Effect of secretin on intestinal monosaccharide absorption and new water movement in the rat.

Abstract:

:Repeated intravenous injections of 2.0 clinical units (CU) secretin per kg body weight showed no effect on jejunal glucose absorption and net water movement in perfusion studies in vivo. The in vitro uptake of galactose and 3-O-methylglucose was not altered by a secretin load given 12 min before sacrifice. The values for Km and Vmax were identical after secretin and in a control group. The conflicting results of different authors concerning the effect of secretin on net water movement and solute absorption may be due to differences in experimental techniques, different, mostly pharmacological doses of the hormone, and a diverse response of heterogeneous species.

journal_name

Digestion

journal_title

Digestion

authors

Böhmer R,Rommel K

doi

10.1159/000197730

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

325-33

issue

6

eissn

0012-2823

issn

1421-9867

journal_volume

13

pub_type

杂志文章
  • Polyamines and the recovery of intestinal morphology and function after ischemic damage in rats.

    abstract::We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201143

    authors: Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

    更新日期:1994-01-01 00:00:00

  • Treatment of peptic ulcer.

    abstract::The current therapy of choice for all Helicobacter pylori-associated ulcer disease is eradication therapy. Although adequate therapeutic regimens are currently available, often still ineffective therapies are tried. Cure of the infection essentially eliminates the ulcer diathesis. Cure of the infection is especially i...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000007522

    authors: Tytgat GN

    更新日期:1998-08-01 00:00:00

  • Plasmapheresis in Crohn's disease.

    abstract::6 patients with Crohn's disease for 1-14 years have been treated with plasmapheresis for periods of up to 6 months. The symptoms of the one newly diagnosed patient were controlled by plasmapheresis alone, and 5 steroid-dependent patients were able to reduce their steroid requirements. During the study period, 13 clini...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198344

    authors: Holdstock GE,Fisher JA,Hamblin TJ,Loehry C

    更新日期:1979-01-01 00:00:00

  • Can daily dietary arginine supplement affect the function and subpopulation of lymphocytes in patients with advanced gastric cancer?

    abstract::Since arginine can stimulate lymphocyte proliferation in the healthy human, its effect on lymphocyte proliferation in vitro was studied in 7 patients with far advanced gastric cancer. These patients with normal nourishment were ambulatory and could consume a regular diet. A daily dietary supplement of 30 g arginine fo...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201023

    authors: Wu CW,Chi CW,Chiu CC,Wu HS,Liu WY,P'eng FK,Wang SR

    更新日期:1993-01-01 00:00:00

  • Risk Factors for Delayed Hemorrhage after Colonic Endoscopic Mucosal Resection in Patients Not on Antithrombotic Therapy: Retrospective Analysis of 3,844 Polyps of 1,660 Patients.

    abstract:BACKGROUND/AIMS:Colonic endoscopic mucosal resection (EMR) is safe for patients without antithrombotic therapy; however, EMR is associated with several risks. This study was performed to evaluate the risk of delayed hemorrhage in patients undergoing EMR without antithrombotic therapy. METHODS:In the present retrospect...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000494455

    authors: Tsuruta S,Tominaga N,Ogata S,Tsuruoka N,Sakata Y,Shimoda R,Eguchi Y,Anzai K,Hara M,Fujimoto K

    更新日期:2019-01-01 00:00:00

  • Comparison of the therapeutic effect of wheat bran, mebeverine and placebo in patients with the irritable bowel syndrome.

    abstract::There is no generally accepted treatment in the irritable bowel syndrome (IBS), probably because of a lack of convincing therapeutic trials. In the present study, 120 outpatients with IBS participated in a prospective randomized therapeutic trial. According to a double-blind design, 40 patients received 400 mg/day meb...

    journal_title:Digestion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000199329

    authors: Kruis W,Weinzierl M,Schüssler P,Holl J

    更新日期:1986-01-01 00:00:00

  • Marked increases of plasma gamma-aminobutyric acid concentrations in cirrhotic patients with portacaval shunts are not associated with alterations of cerebral functions.

