Treatment Perspectives in Crohn's Disease.

abstract：:Previous studies suggested that gastrin-releasing peptide (a neuropeptide found in rat oxyntic mucosa) and oxyntomodulin (a glucagon-containing peptide of mammalian gut) could directly affect the acid secretion of the parietal cells. We therefore studied their effect on gastric acid production in vitro by measuring [1...

journal_title：Digestion

authors： Gehl J,Jeppesen JL,Poulsen SS,Holst JJ

更新日期：1988-01-01 00:00:00

abstract：:Biliopancreatic bypass (BPB), a bariatric surgical procedure, leads to a malnutrition-induced general visceral atrophy except for the pancreas. This work investigates the implication of cholecystokinin (CCK) in the exocrine pancreatic adaptive process using a plasma CCK assay and the CCK receptor antagonist CR 1409. N...

journal_title：Digestion

authors： Evrard S,Hoeltzel A,Aprahamian M,Bernard C,Mutter D,Marescaux J,Damgé C

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate whether the neuronal form of nitric oxide (NO) synthase (nNOS) in gastric mucosa differed from nNOS in the brain in subcellular distribution or antigenicity, and to determine the relative activity of the endothelial form of NO synthase (eNOS) and nNOS in gastric mucosa. METHODS:Subcellul...

journal_title：Digestion

authors： Price K,Hanson P

更新日期：1998-07-01 00:00:00

abstract：:The influence of CDCA and UDCA administration on human intestinal permeability to lactulose, as disclosed by intravenous CCK, has been investigated. For this purpose the fraction of lactulose excreted in the urine during 5 h after an oral load of the disaccharide in hypertonic solution was measured in 12 healthy subje...

journal_title：Digestion

authors： Budillon G,Parrilli G,Capuano G,Mazzacca G,Menzies IS

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Although pain is the most feared part of the terminal life of many patients with cancer, the intensity and the quality of the pain is all too often only scantly described. METHOD:The quality and quantity of pain were prospectively registered by five variables, including a visual analogue scale (VAS), in 46 ...

journal_title：Digestion

authors： Grahm AL,Andrén-Sandberg A

更新日期：1997-01-01 00:00:00

abstract：:The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...

journal_title：Digestion

authors： Gerbes AL,Hoermann R,Mann K,Jüngst D

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：:A highly significant increase in net fluxes across the guinea-pig small intestine for both 45Ca2+ and 35SO4(2-), in the presence of cystic fibrosis plasma compared with non-cystic fibrosis plasma, was observed (p less than 0.001). In the presence of cystic fibrosis plasma, the nuclear, mitochondrial, microsomal and so...

journal_title：Digestion

authors： Morrissey SM,Mehta JG

更新日期：1986-01-01 00:00:00

abstract：AIMS:The primary objective of this study was to clarify the influence of histotype on the outcome of D1/D2 gastrectomized patients with pathologically proven R0 resection. The secondary objective was to demonstrate overall survival (OS), disease-free survival (DFS), and locoregional recurrence rates following standard ...

journal_title：Digestion

authors： Uslu A,Bati H,Postaci H,Nart A,Eliyatkin N,Yetis H,Corumlu B,Aykas A,Zengel B

更新日期：2012-01-01 00:00:00

abstract：:Leukocytapheresis has recently been used to induce remission in patients with ulcerative colitis (UC) who fail to respond to corticosteroids. We could not find a report in the literature on leukocytapheresis for UC with gestational exacerbation. We have recently encountered this unique condition and report the details...

journal_title：Digestion

authors： Okada H,Makidono C,Takenaka R,Hiraoka S,Fujiwara A,Kato J,Kawahara Y,Kawamoto H,Mizuno M,Shiratori Y

更新日期：2006-01-01 00:00:00

abstract：:Rabbit duodenal and jejunal brush-border membrane vesicle integrity, fluidity and passive proton permeability were studied after in vitro exposure to deoxycholate, glycodeoxycholate or taurodeoxycholate. Duodenal and jejunal membrane mean vesicle volume [0.54 (0.05) and 0.54 (0.03) microliters/mg, mean values with SE ...

