Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils.

abstract：:Familial colorectal cancer (CRC) is heterogeneous. Screening recommendations do exist for individuals with a mild to moderate family history of CRC, with or without early age at onset. However, most attention has properly focused on the identification of individuals in whom a defined susceptibility gene mutation can b...

journal_title：Digestion

authors： Lynch PM

更新日期：2007-01-01 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：:Indicators of net water movement are used in a variety of intestinal transport studies. Such indicators should be virtually unabsorbed under study conditions. The effects of stimuli that alter intestinal mass on indicator recovery have not been examined. We used the male albino rat to study the effects of food restric...

journal_title：Digestion

authors： Miller DL,Schedl HP,Bouska J,Phillips SF

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...

journal_title：Digestion

authors： Takeshita E,Sakata Y,Hara M,Akutagawa K,Sakata N,Endo H,Ohyama T,Matsunaga K,Yoshioka T,Kawakubo H,Tanaka Y,Shirai S,Ito Y,Tsuruoka N,Iwakiri R,Kusano M,Fujimoto K

更新日期：2016-01-01 00:00:00

abstract：:The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during i...

journal_title：Digestion

authors： Laskus T,Radkowski M,Slusarczyk J,Cianciara J

更新日期：1992-01-01 00:00:00

abstract：:Gastric actions of Nw-nitro-1-arginine methyl ester (L-NAME) were investigated in rats, as this agent is a reliable nitric oxide synthase inhibitor L-NAME solutions were placed in subcutaneous osmotic minipumps which continuously released L-NAME at 0.1, 1.0, 10, or 40 mg/kg/day. L-NAME dose and time-dependently enhanc...

journal_title：Digestion

authors： Qiu BS,Pfeiffer CJ,Cho CH

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：:We describe a patient with relapses of Clostridium difficile cytotoxin-positive pseudomembranous colitis (PMC) after treatment with vancomycin, a course of metronidazole and a trial of bacitracin. She remains free of disease after a prolonged course of cholestyramine. We suggest there may be a role for anion-exchange ...

journal_title：Digestion

authors： Kunimoto D,Thomson AB

更新日期：1986-01-01 00:00:00

abstract：:A 3 years evolution with amyloid involvement, primarily of the liver, in a patient is described. This led to intrahepatic cholestasis and to portal hypertension with esophageal varices. ...

journal_title：Digestion

authors： Melkebeke P,Vandepitte J,Hannon R,Fevery J

更新日期：1980-01-01 00:00:00

abstract：:Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients. However, because reflux oesophagitis relapses rapidly when short-term treatment is dis...

journal_title：Digestion

authors： Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：:Intact segments of rat ileum were stimulated in vitro by either electrical field stimulation (EFS) or cholinergic stimulation with carbachol, in the presence of absence of varying insulin concentrations (50, 100 and 200 microU/ml), and the contraction in the longitudinal axis was recorded. Insulin had no significant i...

journal_title：Digestion

authors： Allescher HD,Willis S,Schusdziarra V,Classen M

更新日期：1991-01-01 00:00:00

abstract：:We conducted a retrospective analysis to evaluate the risk factors associated with the occurrence of acute hepatic failure following transcatheter arterial embolization (TAE) for hepatocellular carcinoma. From 1984 to 1993 we performed a total of 623 embolization procedures in 369 patients with both hepatocellular car...

journal_title：Digestion

authors： Katsushima S,Inokuma T,Oi H,Okamura J,Higashi T,Takeuchi R,Hidaka A,Shigeno C,Iida Y,Konishi J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The safety of carbon dioxide (CO(2)) insufflation has not been fully established for esophageal and gastric endoscopic submucosal dissection (ESD) under deep sedation, because CO(2) retention is not only caused by CO(2) insufflation but also by the sedation level and the patient's respiratory status...

journal_title：Digestion

authors： Takano A,Kobayashi M,Takeuchi M,Hashimoto S,Mizuno K,Narisawa R,Aoyagi Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Fecal lactoferrin has been introduced as a useful tool for the diagnosis and monitoring of inflammatory bowel disease (IBD). The aim of this study was to assess if fecal lactoferrin can be employed to predict or estimate the effect of granulocyte and monocyte adsorptive apheresis (GMA) in ulcerative colitis ...

journal_title：Digestion

authors： Hashiguchi K,Takeshima F,Akazawa Y,Matsushima K,Minami H,Machida H,Yamaguchi N,Shiozawa K,Ohba K,Ohnita K,Ichikawa T,Isomoto H,Nakao K

更新日期：2015-01-01 00:00:00

abstract：:This study was designed to compare the influence of omeprazole, a potent inhibitor of H+/K+-ATP-ase involved in the final step of H+ secretion and prostaglandin (PG) I2 on the formation of gastric mucosal lesions induced by absolute ethanol or acidified aspirin (ASA). Omeprazole given intragastrically in both inhibito...

journal_title：Digestion

authors： Konturek SJ,Brzozowski T,Radecki T

更新日期：1983-01-01 00:00:00

abstract：:The ratio of 6beta-hydroxycortisol to 17-hydroxycorticosteroids in the urine of 73 patients with liver disease, and 53 controls has been measured. The mean ratio was significantly greater in the liver disease group (p less than 0.001), this elevation being most marked among patients with liver metastases and patients ...

