Omeprazole in the short-term treatment of reflux oesophagitis.

abstract：BACKGROUND:Although pain is the most feared part of the terminal life of many patients with cancer, the intensity and the quality of the pain is all too often only scantly described. METHOD:The quality and quantity of pain were prospectively registered by five variables, including a visual analogue scale (VAS), in 46 ...

journal_title：Digestion

authors： Grahm AL,Andrén-Sandberg A

更新日期：1997-01-01 00:00:00

abstract：:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/o...

journal_title：Digestion

authors： Nakamura T,Nagahori M,Kanai T,Watanabe M

更新日期：2008-01-01 00:00:00

abstract：:Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity w...

journal_title：Digestion

authors： Shaw B,Wright CL

更新日期：1976-01-01 00:00:00

abstract：:From questioning 16,939 South African pupils of 16-18 years, in 56 high schools, mean prevalences of appendicectomies in representative segments of ethnic groups were found to be: rural Blacks 0.6%; urban Blacks 0.7%; Indians, 2.9%; Coloureds (Eur-African-Malay), 1.7%; Whites, 10.5%. Percentages in the sexes were simi...

journal_title：Digestion

authors： Walker AR,Walker BF,Duvenhage A,Jones J,Ncongwane J,Segal I

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...

journal_title：Digestion

authors： Wen J,Liu Q,Song J,Tong M,Peng L,Liang H

更新日期：2013-01-01 00:00:00

abstract：:Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional cytokine which modifies tissue stromal matrix synthesis, cell proliferation and immune function. In the present study, we have used a mouse monoclonal antibody to the latent (intracytoplasmic) form of TGF-beta 1 to compare its expression in 144 cases ...

journal_title：Digestion

authors： Slater SD,Williamson RC,Foster CS

更新日期：1995-01-01 00:00:00

abstract：:Differential absorption of D-xylose and 3-O-methyl-D-glucose, and unmediated intestinal permeation of lactulose and L-rhamnose has been investigated in 14 patients with diarrhoea following tropical exposure and in 16 healthy control subjects. Five had malabsorption of fat, D-xylose and B12 ('tropical malabsorption' (T...

journal_title：Digestion

authors： Cook GC,Menzies IS

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although considerable information exists regarding gastroesophageal reflux disease with erosions, much less is known of non-erosive reflux disease (NERD), the dominant form of reflux disease in the developed world. METHODS:An expert international group using the modified Delphi technique examined the q...

journal_title：Digestion

authors： Modlin IM,Hunt RH,Malfertheiner P,Moayyedi P,Quigley EM,Tytgat GN,Tack J,Heading RC,Holtman G,Moss SF,Vevey NERD Consensus Group.

更新日期：2009-01-01 00:00:00

abstract：:Jejuno-ileal bypass (JIB) and resection are associated with hyperplastic and other changes in residual functional gut. In studies on endocrine changes, circulating hormone levels are usually measured. In this study with Sprague-Dawley rats, glucagon, secretin and vasoactive intestinal polypeptide (VIP), immunoreactivi...

journal_title：Digestion

authors： Murphy RF,Chen MH,Herlin PM,Gallavan RH,Joffe SN,Fischer JE

更新日期：1985-01-01 00:00:00

abstract：:We have shown that dietary long-chain triglycerides and 16,16-dimethyl prostaglandin E2 enhance and aspirin impairs postresection mucosal adaptation in rats. The present studies examined the hypothesis that supplemental linoleic acid (LA) above the minimum requirement may enhance postresection mucosal adaptation throu...

journal_title：Digestion

authors： Park JH,Grandjean CJ,Hart MH,Baylor JM,Vanderhoof JA

更新日期：1989-01-01 00:00:00

abstract：:Daily faecal calcium and magnesium outputs were inversely related to food-stimulated colonic intraluminal pressure in diverticular disease subjects. There was no relationship to sodium potassium and bile acid concentrations, nor to intestinal transit. ...

