Rodent Models of Nonalcoholic Fatty Liver Disease.

abstract：BACKGROUND:Neoadjuvant chemotherapy for advanced gastric cancer is expected to improve prognoses. However, as there is no method to evaluate neoadjuvant chemotherapeutic efficacy before gastrectomy, some patients at high risk for a poor prognosis undergo gastrectomy. The aim of the present study was to investigate whet...

journal_title：Digestion

authors： Sugawara N,Ota K,Terazawa T,Tanaka R,Akutagawa H,Yamaguchi T,Imai Y,Harada S,Kojima Y,Tashiro K,Kii T,Lee SW,Kawai M,Egashira Y,Goto M,Uchiyama K,Hirose Y,Takeuchi T,Higuchi K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:There are unexpectedly large differences between the incidences of acute pancreatitis (AP) as indicated by different hospitals. Retrospective studies suggest that the reason behind this is the large differences that exist between the local managements of abdominal pain at emergency units. Unfortunately, no e...

journal_title：Digestion

authors： Zsoldos F,Párniczky A,Mosztbacher D,Tóth A,Lásztity N,Hegyi P,Hungarian Pancreatic Study Group and the International Association of Pancreatology.

更新日期：2016-01-01 00:00:00

abstract：:We have previously shown a specific significant overexpression in the exocrine pancreatic tissue of two members of the regenerating gene multifamily: reg I and reg II in the non-obese diabetic (NOD) mouse during active diabetogenesis. To strengthen the hypothesis that the overexpression of these genes may represent a ...

journal_title：Digestion

authors： Baeza N,Sanchez D,Christa L,Guy-Crotte O,Vialettes B,Figarella C

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

journal_title：Digestion

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) results from an aberrant immune response to the indigenous intestinal flora in genetically susceptible hosts. Therefore, the study of candidate genes involved in host pathogen interactions is of key interest. METHODS:In this two-center, retrospective German and Hungarian coh...

journal_title：Digestion

authors： Baumgart DC,Buning C,Geerdts L,Schmidt HH,Genschel J,Fiedler T,Gentz E,Molnar T,Nagy F,Lonovics J,Lochs H,Wiedenmann B,Nickel R,Witt H,Dignass A

更新日期：2007-01-01 00:00:00

abstract：:The activity of platelet-activating factor (PAF) acetylhydrolase in biopsy specimens of intestinal mucosa was compared in patients with Crohn's disease (n = 11) and controls (n = 6). In addition, PAF acetylhydrolase activity was determined in the plasma of Crohn patients (n = 30) and healthy subjects (n = 35). The act...

journal_title：Digestion

authors： Kald B,Smedh K,Olaison G,Sjödahl R,Tagesson C

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND/AIMS:Evaluation of the response of gastroesophageal reflux disease (GERD) symptoms to treatment would be facilitated by a brief, valid, reliable and responsive, self-assessed GERD-sensitive scale. We therefore developed the Reflux Questionnaire (ReQuest). This publication describes the psychometric evaluatio...

journal_title：Digestion

authors： Mönnikes H,Bardhan KD,Stanghellini V,Berghöfer P,Bethke TD,Armstrong D

更新日期：2004-01-01 00:00:00

abstract：:Different materials dissolved in 0.9% NaCl were injected into the connective, interlobular tissue of the duodenal part of the rat pancreas. Activated rat pancreatic juice or trypsin were able to induce localized necrohemorrhagic pancreatitis. Only mild edema and leukocytic infiltration were observed after injecting bo...

journal_title：Digestion

authors： Odaira C,Berger Z,Iovanna JL,Sarles H

更新日期：1986-01-01 00:00:00

abstract：:2 cases of pancreatic disease in patients with malabsorption following small bowel radiation injury are reported. It is suggested that the pancreatic disease present in these patients occurred as a result of previous radiotherapy. ...

journal_title：Digestion

authors： Mitchell CJ,Simpson FG,Davison AM,Losowsky MS

更新日期：1979-01-01 00:00:00

abstract：AIM:Although pectin, a dietary fibre, has been suggested to possess some trophic effects on the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the effects of pectin on rat intestinal cell proliferation and the intraluminal environment. METHODS:Control and pectin-fed rats were given a f...

