Extensive small bowel resection in the rat: lack of effect on serum proteins.

Abstract:

:Rats were subjected to serial venesections 3 days prior to and then sequentially for 4 weeks after surgical removal of either the proximal or distal half of the small bowel. Total serum protein concentration and protein electrophoretic patterns were determined on these sera. Both sham-operated and unoperated animals served as controls. The data showed differences in serum proteins in the first week after operation between the three groups of operated rats and the unoperated controls. However, there were no significant differences in serum proteins between the sham-operated and the two types of resected animals. This indicates that the combined effects of laparotomy, anesthesia, pre- and postoperative fasting outweighed any additional early effects of loss of 50% small bowel on serum proteins. The study also demonstrates the necessity of having both unoperated and sham-operated control groups in designing experiments involving surgical extirpation of intestine.

journal_name

Digestion

journal_title

Digestion

authors

Urban E,Ricks PM

doi

10.1159/000198408

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

1-7

issue

1

eissn

0012-2823

issn

1421-9867

journal_volume

20

pub_type

杂志文章
  • Nutritional modulation of the inflammatory bowel response.

    abstract::Crohn's disease and ulcerative colitis represent distinct phenotypic forms of inflammatory bowel disease and continue to be a common cause of morbidity. The corticosteroids and the immunomodulatory drugs, which are the basis of treatment for the inflammatory bowel diseases, do not assure always satisfactory outcomes. ...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000323456

    authors: Ioannidis O,Varnalidis I,Paraskevas G,Botsios D

    更新日期:2011-01-01 00:00:00

  • A Novel Noninvasive Method for Quantitative Detection of Colonic Dysmotility Using Real-Time Ultrasonography.

    abstract:INTRODUCTION:Colonic motility disorders are a frequent clinical problem caused by various drugs and diseases. However, the etiology of colonic dysmotility is often unclear due to the lack of in vivo methods, including rapid dynamic assessment. OBJECTIVES:The aim of this study was to establish a novel quantitative meth...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000511851

    authors: Kishi K,Kaji N,Tsuru Y,Hori M

    更新日期:2020-12-01 00:00:00

  • Sedation training using a human patient simulator.

    abstract::High-fidelity simulation uses simulators that combine all of the physiological and pharmacological responses of a human in a manikin. These simulators change and respond to the users and trainees. Using simulators for teaching sedation in the field of gastroenterology unifies all the advantages of manikins. To underst...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000287214

    authors: Hofmann N,Datz C,Schöchl H

    更新日期:2010-01-01 00:00:00

  • Human chorionic gonadotropin-beta in the differentiation of malignancy-related and nonmalignant ascites.

    abstract::The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201324

    authors: Gerbes AL,Hoermann R,Mann K,Jüngst D

    更新日期:1996-01-01 00:00:00

  • Effect of secretin on intestinal monosaccharide absorption and new water movement in the rat.

    abstract::Repeated intravenous injections of 2.0 clinical units (CU) secretin per kg body weight showed no effect on jejunal glucose absorption and net water movement in perfusion studies in vivo. The in vitro uptake of galactose and 3-O-methylglucose was not altered by a secretin load given 12 min before sacrifice. The values ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000197730

    authors: Böhmer R,Rommel K

    更新日期:1975-01-01 00:00:00

  • Effect of intestinal diamine oxidase (DAO) depletion by heparin on mucosal polyamine metabolism.

    abstract::The aim of this study was to examine the relative importance of the enzymes ornithine decarboxylase (ODC) and diamine oxidase (DAO) in intestinal polyamine metabolism in normal rats. To study this we measured jejunal and ileal DAO and ODC activities and polyamine levels 2 h after injecting, in non-fasting male Wistar ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000200411

    authors: Rokkas T,Vaja S,Taylor P,Murphy GM,Dowling RH

    更新日期:1990-01-01 00:00:00

  • Functional changes of the exocrine perfused rat pancreas in cerulein-induced pancreatitis.