journal_title：Digestion

authors： Eastwood MA,Smith AN,Mitchell WD,Pritchard JL

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to see whether administration of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, could prevent the development of gastric cancer via inhibition of apurinic/apyrimidinic endonuclease-1 (APE-1) expression induced by Helicobacter pylori infection. METHODS:70 Mongol...

journal_title：Digestion

authors： Futagami S,Kawagoe T,Horie A,Shindo T,Hamamoto T,Suzuki K,Kusunoki M,Miyake K,Gudis K,Tsukui T,Crowe SE,Sakamoto C

更新日期：2008-01-01 00:00:00

abstract：:The influence of CDCA and UDCA administration on human intestinal permeability to lactulose, as disclosed by intravenous CCK, has been investigated. For this purpose the fraction of lactulose excreted in the urine during 5 h after an oral load of the disaccharide in hypertonic solution was measured in 12 healthy subje...

journal_title：Digestion

authors： Budillon G,Parrilli G,Capuano G,Mazzacca G,Menzies IS

更新日期：1982-01-01 00:00:00

abstract：:Rats were given 59Fe (28 micrograms) together with doses of 0, 2 and 200 micrograms of uroporphyrin III in paired observations. Absorption of 59Fe was determined by comparing whole body counts of the rats 30 min and 7 days after dosing. Prior treatment with 200 micrograms of uroporphyrin twice daily for 3 days was ass...

journal_title：Digestion

authors： Weaver GA,Franck CA,Harris MD,Peters T Jr

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Bile duct stones (BDS) are usually removed via endoscopic retrograde cholangiopancreatography (ERCP) or, if ERCP remains unsuccessful, percutaneous transhepatic cholangiodrainage (PTCD). However, PTCD provides limited access to large BDSs. We analyzed a modified approach of PTCD for percutaneous therapy of B...

journal_title：Digestion

authors： Hollenbach M,Feisthammel J,Mössner J,Hoffmeister A

更新日期：2018-01-01 00:00:00

abstract：:The urinary excretion rates of nitrate (NO3) and nitrite (NO2) were monitored in 14 patients with active ulcerative colitis during treatment using hydrocortisone and sulfasalazine. During the active phase of the disease, the NO3 excretion was significantly higher in the patients than in healthy controls (n = 6, p < 0....

journal_title：Digestion

authors： Sasajima K,Yoshida Y,Yamakado S,Sato J,Miyashita M,Okawa K,Matsutani T,Onda M,Kawano E

更新日期：1996-01-01 00:00:00

abstract：:Familial colorectal cancer (CRC) is heterogeneous. Screening recommendations do exist for individuals with a mild to moderate family history of CRC, with or without early age at onset. However, most attention has properly focused on the identification of individuals in whom a defined susceptibility gene mutation can b...

journal_title：Digestion

authors： Lynch PM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to analyze the endoscopic mucosal resection (EMR) with a novel uniquely shaped, double-loop snare (Dualoop, Medico's Hirata Inc., Tokyo, Japan) for colorectal polyps. METHODS:This was a clinical trial conducted in two referral centers, Kyoto Prefectural University of Medicine and Natio...

journal_title：Digestion

authors： Yoshida N,Saito Y,Hirose R,Ogiso K,Inada Y,Yagi N,Naito Y,Otake Y,Nakajima T,Matsuda T,Yanagisawa A,Itoh Y

更新日期：2014-01-01 00:00:00

abstract：AIM:To determine the long-term effect of argon plasma coagulation (APC) of gastric inlet patches in the cervical esophagus for patients suffering from globus sensation. METHODS:We intended to follow up all patients between 2004 and 2011 (n = 49) who received argon plasma ablation of gastric inlet patches for globus se...

journal_title：Digestion

authors： Klare P,Meining A,von Delius S,Wolf P,Konukiewitz B,Schmid RM,Bajbouj M

更新日期：2013-01-01 00:00:00

abstract：:Fasting reduced the weight, protein, DNA, RNA and polyamine contents of the small intestine of rats, but its effects on the in vivo uptake of intraperitoneally injected 14C-spermidine through the basolateral membrane of the small intestine were small. The uptake of putrescine was nearly doubled by fasting for 48 h. Fa...

