Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis.

abstract：:In the dog pancreas in vivo, the biological activity of secretin and vasoactive intestinal peptide was compared to that of secretin analogues modified in their N-terminal hexapeptide and to X-secretion (alpha, beta-Asp3-secretin) and Y-secretin (a conversion product of X-secretin consisting of about 15% secretin and 8...

journal_title：Digestion

authors： Lehnert P,Forell MM,Jaeger E,Moroder L,Wünsch E

更新日期：1981-01-01 00:00:00

abstract：:Growth hormone-releasing factor (GRF) was reported to possess the growth-promoting action on the gastroduodenal mucosa that can be augmented by removal of endogenous somatostatin. Since mucosal proliferation was considered to contribute to healing of chronic gastroduodenal ulcerations, we designed the study to determi...

journal_title：Digestion

authors： Konturek SJ,Brzozowski T,Dembinski A,Warzecha Z,Konturek PK,Yanaihara N

更新日期：1988-01-01 00:00:00

abstract：:The core symposiums of the Japanese Gastroenterological Association (JGA) annual scientific meetings focus on similar topics from year to year. The main topics of these symposiums for the last 3 years were centered on progress in new diagnostics and therapeutic strategies for gastrointestinal malignancy, with a specia...

journal_title：Digestion

authors： Sugiyama T

更新日期：2015-01-01 00:00:00

abstract：:The activities of pancreatic enzymes decrease during their passage from the duodenum to the terminal ileum, but degradation rates of individual enzymes are different. Whereas lipase activity is lost most rapidly, proteases and amylase are more stable. The mechanism by which lipase activity is destroyed is proteolysis,...

journal_title：Digestion

authors： Layer P,Gröger G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND/AIMS:Currently, a split-dose of polyethylene glycol (PEG) is the mainstay of bowel preparation due to its tolerability, bowel-cleansing action, and safety. However, bowel preparation with PEG is suboptimal because residual fluid reduces the polyp detection rate and requires a more thorough colon inspection. ...

journal_title：Digestion

authors： Kim HJ,Kim TO,Shin BC,Woo JG,Seo EH,Joo HR,Heo NY,Park J,Park SH,Yang SY,Moon YS,Shin JY,Lee NY

更新日期：2012-01-01 00:00:00

abstract：:Malabsorption syndromes are commonly caused by pathological interferences of normal digestive processes. In the last several years major advances in the diagnosis and treatment of these syndromes has emerged. This review will focus on diseases in which the mucosal phase of the digestive process is predominately distur...

journal_title：Digestion

authors： Sun DF,Fang JY

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this study was to exactly determine the pH stability of human gastric lipase (HGL) and to investigate the mechanism underlying the inactivation of HGL which occurs in gastric juice. METHODS:Samples of human gastric juice and purified HGL were incubated at various pH values ranging from 0.5 t...

journal_title：Digestion

authors： Ville E,Carrière F,Renou C,Laugier R

更新日期：2002-01-01 00:00:00

abstract：:The aim of the study was to define the effects of sex, age, smoking, alcohol, analgesic ingestion, and treatment method whereby healing was initially induced on the prognosis of patients with a chronic duodenal ulcer (DU). 122 patients were assessed 1 year after the endoscopic demonstration of a DU. Two outcome variab...

journal_title：Digestion

authors： Piper DW,McIntosh JH,Hudson HM

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:Defective epithelial barrier has been implicated in the pathogenesis of irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was to investigate gut permeability in patients with inactive ulcerative colitis (UC) and in patients with IBS. METHODS:IBS patients of the diarr...

journal_title：Digestion

authors： Gecse K,Róka R,Séra T,Rosztóczy A,Annaházi A,Izbéki F,Nagy F,Molnár T,Szepes Z,Pávics L,Bueno L,Wittmann T

更新日期：2012-01-01 00:00:00

abstract：:We studied the functional coupling between antral somatostatin and gastrin cells in pigs using isolated perfused preparations of the antrum with intact supply of the vagus nerves. Luminal acidification significantly inhibited gastrin secretion to 61 +/- 3% of basal secretion and increased somatostatin output 9-fold. I...

