Effect of gastrin on fasting and postprandial plasma GIP release in man.

abstract：BACKGROUND/AIMS:Combined pH-metry/multichannel intraluminal impedance (pH/MII) measurement enables to measure gastroesophageal reflux despite ongoing proton pump inhibitor therapy. The aim of our study was to evaluate the influence of an escalating medical anti-reflux therapy with 40 mg esomeprazole, 80 mg esomeprazole...

journal_title：Digestion

authors： Bajbouj M,Becker V,Phillip V,Wilhelm D,Schmid RM,Meining A

更新日期：2009-01-01 00:00:00

abstract：:Discussion over the role of enzyme therapy in patients with acute pancreatitis is based upon theoretical considerations rather than hard data. In this respect, it differs little from most other treatments used in the management of acute pancreatitis, although, in the case of enzyme treatment, the lack of data results ...

journal_title：Digestion

authors： McMahon MJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND AIM:The medical treatment of rheumatoid arthritis (RA) includes nonsteroidal anti-inflammatory drugs (NSAIDs), low-dose corticosteroids, and disease-modifying antirheumatic drugs (DMARDs). We evaluated the incidence of small bowel injury in RA patients who were taking anti-RA drugs with or without concom...

journal_title：Digestion

authors： Sugimori S,Watanabe T,Tabuchi M,Kameda N,Machida H,Okazaki H,Tanigawa T,Yamagami H,Shiba M,Watanabe K,Tominaga K,Fujiwara Y,Oshitani N,Koike T,Higuchi K,Arakawa T

更新日期：2008-01-01 00:00:00

abstract：:Intact segments of rat ileum were stimulated in vitro by either electrical field stimulation (EFS) or cholinergic stimulation with carbachol, in the presence of absence of varying insulin concentrations (50, 100 and 200 microU/ml), and the contraction in the longitudinal axis was recorded. Insulin had no significant i...

journal_title：Digestion

authors： Allescher HD,Willis S,Schusdziarra V,Classen M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:To identify the number and potential causes of unnecessary diagnostic procedures in a cohort of patients with autoimmune pancreatitis (AIP). METHODS:All AIP cases at our centre between April 2006 and April 2013 were collected and followed up. Diagnosis was established by the International Consensus Dia...

journal_title：Digestion

authors： Manser CN,Gubler C,Müllhaupt B,Bauerfeind P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:Sonic hedgehog (Shh) is a morphogen involved in the homeostasis of the gastric fundic glands. Alterations of gastric mucosal Shh expression after eradication of Helicobacter pylori were examined. METHOD:Mongolian gerbils were inoculated with H. pylori at the age of 5 weeks. H. pylori eradication was...

journal_title：Digestion

authors： Nishizawa T,Suzuki H,Nakagawa I,Minegishi Y,Masaoka T,Iwasaki E,Hibi T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Several earlier studies on factors predicting the long-term outcome of ulcerative colitis only encompassed treatment failure for one severe episode, or suffered from a lack of multivariate analyses. We aimed to identify factors assessable at diagnosis or after the first induction therapy which predicted...

journal_title：Digestion

authors： Shiga H,Takagi S,Inoue R,Kinouchi Y,Ohkubo T,Takahashi S,Negoro K,Yokoyama H,Kato S,Fukushima K,Hiwatashi N,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/o...

journal_title：Digestion

authors： Nakamura T,Nagahori M,Kanai T,Watanabe M

更新日期：2008-01-01 00:00:00

abstract：:Net fluid movement and mucosal 14C-erythritol clearance were measured in ligated colonic loops of the rat in vivo. The diphenolic laxatives, oxyphenisatin and bisacodyl, dose-dependently inhibited net fluid absorption or caused secretion, both increased the 14C-erythritol clearance. Pretreatment with the adenylate cyc...

journal_title：Digestion

authors： Farack UM,Nell G

更新日期：1984-01-01 00:00:00

abstract：:Gastric actions of Nw-nitro-1-arginine methyl ester (L-NAME) were investigated in rats, as this agent is a reliable nitric oxide synthase inhibitor L-NAME solutions were placed in subcutaneous osmotic minipumps which continuously released L-NAME at 0.1, 1.0, 10, or 40 mg/kg/day. L-NAME dose and time-dependently enhanc...