journal_title：Digestion

authors： Eade OE,Maddison A,Leonard PJ,Wright R

更新日期：1977-01-01 00:00:00

abstract：:To assess the sensitivity, specificity and clinical value of prealbumin as liver test, prealbumin plasma levels were measured in 100 patients with liver disease and in 65 patients without clinical evidence of liver impairment. The sensitivity of prealbuminemia was higher than that of albumin, pseudocholinesterase, apo...

journal_title：Digestion

authors： Rondana M,Milani L,Merkel C,Caregaro L,Gatta A

更新日期：1987-01-01 00:00:00

abstract：:The incidence of steatorrhea is said to be lower and its grade milder in Japanese because their fat intake is lower than that of Europeans and Americans. Failure to take this into account creates difficulties when attempting to compare data on pancreatic exocrine insufficiency in different countries. The authors exami...

journal_title：Digestion

authors： Nakamura T,Tando Y,Yamada N,Watanabe T,Ogawa Y,Kaji A,Imamura K,Kikuchi H,Suda T

更新日期：1999-01-01 00:00:00

abstract：:The current therapy of choice for all Helicobacter pylori-associated ulcer disease is eradication therapy. Although adequate therapeutic regimens are currently available, often still ineffective therapies are tried. Cure of the infection essentially eliminates the ulcer diathesis. Cure of the infection is especially i...

journal_title：Digestion

authors： Tytgat GN

更新日期：1998-08-01 00:00:00

abstract：:Leukocyte infiltration in the pancreas is involved in the aggravation of acute pancreatitis from edematous phase into necrotic change, and mild disease into severe disease; however, the mechanism responsible for leukocyte accumulation is not fully understood. This study was designed to clarify the mechanism underlying...

journal_title：Digestion

authors： Yamauchi J,Sunamura M,Shibuya K,Takeda K,Kobari M,Matsuno S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) is a chronic immune-mediated disorder of the gastrointestinal tract. The pathophysiological understanding of this disease is limited and no curative therapy is available so far. Therefore, most patients require long-lasting or even life-long immunosuppressive therapies for the suppressio...

journal_title：Digestion

authors： Vetter M,Neurath MF

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:The incidence of early-onset inflammatory bowel disease is increasing in Japan. OBJECTIVE:This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease. METHODS:This prospective survey evaluated the data of 43 patients aged <8 years who were diagnosed with inflammatory ...

journal_title：Digestion

authors： Kudo T,Fujii T,Maisawa SI,Sasaki M,Uchida K,Ida S,Kagimoto S,Yoden A,Shimizu T

更新日期：2020-05-18 00:00:00

abstract：:Recent studies have demonstrated the presence of both CCKA and CCKB receptors on dog and guinea pig pancreas. Although CCKA receptors are implicated in enzymatic secretion, biological effects of CCKB receptors are still unknown. We have previously found that a rat acinar pancreatic cell line (AR4-2J) possesses both re...

journal_title：Digestion

authors： Seva C,De Vries L,Scemama JL,Sarfati P,Nicolet TG,Pradayrol L,Vaysse N

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Symptoms caused by chronic pancreatitis (CP) are common but often elusive hampering therapeutic decisions. Though correlations of morphologic findings in imaging and clinical appearance remain vague. We aimed in investigating whether a distinct combination of clinical parameters can better define the extent ...

journal_title：Digestion

authors： Perkhofer L,Besold T,Schmidberger J,Seufferlein T,Hann A,Müller M,Kleger A

更新日期：2020-02-11 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00

abstract：:The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alp...

journal_title：Digestion

authors： Skov Olsen P,Kirkegaard P,Rasmussen T,Magid E,Poulsen SS,Nexø E

更新日期：1988-01-01 00:00:00

abstract：:Lithium is a cation which has central nervous system effects and is able to interfere with both the release and action of polypeptide hormones. We examined its effect on basal and stimulated plasma gastrin and pancreatic polypeptide (PP) levels in 4 dogs with chronic gastric fistulas. Gastrin and PP release were stimu...

journal_title：Digestion

authors： Modlin IM,Ehrlich BE,Lamers CB,Diamond JM,Walsh JH

更新日期：1981-01-01 00:00:00

abstract：:In 1905, John Edkins (1863-1940) undertook the studies of gastrin that have subsequently formed the basis for a century of investigation into the physiological basis of acid secretion and led to the elucidation of a variety of acid-suppressive pharmacological agents that have revolutionized the management of acid pept...

journal_title：Digestion

authors： Modlin IM,Sachs G,Wright N,Kidd M

更新日期：2005-01-01 00:00:00

abstract：:Non-erosive reflux disease (NERD) has assumed increasing prominence in studies of gastroesophageal reflux disease (GERD), but it remains a challenge to define NERD precisely and to define its place in the investigation and treatment of GERD. Most simply, NERD may be defined as GERD in an individual who has no evidence...

journal_title：Digestion

authors： Armstrong D

更新日期：2008-01-01 00:00:00

abstract：:Previous studies suggested that gastrin-releasing peptide (a neuropeptide found in rat oxyntic mucosa) and oxyntomodulin (a glucagon-containing peptide of mammalian gut) could directly affect the acid secretion of the parietal cells. We therefore studied their effect on gastric acid production in vitro by measuring [1...

journal_title：Digestion

authors： Gehl J,Jeppesen JL,Poulsen SS,Holst JJ

更新日期：1988-01-01 00:00:00