Modulation of growth of human gastric enterochromaffin-like cells.

abstract：:Since biguanides are known to inhibit hexose and amino acid absorption in vivo and in vitro as well as vitamin B12 absorption the effect of phenethylbiguanide on taurocholate (TC) and water absorption was measured in rat ileum in vivo. Phenethylbiguanide exhibited a time-dependent inhibitory effect on TC- and water ab...

journal_title：Digestion

authors： Caspary WF,Lücke H

更新日期：1975-01-01 00:00:00

abstract：:Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity w...

journal_title：Digestion

authors： Shaw B,Wright CL

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND AIM:Sonic hedgehog (Shh) is a morphogen involved in the homeostasis of the gastric fundic glands. Alterations of gastric mucosal Shh expression after eradication of Helicobacter pylori were examined. METHOD:Mongolian gerbils were inoculated with H. pylori at the age of 5 weeks. H. pylori eradication was...

journal_title：Digestion

authors： Nishizawa T,Suzuki H,Nakagawa I,Minegishi Y,Masaoka T,Iwasaki E,Hibi T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:In this report, we aimed to investigate the distribution and characterization of biomarker-immunolabeled ductal epithelium in advanced pancreatic ductal adenocarcinoma (PDAC). DESIGN:Eighteen patients with PDAC were medically diagnosed prior to being treated periodically. All clinical records were coll...

journal_title：Digestion

authors： Zhou R,Xu X,Liu M,Wu X,Li R

更新日期：2019-01-01 00:00:00

abstract：:Buffalo strain male and female rats were given methylazoxymethanol acetate (20% solution) intraperitoneally 20 mg/kg body weight weekly for 9 weeks, and killed 27 weeks later. Carcinomas of the large intestine, predominantly in the descending colon, developed in some of the rats. The incidence was higher in male than ...

journal_title：Digestion

authors： Reuber MD

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND/AIMS:Autoimmune gastritis (AIG) may predispose to gastric carcinoid tumors or adenocarcinomas and may also cause unexplained iron and/or vitamin B(12) deficiency. The aims of this study were to explore clinical manifestations, endoscopic findings and laboratory features of patients with AIG. METHODS:109 pat...

journal_title：Digestion

authors： Soykan I,Yakut M,Keskin O,Bektaş M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) results from an aberrant immune response to the indigenous intestinal flora in genetically susceptible hosts. Therefore, the study of candidate genes involved in host pathogen interactions is of key interest. METHODS:In this two-center, retrospective German and Hungarian coh...

journal_title：Digestion

authors： Baumgart DC,Buning C,Geerdts L,Schmidt HH,Genschel J,Fiedler T,Gentz E,Molnar T,Nagy F,Lonovics J,Lochs H,Wiedenmann B,Nickel R,Witt H,Dignass A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy in laparoscopic surgery is radical, similar to that of open gastrectomy for patients with early gastric ca...

journal_title：Digestion

authors： Hiramatsu Y,Takeuchi H,Goto O,Kikuchi H,Kitagawa Y

更新日期：2019-01-01 00:00:00

abstract：:The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

journal_title：Digestion

authors： Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

更新日期：1989-01-01 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00

abstract：:Rectal biopsies were maintained in organ culture over a 24-hour culture period, with good preservation of histological architecture. A filtrate containing Clostridium difficile toxin significantly inhibited the rise in epithelial alkaline phosphatase activity normally seen during culture. This effect was abolished by ...

journal_title：Digestion

authors： Allan A,Jewell DP

更新日期：1985-01-01 00:00:00

abstract：:Interdigestive motor activity has been studied extensively both in the human and canine small intestine. The more irregular postprandial pattern, however, has rarely been studied. In particular, physiological studies in humans are lacking. Thus it is unknown whether the physical state of a meal affects the duration of...

journal_title：Digestion

authors： v Schönfeld J,Evans DF,Goebell H,Wingate DL

更新日期：1997-01-01 00:00:00

abstract：:The secretion of pancreatic polypeptide (PP) seems to be controlled by vagal cholinergic mechanisms, since both vagotomy and atropine significantly inhibit the PP response to food intake, sham feeding or insulin hypoglycaemia. In the present study, we examined the PP response to a meal after orthotopic autotransplanta...

journal_title：Digestion

authors： Köhler H,Becker HD

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND/AIM:Diarrhoea in collagenous colitis has been considered as secretory though the pathophysiology has been studied thoroughly in only a few patients. The result of fasting is one way to distinguish between secretory and osmotic diarrhoea. Our aim was to investigate the effect of fasting on diarrhoea in collag...

journal_title：Digestion

authors： Bohr J,Järnerot G,Tysk C,Jones I,Eriksson S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Transition-related healthcare intervention has recently been receiving worldwide attention. Given the increasing incidence of pediatric inflammatory bowel disease (IBD) and its lifelong impact, transitional care has become an important issue. In Japan, guidelines to support the autonomy of IBD patients durin...

journal_title：Digestion

authors： Kumagai H,Suzuki Y,Shimizu T

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Multiple Lugol-voiding lesions (LVLs) in the esophagus increase the risk of synchronous and metachronous development of esophageal squamous cell carcinoma (ESCC). Chemoradiotherapy (CRT) following endoscopic submucosal dissection (ESD) may reduce the incidence of metachronous ESCC, but few studies have inv...

journal_title：Digestion

authors： Suzuki Y,Kikuchi D,Hoteya S,Okamura T,Ochiai Y,Hayasaka J,Dan N,Mitsunaga Y,Tanaka M,Odagiri H,Nomura K,Yamashita S,Matsui A,Iizuka T

