Efficacy of Full-Spectrum Endoscopy to Visualize the Major Duodenal Papilla in Patients with Familial Adenomatous Polyposis.

abstract：:In order to study some of the molecular events during the hepatic passage of gastrin, we perfused sulfated natural porcine gastrin (G17 II) through isolated pig livers. The disappearance half time of G17 II was about 20-30 min when the starting gastrin concentrations were greater than 100 pM; lower concentrations were...

journal_title：Digestion

authors： Feurle GE,Winkler C,Encke A,Helmstaedter V,Doertenbach JG

更新日期：1984-01-01 00:00:00

abstract：:The form in which copper is bound in bile was studied in bile from patients with Wilson's disease, control subjects and rats. Bile was labelled with 64Cu. Sephadex column chromatography using gels G-200--G-10 showed a major 64Cu and protein peak of about 5,000 daltons and a minor peak of about 8,000 daltons. A high-mo...

journal_title：Digestion

authors： Frommer DJ

更新日期：1977-01-01 00:00:00

abstract：:The surface epithelial cells of the gastroduodenal mucosa are thought to be protected from the damaging effects of acid by a covering layer of mucus into which is secreted bicarbonate. It is proposed here that mucus acts as a true barrier to hydrogen ion diffusion, and that the role played by bicarbonate is to adjust ...

journal_title：Digestion

authors： Vadgama P,Alberti KG

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND/AIMS:The mitogenic signaling pathway of epidermal growth factor receptor (EGFR) is activated in a variety of cancers, including hepatocellular carcinoma (HCC). The recently cloned EGFR-related protein (ERRP) has been proposed to be a negative regulator of EGFR. The expression of ERRP in non-malignant liver c...

journal_title：Digestion

authors： Moon WS,Chang KJ,Majumdar AP,Tarnawski AS

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

journal_title：Digestion

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-11-18 00:00:00

abstract：:We studied the pancreatic secretory response to sham feeding alone or during secretin infusion with and without administration of atropine in 10 human subjects. The magnitude of the response to sham feeding was compared to the response to cholecystokinin octapeptide. Sham feeding alone did not significantly increase p...

journal_title：Digestion

authors： Defilippi C,Solomon TE,Valenzuela JE

更新日期：1982-01-01 00:00:00

abstract：:A statistical study was carried out to determine if fasting serum bile acid levels are clinically useful in differentiating children with chronic persistent hepatitis from children with chronic aggressive hepatitis. Serum bile acid levels were determined in 27 patients with chronic aggressive hepatitis, 41 with chroni...

journal_title：Digestion

authors： Jara P,Codoceo R,Hernanz A,Castaño C,Diaz C,Montero JL,Vázquez C

更新日期：1983-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:gamma delta T cell populations are well-known for their unique distribution (e.g. intra-epithelial lymphocytes). Though their ligands play a major role in the immune response they have remained largely obscure. To shed light on this issue, we have analyzed in this study the complementarity det...

journal_title：Digestion

authors： Ishiguro Y,Kanazawa H,Yamagata K,Sakuraba H,Munakata A

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:In this report, we aimed to investigate the distribution and characterization of biomarker-immunolabeled ductal epithelium in advanced pancreatic ductal adenocarcinoma (PDAC). DESIGN:Eighteen patients with PDAC were medically diagnosed prior to being treated periodically. All clinical records were coll...

journal_title：Digestion

authors： Zhou R,Xu X,Liu M,Wu X,Li R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:A trophic role of gastrin has been convincingly demonstrated in the oxyntic mucosa of the stomach, but is still a matter of debate in the lower gastrointestinal tract. METHODS:In order to examine the role of circulating gastrin in colorectal adenoma and carcinoma fasting serum gastrin concentrations we...

journal_title：Digestion

authors： Lamberts R,Wartenberg T,Creutzfeldt W

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to see whether administration of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, could prevent the development of gastric cancer via inhibition of apurinic/apyrimidinic endonuclease-1 (APE-1) expression induced by Helicobacter pylori infection. METHODS:70 Mongol...

