The role of drug treatment in variceal bleeding.

abstract：:Cell renewal in the duodenal mucosa of Mastomys was studied by autoradiography 1 and 24 h after intraperitoneal injection of tritiated thymidine. Non-specific duodenitis and duodenal ulceration were produced with a continuous infusion of histamine. Mucosal renewal in the duodenum of 30 control Mastomys was compared wi...

journal_title：Digestion

authors： Smedley FH,Rimmer J,Samanidis A,Wastell C

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma is one of the most lethal types of cancer with a 5-year survival rate of around 7%. Due to the relatively poor prognosis, the potential need of an effective chemoprevention is highly needed. SUMMARY:Different risk factors like smoking or hereditary tumour syndromes should be...

journal_title：Digestion

authors： Benzel J,Fendrich V

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate whether the neuronal form of nitric oxide (NO) synthase (nNOS) in gastric mucosa differed from nNOS in the brain in subcellular distribution or antigenicity, and to determine the relative activity of the endothelial form of NO synthase (eNOS) and nNOS in gastric mucosa. METHODS:Subcellul...

journal_title：Digestion

authors： Price K,Hanson P

更新日期：1998-07-01 00:00:00

abstract：:Several previous studies have shown that the plasma concentration of gamma-amino-butyric acid (GABA) is markedly increased in patients with hepatic encephalopathy, and it has been suggested that decreased metabolism of peripheral GABA might contribute to the cerebral dysfunctions observed. In the present study, plasma...

journal_title：Digestion

authors： Löscher W,Kretz FJ,Karavias T,Dillinger U

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:It has been demonstrated that cryptogenic pyogenic liver abscess (PLA) is associated with colonic mucosal defect, especially colorectal cancer (CRC). Therefore, the screening of CRC in patients with cryptogenic PLA is important. This study was to investigate whether computed tomographic colonography (CT...

journal_title：Digestion

authors： Jang DK,Jeong SH,Lee SH,Lee M,Jang ES,Kim JW,Hwang JH,Ryu JK,Kim YT,Lee YJ,Lee KH,Kim YH

更新日期：2014-01-01 00:00:00

abstract：:The elimination of endogenous carboxyamidated and glycine-extended gastrins in liver and gut was studied before and after feeding in 14 anesthetized pigs. Before the meal, liver and gut extractions were nonsignificant. After feeding, the release rate of amidated gastrin increased from 7.5 +/- 2.6 to 21.9 +/- 5.3 pmol/...

journal_title：Digestion

authors： Hansen CP,Stadil F,Rehfeld JF

更新日期：1996-01-01 00:00:00

abstract：:Plasma lactate and urate concentrations, following 50 g oral fructose, were compared in 12 control subjects and 13 patients with liver disease. No serious adverse effects occurred following fructose ingestion, and in neither group did the plasma lactate concentration exceed 5.2 mmol/l. There were no significant differ...

journal_title：Digestion

authors： Douglas JG,Beckett GJ

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND/AIMS:Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide. We have described thiamine deficiency in patients with small intestinal bacterial overgrowth after gastric bypass. We hypothesized that symptoms of thiamine deficiency are common after gastric bypass. The aims of this study...

journal_title：Digestion

authors： Shah HN,Bal BS,Finelli FC,Koch TR

更新日期：2013-01-01 00:00:00

abstract：:We evaluated a hand-held scintillation detector for intra-operative localisation of somatostatin-receptor-positive tumours in situ, and after excision, as an addition to preoperative scintigraphy with [111In-DTPA-Phe1]octreotide. Using the hand-held detector, the suspect tumour/normal tissue ratio R(in situ) between m...

journal_title：Digestion

authors： Ahlman H

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a median 5-year survival of <8%. At the time of diagnosis, a vast majority of pancreatic cancer patients were found to be with either metastatic spread of the disease or locally advanced tumors. Despite relatively low efficacy, ge...