    abstract::Several previous studies have shown that the plasma concentration of gamma-amino-butyric acid (GABA) is markedly increased in patients with hepatic encephalopathy, and it has been suggested that decreased metabolism of peripheral GABA might contribute to the cerebral dysfunctions observed. In the present study, plasma...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000200724

    authors: Löscher W,Kretz FJ,Karavias T,Dillinger U

    更新日期:1991-01-01 00:00:00

  • Effect of rioprostil, a synthetic prostaglandin E1 on meal-stimulated gastric acid secretion and plasma gastrin levels in humans.

    abstract::The effects of rioprostil (a newly developed synthetic prostaglandin E1 analogue) on meal-stimulated gastric acid secretion was evaluated in 8 healthy human volunteers. Gastric acid output was measured by intragastric titration on 4 different occasions. The following procedure was invariably employed: after a basal pe...

    journal_title:Digestion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000199413

    authors: Schulte K,Singer MV,Eysselein V,Demol P,Goebell H

    更新日期:1987-01-01 00:00:00

  • Lecithin: cholesterol acyltransferase activity in patients with chronic liver diseases and positive LP-X tests.

    abstract::Lecithin: cholesterol acyltransferase activity has been measured in serum from patients with various liver disorders and positive LP-X tests and from healthy subjects. Statistical analysis indicated that lecithin: cholesterol acyltransferase activity provided no help in the discrimination between the persons of both g...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198149

    authors: Jung K,Schimmelpfennig W,Wack R,Neumann R

    更新日期:1978-01-01 00:00:00

  • Duodenal toxicity of dietary Phaseolus vulgaris lectins in the rat: an integrative assay.

    abstract::It is now generally admitted that phytohemagglutinin (PHA) constitutes the main factor responsible for the dietary toxicity of raw kidney beans. In the growing rat, an impairment of growth is the unique expression of a malnutrition syndrome. The aim of this work was to precise to what extent the intestinal injuries ma...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199736

    authors: Lafont J,Rouanet JM,Gabrion J,Assouad JL,Zambonino Infante JL,Besançon P

    更新日期:1988-01-01 00:00:00

  • Calcium secretion from the feline pancreas. Influence of hormonal and cholinergic secretagogues and of serum calcium.

    abstract::The influences of secretagogues and of elevated serum calcium concentrations on the calcium secretion from the cat pancreas have been studied in vivo. During a high and constant fluid secretion rate evoked by a background infusion of secretin, additional infusions of both cholecystokinin-pancreozymin and urecholine le...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198873

    authors: Layer P,Hotz J,Goebell H

    更新日期:1983-01-01 00:00:00

  • Human chorionic gonadotropin-beta in the differentiation of malignancy-related and nonmalignant ascites.

    abstract::The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201324

    authors: Gerbes AL,Hoermann R,Mann K,Jüngst D

    更新日期:1996-01-01 00:00:00

  • Endoscopic manometry in the diagnosis of the postcholecystectomy pain syndrome.

    abstract::A manometric study of the distal biliary tract was carried out by means of a side-hole perfused catheter passed through the papilla Vateri during duodenoscopy in patients with postcholecystectomy biliary pain not due to stones or inflammation of the biliary tree. The sphincter of Oddi showed in these cases a significa...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198979

    authors: Bortolotti M,Caletti GC,Brocchi E,Bersani G,Caletti T,Guizzardi G,Labò G

    更新日期:1983-01-01 00:00:00

  • Adenylate cyclase of human gastric mucosa. Stimulation of enzyme activity by histamine and catecholamines.

    abstract::Human gastric mucosal adenylate cyclase has been shown to be sensitive to histamine and catecholamines. Stimulation of enzyme activity by histamine and catecholamines were selectively blocked by cimetidine and propranolol, respectively. Combination of both hormones at maximally effective concentrations were additive, ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198069

    authors: Simon B,Kather H

    更新日期:1977-01-01 00:00:00

  • Effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients.

