Endoscopic mucosal resection for middle and large colorectal polyps with a double-loop snare.

Abstract:

BACKGROUND/AIMS:This study aimed to analyze the endoscopic mucosal resection (EMR) with a novel uniquely shaped, double-loop snare (Dualoop, Medico's Hirata Inc., Tokyo, Japan) for colorectal polyps. METHODS:This was a clinical trial conducted in two referral centers, Kyoto Prefectural University of Medicine and National Cancer Center Hospital in Japan. First, the firmness of various snares including 'Dualoop' was experimentally analyzed with a pressure gauge. Five hundred and eighty nine consecutive polyps that underwent EMR with 'Dualoop' were compared to 339 polyps with the standard round snare. Lesion characteristics, en bloc resection, and complications were analyzed. RESULTS:'Dualoop' had the most firmness among the various snares. The average tumor size was 9.3 mm (5-30), and en bloc resection was achieved in 95.4%. The rate of en bloc resection for middle polyps 15-19 mm in diameter was significantly higher with the 'Dualoop' than that with the round snare (97.9 vs. 80.0%, p < 0.05). The rate of en bloc resection was 64.7% for large polyps ≥20 mm in diameter using 'Dualoop'. Higher age, larger tumor size, and superficial polyps were associated with the failure of en bloc resection. CONCLUSION:EMR with 'Dualoop' was effective for resecting both middle and large polyps en-bloc.

journal_name

Digestion

journal_title

Digestion

authors

Yoshida N,Saito Y,Hirose R,Ogiso K,Inada Y,Yagi N,Naito Y,Otake Y,Nakajima T,Matsuda T,Yanagisawa A,Itoh Y

doi

10.1159/000368044

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

232-9

issue

4

eissn

0012-2823

issn

1421-9867

pii

000368044

journal_volume

90

pub_type

杂志文章
  • Gastric cytoprotection by acetazolamide: role of endogenous prostaglandins.

    abstract::This study was designed to determine the influence of acetazolamide, a potent inhibitor of carbonic anhydrase, on the formation of gastric mucosal lesions induced by acidified aspirin (ASA) or absolute ethanol and on gastric cytoprotection induced by prostaglandin E2 (PGE2). Acetazolamide prevented dose-dependently et...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198975

    authors: Konturek SJ,Brzozowski T,Piastucki I,Radecki T

    更新日期:1983-01-01 00:00:00

  • The possible role of bicarbonate in mucosal protection and peptic ulceration.

    abstract::The surface epithelial cells of the gastroduodenal mucosa are thought to be protected from the damaging effects of acid by a covering layer of mucus into which is secreted bicarbonate. It is proposed here that mucus acts as a true barrier to hydrogen ion diffusion, and that the role played by bicarbonate is to adjust ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198954

    authors: Vadgama P,Alberti KG

    更新日期:1983-01-01 00:00:00

  • Radioisotope-guided surgery in patients with neuroendocrine tumours.

    abstract::We evaluated a hand-held scintillation detector for intra-operative localisation of somatostatin-receptor-positive tumours in situ, and after excision, as an addition to preoperative scintigraphy with [111In-DTPA-Phe1]octreotide. Using the hand-held detector, the suspect tumour/normal tissue ratio R(in situ) between m...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201406

    authors: Ahlman H

    更新日期:1996-01-01 00:00:00

  • Human pancreas-specific protein/procarboxypeptidase B: a useful serum marker of acute pancreatitis.

    abstract::The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000201128

    authors: Pezzilli R,Billi P,Platè L,Bongiovanni F,Morselli Labate AM,Miglioli M

    更新日期:1994-01-01 00:00:00

  • Analysis of Wire-Guided Hemostasis Introducer for Percutaneous Therapy of Bile Duct Stones.

    abstract:BACKGROUND:Bile duct stones (BDS) are usually removed via endoscopic retrograde cholangiopancreatography (ERCP) or, if ERCP remains unsuccessful, percutaneous transhepatic cholangiodrainage (PTCD). However, PTCD provides limited access to large BDSs. We analyzed a modified approach of PTCD for percutaneous therapy of B...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000485179

    authors: Hollenbach M,Feisthammel J,Mössner J,Hoffmeister A

    更新日期:2018-01-01 00:00:00

  • Metabolic Alterations in Celiac Disease Occurring after Following a Gluten-Free Diet.

    abstract:BACKGROUND AND AIM:Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000495749

    authors: Ciccone A,Gabrieli D,Cardinale R,Di Ruscio M,Vernia F,Stefanelli G,Necozione S,Melideo D,Viscido A,Frieri G,Latella G

    更新日期:2019-01-01 00:00:00

  • Quantitative histomorphometric study of the jejunal mucosa in chronic alcoholics.

