Plasma lactate and urate concentrations following oral fructose in patients with liver disease.

Abstract:

:Plasma lactate and urate concentrations, following 50 g oral fructose, were compared in 12 control subjects and 13 patients with liver disease. No serious adverse effects occurred following fructose ingestion, and in neither group did the plasma lactate concentration exceed 5.2 mmol/l. There were no significant differences in plasma lactate and urate concentration between the patients or controls in either the fasting state or following fructose ingestion. It is concluded that oral fructose, in contrast to intravenous fructose infusion, is unlikely to produce lactic acidosis in patients with liver disease. Also an oral fructose tolerance test based on the measurement of post-fructose plasma lactate or urate concentrations is of no value as a test of liver function.

journal_name

Digestion

journal_title

Digestion

authors

Douglas JG,Beckett GJ

doi

10.1159/000198843

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

263-8

issue

4

eissn

0012-2823

issn

1421-9867

journal_volume

25

pub_type

杂志文章
  • Constipation in patients with thiamine deficiency after Roux-en-Y gastric bypass surgery.

    abstract:BACKGROUND/AIMS:Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide. We have described thiamine deficiency in patients with small intestinal bacterial overgrowth after gastric bypass. We hypothesized that symptoms of thiamine deficiency are common after gastric bypass. The aims of this study...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000353245

    authors: Shah HN,Bal BS,Finelli FC,Koch TR

    更新日期:2013-01-01 00:00:00

  • What determines the later clinical course of patients who do not undergo colectomy at the first attack? A Japanese cohort study on ulcerative colitis.

    abstract:BACKGROUND/AIMS:Several earlier studies on factors predicting the long-term outcome of ulcerative colitis only encompassed treatment failure for one severe episode, or suffered from a lack of multivariate analyses. We aimed to identify factors assessable at diagnosis or after the first induction therapy which predicted...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000229773

    authors: Shiga H,Takagi S,Inoue R,Kinouchi Y,Ohkubo T,Takahashi S,Negoro K,Yokoyama H,Kato S,Fukushima K,Hiwatashi N,Shimosegawa T

    更新日期:2010-01-01 00:00:00

  • Leptin modulates the inflammatory response in acute pancreatitis.

    abstract:BACKGROUND:Leptin is a pleiotropic hormone that is involved in the regulation of food intake and body weight. Recent findings demonstrated that leptin receptors are present in the pancreas but the involvement of leptin in pancreatitis remains unknown. The aim of the present study was: (1) to assess plasma leptin levels...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000064935

    authors: Konturek PC,Jaworek J,Maniatoglou A,Bonior J,Meixner H,Konturek SJ,Hahn EG

    更新日期:2002-01-01 00:00:00

  • Pancreatitis-associated protein (HIP/PAP) gene expression is upregulated in NOD mice pancreas and localized in exocrine tissue during diabetes.

    abstract::We have previously shown a specific significant overexpression in the exocrine pancreatic tissue of two members of the regenerating gene multifamily: reg I and reg II in the non-obese diabetic (NOD) mouse during active diabetogenesis. To strengthen the hypothesis that the overexpression of these genes may represent a ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000048867

    authors: Baeza N,Sanchez D,Christa L,Guy-Crotte O,Vialettes B,Figarella C

    更新日期:2001-01-01 00:00:00

  • Submucosal fibrosis and basic-fibroblast growth factor-positive neutrophils correlate with colonic stenosis in cases of ulcerative colitis.

    abstract:BACKGROUND AND AIMS:The frequency of benign stenosis in ulcerative colitis (UC) is low, reported as being 3.2-11.2%, with fibrosis in the submucosa or deeper pointed out as one of the causes. The aim of the present study was to assess stenosis in UC cases using immunostaining and to analyze differences between stenotic...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000320773

    authors: Yamagata M,Mikami T,Tsuruta T,Yokoyama K,Sada M,Kobayashi K,Katsumata T,Koizumi W,Saigenji K,Okayasu I

    更新日期:2011-01-01 00:00:00

  • Effects of n-3 polyunsaturated fatty acids and vitamin E on colonic mucosal leukotriene generation, lipid peroxidation, and microcirculation in rats with experimental colitis.

