Immunophenotypes of Ductal Epithelial Cells in Advanced Pancreatic Ductal Adenocarcinoma.

abstract：:Sedation and analgesia is the standard of care during diagnostic and therapeutic endoscopic gastrointestinal procedures in most areas of the world. Unsedated endoscopy is feasible in selected patients, but requires commitment on the part of both the patient and the provider. The American Society of Anesthesiologists h...

journal_title：Digestion

authors： Paspatis GA,Tribonias G,Paraskeva K

更新日期：2010-01-01 00:00:00

abstract：:The role of altered gastric motor functions for the development of obesity is still unclear. In this study, we investigated whether severe obesity is related to gastric dysfunctions or to abnormal perception in response to distension. 31 obese patients and 20 healthy volunteers were studied using an electronic barosta...

journal_title：Digestion

authors： Klatt S,Pieramico O,Güthner C,Ditschuneit HH,Glasbrenner B,Beckh K,Adler G

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:gamma delta T cell populations are well-known for their unique distribution (e.g. intra-epithelial lymphocytes). Though their ligands play a major role in the immune response they have remained largely obscure. To shed light on this issue, we have analyzed in this study the complementarity det...

journal_title：Digestion

authors： Ishiguro Y,Kanazawa H,Yamagata K,Sakuraba H,Munakata A

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) is recognized as a minimally invasive and curative treatment for superficial gastrointestinal (GI) cancers. However, ESD is still challenging and time-consuming with a high risk of adverse events such as bleeding and perforation. Various traction methods have been explo...

journal_title：Digestion

authors： Kaku H,Toyonaga T,Tanaka S,Takihara H,Baba S,Tsubouchi E,Ikeda Y,Orita H,Nakamoto M,Horikawa Y,Chiba H,Ban H,Furumoto Y,Morita R,Kodama Y

更新日期：2020-12-22 00:00:00

abstract：:Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...

journal_title：Digestion

authors： Jennewein HM,Hummelt H,Siewert R,Waldeck F

更新日期：1975-01-01 00:00:00

abstract：:Jejunal suction biopsies of 18 chronic alcoholics (alcohol intake of more than 100 g of ethanol per day for several years) and 10 nonalcoholic control subjects were analyzed quantitatively using the microdissection technique described by Clarke. Both groups were comparable concerning age, body weight and sex. The dura...

journal_title：Digestion

authors： Bode JC,Knüppel H,Schwerk W,Lorenz-Meyer H,Dürr HK

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND/AIMS:Transgenic mice overexpressing hepatitis B x protein (HBx) show an increased susceptibility to mutations if exposed to mutagens. Also involved in HBx signalling, reactive oxygen intermediates (ROI) can induce DNA adducts such as 8-hydroxy-2'-deoxyguanosine that can in turn lead to G/T transversion mutat...

journal_title：Digestion

authors： Gehrke R,Brauchle MA,Reifenberg K,Hildt E,Gruetzner U,Schmitz V,Schlicht HJ,Hofschneider PH,Caselmann WH,Rabe C

更新日期：2004-01-01 00:00:00

abstract：:The clinical relevance of cispride's stimulating effects on lower oesophageal motility was studied in 19 patients with documented (endoscopy, biopsy) grade II or III oesophagitis. Patients were treated for 8 or 16 weeks (depending essentially on whether the result was cure or failure) with 10 mg of cisapride four time...

journal_title：Digestion

authors： Lepoutre L,Van der Spek P,Vanderlinden I,Bollen J,Laukens P

更新日期：1990-01-01 00:00:00

abstract：:D-Galactosamine administration to rats (400 mg/kg) by intraperitoneal injection induced biochemical alterations in liver plasma membranes. Alterations were studied 4, 16 and 24 h after D-galactosamine injection. Plasma membrane 5'-mononucleotidase activity decreased to 40% of control values. Carbohydrate composition w...

journal_title：Digestion

authors： Bertrand F,Veissiere D,Picard J

更新日期：1979-01-01 00:00:00

abstract：:The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during i...