journal_title：Digestion

authors： Zhao DL,Hirst BH

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIM:Several studies performed in Western countries demonstrate the association between sleep dysfunction and gastroesophageal reflux disease (GERD), especially when nighttime heartburn is present. The purpose of this study was to examine the prevalence and risk factors of sleep dysfunction, and the effec...

journal_title：Digestion

authors： Fujiwara Y,Kohata Y,Kaji M,Nebiki H,Yamasaki T,Sasaki E,Hayakawa T,Machida H,Tanigawa T,Watanabe K,Watanabe T,Tominaga K,Arakawa T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate genotyping for two DNA variants (c.1993+327C>T and c.1438+117G>A), recently found to be associated with adult-type hypolactasia, in the diagnosis of lactose intolerance. METHODS:In total, 166 consecutive patients with gastrointestinal symptoms mimicking hypolactasia admitted to the clin...

journal_title：Digestion

authors： Büning C,Genschel J,Jurga J,Fiedler T,Voderholzer W,Fiedler EM,Worm M,Weltrich R,Lochs H,Schmidt H,Ockenga J

更新日期：2005-01-01 00:00:00

abstract：:Autonomic hyperactivity with increased cardiac output and other manifestations occurs in patients with both cirrhosis and noncirrhotic portal hypertension. The role of the disordered hepatic autonomic innervation in the mediation of these abnormalities is unknown. We have studied the hepatic nerve network and associat...

journal_title：Digestion

authors： Jaskiewicz K,Voigt MD,Robson SC

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The authors reported that the repair of submucosal tissue is important in ulcer healing. The kinetics of fibroblasts have not been well known in gastric ulcer healing. The effect of subcutaneous administration of indomethacin (1 mg/kg) to submucosal tissue was also examined. METHOD:Immunohistological stainin...

journal_title：Digestion

authors： Hirose Y,Goto H,Arisawa T,Hase S,Niwa Y,Hayakawa T,Asai J,Tsukamoto Y

更新日期：1997-01-01 00:00:00

abstract：:Daily faecal calcium and magnesium outputs were inversely related to food-stimulated colonic intraluminal pressure in diverticular disease subjects. There was no relationship to sodium potassium and bile acid concentrations, nor to intestinal transit. ...

journal_title：Digestion

authors： Eastwood MA,Smith AN,Mitchell WD,Pritchard JL

更新日期：1980-01-01 00:00:00

abstract：:Mortality data for ulcerative colitis, Crohn's disease, and unspecified inflammatory bowel disease were examined for the countries Venezuela, Italy, and France during the decade 1969-1978. These figures were compared with similar data from England and Wales obtained from 1965 to 1975. In Italy and France deaths from C...

journal_title：Digestion

authors： D'Oliveira R,Mayberry JF,Newcombe RG,Rhodes J

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS:Probiotics appear to improve Helicobacter pylori-associated dyspepsia via an inhibitory effect on H. pylori; however, uncertainty exists regarding their effects in H. pylori-uninfected individuals. We evaluated the efficacy of Lactobacillus gasseri OLL2716 (L. gasseri OLL2716) on H. pylori-uninfected in...

journal_title：Digestion

authors： Ohtsu T,Takagi A,Uemura N,Inoue K,Sekino H,Kawashima A,Uchida M,Koga Y

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:We have used the Zucker diabetic fatty (ZDF) rat to study the effects of type-2 diabetes and troglitazone on the small intestinal mucosal mass, sugar transporters and the peroxisomal proliferator-activated receptor, PPAR-gamma. METHODS:Age-matched ZDF and lean control (ZLC) rats were fed a standard cho...

journal_title：Digestion

authors： Corpe C,Sreenan S,Burant C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:In this study, a clinical and serological follow-up of 8-10 years was performed in relatives of celiac disease (CD) patients from southern Brazil. The occurrence of new CD cases in the families and the use of two different IgA-tTG enzyme-linked immunosorbent assay (ELISA) kits were also evaluated. METH...

