Etiology and Morphology Impact on the Clinical Course of Chronic Pancreatitis.

abstract：:Carbonic anhydrase (CA) was found to be equally susceptible to direct inhibition by ethanol, whether the enzyme originated from homogenates of rabbit gastric, duodenal, or ileal mucosa. When gastric mucosa was separated into a soluble (cytoplasmic) and a membrane fraction, the membrane CA was more susceptible to ethan...

journal_title：Digestion

authors： Newsome LR,Leitch GJ

更新日期：1978-07-01 00:00:00

abstract：:We studied the functional coupling between antral somatostatin and gastrin cells in pigs using isolated perfused preparations of the antrum with intact supply of the vagus nerves. Luminal acidification significantly inhibited gastrin secretion to 61 +/- 3% of basal secretion and increased somatostatin output 9-fold. I...

journal_title：Digestion

authors： Holst JJ,Orskov C,Seier-Poulsen S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Transition-related healthcare intervention has recently been receiving worldwide attention. Given the increasing incidence of pediatric inflammatory bowel disease (IBD) and its lifelong impact, transitional care has become an important issue. In Japan, guidelines to support the autonomy of IBD patients durin...

journal_title：Digestion

authors： Kumagai H,Suzuki Y,Shimizu T

更新日期：2021-01-01 00:00:00

abstract：:The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar...

journal_title：Digestion

authors： Burroughs AK,Malagelada R

更新日期：1993-01-01 00:00:00

abstract：AIM:Although pectin, a dietary fibre, has been suggested to possess some trophic effects on the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the effects of pectin on rat intestinal cell proliferation and the intraluminal environment. METHODS:Control and pectin-fed rats were given a f...

journal_title：Digestion

authors： Fukunaga T,Sasaki M,Araki Y,Okamoto T,Yasuoka T,Tsujikawa T,Fujiyama Y,Bamba T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:An abnormal immune response may play a pathogenetic role in chronic pancreatitis. However, to date characterization of the systemic immunological changes in patients with chronic pancreatitis has not been undertaken. METHODS:Lymphocyte phenotypes and proliferation ((3)H-thymidine) after stimulation with mit...

journal_title：Digestion

authors： Ockenga J,Jacobs R,Kemper A,Benschop RJ,Schmidt RE,Manns MP

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:Endoscopic definitions and management of Barrett's esophagus vary widely among countries. To examine the current situation regarding diagnosis, epidemiology, management and treatment of Barrett's esophagus in East Asian countries using a questionnaire-based survey. METHODS:Representative members of the...

journal_title：Digestion

authors： Ishimura N,Amano Y,Sollano JD,Zhu Q,Kachintorn U,Rani AA,Hahm KB,Takahashi S,Arakawa T,Joh T,Matsumoto T,Naito Y,Suzuki H,Ueno F,Fukudo S,Fujiwara Y,Kamiya T,Uchiyama K,Kinoshita Y,IGICS Study Group.

更新日期：2012-01-01 00:00:00

abstract：:Rabbit duodenal and jejunal brush-border membrane vesicle integrity, fluidity and passive proton permeability were studied after in vitro exposure to deoxycholate, glycodeoxycholate or taurodeoxycholate. Duodenal and jejunal membrane mean vesicle volume [0.54 (0.05) and 0.54 (0.03) microliters/mg, mean values with SE ...

journal_title：Digestion

authors： Zhao DL,Hirst BH

更新日期：1990-01-01 00:00:00

abstract：:Buffalo strain male and female rats were given methylazoxymethanol acetate (20% solution) intraperitoneally 20 mg/kg body weight weekly for 9 weeks, and killed 27 weeks later. Carcinomas of the large intestine, predominantly in the descending colon, developed in some of the rats. The incidence was higher in male than ...

journal_title：Digestion

authors： Reuber MD

更新日期：1976-01-01 00:00:00

abstract：:Retractile mesenteritis is an extremely rare disease characterised by a non-specific inflammatory and fibrotic process of the mesenteric adipose tissue, which is usually accompanied by pain and a variety of other abdominal symptoms. We describe here the case of a patient with retractile mesenteritis presenting with pr...