更新日期：2020-09-29 00:00:00

abstract：:The gastric acid and pepsin-stimulating activities of several C terminal fragments of non-sulphated human gastrin were investigated in the conscious cat prepared with cannulated gastric fistulae with a reproducible, continuous infusion method to construct dose-response curves. The gastric acid-stimulating activities w...

journal_title：Digestion

authors： Blair EL,Hirst BH,Lund PK,Reed JD,Sanders DJ,Shaw B

更新日期：1980-01-01 00:00:00

abstract：:Differential absorption of D-xylose and 3-O-methyl-D-glucose, and unmediated intestinal permeation of lactulose and L-rhamnose has been investigated in 14 patients with diarrhoea following tropical exposure and in 16 healthy control subjects. Five had malabsorption of fat, D-xylose and B12 ('tropical malabsorption' (T...

journal_title：Digestion

authors： Cook GC,Menzies IS

更新日期：1986-01-01 00:00:00

abstract：:Fructus has motivation effect on gastrointestinal tract. Hesperidin is extracts of Fructus, and we attempted to prove its effects on improving the gastrointestinal transmission function and determine the possible mechanisms by a loperamide-induced slow transit constipation (STC) model. Constipation phenotypes were mea...

journal_title：Digestion

authors： Wu M,Li Y,Gu Y

更新日期：2020-01-01 00:00:00

abstract：:The intestinal phase of enterohepatic circulation, such as site and state of bile acid absorption, along the length of the intestinal tract has been speculated but not directly quantitated. In order to gain insight into the actual state of intestinal absorption of bile acid, the bile acid composition of portal blood f...

journal_title：Digestion

authors： Fujii T,Yanagisawa J,Nakayama F

更新日期：1988-01-01 00:00:00

abstract：:The esophageal epithelium maintains its integrity by both structural and functional epithelial defenses. Structural components are cell membranes and intercellular junctional complexes. Functional components are cellular defenses against acidification consisting of intracellular buffering by basic proteins and bicarbo...

journal_title：Digestion

authors： Tobey NA

更新日期：1995-01-01 00:00:00

abstract：:The activity of platelet-activating factor (PAF) acetylhydrolase in biopsy specimens of intestinal mucosa was compared in patients with Crohn's disease (n = 11) and controls (n = 6). In addition, PAF acetylhydrolase activity was determined in the plasma of Crohn patients (n = 30) and healthy subjects (n = 35). The act...

journal_title：Digestion

authors： Kald B,Smedh K,Olaison G,Sjödahl R,Tagesson C

更新日期：1996-11-01 00:00:00

abstract：:We studied the functional coupling between antral somatostatin and gastrin cells in pigs using isolated perfused preparations of the antrum with intact supply of the vagus nerves. Luminal acidification significantly inhibited gastrin secretion to 61 +/- 3% of basal secretion and increased somatostatin output 9-fold. I...

journal_title：Digestion

authors： Holst JJ,Orskov C,Seier-Poulsen S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:As opposed to regular C-reactive protein (CRP) assays, the introduction of high-sensitivity ones has enabled us to detect low grade inflammation in patients with inflammatory bowel disease (IBD). We addressed the subject of the degree of correlation between the concentration of high-sensitivity CRP (hs-...

journal_title：Digestion

authors： Zilberman L,Maharshak N,Arbel Y,Rogowski O,Rozenblat M,Shapira I,Berliner S,Arber N,Dotan I

更新日期：2006-01-01 00:00:00

abstract：:Retractile mesenteritis is an extremely rare disease characterised by a non-specific inflammatory and fibrotic process of the mesenteric adipose tissue, which is usually accompanied by pain and a variety of other abdominal symptoms. We describe here the case of a patient with retractile mesenteritis presenting with pr...

journal_title：Digestion

authors： Papadaki HA,Kouroumalis EA,Stefanaki K,Roussomoustakaki M,Daskalogiannaki ME,Reppa D,Eliopoulos GD

更新日期：2000-01-01 00:00:00

abstract：:The distribution of tryptophan hydroxylase, the rate-limiting enzyme in the biosynthesis of serotonin, was investigated immunohistochemically in various organs of the gastrointestinal tract and compared with that of neuroendocrine markers. While immunoreactivity for serotonin and chromogranin A was restricted to enter...

journal_title：Digestion

authors： Meyer T,Brinck U

更新日期：1999-01-01 00:00:00

abstract：:Non-erosive reflux disease (NERD) has assumed increasing prominence in studies of gastroesophageal reflux disease (GERD), but it remains a challenge to define NERD precisely and to define its place in the investigation and treatment of GERD. Most simply, NERD may be defined as GERD in an individual who has no evidence...

journal_title：Digestion

authors： Armstrong D

更新日期：2008-01-01 00:00:00

abstract：:The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...

journal_title：Digestion

authors： Pezzilli R,Billi P,Platè L,Bongiovanni F,Morselli Labate AM,Miglioli M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) of early esophageal cancer (EC) is becoming more widespread. Post-ESD coagulation syndrome (CS) has been proposed as temporary inflammatory signs that occur during the post-ESD period caused by transmural thermal injury by electrocoagulation. This retrospective study ai...

journal_title：Digestion

authors： Sakai M,Sohda M,Saito H,Ubukata Y,Nakazawa N,Kuriyama K,Hara K,Sano A,Ogata K,Yokobori T,Kuwano H,Shirabe K,Saeki H

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Previous research has shown that infliximab (IFX) is effective in the management of moderate to severe active ulcerative colitis (UC). Latin American studies are lacking. AIM:To evaluate the efficacy of IFX treatment (including corticosteroid withdrawal, complete mucosal healing, colectomy and hospitalizati...

journal_title：Digestion

authors： Juliao F,Marquez J,Aristizabal N,Yepes C,Zuleta J,Gisbert JP

更新日期：2013-01-01 00:00:00