The pepsinogens of cat gastric mucosa and the pepsins derived from them.

Abstract:

:Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity were detected. One zone did not migrate from the origin and is possibly a non-pepsinogen gastric protease. Simultaneous electrophoresis of pepsinogens and pepsins indicated that each pepsinogen gave rise to one pepsin. One zymogen gives rise to a pepsin active with the synthetic substrate acetyl-L-phenylalanyl-L-diiodotyrosine (APDT).

journal_name

Digestion

journal_title

Digestion

authors

Shaw B,Wright CL

doi

10.1159/000197919

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

142-52

issue

2

eissn

0012-2823

issn

1421-9867

journal_volume

14

pub_type

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