Abstract:
:A 65-year-old woman underwent resection of a distal common bile duct carcinoma (Whipple's procedure). Twelve months later a single hepatic metastasis was detected and a chemoembolization was performed. Immediately after chemoembolization the patient developed a multimicrobial sepsis including Clostridium perfringens. CT scans depicted pathognomonic signs of gas-containing abscess in the necrotic liver metastasis. She was subsequently treated with broad-spectrum antibiotics, abscess drainage and hyperbaric oxygen therapy. We conclude that antibiotic prophylaxis is recommendable for chemoembolization of liver metastasis in patients with risk factors like intestinal biliary reflux (bilioenteric anastomosis or papillotomy and biliary stenting) and bile duct cancer, otherwise severe sepsis including clostridium bacteremia may occur.
journal_name
Digestionjournal_title
Digestionauthors
Eckel F,Lersch C,Huber W,Weiss W,Berger H,Schulte-Frohlinde Edoi
10.1159/000007815subject
Has Abstractpub_date
2000-01-01 00:00:00pages
208-12issue
2-3eissn
0012-2823issn
1421-9867pii
7815journal_volume
62pub_type
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