journal_title：Digestion

authors： Fukunaga T,Sasaki M,Araki Y,Okamoto T,Yasuoka T,Tsujikawa T,Fujiyama Y,Bamba T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:L-glutamine (L-gln) is a conditionally essential amino acid which is consumed by certain tissues like the intestine in large amounts as energy source during critical illness. Apart from nutritive action, recent data suggest a link to heat-shock protein (hsp) induction. We investigated the effect of L-gl...

journal_title：Digestion

authors： Lindemann G,Grohs M,Stange EF,Fellermann K

更新日期：2001-01-01 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00

abstract：:Mechanisms of antisecretory action of intragastric FPL-52694, a mast cell stabilizer, were investigated in anesthetized rats. In Schild's rat preparation, intravenous FPL-52694 (10 mg/kg) significantly suppressed acid secretion in response to only tetragastrin (20 micrograms/kg, i.v.) (42.1 +/- 19.4%), while intragast...

journal_title：Digestion

authors： Takeuchi K,Ueki S,Okabe S

更新日期：1986-01-01 00:00:00

abstract：:The distribution of tryptophan hydroxylase, the rate-limiting enzyme in the biosynthesis of serotonin, was investigated immunohistochemically in various organs of the gastrointestinal tract and compared with that of neuroendocrine markers. While immunoreactivity for serotonin and chromogranin A was restricted to enter...

journal_title：Digestion

authors： Meyer T,Brinck U

更新日期：1999-01-01 00:00:00

abstract：:Glycoprotein and protein production of isolated pig gastric mucosal cells were determined by the incorporation of N-acetyl-[14C]D-glucosamine ([14C]GlcNAc) and [3H]L-leucine ([3H]Leu) into acid-insoluble macromolecules (AIM). In four cell fractions (F1-F4), obtained by counterflow centrifugation, specific [14C]GlcNAc ...

journal_title：Digestion

authors： Heim HK,Oestmann A,Thiele H,Sewing KF

更新日期：1989-01-01 00:00:00

abstract：:A young woman with long-standing inflammatory bowel disease presented with a tender left gastrocnemius myositis in association with an exacerbation of her disease. Muscle biopsy showed a chronic inflammatory cell infiltrate and atrophic muscle fibres, but no granulomata or vasculitis, and her symptoms responded to hig...

journal_title：Digestion

authors： Hall MJ,Thomas WE,Cooper BT

更新日期：1985-01-01 00:00:00

abstract：:The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinom...

journal_title：Digestion

authors： Lehmann FG,Kornacher J

更新日期：1975-01-01 00:00:00

abstract：:A 65-year-old woman underwent resection of a distal common bile duct carcinoma (Whipple's procedure). Twelve months later a single hepatic metastasis was detected and a chemoembolization was performed. Immediately after chemoembolization the patient developed a multimicrobial sepsis including Clostridium perfringens. ...

journal_title：Digestion

authors： Eckel F,Lersch C,Huber W,Weiss W,Berger H,Schulte-Frohlinde E

更新日期：2000-01-01 00:00:00

abstract：:Repeated intravenous injections of 2.0 clinical units (CU) secretin per kg body weight showed no effect on jejunal glucose absorption and net water movement in perfusion studies in vivo. The in vitro uptake of galactose and 3-O-methylglucose was not altered by a secretin load given 12 min before sacrifice. The values ...

journal_title：Digestion

authors： Böhmer R,Rommel K

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has been recognised as an important investigational tool in the diagnosis of gastrointestinal disease. Studies have shown that CE can identify lesions in the upper gastrointestinal tract as well as in the small intestine. However, contrary to conventional oesophagogastroscopy ...

journal_title：Digestion

authors： Peter S,Heuss LT,Beglinger C,Degen L

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Gut microbiota affects host homeostasis and dysbiosis causes host diseases. Therefore, uncovering the sensing mechanism of bacterial metabolites such as short-chain fatty acid (SCFA) may help us to understand the host-microbiota interaction both in physiological and nonphysiological conditions. SUMMARY:The ...

