Polyamines and the recovery of intestinal morphology and function after ischemic damage in rats.

abstract：:In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...

journal_title：Digestion

authors： Weidenbach H,Lerch MM,Turi S,Bachem M,Adler G

更新日期：1997-01-01 00:00:00

abstract：:Zinc nutriture has been studies in 30 patients with Crohn's disease using plasma zinc, hair zinc, and taste acuity as indices. Significant reductions in plasma zinc concentrations and taste acuity were seen in the patient groups as compared with normal controls. Hair zinc content was also generally low with several de...

journal_title：Digestion

authors： Solomons NW,Rosenberg IH,Sandstead HH,Vo-Khactu KP

更新日期：1977-01-01 00:00:00

abstract：:The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during i...

journal_title：Digestion

authors： Laskus T,Radkowski M,Slusarczyk J,Cianciara J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:We investigated the effects of indomethacin and rebamipide on the gut microbiota profiles using terminal restriction fragment polymorphism (T-RFLP) analysis. MATERIALS AND METHODS:Female C57BL/6J mice were given indomethacin (10 mg/kg, s.c.) once a day and 2.5 mg rebamipide orally 3 times a day. After ...

journal_title：Digestion

authors： Imaeda H,Fujimoto T,Takahashi K,Kasumi E,Fujiyama Y,Andoh A

更新日期：2012-01-01 00:00:00

abstract：:Functional changes of the exocrine pancreas in cerulein-induced pancreatitis were evaluated with the isolated perfused rat pancreas. In control specimens (n = 7), baseline pancreatic juice volume was 0.23 +/- 0.06 microliter/min and after stimulation with CCK-8 (10(-10) M) and secretin (10(-10) M), it was 2.26 +/- 0.4...

journal_title：Digestion

authors： Ando K,Manabe T,Kyogoku T,Ohshio G,Yotsumoto F,Tamura K,Imanishi K,Yositomi S,Tobe T

更新日期：1992-01-01 00:00:00

abstract：:Gastric actions of Nw-nitro-1-arginine methyl ester (L-NAME) were investigated in rats, as this agent is a reliable nitric oxide synthase inhibitor L-NAME solutions were placed in subcutaneous osmotic minipumps which continuously released L-NAME at 0.1, 1.0, 10, or 40 mg/kg/day. L-NAME dose and time-dependently enhanc...

journal_title：Digestion

authors： Qiu BS,Pfeiffer CJ,Cho CH

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) has become the standard endoscopic treatment for early gastric cancer without lymph node metastasis. At present, undifferentiated type intramucosal cancers without ulcer findings <20 mm in size are often chosen as endoscopic treatment lesions for expanded indication. Th...

journal_title：Digestion

authors： Kamada K,Tomatsuri N,Yoshida N

更新日期：2012-01-01 00:00:00

abstract：:Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity w...

journal_title：Digestion

authors： Shaw B,Wright CL

更新日期：1976-01-01 00:00:00

abstract：:108 adult patients and 34 children with chronic active hepatitis (CAH) are divided in four groups on the basis of presence and absence of hepatitis B surface antigen (HBsAg) and autoantibodies (AutoAb). There are significant differences in the numeric distribution among the four groups and the sex distribution between...

journal_title：Digestion

authors： Freudenberg J,Baumann H,Arnold W,Berger J,Büschenfelde KH

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gastric cancers are characterized by a heterogeneously hypoxic environment. Hypoxia might stimulate the malignant potential of cancer cells. The purpose of our study was to clarify the significance of hypoxia in gastric carcinoma by evaluating the expression of a hypoxic marker, namely carbonic anhydras...

journal_title：Digestion

authors： Kato Y,Yashiro M,Noda S,Kashiwagi S,Matsuoka J,Fuyuhiro Y,Doi Y,Hirakawa K

更新日期：2010-01-01 00:00:00

abstract：:The core symposiums of the Japanese Gastroenterological Association (JGA) annual scientific meetings focus on similar topics from year to year. The main topics of these symposiums for the last 3 years were centered on progress in new diagnostics and therapeutic strategies for gastrointestinal malignancy, with a specia...

journal_title：Digestion

authors： Sugiyama T

更新日期：2015-01-01 00:00:00

abstract：:Mortality data for ulcerative colitis, Crohn's disease, and unspecified inflammatory bowel disease were examined for the countries Venezuela, Italy, and France during the decade 1969-1978. These figures were compared with similar data from England and Wales obtained from 1965 to 1975. In Italy and France deaths from C...

journal_title：Digestion

authors： D'Oliveira R,Mayberry JF,Newcombe RG,Rhodes J

更新日期：1984-01-01 00:00:00

abstract：:Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...

journal_title：Digestion

authors： Jennewein HM,Hummelt H,Siewert R,Waldeck F

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:The authors reported that the repair of submucosal tissue is important in ulcer healing. The kinetics of fibroblasts have not been well known in gastric ulcer healing. The effect of subcutaneous administration of indomethacin (1 mg/kg) to submucosal tissue was also examined. METHOD:Immunohistological stainin...

journal_title：Digestion

authors： Hirose Y,Goto H,Arisawa T,Hase S,Niwa Y,Hayakawa T,Asai J,Tsukamoto Y

更新日期：1997-01-01 00:00:00

abstract：:The secretion of pancreatic polypeptide (PP) seems to be controlled by vagal cholinergic mechanisms, since both vagotomy and atropine significantly inhibit the PP response to food intake, sham feeding or insulin hypoglycaemia. In the present study, we examined the PP response to a meal after orthotopic autotransplanta...

