Platelet-activating factor acetylhydrolase activity in intestinal mucosa and plasma of patients with Crohn's disease.

abstract：:Jejunal suction biopsies of 18 chronic alcoholics (alcohol intake of more than 100 g of ethanol per day for several years) and 10 nonalcoholic control subjects were analyzed quantitatively using the microdissection technique described by Clarke. Both groups were comparable concerning age, body weight and sex. The dura...

journal_title：Digestion

authors： Bode JC,Knüppel H,Schwerk W,Lorenz-Meyer H,Dürr HK

更新日期：1982-01-01 00:00:00

abstract：:The form in which copper is bound in bile was studied in bile from patients with Wilson's disease, control subjects and rats. Bile was labelled with 64Cu. Sephadex column chromatography using gels G-200--G-10 showed a major 64Cu and protein peak of about 5,000 daltons and a minor peak of about 8,000 daltons. A high-mo...

journal_title：Digestion

authors： Frommer DJ

更新日期：1977-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:There are unexpectedly large differences between the incidences of acute pancreatitis (AP) as indicated by different hospitals. Retrospective studies suggest that the reason behind this is the large differences that exist between the local managements of abdominal pain at emergency units. Unfortunately, no e...

journal_title：Digestion

authors： Zsoldos F,Párniczky A,Mosztbacher D,Tóth A,Lásztity N,Hegyi P,Hungarian Pancreatic Study Group and the International Association of Pancreatology.

更新日期：2016-01-01 00:00:00

abstract：:The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alp...

journal_title：Digestion

authors： Skov Olsen P,Kirkegaard P,Rasmussen T,Magid E,Poulsen SS,Nexø E

更新日期：1988-01-01 00:00:00

abstract：:Fasting reduced the weight, protein, DNA, RNA and polyamine contents of the small intestine of rats, but its effects on the in vivo uptake of intraperitoneally injected 14C-spermidine through the basolateral membrane of the small intestine were small. The uptake of putrescine was nearly doubled by fasting for 48 h. Fa...

journal_title：Digestion

authors： Bardócz S,Grant G,Brown DS,Ewen SW,Stewart JC,Pusztai A

更新日期：1991-01-01 00:00:00

abstract：:We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

journal_title：Digestion

authors： Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

更新日期：1994-01-01 00:00:00

abstract：:High-fidelity simulation uses simulators that combine all of the physiological and pharmacological responses of a human in a manikin. These simulators change and respond to the users and trainees. Using simulators for teaching sedation in the field of gastroenterology unifies all the advantages of manikins. To underst...

journal_title：Digestion

authors： Hofmann N,Datz C,Schöchl H

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:At present, benefits of surgical resection and appropriate selection criteria in patients affected by both hepatic and pulmonary metastases of colorectal cancer (CRC) are under discussion. Our analysis focused on a surgical series of such patients and our final aim consisted in identifying potential pro...

journal_title：Digestion

authors： Zizzo M,Galeone C,Braglia L,Ugoletti L,Siciliani A,Nachira D,Margaritora S,Pedrazzoli C,Paci M,Lococo F

更新日期：2020-01-01 00:00:00

abstract：:94 patients with peptic ulcerations of duodenum, stomach, and esophagus, who did not respond to 3 or more months high-dose (450 or 600 mg) treatment with ranitidine, were treated orally with 40 mg omeprazole daily. After healing all patients were offered long-term maintenance therapy with the same dose for 5 years. In...

journal_title：Digestion

authors： Brunner G,Creutzfeldt W,Harke U,Lamberts R

更新日期：1988-01-01 00:00:00

abstract：:Recently our studies have demonstrated that the central nervous system regulates in part mucosal cell growth and apoptosis in the rat small intestine. Ornithine decarboxylase (ODC) activity is a key enzyme for polyamine synthesis which plays an important role for the intestinal mucosal growth. We have demonstrated tha...