    abstract::Functional changes of the exocrine pancreas in cerulein-induced pancreatitis were evaluated with the isolated perfused rat pancreas. In control specimens (n = 7), baseline pancreatic juice volume was 0.23 +/- 0.06 microliter/min and after stimulation with CCK-8 (10(-10) M) and secretin (10(-10) M), it was 2.26 +/- 0.4...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000200879

    authors: Ando K,Manabe T,Kyogoku T,Ohshio G,Yotsumoto F,Tamura K,Imanishi K,Yositomi S,Tobe T

    更新日期:1992-01-01 00:00:00

  • Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats.

    abstract::The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199903

    authors: Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

    更新日期:1989-01-01 00:00:00

  • Evaluation of the 75Se-l-selenomethionine test for pancreatic disease. Studies on gel filtration.

    abstract::Radioselenium-secretin-pancreozymin tests have been performed in 22 normal subjects and in 23 patients with pancreatic exocrine insufficiency. Each subject received an intravenous injection of 40-100 mu Ci 75Se-l-selenomethionine as a bolus which was followed by an intravenous infusion of secretin-CCK-PZ (1 CU/kg/h) f...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198444

    authors: Pointner H,Kletter K

    更新日期:1980-01-01 00:00:00

  • True adenomas of the cardia: a case series of 3 patients.

    abstract:BACKGROUND/AIM:True adenomas of the cardia appear to be extremely rare lesions. There are no data on the natural history and histopathological background of these lesions. We report 3 patients with true adenomas of the cardia. METHODS AND RESULTS:Three patients with polypoid masses at the cardia below the Z-line were ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000121413

    authors: Bajbouj M,von Weyhern C,Becker V,Seidl S,Ott R,Schatke W,Fend F,Schmid RM,Meining A

    更新日期:2008-01-01 00:00:00

  • Gastrin and gastric enterochromaffin-like cell carcinoids in the rat.

    abstract::Life-long administration (greater than or equal to 2 years) of a number of long-acting gastric acid inhibitors (including H2-receptor antagonists, omeprazole and ciprofibrate) has been associated with the development of gastric enterochromaffin-like cell (ECL cell) carcinoids in rats. It has been postulated that they ...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000200510

    authors: Carlsson E,Havu N,Mattsson H,Ekman L

    更新日期:1990-01-01 00:00:00

  • Fate of pancreatic enzymes in the human intestinal lumen in health and pancreatic insufficiency.

    abstract::The activities of pancreatic enzymes decrease during their passage from the duodenum to the terminal ileum, but degradation rates of individual enzymes are different. Whereas lipase activity is lost most rapidly, proteases and amylase are more stable. The mechanism by which lipase activity is destroyed is proteolysis,...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000201097

    authors: Layer P,Gröger G

    更新日期:1993-01-01 00:00:00

  • Chromoendoscopy is a valuable tool for screening of high-risk patients with head and neck cancer for early detection of esophageal cancer.

    abstract:BACKGROUND:The incidence of esophageal cancer is markedly increased in patients with head and neck cancer, and the presence of esophageal cancer is associated with reduced survival rates. AIMS:We investigated whether the results of screening for esophageal cancer in patients with head and neck cancer using chromoendos...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000094523

    authors: Moschler O,Spahn TW,Middelberg-Bisping C,Grosse-Thie W,Christoph B,Kloeppel G,Mueller MK

    更新日期:2006-01-01 00:00:00

  • Changes in glycoproteins of liver plasma membranes from rats treated with D-galactosamine.

    abstract::D-Galactosamine administration to rats (400 mg/kg) by intraperitoneal injection induced biochemical alterations in liver plasma membranes. Alterations were studied 4, 16 and 24 h after D-galactosamine injection. Plasma membrane 5'-mononucleotidase activity decreased to 40% of control values. Carbohydrate composition w...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198373

    authors: Bertrand F,Veissiere D,Picard J

    更新日期:1979-01-01 00:00:00

  • Endoscopic Ultrasound Elastography as a Novel Diagnostic Method for the Assessment of Hardness and Depth of Invasion in Colorectal Neoplasms.

    abstract:INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000511589

    authors: Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

    更新日期:2020-11-18 00:00:00

  • Voglibose (AO-128) is an efficient alpha-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve.