journal_title：Digestion

authors： Qiu BS,Pfeiffer CJ,Cho CH

更新日期：1996-01-01 00:00:00

abstract：:Interdigestive motor activity has been studied extensively both in the human and canine small intestine. The more irregular postprandial pattern, however, has rarely been studied. In particular, physiological studies in humans are lacking. Thus it is unknown whether the physical state of a meal affects the duration of...

journal_title：Digestion

authors： v Schönfeld J,Evans DF,Goebell H,Wingate DL

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIM:Over the past 15 years, there were considerable changes in factors associated with the development and treatment of upper gastrointestinal symptoms, of which the introduction of proton pump inhibitors and Helicobacter pylori eradication in guidelines for treatment of patients with dyspepsia are the most ...

journal_title：Digestion

authors： van Kerkhoven LA,van Rijswijck SJ,van Rossum LG,Laheij RJ,Witteman EM,Tan AC,Jansen JB

更新日期：2007-01-01 00:00:00

abstract：:An improved GLC method was employed to study individual serum bile acids in 14 control subjects after a 12-hour fast followed by a standard fatty meal. Peripheral venous blood samples were obtained at 15-min intervals for up to 2 h in 7 subjects, and 4 h in 2 subjects. The fasting total bile acids, and cholic:chenodeo...

journal_title：Digestion

authors： Pennington CR,Ross PE,Bouchier IA

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Leptin, a product of the ob gene controlling food intake, has recently been detected in the stomach and shown to be released by cholecystokinin (CCK) and to induce gastroprotection against various noxious agents, but it is not known whether centrally applied leptin influences gastric secretion and mucosal in...

journal_title：Digestion

authors： Brzozowski T,Konturek PC,Konturek SJ,Pierzchalski P,Bielanski W,Pajdo R,Drozdowicz D,Kwiecień S,Hahn EG

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Leptin is a pleiotropic hormone that is involved in the regulation of food intake and body weight. Recent findings demonstrated that leptin receptors are present in the pancreas but the involvement of leptin in pancreatitis remains unknown. The aim of the present study was: (1) to assess plasma leptin levels...

journal_title：Digestion

authors： Konturek PC,Jaworek J,Maniatoglou A,Bonior J,Meixner H,Konturek SJ,Hahn EG

更新日期：2002-01-01 00:00:00

abstract：:The luminal mucus layer of the rat's small intestine was separated from the mucosa by filling the lumen with agar jelly. When the rats were fasted overnight and given 59Fe or 65Zn by stomach tube the mucus isolated by this technique contained more isotope and more sialic acid than fed controls, and more of the isotope...

journal_title：Digestion

authors： Quarterman J

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND/AIMS:Grading gastric mucosal atrophy in antrum biopsy specimens remains a controversial subject because of limitations in interobserver agreement. We previously described a reliable, quantitative method for grading atrophy of the corpus mucosa with excellent reproducibility and good correlation with the Sydn...

journal_title：Digestion

authors： van Grieken NC,Meijer GA,Kale I,Bloemena E,Lindeman J,Offerhaus GJ,Meuwissen SG,Baak JP,Kuipers EJ

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Validity of the lactulose breath test (LBT) to diagnose small intestinal bacterial overgrowth (SIBO) has been questioned. Therefore, a study was planned to compare LBT with glucose breath test (GBT) to diagnose SIBO in irritable bowel syndrome (IBS) patients and controls. METHODS:175 diarrhea-predo...

journal_title：Digestion

authors： Rana SV,Sharma S,Kaur J,Sinha SK,Singh K

更新日期：2012-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：:One to four months after implantation of a gastric fistula, a circadian rhythm in gastric acidity could be demonstrated by use of the intragastric 24-hour pH-metry in dogs with the gastric fistula protruding on the left side of the upper abdomen. This circadian rhythm was found to be fully developed within 3 years, an...