journal_title：Digestion

authors： Fujimoto K,Iwakiri R,Utsumi H,Kojima M,Ishibashi S,Wu B,Sakata H,Noda T

更新日期：2001-01-01 00:00:00

abstract：:108 adult patients and 34 children with chronic active hepatitis (CAH) are divided in four groups on the basis of presence and absence of hepatitis B surface antigen (HBsAg) and autoantibodies (AutoAb). There are significant differences in the numeric distribution among the four groups and the sex distribution between...

journal_title：Digestion

authors： Freudenberg J,Baumann H,Arnold W,Berger J,Büschenfelde KH

更新日期：1977-01-01 00:00:00

abstract：INTRODUCTION:Weakly acidic reflux has been reported to be the major cause of symptoms in patients with proton pump inhibitor (PPI)-refractory nonerosive reflux disease (NERD) undergoing PPI treatment. We previously reported that reflux at pH 4-5 was the main factor that induced symptoms in such patients. The present st...

journal_title：Digestion

authors： Abe Y,Koike T,Saito M,Okata T,Nakagawa K,Hatta W,Asanuma K,Uno K,Asano N,Imatani A,Masamune A

更新日期：2020-02-14 00:00:00

abstract：BACKGROUND/AIMS:The pathogenesis of dyspeptic/reflux symptoms and the clinico-pathologic profile of affected patients are still poorly understood. To improve our knowledge in this field we carried out a systematic, comparative analysis of symptom profiles and histopathologic patterns of oesophagogastroduodenal mucosa i...

journal_title：Digestion

authors： Villani L,Trespi E,Fiocca R,Broglia F,Colla C,Luinetti O,Tinelli C,Solcia E

更新日期：1998-01-01 00:00:00

abstract：:N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine HCl (DPPE) is an antihistamine with a unique profile of activity in the stomach. It is antisecretory and blocks the formation of experimental cold/stress- and ethanol-induced gastric lesions, as well as cysteamine-induced duodenal ulcers in a fashion more potent than o...

journal_title：Digestion

authors： Glavin GB,Gerrard JM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:While probiotic bacteria are successfully used in the treatment of ulcerative colitis, the effect of commercially available probiotic products is still controversial. Here, we study whether the number of living probiotic bacteria in yoghurts is altered by an interruption of the cold chain. METHODS:Thre...

journal_title：Digestion

authors： Scharl M,Geisel S,Vavricka SR,Rogler G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Bile duct stones (BDS) are usually removed via endoscopic retrograde cholangiopancreatography (ERCP) or, if ERCP remains unsuccessful, percutaneous transhepatic cholangiodrainage (PTCD). However, PTCD provides limited access to large BDSs. We analyzed a modified approach of PTCD for percutaneous therapy of B...

journal_title：Digestion

authors： Hollenbach M,Feisthammel J,Mössner J,Hoffmeister A

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has been recognised as an important investigational tool in the diagnosis of gastrointestinal disease. Studies have shown that CE can identify lesions in the upper gastrointestinal tract as well as in the small intestine. However, contrary to conventional oesophagogastroscopy ...

journal_title：Digestion

authors： Peter S,Heuss LT,Beglinger C,Degen L

更新日期：2005-01-01 00:00:00

abstract：:The luminal mucus layer of the rat's small intestine was separated from the mucosa by filling the lumen with agar jelly. When the rats were fasted overnight and given 59Fe or 65Zn by stomach tube the mucus isolated by this technique contained more isotope and more sialic acid than fed controls, and more of the isotope...

journal_title：Digestion

authors： Quarterman J

更新日期：1987-01-01 00:00:00

abstract：AIM:Although pectin, a dietary fibre, has been suggested to possess some trophic effects on the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the effects of pectin on rat intestinal cell proliferation and the intraluminal environment. METHODS:Control and pectin-fed rats were given a f...