    abstract::The alpha-glucosidase inhibitor voglibose (AO-128) was designed to prevent rapid postprandial blood glucose rises in non-insulin-dependent diabetics. We analyzed its effect on the entero-insular axis in 72 healthy volunteers in a double-blind study design before, after the 1st dose, and on the 7th day of a 7-day treat...

    journal_title:Digestion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000201282

    authors: Göke B,Fuder H,Wieckhorst G,Theiss U,Stridde E,Littke T,Kleist P,Arnold R,Lücker PW

    更新日期:1995-01-01 00:00:00

  • Doxycycline in Eradication Therapy of Helicobacter pylori--a Systematic Review and Meta-Analysis.

    abstract:BACKGROUND:Since resistance of Helicobacter pylori is developing very fast all over the world, new treatment regimens for eradication are urgently needed. AIM:To compare eradication success rate of H. pylori treatment regimens with and without doxycycline. METHODS:English medical literature searches were conducted fo...

    journal_title:Digestion

    pub_type: 杂志文章,meta分析,评审

    doi:10.1159/000443683

    authors: Niv Y

    更新日期:2016-01-01 00:00:00

  • Constitutive nitric oxide synthases in rat gastric mucosa: subcellular distribution, relative activity and different carboxyl-terminal antigenicity of the neuronal form compared with cerebellum.

    abstract:BACKGROUND/AIMS:To investigate whether the neuronal form of nitric oxide (NO) synthase (nNOS) in gastric mucosa differed from nNOS in the brain in subcellular distribution or antigenicity, and to determine the relative activity of the endothelial form of NO synthase (eNOS) and nNOS in gastric mucosa. METHODS:Subcellul...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007507

    authors: Price K,Hanson P

    更新日期:1998-07-01 00:00:00

  • Safety experience from long-term treatment with omeprazole.

    abstract::Omeprazole was administered for up to 6 years in 859 patients for 'prevention of relapse in patients with poorly responsive peptic ulcer or reflux oesophagitis'. The pattern of adverse events reported during long-term treatment was similar to the adverse-event profile in short-term treatment with omeprazole (n = 2,818...

    journal_title:Digestion

    pub_type: 杂志文章,meta分析

    doi:10.1159/000200922

    authors: Joelson S,Joelson IB,Lundborg P,Walan A,Wallander MA

    更新日期:1992-01-01 00:00:00

  • Octreotide in the treatment of refractory diarrhea.

    abstract::Refractory chronic diarrhea that does not respond to specific antimicrobial therapy or standard unspecific medication may present a challenging and serious clinical problem. Octreotide is a candidate drug for the treatment of these patients as it inhibits gastrointestinal motility, pancreatic secretion and inhibits in...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000051479

    authors: Fried M

    更新日期:1999-01-01 00:00:00

  • Efficacy of Upper Gastrointestinal Endoscopic Examination to Identify Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Cross-Sectional Study.

    abstract:BACKGROUND/AIMS:Despite the high prevalence of obstructive sleep apnea syndrome (OSAS), most individuals are unaware of its diagnosis. We assessed whether an upper gastrointestinal (GI) endoscopy can accurately predict the incidence of OSAS. METHODS:After endoscopic evaluation of laryngo-pharyngeal collapse, a total o...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000491385

    authors: Ohata K,Sakai E,Nakao T,Kimoto Y,Ishii R,Konishi T,Ueno S,Takita M,Negishi R,Morinushi T,Muramoto T,Matsuhashi N,Nakaya T,Koba I,Nakaji S

    更新日期:2019-01-01 00:00:00

  • Pharmacological effect of somatostatin on bile secretion in man.

    abstract::Somatostatin (SST) has been shown to induce cholestasis in the dog and in the rat. In man, it is still unknown whether SST modifies bile formation. The present study was undertaken to examine the influence of SST on bile secretion in man. Two volunteers who had a total external biliary fistula received 1-hour SST infu...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199820

    authors: Marteau P,Chrétien Y,Calmus Y,Parc R,Poupon R

    更新日期:1989-01-01 00:00:00

  • Metal absorption and the intestinal mucus layer.