    abstract::Jejunal suction biopsies of 18 chronic alcoholics (alcohol intake of more than 100 g of ethanol per day for several years) and 10 nonalcoholic control subjects were analyzed quantitatively using the microdissection technique described by Clarke. Both groups were comparable concerning age, body weight and sex. The dura...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198760

    authors: Bode JC,Knüppel H,Schwerk W,Lorenz-Meyer H,Dürr HK

    更新日期:1982-01-01 00:00:00

  • Evaluating the Accuracy of the Endoscopic ABC Classification System in Diagnosing Helicobacter pylori-Infected Gastritis.

    abstract:AIMS:Evaluating the accuracy of the modified Endoscopic ABC (Endo ABC) classification with an electronic endoscopy with narrow band imaging without magnification in diagnosing Helicobacter pylori (H. pylori)-infected gastritis. METHODS:A total of 576 patients were enrolled and they underwent modified Endo ABC. They we...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000498966

    authors: Inui M,Ohwada S,Inui Y,Kondo Y,Moro A,Sasaki K

    更新日期:2020-01-01 00:00:00

  • Carotid intima-media thickness is increased not only in non-alcoholic fatty liver disease patients but also in alcoholic fatty liver patients.

    abstract:BACKGROUND/AIMS:There are many reports of non-alcoholic fatty liver disease (NAFLD) patients with increased carotid intima-media thickness (IMT). However, there is little information about carotid IMT in alcoholic fatty liver disease (AFLD) patients. We aimed to compare the carotid IMT of NAFLD patients and AFLD patien...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000326854

    authors: Kim JH,Kim SY,Jung ES,Jung SW,Koo JS,Kim JH,Yeon JE,Kwon SY,Lee SW,Byun KS,Lee CH

    更新日期:2011-01-01 00:00:00

  • Virus-associated receptors for polymerized human serum albumin (RpHSA) in patients with chronic active hepatitis B treated with recombinant leukocyte A interferon.

    abstract::Hepatitis B surface antigen (HBsAg)-associated receptors for polymerized human serum albumin (RpHSA) are assumed to mediate viral attachment to hepatocytes in hepatitis B virus (HBV) infection. RpHSA was found to be coded by the pre-S region of HBV genome. Recently, the antiviral effect of recombinant leukocyte alpha-...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199474

    authors: Gerken G,Manns M,Hess G,Meyer zum Büschenfelde KH

    更新日期:1987-01-01 00:00:00

  • Functional renal alterations in chronic liver diseases.

    abstract::83 patients with chronic active hepatitis (CAH), 38 of them with cirrhosis, were studied and compared with 10 control subjects suffering from chronic persistent hepatitis (CPH). Tubular acidosis frequently was found in our cases. Renal plasma flow and glomerular filtration rate were significantly decreased in CAH when...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198421

    authors: Gentilini P,Laffi G,Buzzelli G,Stefani P,Scarpelli P,Paladini S,Smorlesi C,La Villa G,Forti G

    更新日期:1980-01-01 00:00:00

  • Immature parietal cells in healing gastric wounds respond to stimulation. An experimental study in rats.

    abstract::Ulcers were produced in the gastric mucosa in rats. After 90 days of healing, one group of animals was given pentagastrin and carbacholine via continuous subcutaneous infusion. After 1 h the animals were killed and the wounds and normal mucosa beside the wounds were prepared for electron microscopy. Stereological anal...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198771

    authors: Blom H

    更新日期:1982-01-01 00:00:00

  • Establishment and characterization of two new rectal neuroendocrine cell carcinoma cell lines.

    abstract:BACKGROUND:Human colorectal neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. The biological behavior of NEC remains poorly understood. MATERIALS AND METHODS:We established two new NEC cell lines from a patient with rectal neuroendocrine carcinoma, NECS-P and NECS-L from the primary tumor an...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007825

    authors: Takahashi Y,Onda M,Tanaka N,Seya T

    更新日期:2000-01-01 00:00:00

  • The Ameliorating Effect of Switching to Vonoprazan: A Novel Potassium-Competitive Acid Blocker in Patients with Proton Pump Inhibitor Refractory Non-Erosive Reflux Disease.

    abstract:INTRODUCTION:Weakly acidic reflux has been reported to be the major cause of symptoms in patients with proton pump inhibitor (PPI)-refractory nonerosive reflux disease (NERD) undergoing PPI treatment. We previously reported that reflux at pH 4-5 was the main factor that induced symptoms in such patients. The present st...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000506152

    authors: Abe Y,Koike T,Saito M,Okata T,Nakagawa K,Hatta W,Asanuma K,Uno K,Asano N,Imatani A,Masamune A

