assessed MN frequency in exfoliated colonic epithelial cells obtained from both the diseased and heal...

journal_title：Digestion

authors： Karaman A,Hamurcu Z,Donmez H,Bitken N,Karaman H,Baskol M,Gursoy S,Guven K,Ozbakir O,Yucesoy M

更新日期：2012-01-01 00:00:00

abstract：:Refractory chronic diarrhea that does not respond to specific antimicrobial therapy or standard unspecific medication may present a challenging and serious clinical problem. Octreotide is a candidate drug for the treatment of these patients as it inhibits gastrointestinal motility, pancreatic secretion and inhibits in...

journal_title：Digestion

authors： Fried M

更新日期：1999-01-01 00:00:00

abstract：:The pancreatic exocrine secretory response to increasing doses of exogenous caerulein with and without a background infusion of secretin was studied in 5 healthy volunteers. Caerulein over a full range of doses (2.3-37 pmol/kg/h) produced increasing enzyme secretion up to 18.5 pmol/kg/h, whereas 37 pmol/kg/h was clear...

journal_title：Digestion

authors： Beglinger C,Köhler E,Stalder GA,Jansen J,Gyr K

更新日期：1986-01-01 00:00:00

abstract：:Leukocyte infiltration in the pancreas is involved in the aggravation of acute pancreatitis from edematous phase into necrotic change, and mild disease into severe disease; however, the mechanism responsible for leukocyte accumulation is not fully understood. This study was designed to clarify the mechanism underlying...

journal_title：Digestion

authors： Yamauchi J,Sunamura M,Shibuya K,Takeda K,Kobari M,Matsuno S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:The pathogenesis of dyspeptic/reflux symptoms and the clinico-pathologic profile of affected patients are still poorly understood. To improve our knowledge in this field we carried out a systematic, comparative analysis of symptom profiles and histopathologic patterns of oesophagogastroduodenal mucosa i...

journal_title：Digestion

authors： Villani L,Trespi E,Fiocca R,Broglia F,Colla C,Luinetti O,Tinelli C,Solcia E

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:Despite the high prevalence of obstructive sleep apnea syndrome (OSAS), most individuals are unaware of its diagnosis. We assessed whether an upper gastrointestinal (GI) endoscopy can accurately predict the incidence of OSAS. METHODS:After endoscopic evaluation of laryngo-pharyngeal collapse, a total o...

journal_title：Digestion

authors： Ohata K,Sakai E,Nakao T,Kimoto Y,Ishii R,Konishi T,Ueno S,Takita M,Negishi R,Morinushi T,Muramoto T,Matsuhashi N,Nakaya T,Koba I,Nakaji S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Although pain is the most feared part of the terminal life of many patients with cancer, the intensity and the quality of the pain is all too often only scantly described. METHOD:The quality and quantity of pain were prospectively registered by five variables, including a visual analogue scale (VAS), in 46 ...

journal_title：Digestion

authors： Grahm AL,Andrén-Sandberg A

更新日期：1997-01-01 00:00:00

abstract：:Mechanisms of antisecretory action of intragastric FPL-52694, a mast cell stabilizer, were investigated in anesthetized rats. In Schild's rat preparation, intravenous FPL-52694 (10 mg/kg) significantly suppressed acid secretion in response to only tetragastrin (20 micrograms/kg, i.v.) (42.1 +/- 19.4%), while intragast...

journal_title：Digestion

authors： Takeuchi K,Ueki S,Okabe S

更新日期：1986-01-01 00:00:00

abstract：:Prostacyclin, its stable metabolite 6-keto-prostaglandin F1 alpha and prostaglandin E2 were tested on the adenylate cyclase system in human gastric mucosa. All three compounds were able to activate human cyclase. Saturating concentrations of prostacyclin, prostaglandin E2 and 6-keto-prostaglandin F1 alpha (each 0.28 m...

journal_title：Digestion

authors： Simon B,Kather H

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:An abnormal immune response may play a pathogenetic role in chronic pancreatitis. However, to date characterization of the systemic immunological changes in patients with chronic pancreatitis has not been undertaken. METHODS:Lymphocyte phenotypes and proliferation ((3)H-thymidine) after stimulation with mit...

journal_title：Digestion

authors： Ockenga J,Jacobs R,Kemper A,Benschop RJ,Schmidt RE,Manns MP

更新日期：2000-01-01 00:00:00

abstract：:Electrophoretic studies of inactive ductal pancreatic secretions, collected on five successive days following operation, demonstrated up to 18 protein bands. Comparison of the densitometric scans on the first and fourth days was as follows: the patterns from different individuals appeared similar during the periods of...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

journal_title：Digestion

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-11-18 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：:Different materials dissolved in 0.9% NaCl were injected into the connective, interlobular tissue of the duodenal part of the rat pancreas. Activated rat pancreatic juice or trypsin were able to induce localized necrohemorrhagic pancreatitis. Only mild edema and leukocytic infiltration were observed after injecting bo...

journal_title：Digestion

authors： Odaira C,Berger Z,Iovanna JL,Sarles H

更新日期：1986-01-01 00:00:00