    abstract::This study was undertaken to evaluate the effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients. Sixteen cirrhotics were randomly assigned to metoclopramide (10 mg i.v.) or saline. Metoclopramide significantly decreased transmural variceal pressure (15.7% decr...

    journal_title:Digestion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000200477

    authors: Taranto D,Suozzo R,de Sio I,Romano M,Caporaso N,Del Vecchio Blanco C,Coltorti M

    更新日期:1990-01-01 00:00:00

  • Effect of gastrin on fasting and postprandial plasma GIP release in man.

    abstract::In order to evaluate the mechanism behind the augmented postprandial gastric inhibitory polypeptide (GIP) release seen in patients with achlorhydria and hypergastrinemia, 8 healthy subjects were given a liquid test meal on three different days. On 1 day the meal was preceded by ranitidine (H2 receptor antagonist) to b...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198815

    authors: Jorde R,Schulz TB,Burhol PG,Waldum HL

    更新日期:1982-01-01 00:00:00

  • Anatomic variations of the intrahepatic bile ducts: analysis of magnetic resonance cholangiopancreatography in 1011 consecutive patients.

    abstract:OBJECTIVES:The aim of the study was to evaluate the frequency of anatomic variations of the hepatic duct bifurcation using magnetic resonance cholangiopancreatography (MRCP). METHODS:A total of 1,160 consecutive patients, referred to our department for MRCP due to suspected pancreatobiliary disease or before liver tra...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000358558

    authors: Uysal F,Obuz F,Uçar A,Seçil M,Igci E,Dicle O

    更新日期:2014-01-01 00:00:00

  • Central leptin and cholecystokinin in gastroprotection against ethanol-induced damage.

    abstract:BACKGROUND:Leptin, a product of the ob gene controlling food intake, has recently been detected in the stomach and shown to be released by cholecystokinin (CCK) and to induce gastroprotection against various noxious agents, but it is not known whether centrally applied leptin influences gastric secretion and mucosal in...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007805

    authors: Brzozowski T,Konturek PC,Konturek SJ,Pierzchalski P,Bielanski W,Pajdo R,Drozdowicz D,Kwiecień S,Hahn EG

    更新日期:2000-01-01 00:00:00

  • Efficacy of Full-Spectrum Endoscopy to Visualize the Major Duodenal Papilla in Patients with Familial Adenomatous Polyposis.

    abstract:BACKGROUND AND AIMS:Duodenal cancer is one of the extracolonic malignancies with known mortality in familial adenomatous polyposis (FAP) patients. Visualization of the major duodenal papilla (MDP) with a standard esophagogastroduodenoscopy (EGD) is currently insufficient because of the limited field of view. Full-spect...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000501476

    authors: Ichijima R,Abe S,Kobayashi S,Minagawa T,Tagawa T,Nakajima T,Yamada M,Takamaru H,Sekiguchi M,Sakamoto T,Oda I,Matsuda T,Saito Y,Gotoda T

    更新日期:2020-01-01 00:00:00

  • Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats.

    abstract::The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199903

    authors: Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

    更新日期:1989-01-01 00:00:00

  • Failure of a prolyl 4-hydroxylase inhibitor to alter extracellular matrix deposition during experimental pancreatitis.

    abstract::In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201423

    authors: Weidenbach H,Lerch MM,Turi S,Bachem M,Adler G

    更新日期:1997-01-01 00:00:00

  • Clinical profiles, endoscopic and laboratory features and associated factors in patients with autoimmune gastritis.

    abstract:BACKGROUND/AIMS:Autoimmune gastritis (AIG) may predispose to gastric carcinoid tumors or adenocarcinomas and may also cause unexplained iron and/or vitamin B(12) deficiency. The aims of this study were to explore clinical manifestations, endoscopic findings and laboratory features of patients with AIG. METHODS:109 pat...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000338295

    authors: Soykan I,Yakut M,Keskin O,Bektaş M

    更新日期:2012-01-01 00:00:00

  • Constipation in patients with thiamine deficiency after Roux-en-Y gastric bypass surgery.