journal_title：Digestion

authors： Kaji I,Karaki S,Kuwahara A

更新日期：2014-01-01 00:00:00

abstract：:Chemiluminescence (CL) is a simple quantitative assay of polymorphonuclear leucocyte (PMNL) oxidative metabolism. PMNL CL was found to be significantly higher in patients with chronic inflammatory bowel disease than in normal controls (167 +/- 60 vs. 139 +/- 50 mV/10(5) cells, p less than 0.05). There were no signific...

journal_title：Digestion

authors： Kelleher D,Feighery C,Weir DG

更新日期：1990-01-01 00:00:00

abstract：:From questioning 16,939 South African pupils of 16-18 years, in 56 high schools, mean prevalences of appendicectomies in representative segments of ethnic groups were found to be: rural Blacks 0.6%; urban Blacks 0.7%; Indians, 2.9%; Coloureds (Eur-African-Malay), 1.7%; Whites, 10.5%. Percentages in the sexes were simi...

journal_title：Digestion

authors： Walker AR,Walker BF,Duvenhage A,Jones J,Ncongwane J,Segal I

更新日期：1982-01-01 00:00:00

abstract：:A case of sporadic, histamine-producing gastric carcinoid with liver metastases is reported. The patient was treated with somatostatin analogue (octreotide) combined with cortisone and blockade of histamine receptors prior to surgery, which included subtotal gastrectomy, excision of lymph node metastases and superfici...

journal_title：Digestion

authors： Kölby L,Wängberg B,Ahlman H,Jansson S,Forssell-Aronsson E,Erickson JD,Nilsson O

更新日期：1998-01-01 00:00:00

abstract：:Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

journal_title：Digestion

authors： Okabe S,Tabata K

更新日期：1981-01-01 00:00:00

abstract：:Life-long administration (greater than or equal to 2 years) of a number of long-acting gastric acid inhibitors (including H2-receptor antagonists, omeprazole and ciprofibrate) has been associated with the development of gastric enterochromaffin-like cell (ECL cell) carcinoids in rats. It has been postulated that they ...

journal_title：Digestion

authors： Carlsson E,Havu N,Mattsson H,Ekman L

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIMS:There are limited data concerning the clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) after double-balloon endoscopy (DBE). The aim of the present study was to evaluate the long-term outcome of patients with OGIB after DBE. PATIENTS AND METHODS:Eighty-seven consecutive pa...

journal_title：Digestion

authors： Fujita M,Manabe N,Honda K,Tarumi K,Murao T,Katada S,Kimura Y,Matsumoto H,Kamada T,Shiotani A,Hata J,Haruma K

更新日期：2010-01-01 00:00:00

abstract：:The effect of intercurrent diarrhoea on relapse of ulcerative colitis was investigated. Diarrhoea resulting from travel abroad, gastroenteritis or antibiotic usage resulted in an approximately 50% relapse rate. With regard to colonoscopy and barium enema, only the latter was followed by relapse and this may reflect di...

journal_title：Digestion

authors： Isgar B,Harman M,Whorwell PJ

更新日期：1983-01-01 00:00:00

abstract：:Saliva from one parotid gland was collected under citric acid stimulation in three groups consisting of 69 control subjects and two groups consisting of 25 patients with chronic and relapsing chronic pancreatitis. Mixed saliva was collected under mechanical stimulation from 10 patients and 6 control subjects. Flow rat...

journal_title：Digestion

authors： Dürr GH,Amouric M,Bode C,Bode JC,Sarles H,Figarella C

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:Few prospective population-based studies have been carried out on the incidence of inflammatory bowel disease (IBD). In a population-based study of pediatric IBD in southeastern Norway, patients <16 years at the time of diagnosis were followed up prospectively. The study reports on changes in diagnosis and c...

journal_title：Digestion

authors： Størdal K,Jahnsen J,Bentsen BS,Moum B

更新日期：2004-01-01 00:00:00