journal_title：Digestion

authors： Holst JJ,Orskov C,Seier-Poulsen S

更新日期：1992-01-01 00:00:00

abstract：:Nine patients with short bowel syndrome and high intestinal output received octreotide either intravenously (50-100 micrograms t.i.d.) or subcutaneously (100 micrograms b.i.d.) on 2 test days. In the 6 patients with net secretory output, there was a reduction in mean daily intestinal output of 0.5-5.0 kg; total daily ...

journal_title：Digestion

authors： Nightingale JM,Walker ER,Burnham WR,Farthing MJ,Lennard-Jones JE

更新日期：1990-01-01 00:00:00

abstract：AIMS:To evaluate the prevalence of proximal reflux and esophago-bronchial reflex (EBR) in patients with asthma, and to compare the symptom spectrum, esophageal acid sensitivity, pH monitoring, and the endoscopic and manometric parameters of EBR-positive and -negative patients with asthma. PATIENTS AND METHODS:Forty-th...

journal_title：Digestion

authors： Rosztóczy A,Makk L,Izbéki F,Róka R,Somfay A,Wittmann T

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Polyamine uptake from the circulation plays an important role in the maintenance of the intracellular polyamine content during extensive proliferation in intestinal mucosal cells. METHODS:Isolated basolateral membrane vesicles of the rabbit enterocyte were used to characterize polyamine transport acros...

journal_title：Digestion

authors： Milovic V,Caspary WF,Stein J

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Overt hepatic encephalopathy (HE) following insertion of a transjugular intrahepatic portosystemic shunt (TIPS) is a problem in some patients. In contrast to overt HE, minimal HE (MHE) following TIPS is studied to a limited degree only. We therefore evaluated the incidence of MHE in patients following TIPS i...

journal_title：Digestion

authors： Biecker E,Hausdörfer I,Grünhage F,Strunk H,Sauerbruch T

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：:The form in which copper is bound in bile was studied in bile from patients with Wilson's disease, control subjects and rats. Bile was labelled with 64Cu. Sephadex column chromatography using gels G-200--G-10 showed a major 64Cu and protein peak of about 5,000 daltons and a minor peak of about 8,000 daltons. A high-mo...

journal_title：Digestion

authors： Frommer DJ

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND/AIM:Diarrhoea in collagenous colitis has been considered as secretory though the pathophysiology has been studied thoroughly in only a few patients. The result of fasting is one way to distinguish between secretory and osmotic diarrhoea. Our aim was to investigate the effect of fasting on diarrhoea in collag...

journal_title：Digestion

authors： Bohr J,Järnerot G,Tysk C,Jones I,Eriksson S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the effects of proton pump inhibitors on symptomatic inflammatory esophagogastric polyps (IEPs) in a pediatric cohort and to determine the optimal duration of treatment. METHODS:The 11 patients with IEPs were managed with lansoprazole. Follow-up endoscopies were perf...

journal_title：Digestion

authors： Choi KE,Kim MJ,Lee JH,Lee JS,Lee JH,Choe YH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:A recent basic study identified that Dicer is contained in exosomes derived from cancer cells and plays crucial roles in microRNA maturation and cancer development. Based on this novel basic concept, we analyzed the usefulness of serum exosomal Dicer as a diagnostic biomarker for gastrointestinal can...

journal_title：Digestion

authors： Okuda Y,Shimura T,Iwasaki H,Katano T,Kitagawa M,Nishigaki R,Fukusada S,Natsume M,Tanaka M,Nishie H,Ozeki K,Yamada T,Kataoka H

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to analyze the endoscopic mucosal resection (EMR) with a novel uniquely shaped, double-loop snare (Dualoop, Medico's Hirata Inc., Tokyo, Japan) for colorectal polyps. METHODS:This was a clinical trial conducted in two referral centers, Kyoto Prefectural University of Medicine and Natio...

journal_title：Digestion

authors： Yoshida N,Saito Y,Hirose R,Ogiso K,Inada Y,Yagi N,Naito Y,Otake Y,Nakajima T,Matsuda T,Yanagisawa A,Itoh Y