journal_title：Digestion

authors： Futagami S,Kawagoe T,Horie A,Shindo T,Hamamoto T,Suzuki K,Kusunoki M,Miyake K,Gudis K,Tsukui T,Crowe SE,Sakamoto C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adenosine deaminase (ADA)-deficient disease, a severe combined immunodeficiency, is most commonly associated with gastrointestinal disorders such as ulcer. The present study investigated the role of ADA in the pathogenesis of gastric ulcer. METHODS:ADA activity was measured in a variety of organs and t...

journal_title：Digestion

authors： Yaguchi T,Saito M,Yasuda Y,Nishizaki T

更新日期：2010-01-01 00:00:00

abstract：:Somatostatin (SST) has been shown to induce cholestasis in the dog and in the rat. In man, it is still unknown whether SST modifies bile formation. The present study was undertaken to examine the influence of SST on bile secretion in man. Two volunteers who had a total external biliary fistula received 1-hour SST infu...

journal_title：Digestion

authors： Marteau P,Chrétien Y,Calmus Y,Parc R,Poupon R

更新日期：1989-01-01 00:00:00

abstract：:Gastrinomas may occur in the pancreas, duodenum or peripancreatic lymph nodes. The gastrin overproduction leads to the Zollinger-Ellison syndrome with multiple gastric and duodenal ulcers and diarrhea. About two thirds of gastrinomas are malignant. Diagnosis is made by clinical history, gastroscopy, and measurement of...

journal_title：Digestion

authors： Granberg D,Jacobsson H,Oberg K,Gustavsson J,Lehtihet M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Currently, a split-dose of polyethylene glycol (PEG) is the mainstay of bowel preparation due to its tolerability, bowel-cleansing action, and safety. However, bowel preparation with PEG is suboptimal because residual fluid reduces the polyp detection rate and requires a more thorough colon inspection. ...

journal_title：Digestion

authors： Kim HJ,Kim TO,Shin BC,Woo JG,Seo EH,Joo HR,Heo NY,Park J,Park SH,Yang SY,Moon YS,Shin JY,Lee NY

更新日期：2012-01-01 00:00:00

abstract：:The pancreatic exocrine secretory response to increasing doses of exogenous caerulein with and without a background infusion of secretin was studied in 5 healthy volunteers. Caerulein over a full range of doses (2.3-37 pmol/kg/h) produced increasing enzyme secretion up to 18.5 pmol/kg/h, whereas 37 pmol/kg/h was clear...

journal_title：Digestion

authors： Beglinger C,Köhler E,Stalder GA,Jansen J,Gyr K

更新日期：1986-01-01 00:00:00

abstract：:Chemiluminescence (CL) is a simple quantitative assay of polymorphonuclear leucocyte (PMNL) oxidative metabolism. PMNL CL was found to be significantly higher in patients with chronic inflammatory bowel disease than in normal controls (167 +/- 60 vs. 139 +/- 50 mV/10(5) cells, p less than 0.05). There were no signific...

journal_title：Digestion

authors： Kelleher D,Feighery C,Weir DG

更新日期：1990-01-01 00:00:00

abstract：:Serum antibodies directed against 5 alimentary antigens and antigen-antibody complexes were determined in 15 control subjects and in 15 patients with alcoholic liver cirrhosis. Cirrhotic patients presented an increased immune response against these antigens. Antigen-antibody complexes were detected in the fasting plas...

journal_title：Digestion

authors： André F,Druguet M,André C

更新日期：1978-01-01 00:00:00

abstract：:Chornic exogenous administration of cholecystokinin octapeptide (CCK8) to rats led to a reduced sensitivity of pancreatic acinar cells to both CCK8 and carbachol stimulation without changes in affinity or number of CCK or muscarinic receptors. In addition, repeated feeding of camostate, a synthetic protease inhibitor ...