    abstract:BACKGROUND/AIMS:Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide. We have described thiamine deficiency in patients with small intestinal bacterial overgrowth after gastric bypass. We hypothesized that symptoms of thiamine deficiency are common after gastric bypass. The aims of this study...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000353245

    authors: Shah HN,Bal BS,Finelli FC,Koch TR

    更新日期:2013-01-01 00:00:00

  • Physiological study of pH stability and sensitivity to pepsin of human gastric lipase.

    abstract:BACKGROUND/AIMS:The aim of this study was to exactly determine the pH stability of human gastric lipase (HGL) and to investigate the mechanism underlying the inactivation of HGL which occurs in gastric juice. METHODS:Samples of human gastric juice and purified HGL were incubated at various pH values ranging from 0.5 t...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000057708

    authors: Ville E,Carrière F,Renou C,Laugier R

    更新日期:2002-01-01 00:00:00

  • Stimulation of disaccharidase activities in the jejunal brush border membrane of adult rat by total parenteral nutrition. Effects of thyroid hormones.

    abstract::This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199030

    authors: Raul F,Galluser M,Doffoel M

    更新日期:1984-01-01 00:00:00

  • EEG in ulcerative colitis.

    abstract::Electroencephalographic tracings of 50 patients with ulcerative colitis (UC) were compared with those of 75 controls. In the UC patients a 24% incidence of abnormal tracings was found as compared with an 8% incidence in the controls. A higher incidence of abnormal electroencephalograms was found among active cases of ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000197695

    authors: Eschar J,Arlazoroff A,Kleinhaus M,Mera A,Gilat T,Weissman I

    更新日期:1975-01-01 00:00:00

  • Rat small intestinal laminin-binding proteins.

    abstract::Mucosal intestinal cells migrate and differentiate simultaneously as they move out of the crypts to their functional site along the villus. Interactions between the enterocyte basal membrane domain and the extracellular intestinal basement membrane (IBM) have been suggested to be essential to both cell migration and d...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000200363

    authors: Wilson JR,Weiser MM

    更新日期:1990-01-01 00:00:00

  • Evaluation of small bowel injury in patients with rheumatoid arthritis by capsule endoscopy: effects of anti-rheumatoid arthritis drugs.

    abstract:BACKGROUND AND AIM:The medical treatment of rheumatoid arthritis (RA) includes nonsteroidal anti-inflammatory drugs (NSAIDs), low-dose corticosteroids, and disease-modifying antirheumatic drugs (DMARDs). We evaluated the incidence of small bowel injury in RA patients who were taking anti-RA drugs with or without concom...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000190403

    authors: Sugimori S,Watanabe T,Tabuchi M,Kameda N,Machida H,Okazaki H,Tanigawa T,Yamagami H,Shiba M,Watanabe K,Tominaga K,Fujiwara Y,Oshitani N,Koike T,Higuchi K,Arakawa T

    更新日期:2008-01-01 00:00:00

  • Loss of circadian rhythm in luminal acidity of canine stomach by implantation of a gastric fistula.

    abstract::One to four months after implantation of a gastric fistula, a circadian rhythm in gastric acidity could be demonstrated by use of the intragastric 24-hour pH-metry in dogs with the gastric fistula protruding on the left side of the upper abdomen. This circadian rhythm was found to be fully developed within 3 years, an...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201219

    authors: Postius S,Bräuer U

    更新日期:1995-01-01 00:00:00

  • The motor-stimulating effect of natural motilin on the lower esophageal sphincter fundus, antrum and duodenum in dogs.

    abstract::Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000197714

    authors: Jennewein HM,Hummelt H,Siewert R,Waldeck F

    更新日期:1975-01-01 00:00:00