更新日期：2014-01-01 00:00:00

abstract：:We studied the pancreatic secretory response to sham feeding alone or during secretin infusion with and without administration of atropine in 10 human subjects. The magnitude of the response to sham feeding was compared to the response to cholecystokinin octapeptide. Sham feeding alone did not significantly increase p...

journal_title：Digestion

authors： Defilippi C,Solomon TE,Valenzuela JE

更新日期：1982-01-01 00:00:00

abstract：:Surgery is the only potentially curative treatment for patients with carcinoid tumors. Patients with localized disease even with lymph node metastases can be resected for potential cure. Patients with distant metastatic disease have been reported to be cured by resection of all tumor. However, long-term follow-up of t...

journal_title：Digestion

authors： Norton JA

更新日期：1994-01-01 00:00:00

abstract：:An improved GLC method was employed to study individual serum bile acids in 14 control subjects after a 12-hour fast followed by a standard fatty meal. Peripheral venous blood samples were obtained at 15-min intervals for up to 2 h in 7 subjects, and 4 h in 2 subjects. The fasting total bile acids, and cholic:chenodeo...

journal_title：Digestion

authors： Pennington CR,Ross PE,Bouchier IA

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Validity of the lactulose breath test (LBT) to diagnose small intestinal bacterial overgrowth (SIBO) has been questioned. Therefore, a study was planned to compare LBT with glucose breath test (GBT) to diagnose SIBO in irritable bowel syndrome (IBS) patients and controls. METHODS:175 diarrhea-predo...

journal_title：Digestion

authors： Rana SV,Sharma S,Kaur J,Sinha SK,Singh K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIMS:There are limited data concerning the clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) after double-balloon endoscopy (DBE). The aim of the present study was to evaluate the long-term outcome of patients with OGIB after DBE. PATIENTS AND METHODS:Eighty-seven consecutive pa...

journal_title：Digestion

authors： Fujita M,Manabe N,Honda K,Tarumi K,Murao T,Katada S,Kimura Y,Matsumoto H,Kamada T,Shiotani A,Hata J,Haruma K

更新日期：2010-01-01 00:00:00

abstract：:5 healthy volunteers were submitted to i.v. infusion for 45 min of graded doses of commercial GIH secretin (0.01, 0.025, 0.05, 0.5, 1 and 2 CU/kg h-1). Parathormone serum levels were measured before and during the infusion. All the dosages of exogenous secretin were followed by a significant increase in serum PTH leve...

journal_title：Digestion

authors： Piubello W,Cominacini L,Vantini I,Brocco G,Benini L,Cavallini G,Lo Cascio V,Scuro LA

更新日期：1981-01-01 00:00:00

abstract：:The luminal mucus layer of the rat's small intestine was separated from the mucosa by filling the lumen with agar jelly. When the rats were fasted overnight and given 59Fe or 65Zn by stomach tube the mucus isolated by this technique contained more isotope and more sialic acid than fed controls, and more of the isotope...

journal_title：Digestion

authors： Quarterman J

更新日期：1987-01-01 00:00:00

abstract：:Sedation and analgesia is the standard of care during diagnostic and therapeutic endoscopic gastrointestinal procedures in most areas of the world. Unsedated endoscopy is feasible in selected patients, but requires commitment on the part of both the patient and the provider. The American Society of Anesthesiologists h...

journal_title：Digestion

authors： Paspatis GA,Tribonias G,Paraskeva K

更新日期：2010-01-01 00:00:00

abstract：:Recently our studies have demonstrated that the central nervous system regulates in part mucosal cell growth and apoptosis in the rat small intestine. Ornithine decarboxylase (ODC) activity is a key enzyme for polyamine synthesis which plays an important role for the intestinal mucosal growth. We have demonstrated tha...

journal_title：Digestion

authors： Fujimoto K,Iwakiri R,Utsumi H,Kojima M,Ishibashi S,Wu B,Sakata H,Noda T

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...

journal_title：Digestion

authors： Takeshita E,Sakata Y,Hara M,Akutagawa K,Sakata N,Endo H,Ohyama T,Matsunaga K,Yoshioka T,Kawakubo H,Tanaka Y,Shirai S,Ito Y,Tsuruoka N,Iwakiri R,Kusano M,Fujimoto K

更新日期：2016-01-01 00:00:00