    abstract:AIMS:We investigated the effect of n-3 polyunsaturated fatty acids (PUFAs) on mucosal levels of leukotrienes (LTs) and lipid peroxide (LPO), and on mucosal microcirculation, in rats with experimental colitis induced by dextran sulfate sodium (DSS). METHODS:We fed Wistar rats a perilla oil-enriched diet containing alph...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000051872

    authors: Shimizu T,Igarashi J,Ohtuka Y,Oguchi S,Kaneko K,Yamashiro Y

    更新日期:2001-01-01 00:00:00

  • The possible role of bicarbonate in mucosal protection and peptic ulceration.

    abstract::The surface epithelial cells of the gastroduodenal mucosa are thought to be protected from the damaging effects of acid by a covering layer of mucus into which is secreted bicarbonate. It is proposed here that mucus acts as a true barrier to hydrogen ion diffusion, and that the role played by bicarbonate is to adjust ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198954

    authors: Vadgama P,Alberti KG

    更新日期:1983-01-01 00:00:00

  • Effect of wheat bran upon gastro-intestinal transit in germ-free and conventional rats.

    abstract::Germ-free and conventional rats were fed a semi-synthetic diet including 10% wheat bran for 1 month. They were compared to similar rats fed the same diet without bran. Transit of polyethylene glycol (PEG) 4000 was studied in giving the marker either in saline or in the diet. The presence of a bacterial flora was found...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199006

    authors: Riottot M,Sacquet E,Leprince C

    更新日期:1984-01-01 00:00:00

  • Therapy with omeprazole in patients with peptic ulcerations resistant to extended high-dose ranitidine treatment.

    abstract::94 patients with peptic ulcerations of duodenum, stomach, and esophagus, who did not respond to 3 or more months high-dose (450 or 600 mg) treatment with ranitidine, were treated orally with 40 mg omeprazole daily. After healing all patients were offered long-term maintenance therapy with the same dose for 5 years. In...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199610

    authors: Brunner G,Creutzfeldt W,Harke U,Lamberts R

    更新日期:1988-01-01 00:00:00

  • Celecoxib inhibits apurinic/apyrimidinic endonuclease-1 expression and prevents gastric cancer in Helicobacter pylori-infected mongolian gerbils.

    abstract:BACKGROUND AND AIMS:The aim of this study was to see whether administration of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, could prevent the development of gastric cancer via inhibition of apurinic/apyrimidinic endonuclease-1 (APE-1) expression induced by Helicobacter pylori infection. METHODS:70 Mongol...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000167978

    authors: Futagami S,Kawagoe T,Horie A,Shindo T,Hamamoto T,Suzuki K,Kusunoki M,Miyake K,Gudis K,Tsukui T,Crowe SE,Sakamoto C

    更新日期:2008-01-01 00:00:00

  • Platelet-activating factor acetylhydrolase activity in intestinal mucosa and plasma of patients with Crohn's disease.

    abstract::The activity of platelet-activating factor (PAF) acetylhydrolase in biopsy specimens of intestinal mucosa was compared in patients with Crohn's disease (n = 11) and controls (n = 6). In addition, PAF acetylhydrolase activity was determined in the plasma of Crohn patients (n = 30) and healthy subjects (n = 35). The act...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201376

    authors: Kald B,Smedh K,Olaison G,Sjödahl R,Tagesson C

    更新日期:1996-11-01 00:00:00

  • Mucosa-Associated Microbiota in the Gastrointestinal Tract of Healthy Japanese Subjects.

    abstract:BACKGROUND:The importance of microbiota infiltrating the gut mucus layer has been reported in the pathogenesis of various gastrointestinal and systemic diseases. However, little is known about the mucosa-associated microbiota (MAM) in healthy subjects. The present study aimed to clarify the characteristics of the gastr...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000496102

    authors: Kashiwagi S,Naito Y,Inoue R,Takagi T,Nakano T,Inada Y,Fukui A,Katada K,Mizushima K,Kamada K,Uchiyama K,Handa O,Ishikawa T,Itoh Y

    更新日期:2020-01-01 00:00:00

  • Cryptogenic chronic liver disease and serum or liver hepatitis B virus markers. Their possible correlations and etiologic significance.