journal_title：Digestion

authors： Ellenrieder V,König A,Seufferlein T

更新日期：2016-01-01 00:00:00

abstract：:An improved GLC method was employed to study individual serum bile acids in 14 control subjects after a 12-hour fast followed by a standard fatty meal. Peripheral venous blood samples were obtained at 15-min intervals for up to 2 h in 7 subjects, and 4 h in 2 subjects. The fasting total bile acids, and cholic:chenodeo...

journal_title：Digestion

authors： Pennington CR,Ross PE,Bouchier IA

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND AIM:Along with the widespread use of eradication for Helicobacter pylori (H. pylori), the incidence of gastric cancer after eradication has also been increasing. There is a need for clarification of the clinical and biological characteristics of these neoplasms. PATIENTS AND METHODS:We studied 27 cases ...

journal_title：Digestion

authors： Matsuo T,Ito M,Tatsugami M,Boda T,Takata S,Tanaka S,Chayama K

更新日期：2012-01-01 00:00:00

abstract：:The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinom...

journal_title：Digestion

authors： Lehmann FG,Kornacher J

更新日期：1975-01-01 00:00:00

abstract：:In an attempt to evaluate a possible correlation between cryptogenic chronic liver disease and a present or past hepatitis B virus (HBV) infection, we studied 17 patients with hepatitis B surface antigen (HBsAg)-negative, nonalcoholic chronic liver disease; 9 of them were positive for serum HBsAg detected by a solid-p...

journal_title：Digestion

authors： Diodati G,Pontisso P,Bonetti P,Stenico D,Noventa F,Alberti A,Realdi G

更新日期：1988-01-01 00:00:00

abstract：:To assess the feasibility of a prospective incidence study of inflammatory bowel disease (IBD), the registration methods and incidence figures during 1990 were evaluated. The study was a collaboration between 14 hospitals in an area of close to one million inhabitants. Common diagnostic criteria for ulcerative colitis...

journal_title：Digestion

authors： Moum B,Vatn MH,Ekbom A,Fausa O,Aadland E,Lygren I,Sauar J,Schulz T

更新日期：1995-01-01 00:00:00

abstract：:Indicators of net water movement are used in a variety of intestinal transport studies. Such indicators should be virtually unabsorbed under study conditions. The effects of stimuli that alter intestinal mass on indicator recovery have not been examined. We used the male albino rat to study the effects of food restric...

journal_title：Digestion

authors： Miller DL,Schedl HP,Bouska J,Phillips SF

更新日期：1987-01-01 00:00:00

abstract：:The aim of the study was to define the effects of sex, age, smoking, alcohol, analgesic ingestion, and treatment method whereby healing was initially induced on the prognosis of patients with a chronic duodenal ulcer (DU). 122 patients were assessed 1 year after the endoscopic demonstration of a DU. Two outcome variab...

journal_title：Digestion

authors： Piper DW,McIntosh JH,Hudson HM

更新日期：1985-01-01 00:00:00

abstract：:This work describes a new preparation of dog pancreatic acini which were used to study amylase release in response to various secretagogues. Neither secretin nor vasoactive intestinal peptide stimulated amylase release from acini. Caerulein, carbachol and human synthetic gastrin G17 stimulated amylase release with the...

journal_title：Digestion

authors： Bommelaer G,Rozental G,Bernier C,Vaysse N,Ribet A

更新日期：1981-01-01 00:00:00

abstract：:Pancreatoduodenectomy (PD) may be followed by serious complications chiefly associated with exocrine pancreatic secretion. Somatostatin and its analogues are able to inhibit pancreatic secretion and thus have been advocated for the prevention of complications following pancreatic surgery. In four published multicentri...

journal_title：Digestion

authors： Gouillat C

更新日期：1999-01-01 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：:Putrescine, the product of the ornithine decarboxylase (ODC)-catalyzed reaction, stimulates macromolecular synthesis in a duodenal crypt cell line, IEC-6 cells, grown in culture. In addition, supplementation of medium with putrescine alone reverses the inhibition of proliferation produced by inhibition of ODC with dif...