journal_title：Digestion

authors： Nass FR,Kotze LM,Nisihara RM,de Messias-Reason IJ,Ramos da Rosa Utiyama S

更新日期：2011-01-01 00:00:00

abstract：:Eighteen cases of severe hyperplasia of fundic argyrophil cells observed during routine histologic examination of endoscopic gastric biopsy specimens from unselected patients with upper gastro-intestinal symptomatology were investigated. All patients, except one, were female with a mean age of 57 years. Atrophic gastr...

journal_title：Digestion

authors： Bordi C,Pilato F,Carfagna G,Ferrari C,D'Adda T,Sivelli R,Bertelé A,Missale G

更新日期：1986-01-01 00:00:00

abstract：:This study was conducted to investigate whether chronic kidney disease (CKD) affects intestinal inflammation and intestinal motility and the underlying mechanisms. Rats were randomized into control group and uremic group. Uremia rats were induced by the 5/6 kidney resection, while the control went through the same pro...

journal_title：Digestion

authors： Yu C,Tan S,Wang Z,Deng B,Li J,Wang Q,Zhou C,Kang X,Yu Z,Zhuang S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) of early esophageal cancer (EC) is becoming more widespread. Post-ESD coagulation syndrome (CS) has been proposed as temporary inflammatory signs that occur during the post-ESD period caused by transmural thermal injury by electrocoagulation. This retrospective study ai...

journal_title：Digestion

authors： Sakai M,Sohda M,Saito H,Ubukata Y,Nakazawa N,Kuriyama K,Hara K,Sano A,Ogata K,Yokobori T,Kuwano H,Shirabe K,Saeki H

更新日期：2020-10-08 00:00:00

abstract：:We have followed the time-course of the morphological and functional recovery of intestinal mucosa after 90 min of mesenteric vascular occlusion. At the end of the ischemic period the villi were smashed, but crypts were preserved. Microvillous hydrolase activities showed a dramatic drop when compared with sham-operate...

journal_title：Digestion

authors： Kummerlen C,Seiler N,Galluser M,Gossé F,Knodgen B,Hasselmann M,Raul F

更新日期：1994-01-01 00:00:00

abstract：:Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

journal_title：Digestion

authors： Okabe S,Tabata K

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND/AIMS:Several earlier studies on factors predicting the long-term outcome of ulcerative colitis only encompassed treatment failure for one severe episode, or suffered from a lack of multivariate analyses. We aimed to identify factors assessable at diagnosis or after the first induction therapy which predicted...

journal_title：Digestion

authors： Shiga H,Takagi S,Inoue R,Kinouchi Y,Ohkubo T,Takahashi S,Negoro K,Yokoyama H,Kato S,Fukushima K,Hiwatashi N,Shimosegawa T

更新日期：2010-01-01 00:00:00

abstract：:Buffalo strain male and female rats were given methylazoxymethanol acetate (20% solution) intraperitoneally 20 mg/kg body weight weekly for 9 weeks, and killed 27 weeks later. Carcinomas of the large intestine, predominantly in the descending colon, developed in some of the rats. The incidence was higher in male than ...

journal_title：Digestion

authors： Reuber MD

更新日期：1976-01-01 00:00:00

abstract：:Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients. However, because reflux oesophagitis relapses rapidly when short-term treatment is dis...

journal_title：Digestion

authors： Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：:Neutrophil motility in normal subjects and Crohn's disease patients was assessed using both double and single filter assay systems with n-formylmethionylleucylphenylalanine (FMLP) as the attractant, and in a single filter assay with Candida albicans in 10% serum as the attractant. Assays were performed in triplicate a...

journal_title：Digestion

authors： Curran FT,Keighley MR

更新日期：1991-01-01 00:00:00

abstract：:Rats were subjected to serial venesections 3 days prior to and then sequentially for 4 weeks after surgical removal of either the proximal or distal half of the small bowel. Total serum protein concentration and protein electrophoretic patterns were determined on these sera. Both sham-operated and unoperated animals s...

journal_title：Digestion

authors： Urban E,Ricks PM

更新日期：1980-01-01 00:00:00