journal_title：Digestion

authors： Laskus T,Radkowski M,Slusarczyk J,Cianciara J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:We evaluated the diagnostic variability and reproducibility of endoscopic signs in two populations with a different pretest likelihood of celiac disease (CD). METHODS:We recruited 289 CD patients (both adults and children) in a multicenter prospective study. Group 1 (high risk) included 111 patients re...

journal_title：Digestion

authors： Pellegrino S,Furfaro F,Tortora A,Naso P,D'Agate C,Spina M,Belluardo N,Bertone A,Passanisi G,Malandrino S,Familiari L,Villanacci V,Puzzo L,Tuccari G,Sciacca A,Vieni G,Costa S,Currò G,Magazzù G,Sferlazzas C,Bassotti

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:There are limited data concerning the clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) after double-balloon endoscopy (DBE). The aim of the present study was to evaluate the long-term outcome of patients with OGIB after DBE. PATIENTS AND METHODS:Eighty-seven consecutive pa...

journal_title：Digestion

authors： Fujita M,Manabe N,Honda K,Tarumi K,Murao T,Katada S,Kimura Y,Matsumoto H,Kamada T,Shiotani A,Hata J,Haruma K

更新日期：2010-01-01 00:00:00

abstract：:The effects of two recently developed gastrin receptor antagonists, PD 136450 and L-365,260, on pentagastrin-stimulated acid secretion were investigated in rats. PD 136450 at a dose of 6 mg/kg s.c. (9.6 mumol) completely abolished acid secretion induced by pentagastrin. The inhibition of 18 mg/kg PD 136450 s.c. lasted...

journal_title：Digestion

authors： Eissele R,Koop H,Bothe-Sandfort E,Arnold R

更新日期：1992-01-01 00:00:00

abstract：:CCK-8, bombesin, secretin and urecholine added in various concentrations to the incubation medium of the dispersed pancreatic acini, obtained from rats, resulted in a dose-dependent stimulation of amylase secretion, the half-maximal response being achieved at 3 X 10(-12), 10(-10), 10(-7) and 10(-5) M, respectively. Pi...

journal_title：Digestion

authors： Jaworek J,Konturek SJ

更新日期：1987-01-01 00:00:00

abstract：:The urinary excretion rates of nitrate (NO3) and nitrite (NO2) were monitored in 14 patients with active ulcerative colitis during treatment using hydrocortisone and sulfasalazine. During the active phase of the disease, the NO3 excretion was significantly higher in the patients than in healthy controls (n = 6, p < 0....

journal_title：Digestion

authors： Sasajima K,Yoshida Y,Yamakado S,Sato J,Miyashita M,Okawa K,Matsutani T,Onda M,Kawano E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Previous research has shown that infliximab (IFX) is effective in the management of moderate to severe active ulcerative colitis (UC). Latin American studies are lacking. AIM:To evaluate the efficacy of IFX treatment (including corticosteroid withdrawal, complete mucosal healing, colectomy and hospitalizati...

journal_title：Digestion

authors： Juliao F,Marquez J,Aristizabal N,Yepes C,Zuleta J,Gisbert JP

更新日期：2013-01-01 00:00:00

abstract：:Glycoprotein and protein production of isolated pig gastric mucosal cells were determined by the incorporation of N-acetyl-[14C]D-glucosamine ([14C]GlcNAc) and [3H]L-leucine ([3H]Leu) into acid-insoluble macromolecules (AIM). In four cell fractions (F1-F4), obtained by counterflow centrifugation, specific [14C]GlcNAc ...

journal_title：Digestion

authors： Heim HK,Oestmann A,Thiele H,Sewing KF

更新日期：1989-01-01 00:00:00

abstract：:Surgery is the only potentially curative treatment for patients with carcinoid tumors. Patients with localized disease even with lymph node metastases can be resected for potential cure. Patients with distant metastatic disease have been reported to be cured by resection of all tumor. However, long-term follow-up of t...