journal_title：Digestion

authors： Köhler H,Becker HD

更新日期：1987-01-01 00:00:00

abstract：:Previous investigations have demonstrated that the cellular signaling induced by hypoxia-reoxygenation is a major pathway contributing to gastric mucosal injury induced by stress, non-steroidal anti-inflammatory drugs, and Helicobacter pylori. The aim of the present study was to perform a gene expression analysis of t...

journal_title：Digestion

authors： Katada K,Naito Y,Mizushima K,Takagi T,Handa O,Kokura S,Ichikawa H,Yoshida N,Matsui H,Yoshikawa T

更新日期：2006-01-01 00:00:00

abstract：:D-Galactosamine administration to rats (400 mg/kg) by intraperitoneal injection induced biochemical alterations in liver plasma membranes. Alterations were studied 4, 16 and 24 h after D-galactosamine injection. Plasma membrane 5'-mononucleotidase activity decreased to 40% of control values. Carbohydrate composition w...

journal_title：Digestion

authors： Bertrand F,Veissiere D,Picard J

更新日期：1979-01-01 00:00:00

abstract：:8 children, known to have been hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) positive for more than 6 months and with chronic active hepatitis on biopsy, received 2.5 mg levamisole/kg/day, 2 days a week for 6-18 months. In 6 of the 8 children transaminases normalized within 4-18 months of thera...

journal_title：Digestion

authors： Fattovich G,Cadrobbi P,Crivellaro C,Pornaro E,Alberti A,Realdi G

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND/AIMS:L-glutamine (L-gln) is a conditionally essential amino acid which is consumed by certain tissues like the intestine in large amounts as energy source during critical illness. Apart from nutritive action, recent data suggest a link to heat-shock protein (hsp) induction. We investigated the effect of L-gl...

journal_title：Digestion

authors： Lindemann G,Grohs M,Stange EF,Fellermann K

更新日期：2001-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00

abstract：:The effects of gastric fundectomy and antrectomy on the colonic mucosa were studied in hamsters over 5 and 25 days. Sham-operated animals served as controls. Basal plasma gastrin concentrations were significantly increased after fundectomy and significantly decreased after antrectomy. Five days after fundectomy, there...

journal_title：Digestion

authors： Chu M,Rehfeld JF,Borch K

更新日期：1992-01-01 00:00:00

abstract：:The effect of feeding an alpha-amylase inhibitor (BAY e 4609, 700 mg/100 g food) for 20 or 90 days on the enzymes of the exocrine pancreas of the rat was investigated. The amylase inhibitor-fed rats gained significantly less weight despite a higher food intake than control rats on a standard diet. Fecal weight increas...

journal_title：Digestion

authors： Fölsch UR,Grieb N,Caspary WF,Creutzfeldt W

更新日期：1981-01-01 00:00:00

abstract：:The urinary excretion rates of nitrate (NO3) and nitrite (NO2) were monitored in 14 patients with active ulcerative colitis during treatment using hydrocortisone and sulfasalazine. During the active phase of the disease, the NO3 excretion was significantly higher in the patients than in healthy controls (n = 6, p < 0....

journal_title：Digestion

authors： Sasajima K,Yoshida Y,Yamakado S,Sato J,Miyashita M,Okawa K,Matsutani T,Onda M,Kawano E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Since resistance of Helicobacter pylori is developing very fast all over the world, new treatment regimens for eradication are urgently needed. AIM:To compare eradication success rate of H. pylori treatment regimens with and without doxycycline. METHODS:English medical literature searches were conducted fo...

journal_title：Digestion

authors： Niv Y

更新日期：2016-01-01 00:00:00

abstract：:The influence of CDCA and UDCA administration on human intestinal permeability to lactulose, as disclosed by intravenous CCK, has been investigated. For this purpose the fraction of lactulose excreted in the urine during 5 h after an oral load of the disaccharide in hypertonic solution was measured in 12 healthy subje...

journal_title：Digestion

authors： Budillon G,Parrilli G,Capuano G,Mazzacca G,Menzies IS

更新日期：1982-01-01 00:00:00

abstract：:We demonstrate that, in patients taking non-steroidal anti-inflammatory drugs (NSAIDs), there is inhibition of the proliferation of mucosal cells that normally leads to healing of duodenal ulcers. A microdissection technique was used to quantitate mitosis in duodenal crypts at the ulcer edge, giving a regeneration ind...

journal_title：Digestion

authors： Levi S,Goodlad RA,Lee CY,Stamp G,Walport MJ,Wright NA,Hodgson HJ

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:People may have symptoms of multiple disorders at the same time. We aimed to determine prevalence and risk factors for overlaps between gastroesophageal reflux disease (GERD), dyspepsia and irritable bowel syndrome (IBS) in a Korean population. METHODS:A cross-sectional survey was performed on 1,688 ra...

journal_title：Digestion

authors： Lee SY,Lee KJ,Kim SJ,Cho SW

更新日期：2009-01-01 00:00:00

abstract：:Cholecystokinin (CCK) is known to inhibit gastric acid secretion and gastric emptying but its physiological role in the inhibition of gastric functions is not settled. In this study performed on 16 young male subjects, gastric acid secretion and emptying rate were determined after intragastric administration of 8% pep...

journal_title：Digestion

authors： Konturek SJ,Kwiecien N,Obtulowicz W,Kopp B,Oleksy J,Rovati L

更新日期：1990-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00