Abstract:
BACKGROUND/AIM:True adenomas of the cardia appear to be extremely rare lesions. There are no data on the natural history and histopathological background of these lesions. We report 3 patients with true adenomas of the cardia. METHODS AND RESULTS:Three patients with polypoid masses at the cardia below the Z-line were submitted to a tertiary referral center for further diagnosis and therapy. In 2 of the 3 cases Barrett's esophagus with low-grade intraepithelial neoplasia was assumed on the basis of histopathological examination of biopsy specimens taken from the surface of the lesions. Polypectomy was performed in all 3 cases. In 2 of the 3 cases the final histopathological diagnosis of low-grade adenoma of the cardia could only be established after complete removal of the polypoid masses. CONCLUSIONS:Adenomas of the cardia can be mistaken for dysplasia arising from Barrett's esophagus, if the diagnosis is based on endoscopic biopsies only. It is, therefore, reasonable to completely remove any suspicious lesions by endoscopy not only for therapeutic but also for diagnostic reasons.
journal_name
Digestionjournal_title
Digestionauthors
Bajbouj M,von Weyhern C,Becker V,Seidl S,Ott R,Schatke W,Fend F,Schmid RM,Meining Adoi
10.1159/000121413subject
Has Abstractpub_date
2008-01-01 00:00:00pages
65-7issue
1eissn
0012-2823issn
1421-9867pii
000121413journal_volume
77pub_type
杂志文章相关文献
DIGESTION文献大全abstract::Several previous studies have shown that the plasma concentration of gamma-amino-butyric acid (GABA) is markedly increased in patients with hepatic encephalopathy, and it has been suggested that decreased metabolism of peripheral GABA might contribute to the cerebral dysfunctions observed. In the present study, plasma...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000200724
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) has become the standard endoscopic treatment for early gastric cancer without lymph node metastasis. At present, undifferentiated type intramucosal cancers without ulcer findings <20 mm in size are often chosen as endoscopic treatment lesions for expanded indication. Th...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000334681
更新日期:2012-01-01 00:00:00
abstract::Cell renewal in the duodenal mucosa of Mastomys was studied by autoradiography 1 and 24 h after intraperitoneal injection of tritiated thymidine. Non-specific duodenitis and duodenal ulceration were produced with a continuous infusion of histamine. Mucosal renewal in the duodenum of 30 control Mastomys was compared wi...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000200226
更新日期:1990-01-01 00:00:00
abstract::The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201324
更新日期:1996-01-01 00:00:00
abstract::Radioselenium-secretin-pancreozymin tests have been performed in 22 normal subjects and in 23 patients with pancreatic exocrine insufficiency. Each subject received an intravenous injection of 40-100 mu Ci 75Se-l-selenomethionine as a bolus which was followed by an intravenous infusion of secretin-CCK-PZ (1 CU/kg/h) f...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198444
更新日期:1980-01-01 00:00:00
abstract::After two decades of progress the best current approach to treatment of Helicobacter pylori infection is a strategy that combines two consecutive complementary treatments. Current guidelines recommend a first-line triple therapy - 7-10 days of a proton-pump inhibitor (PPI), clarithromycin and amoxicillin - followed by...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000089787
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIM:Cutaneous electrical stimulation has been reported to be as effective as electroacupuncture. The aim of this study was to test whether cutaneous electrical stimulation had the same effect as electroacupuncture to enhance the regularity of myoelectrical activity. METHODS:Fifteen healthy male volunteers w...
journal_title:Digestion
pub_type: 临床试验,杂志文章
doi:10.1159/000065596
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIM:Diarrhoea in collagenous colitis has been considered as secretory though the pathophysiology has been studied thoroughly in only a few patients. The result of fasting is one way to distinguish between secretory and osmotic diarrhoea. Our aim was to investigate the effect of fasting on diarrhoea in collag...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000051928
更新日期:2002-01-01 00:00:00
abstract::The treatment of malignant neuroendocrine gut and pancreatic tumors provides a therapeutic challenge. Surgery as well as medical treatment rarely cure the patient at this stage. Symptoms related to secretory products from the tumor might be life-threatening or at least reduce the quality of life considerably. Interfer...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000201204
更新日期:1994-01-01 00:00:00
abstract::The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201079
更新日期:1993-01-01 00:00:00
abstract::Life-long administration (greater than or equal to 2 years) of a number of long-acting gastric acid inhibitors (including H2-receptor antagonists, omeprazole and ciprofibrate) has been associated with the development of gastric enterochromaffin-like cell (ECL cell) carcinoids in rats. It has been postulated that they ...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000200510
更新日期:1990-01-01 00:00:00
abstract::In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201423
更新日期:1997-01-01 00:00:00
abstract::Gastro-oesophageal reflux disease (GORD) is a chronic illness causing recurrent typical and atypical symptoms. Possible complications include oesophagitis, ulcer, stricture and Barrett's oesophagus. Evidence suggests that the intraoesophageal pH correlates directly with the degree of mucosal injury. Proton pump inhibi...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000076371
更新日期:2004-01-01 00:00:00
abstract::There is no generally accepted treatment in the irritable bowel syndrome (IBS), probably because of a lack of convincing therapeutic trials. In the present study, 120 outpatients with IBS participated in a prospective randomized therapeutic trial. According to a double-blind design, 40 patients received 400 mg/day meb...