    更新日期:2020-02-14 00:00:00

  • The utility of cellulose meals for studies on gastrointestinal motility in dogs.

    abstract::This study evaluated the effect of a cellulose meal and a cellulose-oleic acid meal on gastroduodenal motility and gastric emptying. The cellulose meal produced a high antral motility index (100 +/- 34 V/10 min) and a high proportion (80.2%) of propulsive duodenal contractions. The oleic acid meal was associated with ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198829

    authors: Schemann M,Ehrlein HJ

    更新日期:1982-01-01 00:00:00

  • Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats.

    abstract::The effect of the new antiulcer agent plaunotol on the release of endogenous secretin and the pancreatic exocrine secretion was investigated in anesthetized rats. In 48 rats with pancreatic and biliary diversion, continuous intraduodenal infusion of plaunotol in 3 graded doses (5, 20 and 80 mg/h/rat) resulted in signi...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199903

    authors: Chang JH,Watanabe S,Shiratori K,Moriyoshi Y,Takeuchi T

    更新日期:1989-01-01 00:00:00

  • Endoscopic Ultrasound Elastography as a Novel Diagnostic Method for the Assessment of Hardness and Depth of Invasion in Colorectal Neoplasms.

    abstract:INTRODUCTION:We aimed to compare the efficacy of endoscopic ultrasound elastography (EUS-EG) with that of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for the diagnosis of the depth of invasion in colorectal neoplasms. This is an important clinical issue as the depth of invasion is associated w...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000511589

    authors: Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Suzuki H,Kuno T,Yamada K,Hasegawa I,Ishikawa T,Kakushima N,Furukawa K,Ohno E,Kawashima H,Hirooka Y,Fujishiro M

    更新日期:2020-11-18 00:00:00

  • Chronic Kidney Disease Elicits an Intestinal Inflammation Resulting in Intestinal Dysmotility Associated with the Activation of Inducible Nitric Oxide Synthesis in Rat.

    abstract::This study was conducted to investigate whether chronic kidney disease (CKD) affects intestinal inflammation and intestinal motility and the underlying mechanisms. Rats were randomized into control group and uremic group. Uremia rats were induced by the 5/6 kidney resection, while the control went through the same pro...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000481618

    authors: Yu C,Tan S,Wang Z,Deng B,Li J,Wang Q,Zhou C,Kang X,Yu Z,Zhuang S

    更新日期:2018-01-01 00:00:00

  • Self-Completion Method of Endoscopic Submucosal Dissection Using Endosaber without Any Other Device or Assistance: An ex vivo Porcine Model Study.

    abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) is a standard treatment for tumors of the gastrointestinal tract. We developed a self-completion method of ESD using Endosaber to eliminate the need for an additional device or human assistance during the procedure. The aim of this study was to evaluate the technical fe...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000502771

    authors: Esaki M,Minoda Y,Wada M,Sakisaka S,Tsuruta S,Hosokawa T,Matsuguchi T,Ichijima R,Suzuki S,Tamura Y,Iwao A,Yamakawa S,Irie A,Ihara E,Ogawa Y

    更新日期:2019-09-27 00:00:00

  • Esophageal Cancer: New Insights into a Heterogenous Disease.

    abstract:BACKGROUND:Esophageal cancer represents a heterogeneous malignancy mostly diagnosed in advanced stages. Worldwide, squamous cell carcinomas (SCCs) continue to be the most prevalent subtype; however, in the Western countries, the incidence of adenocarcinomas is increasing and will exceed that of SCC in the near future. ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000464130

    authors: Krug S,Michl P

    更新日期:2017-01-01 00:00:00

  • Advantages of fecal lactoferrin measurement during granulocyte and monocyte adsorptive apheresis therapy in ulcerative colitis.

    abstract:BACKGROUND:Fecal lactoferrin has been introduced as a useful tool for the diagnosis and monitoring of inflammatory bowel disease (IBD). The aim of this study was to assess if fecal lactoferrin can be employed to predict or estimate the effect of granulocyte and monocyte adsorptive apheresis (GMA) in ulcerative colitis ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000375301

    authors: Hashiguchi K,Takeshima F,Akazawa Y,Matsushima K,Minami H,Machida H,Yamaguchi N,Shiozawa K,Ohba K,Ohnita K,Ichikawa T,Isomoto H,Nakao K

    更新日期:2015-01-01 00:00:00

  • Sedation training using a human patient simulator.

    abstract::High-fidelity simulation uses simulators that combine all of the physiological and pharmacological responses of a human in a manikin. These simulators change and respond to the users and trainees. Using simulators for teaching sedation in the field of gastroenterology unifies all the advantages of manikins. To underst...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000287214

    authors: Hofmann N,Datz C,Schöchl H

    更新日期:2010-01-01 00:00:00

  • Zinc deficiency in Crohn's disease.

