Pain in the Early Phase of Pediatric Pancreatitis (PINEAPPLE Trial): Pre-Study Protocol of a Multinational Prospective Clinical Trial.

abstract：:We consider the multiple interacting factors which lead to the proliferation of human gastric enterochromaffin-like (ECL) cells, and control of this proliferation by somatostatin and its analogues. Somatostatin receptors occur in human fundic mucosa, and octreotide can be considered a useful therapeutic tool to contro...

journal_title：Digestion

authors： Delle Fave G,Annibale B

更新日期：1996-01-01 00:00:00

abstract：:The elimination kinetics of antipyrine have been established under basal environmental conditions in 6 healthy volunteers. Concentrations of antipyrine in serum were measured by a relatively fast high-pressure liquid chromatography method using a radial-compression chromatographic system. Pretreatment of the subjects ...

journal_title：Digestion

authors： Paxton JW,Foote SE,Paton DM

更新日期：1983-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is a continuous diseases spectrum associated with obesity, type 2 diabetes, insulin resistance, and hyperlipidemia. Simple hepatic steatosis may progress to nonalcoholic steatohepatitis (NASH), even fibrosis and cirrhosis, and finally hepatocellular carcinoma. In rece...

journal_title：Digestion

authors： Zhong F,Zhou X,Xu J,Gao L

更新日期：2020-01-01 00:00:00

abstract：:Retractile mesenteritis is an extremely rare disease characterised by a non-specific inflammatory and fibrotic process of the mesenteric adipose tissue, which is usually accompanied by pain and a variety of other abdominal symptoms. We describe here the case of a patient with retractile mesenteritis presenting with pr...

journal_title：Digestion

authors： Papadaki HA,Kouroumalis EA,Stefanaki K,Roussomoustakaki M,Daskalogiannaki ME,Reppa D,Eliopoulos GD

更新日期：2000-01-01 00:00:00

abstract：:Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional cytokine which modifies tissue stromal matrix synthesis, cell proliferation and immune function. In the present study, we have used a mouse monoclonal antibody to the latent (intracytoplasmic) form of TGF-beta 1 to compare its expression in 144 cases ...

journal_title：Digestion

authors： Slater SD,Williamson RC,Foster CS

更新日期：1995-01-01 00:00:00

abstract：:23 cirrhotics with ascites and sodium retention, whose aldosteronemia had been evaluated after an equilibration period at controlled sodium intake at the occasion of previous studies, were retrospectively investigated. The dosage of spironolactone needed to induce a negative sodium balance correlated significantly wit...

journal_title：Digestion

authors： Bernardi M,Servadei D,Trevisani F,Rusticali AG,Gasbarrini G

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The cholinergic anti-inflammatory pathway (CAIP) has been proposed as a key mechanism by which the brain, through the vagus nerve (VN), modulates the immune system in the body. Recent studies of VN stimulation (VNS) in vivo systems have shown that it plays an anti-inflammatory role through CAIP. Inflammatory...

journal_title：Digestion

authors： Lei W,Duan Z

更新日期：2019-11-29 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：:Administration of cholic acid (1.0% of the diet) to male Fisher rats for 3 days resulted in increased numbers of DNA synthesizing epithelial cells per colonic crypt column as compared to those found in either control or 0.2% cholic acid-fed rats. The middle third of the crypt was the area stimulated to contribute the ...

journal_title：Digestion

authors： Deschner EE,Cohen BI,Raicht RF

更新日期：1981-01-01 00:00:00

abstract：:Chornic exogenous administration of cholecystokinin octapeptide (CCK8) to rats led to a reduced sensitivity of pancreatic acinar cells to both CCK8 and carbachol stimulation without changes in affinity or number of CCK or muscarinic receptors. In addition, repeated feeding of camostate, a synthetic protease inhibitor ...