journal_title：Digestion

authors： Herzig KH,May D,Louie DS,Takahashi T,Göke B,Owyang C

更新日期：1990-01-01 00:00:00

abstract：:The alpha-glucosidase inhibitor voglibose (AO-128) was designed to prevent rapid postprandial blood glucose rises in non-insulin-dependent diabetics. We analyzed its effect on the entero-insular axis in 72 healthy volunteers in a double-blind study design before, after the 1st dose, and on the 7th day of a 7-day treat...

journal_title：Digestion

authors： Göke B,Fuder H,Wieckhorst G,Theiss U,Stridde E,Littke T,Kleist P,Arnold R,Lücker PW

更新日期：1995-01-01 00:00:00

abstract：:Recent studies have demonstrated the presence of both CCKA and CCKB receptors on dog and guinea pig pancreas. Although CCKA receptors are implicated in enzymatic secretion, biological effects of CCKB receptors are still unknown. We have previously found that a rat acinar pancreatic cell line (AR4-2J) possesses both re...

journal_title：Digestion

authors： Seva C,De Vries L,Scemama JL,Sarfati P,Nicolet TG,Pradayrol L,Vaysse N

更新日期：1990-01-01 00:00:00

abstract：:Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagn...

journal_title：Digestion

authors： Okubo M,Tahara T,Shibata T,Nakamura M,Kamiya Y,Yoshioka D,Maeda Y,Yonemura J,Ishizuka T,Arisawa T,Hirata I

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma (CCA) is the most common hepatobiliary malignancy complicating primary sclerosing cholangitis (PSC). Unfortunately, timely diagnosis of CCA in PSC patients remains challenging. AIM:To investigate the strategies among liver centers regarding pre-transplant screening for CCA in patients wit...

journal_title：Digestion

authors： Trilianos P,Selaru F,Li Z,Gurakar A

更新日期：2014-01-01 00:00:00

abstract：:At 1 year after a first resection, up to 80% of patients show an endoscopic recurrence, 10-20% have clinical relapse, and 5% have surgical recurrence. Smoking is one of the most important risk factors for postoperative recurrence. Preoperative disease activity and the severity of endoscopic lesions in the neoterminal ...

journal_title：Digestion

authors： Froehlich F,Juillerat P,Felley C,Mottet C,Vader JP,Burnand B,Michetti P,Gonvers JJ

更新日期：2005-01-01 00:00:00

abstract：:The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during i...

journal_title：Digestion

authors： Laskus T,Radkowski M,Slusarczyk J,Cianciara J

更新日期：1992-01-01 00:00:00

abstract：:Mucosal intestinal cells migrate and differentiate simultaneously as they move out of the crypts to their functional site along the villus. Interactions between the enterocyte basal membrane domain and the extracellular intestinal basement membrane (IBM) have been suggested to be essential to both cell migration and d...

journal_title：Digestion

authors： Wilson JR,Weiser MM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIM:Reddish depressed lesions (RDLs) frequently observed in patients following Helicobacter pylori eradication are indistinguishable from gastric cancer. We examined the clinical and histological feature of RDLs and its relevant endoscopic diagnosis including magnifying narrow-band imaging (M-NBI). METH...

journal_title：Digestion

authors： Kotachi T,Ito M,Boda T,Kiso M,Masuda K,Hata K,Kawamura T,Sanomura Y,Yoshihara M,Tanaka S,Chayama K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:As opposed to regular C-reactive protein (CRP) assays, the introduction of high-sensitivity ones has enabled us to detect low grade inflammation in patients with inflammatory bowel disease (IBD). We addressed the subject of the degree of correlation between the concentration of high-sensitivity CRP (hs-...

journal_title：Digestion

authors： Zilberman L,Maharshak N,Arbel Y,Rogowski O,Rozenblat M,Shapira I,Berliner S,Arber N,Dotan I

更新日期：2006-01-01 00:00:00

abstract：:The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

journal_title：Digestion

authors： Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

更新日期：1989-01-01 00:00:00