journal_title：Digestion

authors： Papadaki HA,Kouroumalis EA,Stefanaki K,Roussomoustakaki M,Daskalogiannaki ME,Reppa D,Eliopoulos GD

更新日期：2000-01-01 00:00:00

abstract：:A case of sporadic, histamine-producing gastric carcinoid with liver metastases is reported. The patient was treated with somatostatin analogue (octreotide) combined with cortisone and blockade of histamine receptors prior to surgery, which included subtotal gastrectomy, excision of lymph node metastases and superfici...

journal_title：Digestion

authors： Kölby L,Wängberg B,Ahlman H,Jansson S,Forssell-Aronsson E,Erickson JD,Nilsson O

更新日期：1998-01-01 00:00:00

abstract：:Electrophoretic studies of inactive ductal pancreatic secretions, collected on five successive days following operation, demonstrated up to 18 protein bands. Comparison of the densitometric scans on the first and fourth days was as follows: the patterns from different individuals appeared similar during the periods of...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND AIM:Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients...

journal_title：Digestion

authors： Ciccone A,Gabrieli D,Cardinale R,Di Ruscio M,Vernia F,Stefanelli G,Necozione S,Melideo D,Viscido A,Frieri G,Latella G

更新日期：2019-01-01 00:00:00

abstract：:Mucosal intestinal cells migrate and differentiate simultaneously as they move out of the crypts to their functional site along the villus. Interactions between the enterocyte basal membrane domain and the extracellular intestinal basement membrane (IBM) have been suggested to be essential to both cell migration and d...

journal_title：Digestion

authors： Wilson JR,Weiser MM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gallbladder mucus itself has been recognized to play an important role in gallstone development. Despite the diverse mechanisms of stone induction and the differences in stone composition, there is a quantitative increase in the epithelial mucus production period before stone formation. As brown pigment...

journal_title：Digestion

authors： Sheen PC,Lee KT,Liu YE

更新日期：1998-11-01 00:00:00

abstract：:Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagn...

journal_title：Digestion

authors： Okubo M,Tahara T,Shibata T,Nakamura M,Kamiya Y,Yoshioka D,Maeda Y,Yonemura J,Ishizuka T,Arisawa T,Hirata I

更新日期：2011-01-01 00:00:00

abstract：:At 1 year after a first resection, up to 80% of patients show an endoscopic recurrence, 10-20% have clinical relapse, and 5% have surgical recurrence. Smoking is one of the most important risk factors for postoperative recurrence. Preoperative disease activity and the severity of endoscopic lesions in the neoterminal ...

journal_title：Digestion

authors： Froehlich F,Juillerat P,Felley C,Mottet C,Vader JP,Burnand B,Michetti P,Gonvers JJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Determining the depth of invasion is important when considering therapeutic strategies for early gastric cancer (EGC). We determined the effects of learning the non-extension sign, that is, an index of T1b2 in EGC, on identifying its depth of invasion. METHODS:Endoscopic images of 40 EGC cases (20 showing p...

journal_title：Digestion

authors： Takeda T,So S,Sakurai T,Nakamura S,Yoshikawa I,Yada S,Itaba S,Yamagata H,Akiho H,Takatsu N,Wada Y,Ohtsu K,Nagahama T,Yao K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gastric cancers are characterized by a heterogeneously hypoxic environment. Hypoxia might stimulate the malignant potential of cancer cells. The purpose of our study was to clarify the significance of hypoxia in gastric carcinoma by evaluating the expression of a hypoxic marker, namely carbonic anhydras...

journal_title：Digestion

authors： Kato Y,Yashiro M,Noda S,Kashiwagi S,Matsuoka J,Fuyuhiro Y,Doi Y,Hirakawa K

更新日期：2010-01-01 00:00:00

abstract：:6 patients with Crohn's disease for 1-14 years have been treated with plasmapheresis for periods of up to 6 months. The symptoms of the one newly diagnosed patient were controlled by plasmapheresis alone, and 5 steroid-dependent patients were able to reduce their steroid requirements. During the study period, 13 clini...