journal_title：Digestion

authors： Herzig KH,May D,Louie DS,Takahashi T,Göke B,Owyang C

更新日期：1990-01-01 00:00:00

abstract：:Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...

journal_title：Digestion

authors： Panda AP,Laughton JM,Elder JB,Gillespie IE

更新日期：1975-01-01 00:00:00

abstract：:Mechanisms of antisecretory action of intragastric FPL-52694, a mast cell stabilizer, were investigated in anesthetized rats. In Schild's rat preparation, intravenous FPL-52694 (10 mg/kg) significantly suppressed acid secretion in response to only tetragastrin (20 micrograms/kg, i.v.) (42.1 +/- 19.4%), while intragast...

journal_title：Digestion

authors： Takeuchi K,Ueki S,Okabe S

更新日期：1986-01-01 00:00:00

abstract：:The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alp...

journal_title：Digestion

authors： Skov Olsen P,Kirkegaard P,Rasmussen T,Magid E,Poulsen SS,Nexø E

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:The incidence of early-onset inflammatory bowel disease is increasing in Japan. OBJECTIVE:This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease. METHODS:This prospective survey evaluated the data of 43 patients aged <8 years who were diagnosed with inflammatory ...

journal_title：Digestion

authors： Kudo T,Fujii T,Maisawa SI,Sasaki M,Uchida K,Ida S,Kagimoto S,Yoden A,Shimizu T

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND/AIMS:Multiple colorectal polyps with a diameter in the range of 10-19 mm are unable to be retrieved through a 3-mm endoscopic channel by the aspiration method. This study aims to assess the usefulness of Catcher Tag retrieval, which not only allows the accurate identification of the resected location but als...

journal_title：Digestion

authors： Mori H,Kobara H,Kobayashi N,Nishiyama N,Kobayashi S,Yagi T,Masaki T

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Fecal lactoferrin has been introduced as a useful tool for the diagnosis and monitoring of inflammatory bowel disease (IBD). The aim of this study was to assess if fecal lactoferrin can be employed to predict or estimate the effect of granulocyte and monocyte adsorptive apheresis (GMA) in ulcerative colitis ...

journal_title：Digestion

authors： Hashiguchi K,Takeshima F,Akazawa Y,Matsushima K,Minami H,Machida H,Yamaguchi N,Shiozawa K,Ohba K,Ohnita K,Ichikawa T,Isomoto H,Nakao K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adenosine deaminase (ADA)-deficient disease, a severe combined immunodeficiency, is most commonly associated with gastrointestinal disorders such as ulcer. The present study investigated the role of ADA in the pathogenesis of gastric ulcer. METHODS:ADA activity was measured in a variety of organs and t...

journal_title：Digestion

authors： Yaguchi T,Saito M,Yasuda Y,Nishizaki T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIM:Studies have demonstrated an important role for endogenous PG and NO in the healing of chronic gastric ulcers. We investigated the effects of COX and NOS inhibitors on the healing of duodenal ulcers, in comparison with gastric ulcers, in rats. METHODS:Gastric and duodenal ulcers were induced by serosal ...

journal_title：Digestion

authors： Araki H,Komoike Y,Matsumoto M,Tanaka A,Takeuchi K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:There are limited data concerning the clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) after double-balloon endoscopy (DBE). The aim of the present study was to evaluate the long-term outcome of patients with OGIB after DBE. PATIENTS AND METHODS:Eighty-seven consecutive pa...

journal_title：Digestion

authors： Fujita M,Manabe N,Honda K,Tarumi K,Murao T,Katada S,Kimura Y,Matsumoto H,Kamada T,Shiotani A,Hata J,Haruma K

更新日期：2010-01-01 00:00:00

abstract：:We describe a patient with relapses of Clostridium difficile cytotoxin-positive pseudomembranous colitis (PMC) after treatment with vancomycin, a course of metronidazole and a trial of bacitracin. She remains free of disease after a prolonged course of cholestyramine. We suggest there may be a role for anion-exchange ...