    abstract::In an attempt to evaluate a possible correlation between cryptogenic chronic liver disease and a present or past hepatitis B virus (HBV) infection, we studied 17 patients with hepatitis B surface antigen (HBsAg)-negative, nonalcoholic chronic liver disease; 9 of them were positive for serum HBsAg detected by a solid-p...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199633

    authors: Diodati G,Pontisso P,Bonetti P,Stenico D,Noventa F,Alberti A,Realdi G

    更新日期:1988-01-01 00:00:00

  • Factors relevant to the prognosis of chronic duodenal ulcer.

    abstract::The aim of the study was to define the effects of sex, age, smoking, alcohol, analgesic ingestion, and treatment method whereby healing was initially induced on the prognosis of patients with a chronic duodenal ulcer (DU). 122 patients were assessed 1 year after the endoscopic demonstration of a DU. Two outcome variab...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199171

    authors: Piper DW,McIntosh JH,Hudson HM

    更新日期:1985-01-01 00:00:00

  • Effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients.

    abstract::This study was undertaken to evaluate the effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients. Sixteen cirrhotics were randomly assigned to metoclopramide (10 mg i.v.) or saline. Metoclopramide significantly decreased transmural variceal pressure (15.7% decr...

    journal_title:Digestion

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000200477

    authors: Taranto D,Suozzo R,de Sio I,Romano M,Caporaso N,Del Vecchio Blanco C,Coltorti M

    更新日期:1990-01-01 00:00:00

  • Carotid intima-media thickness is increased not only in non-alcoholic fatty liver disease patients but also in alcoholic fatty liver patients.

    abstract:BACKGROUND/AIMS:There are many reports of non-alcoholic fatty liver disease (NAFLD) patients with increased carotid intima-media thickness (IMT). However, there is little information about carotid IMT in alcoholic fatty liver disease (AFLD) patients. We aimed to compare the carotid IMT of NAFLD patients and AFLD patien...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000326854

    authors: Kim JH,Kim SY,Jung ES,Jung SW,Koo JS,Kim JH,Yeon JE,Kwon SY,Lee SW,Byun KS,Lee CH

    更新日期:2011-01-01 00:00:00

  • Does indomethacin activate healed gastric ulcers in the dog?

    abstract::Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198560

    authors: Okabe S,Tabata K

    更新日期:1981-01-01 00:00:00

  • Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: a population-based study.

    abstract:BACKGROUND/AIMS:People may have symptoms of multiple disorders at the same time. We aimed to determine prevalence and risk factors for overlaps between gastroesophageal reflux disease (GERD), dyspepsia and irritable bowel syndrome (IBS) in a Korean population. METHODS:A cross-sectional survey was performed on 1,688 ra...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000211715

    authors: Lee SY,Lee KJ,Kim SJ,Cho SW

    更新日期:2009-01-01 00:00:00

  • Characterization of the gastroprotective effects of N,N-diethyl-2-[4-(phenylmethyl)phenoxy]-ethanamine hydrochloride, a non-H1/non-H2 histamine antagonist.

    abstract::N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine HCl (DPPE) is an antihistamine with a unique profile of activity in the stomach. It is antisecretory and blocks the formation of experimental cold/stress- and ethanol-induced gastric lesions, as well as cysteamine-induced duodenal ulcers in a fashion more potent than o...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000200489

    authors: Glavin GB,Gerrard JM

    更新日期:1990-01-01 00:00:00

  • Transitional Care for Patients with Inflammatory Bowel Disease: Japanese Experience.

    abstract:BACKGROUND:Transition-related healthcare intervention has recently been receiving worldwide attention. Given the increasing incidence of pediatric inflammatory bowel disease (IBD) and its lifelong impact, transitional care has become an important issue. In Japan, guidelines to support the autonomy of IBD patients durin...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000510652

    authors: Kumagai H,Suzuki Y,Shimizu T

    更新日期:2021-01-01 00:00:00

  • Helicobacter pylori, peptic ulcer disease and inhibition of gastric acid secretion.

    abstract::Recent studies have been reviewed to establish the possible importance of the interaction between Helicobacter pylori infection and gastric acid secretion. H. pylori infection results in increased gastrin release, but this does not lead to gastric acid hypersecretion and gastrin normalizes after eradication of the inf...

