Lactulose is highly potential in prophylaxis of hepatic encephalopathy in patients with cirrhosis and upper gastrointestinal bleeding: results of a controlled randomized trial.

abstract：:There are many controversies concerning the treatment of hemorrhages of the upper gastrointestinal tract. In order to determine whether some currently used drugs, such as somatostatin (SST) and ranitidine, may be useful in the control of hemorrhages, we have conducted a controlled (not blind) study with alternate assi...

journal_title：Digestion

authors： Coraggio F,Bertini G,Catalano A,Scarpato P,Gualdieri L

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) is a standard treatment for tumors of the gastrointestinal tract. We developed a self-completion method of ESD using Endosaber to eliminate the need for an additional device or human assistance during the procedure. The aim of this study was to evaluate the technical fe...

journal_title：Digestion

authors： Esaki M,Minoda Y,Wada M,Sakisaka S,Tsuruta S,Hosokawa T,Matsuguchi T,Ichijima R,Suzuki S,Tamura Y,Iwao A,Yamakawa S,Irie A,Ihara E,Ogawa Y

更新日期：2019-09-27 00:00:00

abstract：BACKGROUND/AIMS:Currently, a split-dose of polyethylene glycol (PEG) is the mainstay of bowel preparation due to its tolerability, bowel-cleansing action, and safety. However, bowel preparation with PEG is suboptimal because residual fluid reduces the polyp detection rate and requires a more thorough colon inspection. ...

journal_title：Digestion

authors： Kim HJ,Kim TO,Shin BC,Woo JG,Seo EH,Joo HR,Heo NY,Park J,Park SH,Yang SY,Moon YS,Shin JY,Lee NY

更新日期：2012-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:Autoimmune hepatitis (AIH) is a relatively rare cause of liver dysfunction and may lead in some cases to acute liver failure (ALF). The aim of our study was to evaluate the clinical course and outcome of patients with AIH-induced ALF. METHODS:We retrospectively enrolled 32 patients with AIH-induced ALF...

journal_title：Digestion

authors： Anastasiou OE,Dogan-Cavus B,Kucukoglu O,Baba H,Kahraman A,Gerken G,Schramm C,Canbay A

更新日期：2018-01-01 00:00:00

abstract：:Leukocyte infiltration in the pancreas is involved in the aggravation of acute pancreatitis from edematous phase into necrotic change, and mild disease into severe disease; however, the mechanism responsible for leukocyte accumulation is not fully understood. This study was designed to clarify the mechanism underlying...

journal_title：Digestion

authors： Yamauchi J,Sunamura M,Shibuya K,Takeda K,Kobari M,Matsuno S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Fecal lactoferrin has been introduced as a useful tool for the diagnosis and monitoring of inflammatory bowel disease (IBD). The aim of this study was to assess if fecal lactoferrin can be employed to predict or estimate the effect of granulocyte and monocyte adsorptive apheresis (GMA) in ulcerative colitis ...

journal_title：Digestion

authors： Hashiguchi K,Takeshima F,Akazawa Y,Matsushima K,Minami H,Machida H,Yamaguchi N,Shiozawa K,Ohba K,Ohnita K,Ichikawa T,Isomoto H,Nakao K

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

journal_title：Digestion

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Incidence of cholangiocarcinoma (CCA) in western countries is rising. In the palliative setting, chemotherapy is the only established treatment. The evidence for other treatments including locoregional therapy is low. However, such individual treatments are offered in a real-world setting. The aim of this st...

journal_title：Digestion

authors： Koch C,Franzke C,Bechstein WO,Schnitzbauer AA,Filmann N,Vogl T,Gruber-Rouh T,Zeuzem S,Waidmann O,Trojan J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:In order to perform small bowel manometry studies in man, the probes have to be guided through the upper gastrointestinal tract. This is usually controlled by fluoroscopy, but a method that allows to place the tubes without X-rays is obviously desirable. METHODS:A new method that controls tube placing by so...

journal_title：Digestion

authors： V Schönfeld J

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Few prospective population-based studies have been carried out on the incidence of inflammatory bowel disease (IBD). In a population-based study of pediatric IBD in southeastern Norway, patients <16 years at the time of diagnosis were followed up prospectively. The study reports on changes in diagnosis and c...

journal_title：Digestion

authors： Størdal K,Jahnsen J,Bentsen BS,Moum B

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:In patients with active ulcerative colitis (UC), pharmacologics, although initially effective in most patients, are associated with refractoriness, loss of response or unfavourable side effects as additional morbidity factors. Depletion of myeloid lineage leucocytes like the CD14(+)CD16(+) monocyte phen...

journal_title：Digestion

authors： Iida T,Ikeya K,Kato M,Abe J,Yamamoto M,Watanabe F,Sugimoto K,Hanai H

更新日期：2017-01-01 00:00:00

abstract：:Discussion over the role of enzyme therapy in patients with acute pancreatitis is based upon theoretical considerations rather than hard data. In this respect, it differs little from most other treatments used in the management of acute pancreatitis, although, in the case of enzyme treatment, the lack of data results ...

journal_title：Digestion

authors： McMahon MJ

更新日期：1993-01-01 00:00:00

abstract：:The rates of intracellular transport of newly synthesized amylase, lipase, trypsinogen and chymotrypsinogen were compared in the anaesthesized rat pancreas by measuring their rates of secretion while keeping their relative rates of synthesis in a steady state. It is concluded that pancreatic proteins are not transport...

journal_title：Digestion

authors： Iovanna J,Giorgi D,Dagorn JC

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...