journal_title：Digestion

authors： Kunimoto D,Thomson AB

更新日期：1986-01-01 00:00:00

abstract：:Synthetic glucocorticoids, such as dexamethasone, and diets enriched with unsaturated fatty acids have been shown to stimulate hepatic bile salt synthesis. This fact led us to investigate the effects of dexamethasone and linoleic acid supplementation on bile secretion. Cholesterol (Ch) and phospholipid secretions are ...

journal_title：Digestion

authors： Domingo N,Debono E,Reynier MO,Crotte C,Thorin B,Charbonnier M,Clerc T,Grillasca J,Chanussot F,Lafont H

更新日期：1999-11-01 00:00:00

abstract：:The intestinal phase of enterohepatic circulation, such as site and state of bile acid absorption, along the length of the intestinal tract has been speculated but not directly quantitated. In order to gain insight into the actual state of intestinal absorption of bile acid, the bile acid composition of portal blood f...

journal_title：Digestion

authors： Fujii T,Yanagisawa J,Nakayama F

更新日期：1988-01-01 00:00:00

abstract：:The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...

journal_title：Digestion

authors： Pezzilli R,Billi P,Platè L,Bongiovanni F,Morselli Labate AM,Miglioli M

更新日期：1994-01-01 00:00:00

abstract：:A manometric study of the distal biliary tract was carried out by means of a side-hole perfused catheter passed through the papilla Vateri during duodenoscopy in patients with postcholecystectomy biliary pain not due to stones or inflammation of the biliary tree. The sphincter of Oddi showed in these cases a significa...

journal_title：Digestion

authors： Bortolotti M,Caletti GC,Brocchi E,Bersani G,Caletti T,Guizzardi G,Labò G

更新日期：1983-01-01 00:00:00

abstract：:6 patients with Crohn's disease for 1-14 years have been treated with plasmapheresis for periods of up to 6 months. The symptoms of the one newly diagnosed patient were controlled by plasmapheresis alone, and 5 steroid-dependent patients were able to reduce their steroid requirements. During the study period, 13 clini...

journal_title：Digestion

authors： Holdstock GE,Fisher JA,Hamblin TJ,Loehry C

更新日期：1979-01-01 00:00:00

abstract：:Mucosal intestinal cells migrate and differentiate simultaneously as they move out of the crypts to their functional site along the villus. Interactions between the enterocyte basal membrane domain and the extracellular intestinal basement membrane (IBM) have been suggested to be essential to both cell migration and d...

journal_title：Digestion

authors： Wilson JR,Weiser MM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Symptoms caused by chronic pancreatitis (CP) are common but often elusive hampering therapeutic decisions. Though correlations of morphologic findings in imaging and clinical appearance remain vague. We aimed in investigating whether a distinct combination of clinical parameters can better define the extent ...

journal_title：Digestion

authors： Perkhofer L,Besold T,Schmidberger J,Seufferlein T,Hann A,Müller M,Kleger A

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND/AIM:What naturally happens to patients after they undergo conservative and endoscopic treatment of colonic diverticular bleeding (CDB) is largely unknown. We retrospectively track the long-term outcome of the recurrence of CDB between patients with endoscopic and conservative treatment. METHODS:The group wa...

journal_title：Digestion

authors： Mizuki A,Tatemichi M,Nakazawa A,Tsukada N,Nagata H,Kanai T

更新日期：2016-01-01 00:00:00

abstract：:A 65-year-old woman underwent resection of a distal common bile duct carcinoma (Whipple's procedure). Twelve months later a single hepatic metastasis was detected and a chemoembolization was performed. Immediately after chemoembolization the patient developed a multimicrobial sepsis including Clostridium perfringens. ...

journal_title：Digestion

authors： Eckel F,Lersch C,Huber W,Weiss W,Berger H,Schulte-Frohlinde E

更新日期：2000-01-01 00:00:00