Abstract:
:The role of altered gastric motor functions for the development of obesity is still unclear. In this study, we investigated whether severe obesity is related to gastric dysfunctions or to abnormal perception in response to distension. 31 obese patients and 20 healthy volunteers were studied using an electronic barostat. Basal gastric tone, gastric accommodation, and perception in response to distension were not altered in obese patients. The median minimal distending pressure, reflecting the intra-abdominal pressure, was significantly elevated in obese patients, being 12 versus 7 mm Hg, respectively (p < 0.0001). We conclude that the proximal gastric motility, including perception and accommodation in response to intragastric distension, is not impaired in severe obesity. Whether disturbances of gastric reflex relaxation in response to a meal are involved in the pathogenesis of obesity remains to be established.
journal_name
Digestionjournal_title
Digestionauthors
Klatt S,Pieramico O,Güthner C,Ditschuneit HH,Glasbrenner B,Beckh K,Adler Gdoi
10.1159/000201433subject
Has Abstractpub_date
1997-01-01 00:00:00pages
115-9issue
2eissn
0012-2823issn
1421-9867journal_volume
58pub_type
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