journal_title：Digestion

authors： Seidel ER,Ginty DD

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:The benefits of colonoscopy in reducing colorectal cancer (CRC) risk for patients over 75 years are controversial. We aimed to determine whether colonoscopy use is associated with a decreased risk of CRC in patients 76-85 years old in the United States (US). PATIENTS AND METHODS:All patients in the Med...

journal_title：Digestion

authors： Wang YR,Cangemi JR,Loftus EV Jr,Picco MF

更新日期：2016-01-01 00:00:00

abstract：:Mucosal intestinal cells migrate and differentiate simultaneously as they move out of the crypts to their functional site along the villus. Interactions between the enterocyte basal membrane domain and the extracellular intestinal basement membrane (IBM) have been suggested to be essential to both cell migration and d...

journal_title：Digestion

authors： Wilson JR,Weiser MM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...

journal_title：Digestion

authors： Wen J,Liu Q,Song J,Tong M,Peng L,Liang H

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Few prospective population-based studies have been carried out on the incidence of inflammatory bowel disease (IBD). In a population-based study of pediatric IBD in southeastern Norway, patients <16 years at the time of diagnosis were followed up prospectively. The study reports on changes in diagnosis and c...

journal_title：Digestion

authors： Størdal K,Jahnsen J,Bentsen BS,Moum B

更新日期：2004-01-01 00:00:00

abstract：:This study was designed to determine the influence of acetazolamide, a potent inhibitor of carbonic anhydrase, on the formation of gastric mucosal lesions induced by acidified aspirin (ASA) or absolute ethanol and on gastric cytoprotection induced by prostaglandin E2 (PGE2). Acetazolamide prevented dose-dependently et...

journal_title：Digestion

authors： Konturek SJ,Brzozowski T,Piastucki I,Radecki T

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND/AIMS:As opposed to regular C-reactive protein (CRP) assays, the introduction of high-sensitivity ones has enabled us to detect low grade inflammation in patients with inflammatory bowel disease (IBD). We addressed the subject of the degree of correlation between the concentration of high-sensitivity CRP (hs-...

journal_title：Digestion

authors： Zilberman L,Maharshak N,Arbel Y,Rogowski O,Rozenblat M,Shapira I,Berliner S,Arber N,Dotan I

更新日期：2006-01-01 00:00:00

abstract：:Activation of enzyme phospholipase A2 (EC 3.1.1.4), the major liberator of arachidonic acid, has been proposed as a component in the pathogenesis of inflammatory bowel disease. To test the hypothesis that phospholipase A2 activity is increased in ulcerative colitis, enzyme activity was investigated in colonic biopsies...

journal_title：Digestion

authors： Almer S,Franzén L,Olaison G,Smedh K,Ström M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:Transgenic mice overexpressing hepatitis B x protein (HBx) show an increased susceptibility to mutations if exposed to mutagens. Also involved in HBx signalling, reactive oxygen intermediates (ROI) can induce DNA adducts such as 8-hydroxy-2'-deoxyguanosine that can in turn lead to G/T transversion mutat...

journal_title：Digestion

authors： Gehrke R,Brauchle MA,Reifenberg K,Hildt E,Gruetzner U,Schmitz V,Schlicht HJ,Hofschneider PH,Caselmann WH,Rabe C

更新日期：2004-01-01 00:00:00

abstract：:Hepatitis B surface antigen (HBsAg)-associated receptors for polymerized human serum albumin (RpHSA) are assumed to mediate viral attachment to hepatocytes in hepatitis B virus (HBV) infection. RpHSA was found to be coded by the pre-S region of HBV genome. Recently, the antiviral effect of recombinant leukocyte alpha-...

journal_title：Digestion

authors： Gerken G,Manns M,Hess G,Meyer zum Büschenfelde KH

更新日期：1987-01-01 00:00:00