Abstract:
:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/or dosage regimens have changed their placements in the medical management of UC. In addition, studies have shown that a number of novel therapeutic agents, designed to target specific mechanisms involved in the inflammatory cascade, have efficacy for the treatment of UC and they will have significant clinical impacts in the near future. A clear understanding of the proven and potential benefits of both the standard and emerging therapies will be required for the optimum individual care of patients with varied clinical presentations.
journal_name
Digestionjournal_title
Digestionauthors
Nakamura T,Nagahori M,Kanai T,Watanabe Mdoi
10.1159/000111486subject
Has Abstractpub_date
2008-01-01 00:00:00pages
36-41eissn
0012-2823issn
1421-9867pii
000111486journal_volume
77 Suppl 1pub_type
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