journal_title：Digestion

authors： Takeshita E,Sakata Y,Hara M,Akutagawa K,Sakata N,Endo H,Ohyama T,Matsunaga K,Yoshioka T,Kawakubo H,Tanaka Y,Shirai S,Ito Y,Tsuruoka N,Iwakiri R,Kusano M,Fujimoto K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a median 5-year survival of <8%. At the time of diagnosis, a vast majority of pancreatic cancer patients were found to be with either metastatic spread of the disease or locally advanced tumors. Despite relatively low efficacy, ge...

journal_title：Digestion

authors： Ellenrieder V,König A,Seufferlein T

更新日期：2016-01-01 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND/AIMS:Many studies have recently been published on acute pancreatitis; however, few large-sample studies have been focused on the risk factors for deaths in severe acute pancreatitis. To address this issue, the present study was intended to assess etiology, severity, and mortality of acute pancreatitis in the...

journal_title：Digestion

authors： Bai Y,Jia L,Wang B,Yang B,Wang L,Shi X,Zhang W,Liu Y,Zou D,Li Z

更新日期：2007-01-01 00:00:00

abstract：:The effects of two recently developed gastrin receptor antagonists, PD 136450 and L-365,260, on pentagastrin-stimulated acid secretion were investigated in rats. PD 136450 at a dose of 6 mg/kg s.c. (9.6 mumol) completely abolished acid secretion induced by pentagastrin. The inhibition of 18 mg/kg PD 136450 s.c. lasted...

journal_title：Digestion

authors： Eissele R,Koop H,Bothe-Sandfort E,Arnold R

更新日期：1992-01-01 00:00:00

abstract：:Differential absorption of D-xylose and 3-O-methyl-D-glucose, and unmediated intestinal permeation of lactulose and L-rhamnose has been investigated in 14 patients with diarrhoea following tropical exposure and in 16 healthy control subjects. Five had malabsorption of fat, D-xylose and B12 ('tropical malabsorption' (T...

journal_title：Digestion

authors： Cook GC,Menzies IS

更新日期：1986-01-01 00:00:00

abstract：:Putrescine, the product of the ornithine decarboxylase (ODC)-catalyzed reaction, stimulates macromolecular synthesis in a duodenal crypt cell line, IEC-6 cells, grown in culture. In addition, supplementation of medium with putrescine alone reverses the inhibition of proliferation produced by inhibition of ODC with dif...

journal_title：Digestion

authors： Seidel ER,Ginty DD

更新日期：1990-01-01 00:00:00

abstract：:Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients. However, because reflux oesophagitis relapses rapidly when short-term treatment is dis...

journal_title：Digestion

authors： Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：:N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine HCl (DPPE) is an antihistamine with a unique profile of activity in the stomach. It is antisecretory and blocks the formation of experimental cold/stress- and ethanol-induced gastric lesions, as well as cysteamine-induced duodenal ulcers in a fashion more potent than o...

journal_title：Digestion

authors： Glavin GB,Gerrard JM

更新日期：1990-01-01 00:00:00

abstract：:Cell renewal in the duodenal mucosa of Mastomys was studied by autoradiography 1 and 24 h after intraperitoneal injection of tritiated thymidine. Non-specific duodenitis and duodenal ulceration were produced with a continuous infusion of histamine. Mucosal renewal in the duodenum of 30 control Mastomys was compared wi...

journal_title：Digestion

authors： Smedley FH,Rimmer J,Samanidis A,Wastell C

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIM:Previous studies have reported small intestinal lesions in patients with portal hypertensive disease. However, the etiology of these lesions is not clear, as portal venous pressure was not measured in any of these studies. The aim of this study is to clarify the association between small intestinal lesio...

journal_title：Digestion

authors： Takahashi Y,Fujimori S,Narahara Y,Gudis K,Ensaka Y,Kosugi Y,Maki K,Suzuki M,Matsushita Y,Fukuda T,Kanazawa H,Sakamoto C

更新日期：2012-01-01 00:00:00

abstract：:The elimination of endogenous carboxyamidated and glycine-extended gastrins in liver and gut was studied before and after feeding in 14 anesthetized pigs. Before the meal, liver and gut extractions were nonsignificant. After feeding, the release rate of amidated gastrin increased from 7.5 +/- 2.6 to 21.9 +/- 5.3 pmol/...

journal_title：Digestion

authors： Hansen CP,Stadil F,Rehfeld JF

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Defective epithelial barrier has been implicated in the pathogenesis of irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was to investigate gut permeability in patients with inactive ulcerative colitis (UC) and in patients with IBS. METHODS:IBS patients of the diarr...

journal_title：Digestion

authors： Gecse K,Róka R,Séra T,Rosztóczy A,Annaházi A,Izbéki F,Nagy F,Molnár T,Szepes Z,Pávics L,Bueno L,Wittmann T

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...

journal_title：Digestion

authors： Pezzilli R,Billi P,Platè L,Bongiovanni F,Morselli Labate AM,Miglioli M

更新日期：1994-01-01 00:00:00

abstract：:The prognosis for the acute healing of patients with persistent, erosive or ulcerative reflux oesophagitis depends upon the choice of drug treatment as well as the severity of the initial oesophagitis. The results of this study show that omeprazole, 40 mg once daily (n = 51), is more effective than ranitidine, 300 mg ...

journal_title：Digestion

authors： Lundell L

更新日期：1990-01-01 00:00:00

abstract：:The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar...

journal_title：Digestion

authors： Burroughs AK,Malagelada R

更新日期：1993-01-01 00:00:00