    abstract::Zinc nutriture has been studies in 30 patients with Crohn's disease using plasma zinc, hair zinc, and taste acuity as indices. Significant reductions in plasma zinc concentrations and taste acuity were seen in the patient groups as compared with normal controls. Hair zinc content was also generally low with several de...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198059

    authors: Solomons NW,Rosenberg IH,Sandstead HH,Vo-Khactu KP

    更新日期:1977-01-01 00:00:00

  • Caspase-4 activation in association with decreased adenosine deaminase activity may be a factor for gastric ulcer.

    abstract:BACKGROUND/AIMS:Adenosine deaminase (ADA)-deficient disease, a severe combined immunodeficiency, is most commonly associated with gastrointestinal disorders such as ulcer. The present study investigated the role of ADA in the pathogenesis of gastric ulcer. METHODS:ADA activity was measured in a variety of organs and t...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000252771

    authors: Yaguchi T,Saito M,Yasuda Y,Nishizaki T

    更新日期:2010-01-01 00:00:00

  • Gastric cancer development after Helicobacter pylori eradication therapy: a new form of gastric neoplasia.

    abstract:BACKGROUND AND AIM:Along with the widespread use of eradication for Helicobacter pylori (H. pylori), the incidence of gastric cancer after eradication has also been increasing. There is a need for clarification of the clinical and biological characteristics of these neoplasms. PATIENTS AND METHODS:We studied 27 cases ...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000335260

    authors: Matsuo T,Ito M,Tatsugami M,Boda T,Takata S,Tanaka S,Chayama K

    更新日期:2012-01-01 00:00:00

  • Functional expression of HGF and its receptor in human colorectal cancer.

    abstract:BACKGROUND:Hepatocyte growth factor (HGF) stimulates proliferation, migration and morphogenesis of epithelial cells by specific binding to its receptor c-met. Overexpression of HGF or c-met has been reported for human gastric or pancreatic cancer. In colorectal cancer overexpression of c-met but not HGF has been shown....

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000007764

    authors: Otte JM,Schmitz F,Kiehne K,Stechele HU,Banasiewicz T,Krokowicz P,Nakamura T,Fölsch UR,Herzig K

    更新日期:2000-01-01 00:00:00

  • Predictors for Complicated Disease Course after Stepping Down from Combination to Antitumor Necrosis Factor Alpha Monotherapy in Children with Inflammatory Bowel Disease.

    abstract:OBJECTIVE:Combinations of antitumor necrosis factor alpha (TNFα) and immunomodulators may be indicated in high-risk inflammatory bowel disease patients. Our aims were to compare disease course between children that did and did not step down to anti-TNFα monotherapy and to define risk factors for complicated disease cou...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000496273

    authors: Yerushalmy-Feler A,Moran-Lev H,Galai T,Cohen S

    更新日期:2020-01-01 00:00:00

  • Cytoprotection of canine gastric mucosa by prostacyclin: possible mediation by increased mucosal blood flow.

    abstract:UNLABELLED:This study examined the role of the gastric mucosal blood flow (MBF) in the gastric cytoprotection produced by prostacyclin (PGI2) and prostaglandin E2 (PGE2) in dogs. An acidified solution of saline was applied topically on the canine gastric mucosa with and without ethanol at various concentrations. Ethano...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198824

    authors: Konturek SJ,Robert A

    更新日期:1982-01-01 00:00:00

  • Effect of cell proliferation on healing of gastric and duodenal ulcers in rats.

    abstract::The healing of acetic acid-induced gastric and duodenal ulcers was examined together with the biochemical indices of growth in gastric and duodenal mucosa in the following three groups of rats: (a) chow-fed, (b) fed an isocaloric liquid diet, (c) fed the liquid diet plus pentagastrin injections (250 micrograms/kg, 3 t...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000199280

    authors: Takeuchi K,Johnson LR

    更新日期:1986-01-01 00:00:00

  • The role of catecholamines in the control of gastrin and acid secretion during insulin hypoglycaemia in man.

    abstract::5 adrenalectomized subjects and 8 healthy volunteers underwent an insulin test during which acid secretion and plasma adrenaline, noradrenaline, dopamine and gastrin concentrations were measured. Plasma glucose concentration fell by greater than 50% in all subjects. The mean plasma adrenaline concentration increased m...

    journal_title:Digestion

    pub_type: 杂志文章

    doi:10.1159/000198547

    authors: Järhult J,Hamberger B,Lanthén G,Ors M,Uvnäs-Wallensten K

    更新日期:1981-01-01 00:00:00