journal_title：Digestion

authors： Bardócz S,Grant G,Brown DS,Ewen SW,Stewart JC,Pusztai A

更新日期：1991-01-01 00:00:00

abstract：:Rectal biopsies were maintained in organ culture over a 24-hour culture period, with good preservation of histological architecture. A filtrate containing Clostridium difficile toxin significantly inhibited the rise in epithelial alkaline phosphatase activity normally seen during culture. This effect was abolished by ...

journal_title：Digestion

authors： Allan A,Jewell DP

更新日期：1985-01-01 00:00:00

abstract：:The distribution of tryptophan hydroxylase, the rate-limiting enzyme in the biosynthesis of serotonin, was investigated immunohistochemically in various organs of the gastrointestinal tract and compared with that of neuroendocrine markers. While immunoreactivity for serotonin and chromogranin A was restricted to enter...

journal_title：Digestion

authors： Meyer T,Brinck U

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND AIM:Along with the widespread use of eradication for Helicobacter pylori (H. pylori), the incidence of gastric cancer after eradication has also been increasing. There is a need for clarification of the clinical and biological characteristics of these neoplasms. PATIENTS AND METHODS:We studied 27 cases ...

journal_title：Digestion

authors： Matsuo T,Ito M,Tatsugami M,Boda T,Takata S,Tanaka S,Chayama K

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...

journal_title：Digestion

authors： Pezzilli R,Billi P,Platè L,Bongiovanni F,Morselli Labate AM,Miglioli M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:In patients with active ulcerative colitis (UC), pharmacologics, although initially effective in most patients, are associated with refractoriness, loss of response or unfavourable side effects as additional morbidity factors. Depletion of myeloid lineage leucocytes like the CD14(+)CD16(+) monocyte phen...

journal_title：Digestion

authors： Iida T,Ikeya K,Kato M,Abe J,Yamamoto M,Watanabe F,Sugimoto K,Hanai H

更新日期：2017-01-01 00:00:00

abstract：AIM:Although pectin, a dietary fibre, has been suggested to possess some trophic effects on the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the effects of pectin on rat intestinal cell proliferation and the intraluminal environment. METHODS:Control and pectin-fed rats were given a f...

journal_title：Digestion

authors： Fukunaga T,Sasaki M,Araki Y,Okamoto T,Yasuoka T,Tsujikawa T,Fujiyama Y,Bamba T

更新日期：2003-01-01 00:00:00

abstract：:23 cirrhotics with ascites and sodium retention, whose aldosteronemia had been evaluated after an equilibration period at controlled sodium intake at the occasion of previous studies, were retrospectively investigated. The dosage of spironolactone needed to induce a negative sodium balance correlated significantly wit...

journal_title：Digestion

authors： Bernardi M,Servadei D,Trevisani F,Rusticali AG,Gasbarrini G

更新日期：1985-01-01 00:00:00

abstract：:A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...

journal_title：Digestion

authors： Allan BJ,White TT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND/AIMS:A trophic role of gastrin has been convincingly demonstrated in the oxyntic mucosa of the stomach, but is still a matter of debate in the lower gastrointestinal tract. METHODS:In order to examine the role of circulating gastrin in colorectal adenoma and carcinoma fasting serum gastrin concentrations we...

journal_title：Digestion

authors： Lamberts R,Wartenberg T,Creutzfeldt W

更新日期：1999-03-01 00:00:00

abstract：:Cholecystokinin (CCK) is known to inhibit gastric acid secretion and gastric emptying but its physiological role in the inhibition of gastric functions is not settled. In this study performed on 16 young male subjects, gastric acid secretion and emptying rate were determined after intragastric administration of 8% pep...

journal_title：Digestion

authors： Konturek SJ,Kwiecien N,Obtulowicz W,Kopp B,Oleksy J,Rovati L

更新日期：1990-01-01 00:00:00