Acute and chronic effect of dietary cholic acid on colonic epithelial cell proliferation.

abstract：BACKGROUND/AIMS:We evaluated the effects of an antagonist of the thromboxane A2 receptor (ONO-NT-126) in an animal model of inflammatory bowel disease (IBD). METHODS:Colitis was induced by intracolonic instillation of trinitrobenzenesulfonic acid/ethanol in male Wistar rats. ONO-NT-126 or vehicle alone was administere...

journal_title：Digestion

authors： Taniguchi T,Tsukada H,Nakamura H,Kodama M,Fukuda K,Tominaga M,Seino Y

更新日期：1997-01-01 00:00:00

abstract：:The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

journal_title：Digestion

authors： Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The combined effects of nutrient malabsorption and adiposity on vitamin D status are unclear in pediatric malabsorption syndromes. AIM:To determine the relationship between adiposity and serum 25-hydroxyvitamin D (25(OH)D) in malabsorption disorders. METHODS:Prepubertal children of ages 3-12 with either la...

journal_title：Digestion

authors： Nwosu BU,Maranda L

更新日期：2015-01-01 00:00:00

abstract：:Serum retinol and serum carotene concentrations were determined over a 6-month period in 137 outpatients with Crohn's disease. Serum retinol measurements were within the reference range for all patients at each assessment period, while serum carotene levels were low in about one quarter of the patients. Of the 56 pati...

journal_title：Digestion

authors： Imes S,Pinchbeck B,Dinwoodie A,Walker K,Thomson AB

更新日期：1987-01-01 00:00:00

abstract：:Intact segments of rat ileum were stimulated in vitro by either electrical field stimulation (EFS) or cholinergic stimulation with carbachol, in the presence of absence of varying insulin concentrations (50, 100 and 200 microU/ml), and the contraction in the longitudinal axis was recorded. Insulin had no significant i...

journal_title：Digestion

authors： Allescher HD,Willis S,Schusdziarra V,Classen M

更新日期：1991-01-01 00:00:00

abstract：:Leucine absorption across the mechanically obstructed rat intestine was studied by in vivo and in vitro techniques. It varied between the early (after 2 h) and late (after 18 h) phases of the obstruction. During the early phase there was a reduction in mucosal uptake and in net absorption of the amino acid. At 18 h th...

journal_title：Digestion

authors： Hajjar JJ,Schwartz RG,Mirkin KR,Tomicic TK

更新日期：1982-01-01 00:00:00

abstract：:Malabsorption syndromes are commonly caused by pathological interferences of normal digestive processes. In the last several years major advances in the diagnosis and treatment of these syndromes has emerged. This review will focus on diseases in which the mucosal phase of the digestive process is predominately distur...

journal_title：Digestion

authors： Sun DF,Fang JY

更新日期：2006-01-01 00:00:00

abstract：:The activity of platelet-activating factor (PAF) acetylhydrolase in biopsy specimens of intestinal mucosa was compared in patients with Crohn's disease (n = 11) and controls (n = 6). In addition, PAF acetylhydrolase activity was determined in the plasma of Crohn patients (n = 30) and healthy subjects (n = 35). The act...

journal_title：Digestion

authors： Kald B,Smedh K,Olaison G,Sjödahl R,Tagesson C

更新日期：1996-11-01 00:00:00

abstract：:Glycoprotein and protein production of isolated pig gastric mucosal cells were determined by the incorporation of N-acetyl-[14C]D-glucosamine ([14C]GlcNAc) and [3H]L-leucine ([3H]Leu) into acid-insoluble macromolecules (AIM). In four cell fractions (F1-F4), obtained by counterflow centrifugation, specific [14C]GlcNAc ...

journal_title：Digestion

authors： Heim HK,Oestmann A,Thiele H,Sewing KF

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The exact etiology of irritable bowel syndrome (IBS) remains unclear. Curative treatment is not available and current treatment modalities are mainly directed against the predominant symptoms. There are a few studies reporting the beneficial effects of transcutaneous electrical stimulation in patients with c...

journal_title：Digestion

authors： Coban Ş,Akbal E,Köklü S,Köklü G,Ulaşlı MA,Erkeç S,Aktaş B,Yüksel O,Koçak E,Erdem HR

更新日期：2012-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：:The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar...

journal_title：Digestion

authors： Burroughs AK,Malagelada R

更新日期：1993-01-01 00:00:00

abstract：:We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

journal_title：Digestion

authors： Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Acotiamide, a prokinetic drug, is used to treat functional dyspepsia (FD), especially postprandial distress syndrome (PDS). However, a treatment for FD patients with PDS and/or epigastric pain syndrome (EPS) has not been established. We investigated the efficacy of famotidine in combination with acotiam...

journal_title：Digestion

authors： Hojo M,Nagahara A,Asaoka D,Takeda T,Izumi K,Matsumoto K,Ueyama H,Shimada Y,Matsumoto K,Nojiri S,Watanabe S

更新日期：2017-01-01 00:00:00

abstract：:Familial colorectal cancer (CRC) is heterogeneous. Screening recommendations do exist for individuals with a mild to moderate family history of CRC, with or without early age at onset. However, most attention has properly focused on the identification of individuals in whom a defined susceptibility gene mutation can b...

journal_title：Digestion

authors： Lynch PM

更新日期：2007-01-01 00:00:00

abstract：:Interdigestive motor activity has been studied extensively both in the human and canine small intestine. The more irregular postprandial pattern, however, has rarely been studied. In particular, physiological studies in humans are lacking. Thus it is unknown whether the physical state of a meal affects the duration of...

