Abstract:
:Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity were detected. One zone did not migrate from the origin and is possibly a non-pepsinogen gastric protease. Simultaneous electrophoresis of pepsinogens and pepsins indicated that each pepsinogen gave rise to one pepsin. One zymogen gives rise to a pepsin active with the synthetic substrate acetyl-L-phenylalanyl-L-diiodotyrosine (APDT).
journal_name
Digestionjournal_title
Digestionauthors
Shaw B,Wright CLdoi
10.1159/000197919subject
Has Abstractpub_date
1976-01-01 00:00:00pages
142-52issue
2eissn
0012-2823issn
1421-9867journal_volume
14pub_type
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