journal_title：Digestion

authors： Postius S,Bräuer U

更新日期：1995-01-01 00:00:00

abstract：:This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

journal_title：Digestion

authors： Raul F,Galluser M,Doffoel M

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Determining the depth of invasion is important when considering therapeutic strategies for early gastric cancer (EGC). We determined the effects of learning the non-extension sign, that is, an index of T1b2 in EGC, on identifying its depth of invasion. METHODS:Endoscopic images of 40 EGC cases (20 showing p...

journal_title：Digestion

authors： Takeda T,So S,Sakurai T,Nakamura S,Yoshikawa I,Yada S,Itaba S,Yamagata H,Akiho H,Takatsu N,Wada Y,Ohtsu K,Nagahama T,Yao K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Roux-en-Y gastric bypass surgery is the most common bariatric surgery worldwide. We have described thiamine deficiency in patients with small intestinal bacterial overgrowth after gastric bypass. We hypothesized that symptoms of thiamine deficiency are common after gastric bypass. The aims of this study...

journal_title：Digestion

authors： Shah HN,Bal BS,Finelli FC,Koch TR

更新日期：2013-01-01 00:00:00

abstract：:We consider the multiple interacting factors which lead to the proliferation of human gastric enterochromaffin-like (ECL) cells, and control of this proliferation by somatostatin and its analogues. Somatostatin receptors occur in human fundic mucosa, and octreotide can be considered a useful therapeutic tool to contro...

journal_title：Digestion

authors： Delle Fave G,Annibale B

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to compare the accuracy of magnifying endoscopy with narrow band imaging for the diagnosis of depth of invasion by Japan Esophageal Society (JES) classification and inter- and intraobserver agreement of JES intrapapillary capillary loop (IPCL) classification. METHODS:It was a r...

journal_title：Digestion

authors： Mizumoto T,Hiyama T,Quach DT,Sanomura Y,Urabe Y,Oka S,Arihiro K,Tanaka S,Chayama K

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Combinations of antitumor necrosis factor alpha (TNFα) and immunomodulators may be indicated in high-risk inflammatory bowel disease patients. Our aims were to compare disease course between children that did and did not step down to anti-TNFα monotherapy and to define risk factors for complicated disease cou...

journal_title：Digestion

authors： Yerushalmy-Feler A,Moran-Lev H,Galai T,Cohen S

更新日期：2020-01-01 00:00:00

abstract：:L-Amino acid solution given intravenously in Heidenhain pouch dogs resulted in marked changes of both basal and pentagastrin-stimulated gastric secretions. During a 1-hour amino acid infusion, a significant augmentation of pentagastrin-induced secretion was observed. A significant increase of secretion during amino ac...

journal_title：Digestion

authors： Bilski R,Kowalewski K,Secord DC

更新日期：1978-01-01 00:00:00

abstract：:Cell renewal in the duodenal mucosa of Mastomys was studied by autoradiography 1 and 24 h after intraperitoneal injection of tritiated thymidine. Non-specific duodenitis and duodenal ulceration were produced with a continuous infusion of histamine. Mucosal renewal in the duodenum of 30 control Mastomys was compared wi...

journal_title：Digestion

authors： Smedley FH,Rimmer J,Samanidis A,Wastell C

更新日期：1990-01-01 00:00:00

abstract：:Rats were given 59Fe (28 micrograms) together with doses of 0, 2 and 200 micrograms of uroporphyrin III in paired observations. Absorption of 59Fe was determined by comparing whole body counts of the rats 30 min and 7 days after dosing. Prior treatment with 200 micrograms of uroporphyrin twice daily for 3 days was ass...

journal_title：Digestion

authors： Weaver GA,Franck CA,Harris MD,Peters T Jr

更新日期：1991-01-01 00:00:00

abstract：:A young Indian man presented in England with a 6-month history of diarrhoea which started just before leaving India. He was found to have tropical enteropathy and H. nana infestation, but while the infestation and symptoms disappeared with antihelminthic treatment, the tropical enteropathy persisted. Hymenolepiasis is...

journal_title：Digestion

authors： Cooper BT,Hodgson HJ,Chadwick VS

更新日期：1981-01-01 00:00:00