    journal_title:Digestion

    pub_type: 杂志文章,评审

    doi:10.1159/000200908

    authors: Rune S

    更新日期:1992-01-01 00:00:00

  • Induction of gastric ornithine decarboxylase in early weaning rats.

    abstract:BACKGROUND/AIMS:Early weaning has been shown to induce intestinal ornithine decarboxylase (ODC) activities and cell proliferation in rats. No information is available about the effect of early weaning on ODC activity in the stomach. METHODS:Suckling rats were prematurely weaned on postnatal day 15 and followed through...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000051892

    authors: Lin CH,Lyons H,Seelbach MS,Tolia V,Vijesurier R

    更新日期:2001-01-01 00:00:00

  • Faecal characteristics and colonic intraluminal pressure in diverticular disease.

    abstract::Daily faecal calcium and magnesium outputs were inversely related to food-stimulated colonic intraluminal pressure in diverticular disease subjects. There was no relationship to sodium potassium and bile acid concentrations, nor to intestinal transit. ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198481

    authors: Eastwood MA,Smith AN,Mitchell WD,Pritchard JL

    更新日期:1980-01-01 00:00:00

  • Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.

    abstract::The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinom...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000197663

    authors: Lehmann FG,Kornacher J

    更新日期:1975-01-01 00:00:00

  • Long-Term Outcomes after Surgical Resection for Synchronous or Metachronous Hepatic and Pulmonary Colorectal Cancer Metastases.

    abstract:BACKGROUND/AIMS:At present, benefits of surgical resection and appropriate selection criteria in patients affected by both hepatic and pulmonary metastases of colorectal cancer (CRC) are under discussion. Our analysis focused on a surgical series of such patients and our final aim consisted in identifying potential pro...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000497223

    authors: Zizzo M,Galeone C,Braglia L,Ugoletti L,Siciliani A,Nachira D,Margaritora S,Pedrazzoli C,Paci M,Lococo F

    更新日期:2020-01-01 00:00:00

  • Cold and hot snare endoscopic techniques for removal of the Bravo pH monitoring capsule.

    abstract:BACKGROUND:Currently, use of the Bravo capsule is a very common method for evaluating the gastroesophageal reflux because it has the advantage of being an intraesophageal catheter-free system. However, endoscopic removal of the capsule is necessary when technical problems or severe discomfort are present. Most frequent...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000194945

    authors: de Hoyos A,Esparza EA,Loredo ML

    更新日期:2009-01-01 00:00:00

  • Glucagon, secretin and vasoactive intestinal polypeptide immunoreactivities in rat gut after jejuno-ileal bypass and resection.

    abstract::Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199226

    authors: Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

    更新日期:1985-01-01 00:00:00

  • Extensive small bowel resection in the rat: lack of effect on serum proteins.

    abstract::Rats were subjected to serial venesections 3 days prior to and then sequentially for 4 weeks after surgical removal of either the proximal or distal half of the small bowel. Total serum protein concentration and protein electrophoretic patterns were determined on these sera. Both sham-operated and unoperated animals s...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198408

    authors: Urban E,Ricks PM

    更新日期:1980-01-01 00:00:00

  • Effects of pirenzepine and atropine on amylase response to various secretagogues from the rat pancreatic acini.

    abstract::CCK-8, bombesin, secretin and urecholine added in various concentrations to the incubation medium of the dispersed pancreatic acini, obtained from rats, resulted in a dose-dependent stimulation of amylase secretion, the half-maximal response being achieved at 3 X 10(-12), 10(-10), 10(-7) and 10(-5) M, respectively. Pi...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199415

    authors: Jaworek J,Konturek SJ

    更新日期:1987-01-01 00:00:00

  • Mucin content in gallbladders with brown pigment stones or combination stones with a brown periphery.

    abstract:BACKGROUND/AIMS:Gallbladder mucus itself has been recognized to play an important role in gallstone development. Despite the diverse mechanisms of stone induction and the differences in stone composition, there is a quantitative increase in the epithelial mucus production period before stone formation. As brown pigment...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007572

    authors: Sheen PC,Lee KT,Liu YE

    更新日期:1998-11-01 00:00:00