    abstract::The luminal mucus layer of the rat's small intestine was separated from the mucosa by filling the lumen with agar jelly. When the rats were fasted overnight and given 59Fe or 65Zn by stomach tube the mucus isolated by this technique contained more isotope and more sialic acid than fed controls, and more of the isotope...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199480

    authors: Quarterman J

    更新日期:1987-01-01 00:00:00

  • Effect of cell proliferation on healing of gastric and duodenal ulcers in rats.

    abstract::The healing of acetic acid-induced gastric and duodenal ulcers was examined together with the biochemical indices of growth in gastric and duodenal mucosa in the following three groups of rats: (a) chow-fed, (b) fed an isocaloric liquid diet, (c) fed the liquid diet plus pentagastrin injections (250 micrograms/kg, 3 t...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199280

    authors: Takeuchi K,Johnson LR

    更新日期:1986-01-01 00:00:00

  • Gastric carcinoid with histamine production, histamine transporter and expression of somatostatin receptors.

    abstract::A case of sporadic, histamine-producing gastric carcinoid with liver metastases is reported. The patient was treated with somatostatin analogue (octreotide) combined with cortisone and blockade of histamine receptors prior to surgery, which included subtotal gastrectomy, excision of lymph node metastases and superfici...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007482

    authors: Kölby L,Wängberg B,Ahlman H,Jansson S,Forssell-Aronsson E,Erickson JD,Nilsson O

    更新日期:1998-01-01 00:00:00

  • Role of alimentation in irritable bowel syndrome.

    abstract:BACKGROUND:Different food items are made responsible for irritable bowel syndrome (IBS) symptoms, but the physiopathology of IBS remains unclear. AIMS:During a meeting in Nice, France, experts of the European Working Team of the IBiS Club discussed selected data regarding the relationships between alimentation, food i...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000072061

    authors: Dapoigny M,Stockbrügger RW,Azpiroz F,Collins S,Coremans G,Müller-Lissner S,Oberndorff A,Pace F,Smout A,Vatn M,Whorwell P

    更新日期:2003-01-01 00:00:00

  • Evolution of biliary secretion during bile diversion in normal and two-thirds hepatectomized rats.

    abstract::The effect of the interruption of the enterohepatic circulation on bile production in anesthetized rats both before and after two thirds partial hepatectomy (PH) was studied. Both in the control animals and in the different periods after PH, interruption of the enterohepatic circulation led to significant decreases in...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199360

    authors: Pérez-Barriocanal F,González J,Esteller A

    更新日期:1986-01-01 00:00:00

  • Impact of histopathology on the outcome of D1/D2 gastrectomies with R0 resection.

    abstract:AIMS:The primary objective of this study was to clarify the influence of histotype on the outcome of D1/D2 gastrectomized patients with pathologically proven R0 resection. The secondary objective was to demonstrate overall survival (OS), disease-free survival (DFS), and locoregional recurrence rates following standard ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000338298

    authors: Uslu A,Bati H,Postaci H,Nart A,Eliyatkin N,Yetis H,Corumlu B,Aykas A,Zengel B

    更新日期:2012-01-01 00:00:00

  • Duodenal toxicity of dietary Phaseolus vulgaris lectins in the rat: an integrative assay.

    abstract::It is now generally admitted that phytohemagglutinin (PHA) constitutes the main factor responsible for the dietary toxicity of raw kidney beans. In the growing rat, an impairment of growth is the unique expression of a malnutrition syndrome. The aim of this work was to precise to what extent the intestinal injuries ma...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199736

    authors: Lafont J,Rouanet JM,Gabrion J,Assouad JL,Zambonino Infante JL,Besançon P

    更新日期:1988-01-01 00:00:00

  • Omeprazole in the treatment of Zollinger-Ellison syndrome and histamine H2-antagonist refractory ulcers.

    abstract::Omeprazole is a very potent and long-acting inhibitor of gastric acid secretion. These characteristics make the drug very suitable for the management of gastric acid hypersecretion and symptom relief in patients with the Zollinger-Ellison syndrome, and in the treatment of patients with ulcers resistant to histamine H2...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000200102

    authors: Meijer JL,Jansen JB,Lamers CB

    更新日期:1989-01-01 00:00:00