journal_title：Digestion

authors： v Schönfeld J,Evans DF,Goebell H,Wingate DL

更新日期：1997-01-01 00:00:00

abstract：:Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...

journal_title：Digestion

authors： Panda AP,Laughton JM,Elder JB,Gillespie IE

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:The pathogenesis of dyspeptic/reflux symptoms and the clinico-pathologic profile of affected patients are still poorly understood. To improve our knowledge in this field we carried out a systematic, comparative analysis of symptom profiles and histopathologic patterns of oesophagogastroduodenal mucosa i...

journal_title：Digestion

authors： Villani L,Trespi E,Fiocca R,Broglia F,Colla C,Luinetti O,Tinelli C,Solcia E

更新日期：1998-01-01 00:00:00

abstract：:The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...

journal_title：Digestion

authors： Gerbes AL,Hoermann R,Mann K,Jüngst D

更新日期：1996-01-01 00:00:00

abstract：:Rats were given 59Fe (28 micrograms) together with doses of 0, 2 and 200 micrograms of uroporphyrin III in paired observations. Absorption of 59Fe was determined by comparing whole body counts of the rats 30 min and 7 days after dosing. Prior treatment with 200 micrograms of uroporphyrin twice daily for 3 days was ass...

journal_title：Digestion

authors： Weaver GA,Franck CA,Harris MD,Peters T Jr

更新日期：1991-01-01 00:00:00

abstract：:The ratio of 6beta-hydroxycortisol to 17-hydroxycorticosteroids in the urine of 73 patients with liver disease, and 53 controls has been measured. The mean ratio was significantly greater in the liver disease group (p less than 0.001), this elevation being most marked among patients with liver metastases and patients ...

journal_title：Digestion

authors： Eade OE,Maddison A,Leonard PJ,Wright R

更新日期：1977-01-01 00:00:00

abstract：:The gastric acid and pepsin-stimulating activities of several C terminal fragments of non-sulphated human gastrin were investigated in the conscious cat prepared with cannulated gastric fistulae with a reproducible, continuous infusion method to construct dose-response curves. The gastric acid-stimulating activities w...

journal_title：Digestion

authors： Blair EL,Hirst BH,Lund PK,Reed JD,Sanders DJ,Shaw B

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Overt hepatic encephalopathy (HE) following insertion of a transjugular intrahepatic portosystemic shunt (TIPS) is a problem in some patients. In contrast to overt HE, minimal HE (MHE) following TIPS is studied to a limited degree only. We therefore evaluated the incidence of MHE in patients following TIPS i...

journal_title：Digestion

authors： Biecker E,Hausdörfer I,Grünhage F,Strunk H,Sauerbruch T

更新日期：2011-01-01 00:00:00

abstract：:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/o...

journal_title：Digestion

authors： Nakamura T,Nagahori M,Kanai T,Watanabe M

更新日期：2008-01-01 00:00:00

abstract：:By immunohistochemistry and double staining technique, almost complete coexistence of galanin-like immunoreactivity (GAL-LI) and vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) was demonstrated in submucosal ganglionic cells and mucosal nerve fibers of the porcine ileum. The release of the two neurope...

journal_title：Digestion

authors： Harling H,Messell T,Poulsen SS,Rasmussen TN,Holst JJ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:We have used the Zucker diabetic fatty (ZDF) rat to study the effects of type-2 diabetes and troglitazone on the small intestinal mucosal mass, sugar transporters and the peroxisomal proliferator-activated receptor, PPAR-gamma. METHODS:Age-matched ZDF and lean control (ZLC) rats were fed a standard cho...

journal_title：Digestion

authors： Corpe C,Sreenan S,Burant C

更新日期：2001-01-01 00:00:00

abstract：:A case of sporadic, histamine-producing gastric carcinoid with liver metastases is reported. The patient was treated with somatostatin analogue (octreotide) combined with cortisone and blockade of histamine receptors prior to surgery, which included subtotal gastrectomy, excision of lymph node metastases and superfici...

journal_title：Digestion

authors： Kölby L,Wängberg B,Ahlman H,Jansson S,Forssell-Aronsson E,Erickson JD,Nilsson O

更新日期：1998-01-01 00:00:00

abstract：:To assess the sensitivity, specificity and clinical value of prealbumin as liver test, prealbumin plasma levels were measured in 100 patients with liver disease and in 65 patients without clinical evidence of liver impairment. The sensitivity of prealbuminemia was higher than that of albumin, pseudocholinesterase, apo...

journal_title：Digestion

authors： Rondana M,Milani L,Merkel C,Caregaro L,Gatta A

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:The authors reported that the repair of submucosal tissue is important in ulcer healing. The kinetics of fibroblasts have not been well known in gastric ulcer healing. The effect of subcutaneous administration of indomethacin (1 mg/kg) to submucosal tissue was also examined. METHOD:Immunohistological stainin...

journal_title：Digestion

authors： Hirose Y,Goto H,Arisawa T,Hase S,Niwa Y,Hayakawa T,Asai J,Tsukamoto Y

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to compare the accuracy of magnifying endoscopy with narrow band imaging for the diagnosis of depth of invasion by Japan Esophageal Society (JES) classification and inter- and intraobserver agreement of JES intrapapillary capillary loop (IPCL) classification. METHODS:It was a r...

journal_title：Digestion

authors： Mizumoto T,Hiyama T,Quach DT,Sanomura Y,Urabe Y,Oka S,Arihiro K,Tanaka S,Chayama K

更新日期：2018-01-01 00:00:00