journal_title：Digestion

authors： Norton JA

更新日期：1994-01-01 00:00:00

abstract：:Net fluid movement and mucosal 14C-erythritol clearance were measured in ligated colonic loops of the rat in vivo. The diphenolic laxatives, oxyphenisatin and bisacodyl, dose-dependently inhibited net fluid absorption or caused secretion, both increased the 14C-erythritol clearance. Pretreatment with the adenylate cyc...

journal_title：Digestion

authors： Farack UM,Nell G

更新日期：1984-01-01 00:00:00

abstract：:In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...

journal_title：Digestion

authors： Weidenbach H,Lerch MM,Turi S,Bachem M,Adler G

更新日期：1997-01-01 00:00:00

abstract：:Saliva from one parotid gland was collected under citric acid stimulation in three groups consisting of 69 control subjects and two groups consisting of 25 patients with chronic and relapsing chronic pancreatitis. Mixed saliva was collected under mechanical stimulation from 10 patients and 6 control subjects. Flow rat...

journal_title：Digestion

authors： Dürr GH,Amouric M,Bode C,Bode JC,Sarles H,Figarella C

更新日期：1982-01-01 00:00:00

abstract：:Lecithin: cholesterol acyltransferase activity has been measured in serum from patients with various liver disorders and positive LP-X tests and from healthy subjects. Statistical analysis indicated that lecithin: cholesterol acyltransferase activity provided no help in the discrimination between the persons of both g...

journal_title：Digestion

authors： Jung K,Schimmelpfennig W,Wack R,Neumann R

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND/AIM:Previous studies have reported small intestinal lesions in patients with portal hypertensive disease. However, the etiology of these lesions is not clear, as portal venous pressure was not measured in any of these studies. The aim of this study is to clarify the association between small intestinal lesio...

journal_title：Digestion

authors： Takahashi Y,Fujimori S,Narahara Y,Gudis K,Ensaka Y,Kosugi Y,Maki K,Suzuki M,Matsushita Y,Fukuda T,Kanazawa H,Sakamoto C

更新日期：2012-01-01 00:00:00

abstract：:Plasma lactate and urate concentrations, following 50 g oral fructose, were compared in 12 control subjects and 13 patients with liver disease. No serious adverse effects occurred following fructose ingestion, and in neither group did the plasma lactate concentration exceed 5.2 mmol/l. There were no significant differ...

journal_title：Digestion

authors： Douglas JG,Beckett GJ

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The cholinergic anti-inflammatory pathway (CAIP) has been proposed as a key mechanism by which the brain, through the vagus nerve (VN), modulates the immune system in the body. Recent studies of VN stimulation (VNS) in vivo systems have shown that it plays an anti-inflammatory role through CAIP. Inflammatory...

journal_title：Digestion

authors： Lei W,Duan Z

更新日期：2019-11-29 00:00:00

abstract：:Pancreatoduodenectomy (PD) may be followed by serious complications chiefly associated with exocrine pancreatic secretion. Somatostatin and its analogues are able to inhibit pancreatic secretion and thus have been advocated for the prevention of complications following pancreatic surgery. In four published multicentri...

journal_title：Digestion

authors： Gouillat C

更新日期：1999-01-01 00:00:00

abstract：:Zinc nutriture has been studies in 30 patients with Crohn's disease using plasma zinc, hair zinc, and taste acuity as indices. Significant reductions in plasma zinc concentrations and taste acuity were seen in the patient groups as compared with normal controls. Hair zinc content was also generally low with several de...

journal_title：Digestion

authors： Solomons NW,Rosenberg IH,Sandstead HH,Vo-Khactu KP

更新日期：1977-01-01 00:00:00

abstract：:Growth hormone-releasing factor (GRF) was reported to possess the growth-promoting action on the gastroduodenal mucosa that can be augmented by removal of endogenous somatostatin. Since mucosal proliferation was considered to contribute to healing of chronic gastroduodenal ulcerations, we designed the study to determi...

journal_title：Digestion

authors： Konturek SJ,Brzozowski T,Dembinski A,Warzecha Z,Konturek PK,Yanaihara N

更新日期：1988-01-01 00:00:00

abstract：:We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

journal_title：Digestion

authors： Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

更新日期：1994-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00