journal_title:Digestion
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000199329
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Cytomegalovirus (CMV) infection exacerbates ulcerative colitis (UC) refractory to immunosuppressive therapies (IMT). However, the underlying UC remained active in some UC patients, despite the fact that CMV-DNA in colonic mucosa became negative after antiviral therapy. Therefore, new therapeutic strategies f...
journal_title:Digestion
pub_type: 杂志文章,多中心研究
doi:10.1159/000321911
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/AIMS:Polyamine uptake from the circulation plays an important role in the maintenance of the intracellular polyamine content during extensive proliferation in intestinal mucosal cells. METHODS:Isolated basolateral membrane vesicles of the rabbit enterocyte were used to characterize polyamine transport acros...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000007468
更新日期:1998-01-01 00:00:00
abstract::Chornic exogenous administration of cholecystokinin octapeptide (CCK8) to rats led to a reduced sensitivity of pancreatic acinar cells to both CCK8 and carbachol stimulation without changes in affinity or number of CCK or muscarinic receptors. In addition, repeated feeding of camostate, a synthetic protease inhibitor ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000200386
更新日期:1990-01-01 00:00:00
abstract::By immunohistochemistry and double staining technique, almost complete coexistence of galanin-like immunoreactivity (GAL-LI) and vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) was demonstrated in submucosal ganglionic cells and mucosal nerve fibers of the porcine ileum. The release of the two neurope...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000200741
更新日期:1991-01-01 00:00:00
abstract::L-Amino acid solution given intravenously in Heidenhain pouch dogs resulted in marked changes of both basal and pentagastrin-stimulated gastric secretions. During a 1-hour amino acid infusion, a significant augmentation of pentagastrin-induced secretion was observed. A significant increase of secretion during amino ac...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198207
更新日期:1978-01-01 00:00:00
abstract::The purpose of this study was to determine the regulation of pancreatic polypeptide (PP) release by using pirenzepine (a specific M1 muscarinic receptor antagonist), 4-diphenylacetoxy-N-methylpiperidine methobromide (4-DAMP, a specific M3 muscarinic receptor antagonist), atropine (a nonspecific muscarinic receptor ant...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201168
更新日期:1994-01-01 00:00:00
abstract::We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201143
更新日期:1994-01-01 00:00:00
abstract::Sedation and analgesia is the standard of care during diagnostic and therapeutic endoscopic gastrointestinal procedures in most areas of the world. Unsedated endoscopy is feasible in selected patients, but requires commitment on the part of both the patient and the provider. The American Society of Anesthesiologists h...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000285504
更新日期:2010-01-01 00:00:00
abstract::The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alp...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199729
更新日期:1988-01-01 00:00:00
abstract::The effects of somatostatin on cholera toxin-induced secretory diarrhea and the appearance of glycoenzymes in the intestinal lumen and intestinal lymph were investigated in rat small intestine. After exposure to cholera toxin, marked fluid accumulation in the small intestinal tract and elevation of the jejunal mucosal...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199411
更新日期:1987-01-01 00:00:00
abstract::Mortality data for ulcerative colitis, Crohn's disease, and unspecified inflammatory bowel disease were examined for the countries Venezuela, Italy, and France during the decade 1969-1978. These figures were compared with similar data from England and Wales obtained from 1965 to 1975. In Italy and France deaths from C...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199040
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND/AIMS:To investigate whether the neuronal form of nitric oxide (NO) synthase (nNOS) in gastric mucosa differed from nNOS in the brain in subcellular distribution or antigenicity, and to determine the relative activity of the endothelial form of NO synthase (eNOS) and nNOS in gastric mucosa. METHODS:Subcellul...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000007507
更新日期:1998-07-01 00:00:00
abstract::The elimination of endogenous carboxyamidated and glycine-extended gastrins in liver and gut was studied before and after feeding in 14 anesthetized pigs. Before the meal, liver and gut extractions were nonsignificant. After feeding, the release rate of amidated gastrin increased from 7.5 +/- 2.6 to 21.9 +/- 5.3 pmol/...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201357
更新日期:1996-01-01 00:00:00
abstract::Compared with other imaging modalities and clinical investigation, the 111In-pentetreotide scan identified additional metastatic disease sites in 12 carcinoid patients and 2 occult primaries, and influenced the therapeutic outcome in 36 patients [29 carcinoids, 2 atypical carcinoids, 3 cancers of unknown primaries (CU...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201396
更新日期:1996-01-01 00:00:00
abstract:AIM:To evaluate number and quality of publications in gastroenterology, hepatology and digestive endoscopy from Western Europe (Belgium, Denmark, France, Germany, Great Britain, Italy, the Netherlands, Spain, Sweden, Switzerland), Japan and USA over a recent 5-year period. METHODS:We screened by computer for full live...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000007738
更新日期:2000-01-01 00:00:00
abstract:AIM:Although pectin, a dietary fibre, has been suggested to possess some trophic effects on the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the effects of pectin on rat intestinal cell proliferation and the intraluminal environment. METHODS:Control and pectin-fed rats were given a f...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000069705
更新日期:2003-01-01 00:00:00