journal_title：Digestion

authors： Fukunaga T,Sasaki M,Araki Y,Okamoto T,Yasuoka T,Tsujikawa T,Fujiyama Y,Bamba T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Supramaximal concentrations of cholecystokinin (CCK) or cerulein induce the intracellular activation of trypsinogen and the transcription factor NF-kappaB, a key regulator of inflammatory gene expression. Both events occur early in the development of an acute pancreatitis. The aim of this study was ...

journal_title：Digestion

authors： Tando Y,Algül H,Schneider G,Weber CK,Weidenbach H,Adler G,Schmid RM

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND/AIMS:Polyamine uptake from the circulation plays an important role in the maintenance of the intracellular polyamine content during extensive proliferation in intestinal mucosal cells. METHODS:Isolated basolateral membrane vesicles of the rabbit enterocyte were used to characterize polyamine transport acros...

journal_title：Digestion

authors： Milovic V,Caspary WF,Stein J

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Many studies have recently been published on acute pancreatitis; however, few large-sample studies have been focused on the risk factors for deaths in severe acute pancreatitis. To address this issue, the present study was intended to assess etiology, severity, and mortality of acute pancreatitis in the...

journal_title：Digestion

authors： Bai Y,Jia L,Wang B,Yang B,Wang L,Shi X,Zhang W,Liu Y,Zou D,Li Z

更新日期：2007-01-01 00:00:00

abstract：:Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...

journal_title：Digestion

authors： Jennewein HM,Hummelt H,Siewert R,Waldeck F

更新日期：1975-01-01 00:00:00

abstract：:The effects of gastric fundectomy and antrectomy on the colonic mucosa were studied in hamsters over 5 and 25 days. Sham-operated animals served as controls. Basal plasma gastrin concentrations were significantly increased after fundectomy and significantly decreased after antrectomy. Five days after fundectomy, there...

journal_title：Digestion

authors： Chu M,Rehfeld JF,Borch K

更新日期：1992-01-01 00:00:00

abstract：:Cholecystokinin (CCK) is known to inhibit gastric acid secretion and gastric emptying but its physiological role in the inhibition of gastric functions is not settled. In this study performed on 16 young male subjects, gastric acid secretion and emptying rate were determined after intragastric administration of 8% pep...

journal_title：Digestion

authors： Konturek SJ,Kwiecien N,Obtulowicz W,Kopp B,Oleksy J,Rovati L

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Despite the high prevalence of obstructive sleep apnea syndrome (OSAS), most individuals are unaware of its diagnosis. We assessed whether an upper gastrointestinal (GI) endoscopy can accurately predict the incidence of OSAS. METHODS:After endoscopic evaluation of laryngo-pharyngeal collapse, a total o...

journal_title：Digestion

authors： Ohata K,Sakai E,Nakao T,Kimoto Y,Ishii R,Konishi T,Ueno S,Takita M,Negishi R,Morinushi T,Muramoto T,Matsuhashi N,Nakaya T,Koba I,Nakaji S

更新日期：2019-01-01 00:00:00

abstract：AIMS:We investigated the effect of n-3 polyunsaturated fatty acids (PUFAs) on mucosal levels of leukotrienes (LTs) and lipid peroxide (LPO), and on mucosal microcirculation, in rats with experimental colitis induced by dextran sulfate sodium (DSS). METHODS:We fed Wistar rats a perilla oil-enriched diet containing alph...

journal_title：Digestion

authors： Shimizu T,Igarashi J,Ohtuka Y,Oguchi S,Kaneko K,Yamashiro Y

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIM:Studies have demonstrated an important role for endogenous PG and NO in the healing of chronic gastric ulcers. We investigated the effects of COX and NOS inhibitors on the healing of duodenal ulcers, in comparison with gastric ulcers, in rats. METHODS:Gastric and duodenal ulcers were induced by serosal ...

journal_title：Digestion

authors： Araki H,Komoike Y,Matsumoto M,Tanaka A,Takeuchi K

更新日期：2002-01-01 00:00:00