journal_title：Digestion

authors： Holdstock GE,Fisher JA,Hamblin TJ,Loehry C

更新日期：1979-01-01 00:00:00

abstract：:There is no generally accepted treatment in the irritable bowel syndrome (IBS), probably because of a lack of convincing therapeutic trials. In the present study, 120 outpatients with IBS participated in a prospective randomized therapeutic trial. According to a double-blind design, 40 patients received 400 mg/day meb...

journal_title：Digestion

authors： Kruis W,Weinzierl M,Schüssler P,Holl J

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The present study aimed to evaluate the micronucleus (MN), nucleoplasmic bridges (NPBs) and nuclear buds (NBUDs) in the mitogen-stimulated lymphocytes of patients with ulcerative colitis (UC). In addition, we assessed MN frequency in exfoliated colonic epithelial cells obtained from both the diseased and heal...

journal_title：Digestion

authors： Karaman A,Hamurcu Z,Donmez H,Bitken N,Karaman H,Baskol M,Gursoy S,Guven K,Ozbakir O,Yucesoy M

更新日期：2012-01-01 00:00:00

abstract：:Repeated intravenous injections of 2.0 clinical units (CU) secretin per kg body weight showed no effect on jejunal glucose absorption and net water movement in perfusion studies in vivo. The in vitro uptake of galactose and 3-O-methylglucose was not altered by a secretin load given 12 min before sacrifice. The values ...

journal_title：Digestion

authors： Böhmer R,Rommel K

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Grading gastric mucosal atrophy in antrum biopsy specimens remains a controversial subject because of limitations in interobserver agreement. We previously described a reliable, quantitative method for grading atrophy of the corpus mucosa with excellent reproducibility and good correlation with the Sydn...

journal_title：Digestion

authors： van Grieken NC,Meijer GA,Kale I,Bloemena E,Lindeman J,Offerhaus GJ,Meuwissen SG,Baak JP,Kuipers EJ

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Supramaximal concentrations of cholecystokinin (CCK) or cerulein induce the intracellular activation of trypsinogen and the transcription factor NF-kappaB, a key regulator of inflammatory gene expression. Both events occur early in the development of an acute pancreatitis. The aim of this study was ...

journal_title：Digestion

authors： Tando Y,Algül H,Schneider G,Weber CK,Weidenbach H,Adler G,Schmid RM

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...

journal_title：Digestion

authors： Takeshita E,Sakata Y,Hara M,Akutagawa K,Sakata N,Endo H,Ohyama T,Matsunaga K,Yoshioka T,Kawakubo H,Tanaka Y,Shirai S,Ito Y,Tsuruoka N,Iwakiri R,Kusano M,Fujimoto K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:Previous studies have reported small intestinal lesions in patients with portal hypertensive disease. However, the etiology of these lesions is not clear, as portal venous pressure was not measured in any of these studies. The aim of this study is to clarify the association between small intestinal lesio...

journal_title：Digestion

authors： Takahashi Y,Fujimori S,Narahara Y,Gudis K,Ensaka Y,Kosugi Y,Maki K,Suzuki M,Matsushita Y,Fukuda T,Kanazawa H,Sakamoto C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is a continuous diseases spectrum associated with obesity, type 2 diabetes, insulin resistance, and hyperlipidemia. Simple hepatic steatosis may progress to nonalcoholic steatohepatitis (NASH), even fibrosis and cirrhosis, and finally hepatocellular carcinoma. In rece...

journal_title：Digestion

authors： Zhong F,Zhou X,Xu J,Gao L

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...

journal_title：Digestion

authors： Wen J,Liu Q,Song J,Tong M,Peng L,Liang H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The incidence of esophageal cancer is markedly increased in patients with head and neck cancer, and the presence of esophageal cancer is associated with reduced survival rates. AIMS:We investigated whether the results of screening for esophageal cancer in patients with head and neck cancer using chromoendos...

journal_title：Digestion

authors： Moschler O,Spahn TW,Middelberg-Bisping C,Grosse-Thie W,Christoph B,Kloeppel G,Mueller MK

更新日期：2006-01-01 00:00:00